Inborn Errors of Biochemistry

MEDS 4031  |  2 credit hours  | Spring Semester  |  Syllabus not yet available

W 9:00 – 10:20 PM

Michael Lieberman, PhD  |   michael.lieberman@uc.edu  |  513-558-5645

The course is designed as a seminar course for advanced students in biochemistry. Students will lead a weekly discussion about a biochemical disorder caused by a mutation. The genetics, type of mutation, the effect of the mutation on protein structure, and consequences of the mutation on metabolic pathways will be discussed. The symptoms exhibited by the patients with these mutations will be explained at the molecular level. Current medical treatments for the disorder will also be discussed. In addition, students will be assigned a current paper from the literature to critique as part of their presentation on the disorder. Student grades will be based on their presentations and an exam at the end of the course covering the diseases discussed in class that semester.

Prerequisites

To enroll in this course you must have:

• Earned a minimum grade of C– in MEDS3020 Introduction to Medical Biochemistry or min grade C-, or
• Earned a minimum grade of C– in MEDS4028 Principles of Biochemistry II

Textbook

Jeremy M Berg, John L Tymoczko, Lubert Stryer (2012) Biochemistry, 7e, W. H. Freeman, New York
Hardback ISBN: 978-1-4292-2936-4
E-Book ISBN: 978-1-4292-3129-9
On Reserve at the Health Sciences Library—Call number QU 4 S928b 2012