Plas Laboratory

Publications

2023

Shin, Sejeong; Han, Min-Joon; Jedrychowski, Mark P; Zhang, Ziyang; Shokat, Kevan M; Plas, David R; Dephoure, Noah; Yoon, Sang-Oh 2023. mTOR inhibition reprograms cellular proteostasis by regulating eIF3D-mediated selective mRNA translation and promotes cell phenotype switching. Cell reports, 42 8, 112868

Garrett, Matthew C; Albano, Rebecca; Carnwath, Troy; Elahi, Lubayna; Behrmann, Catherine A; Pemberton, Merissa; Woo, Daniel; O'Brien, Eric; VanCauwenbergh, Brett; Perentesis, John; Shah, Sanjit; Hagan, Matthew; Kendler, Ady; Zhao, Chuntao; Paranjpe, Aditi; Roskin, Krishna; Kornblum, Harley; Plas, David R; Lu, Q Richard 2023. HDAC1 and HDAC6 are essential for driving growth in IDH1 mutant glioma. Scientific reports, 13 1, 12433

Verma, Rita; Aggarwal, Parul; Bischoff, Megan E; Reigle, James; Secic, Dina; Wetzel, Collin; VandenHeuvel, Katherine; Biesiada, Jacek; Ehmer, Birgit; Landero Figueroa, Julio A; Plas, David R; Medvedovic, Mario; Meller, Jarek; Czyzyk-Krzeska, Maria F 2023. Microtubule-associated protein MAP1LC3C regulates lysosomal exocytosis and induces zinc reprogramming in renal cancer cells. The Journal of biological chemistry, 299 5, 104663

2022

Karve, Aniruddha S; Desai, Janki M; Dave, Nimita; Wise-Draper, Trisha M; Gudelsky, Gary A; Phoenix, Timothy N; DasGupta, Biplab; Sengupta, Soma; Plas, David R; Desai, Pankaj B 2022. Potentiation of temozolomide activity against glioblastoma cells by aromatase inhibitor letrozole. Cancer chemotherapy and pharmacology, 90 4, 345-356

Garrett, Matthew C; Albano, Rebecca; Carnwath, Troy; Shah, Sanjit; Woo, Daniel; Lamba, Michael; Plas, David R; Paranjpe, Aditi; Roskin, Krishna; Zhao, Chuntao; Lu, Richard 2022. Chromatin structure predicts survival in glioma patients. Scientific reports, 12 1, 8221

2021

Wang, Chenran; Haas, Michael A; Yeo, Syn Kok; Paul, Ritama; Yang, Fuchun; Vallabhapurapu, Subrahmanya; Qi, Xiaoyang; Plas, David R; Guan, Jun-Lin 2021. Autophagy mediated lipid catabolism facilitates glioma progression to overcome bioenergetic crisis. British journal of cancer, ,

Czyzyk-Krzeska, Maria F; Landero Figueroa, Julio A; Gulati, Shuchi; Cunningham, John T; Meller, Jarek; ShamsaeI, Behrouz; Vemuri, Bhargav; Plas, David R 2021. Molecular and Metabolic Subtypes in Sporadic and Inherited Clear Cell Renal Cell Carcinoma. Genes, 12 3,

Qing, Ying; Dong, Lei; Gao, Lei; Li, Chenying; Li, Yangchan; Han, Li; Prince, Emily; Tan, Brandon; Deng, Xiaolan; Wetzel, Collin; Shen, Chao; Gao, Min; Chen, Zhenhua; Li, Wei; Zhang, Bin; Braas, Daniel; Ten Hoeve, Johanna; Sanchez, Gerardo Javier; Chen, Huiying; Chan, Lai N; Chen, Chun-Wei; Ann, David; Jiang, Lei; Müschen, Markus; Marcucci, Guido; Plas, David R; Li, Zejuan; Su, Rui; Chen, Jianjun 2021. R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis. Molecular cell, 81 5, 922-939.e9

Czyzyk-Krzeska, Maria F; Meller, Jarek; Landero Figueroa, Julio A; Plas, David R; Cunningham, John T 2021. Metabolic subtypes of clear cell renal cell carcinoma defined by tobacco smoking. Molecular & cellular oncology, 8 2, 1859917

Koehler, Abigail; Karve, Aniruddha; Desai, Pankaj; Arbiser, Jack; Plas, David R; Qi, Xiaoyang; Read, Renee D; Sasaki, Atsuo T; Gawali, Vaibhavkumar S; Toukam, Donatien K; Bhattacharya, Debanjan; Kallay, Laura; Pomeranz Krummel, Daniel A; Sengupta, Soma 2021. Reuse of Molecules for Glioblastoma Therapy. Pharmaceuticals (Basel, Switzerland), 14 2,

Reigle, James; Secic, Dina; Biesiada, Jacek; Wetzel, Collin; Shamsaei, Behrouz; Chu, Johnson; Zang, Yuanwei; Zhang, Xiang; Talbot, Nicholas J; Bischoff, Megan E; Zhang, Yongzhen; Thakar, Charuhas V; Gaitonde, Krishnanath; Sidana, Abhinav; Bui, Hai; Cunningham, John T; Zhang, Qing; Schmidt, Laura S; Linehan, W Marston; Medvedovic, Mario; Plas, David R; Figueroa, Julio A Landero; Meller, Jarek; Czyzyk-Krzeska, Maria F 2021. Tobacco smoking induces metabolic reprogramming of renal cell carcinoma. The Journal of clinical investigation, 131 1,

Bischoff, Megan E; Zang, Yuanwei; Chu, Johnson; Price, Adam D; Ehmer, Birgit; Talbot, Nicholas J; Newbold, Michael J; Paul, Anurag; Guan, Jun-Lin; Plas, David R; Meller, Jarek; Czyzyk-Krzeska, Maria F 2021. Selective MAP1LC3C (LC3C) autophagy requires noncanonical regulators and the C-terminal peptide. The Journal of cell biology, 220 7,

2020

Ren, Yan; Sivaganesan, Siva; Clark, Nicholas A; Zhang, Lixia; Biesiada, Jacek; Niu, Wen; Plas, David R; Medvedovic, Mario 2020. Predicting mechanism of action of cellular perturbations with pathway activity signatures. Bioinformatics (Oxford, England), ,

Sarma, Pranjal; Plas, David R 2020. Choreography of methylation: KDM4C histone demethylation enables ALKBH5 m6A RNA demethylation to sustain AML stem cells. Blood science (Baltimore, Md.), 2 4, 144-145