Education/CredentialsPhD: Walden UniversityFollowship: Medical University of South Carolina (Stroke and Neuroscience)Fellowship: Emory University School of Medicine (Bone Marrow Transplantation)MPH: University of LiverpoolFellowship: Morehouse School of Medicine (Genomics and Hemoglobinopathies)Residency: Jos University Teaching HospitalMBBS: University of Jos (Faculty of Medicine Sciences ) Contact Information Medical Sciences Building 7210 Office 513-558-6537 Email hyacinhi@ucmail.uc.edu Research InterestsBroadly, my research is focused on understanding the biological basis for disparity in stroke, cognitive impairment and dementia. Specifically, my research has and is examining the role of the sickle cell mutation and other genetic variants on the incidence and prevalence of cerebral macro and microvascular pathologies in individuals of African ancestry. In addition, we also seek to define the mechanisms by which genetic variation in populations, results in differential risk, susceptibility and/or pro... Peer Reviewed Publications Gbotosho, Oluwabukola T; Gollamudi, Jahnavi; Hyacinth, Hyacinth I 2023. The Role of Inflammation in The Cellular and Molecular Mechanisms of Cardiopulmonary Complications of Sickle Cell Disease. Biomolecules, 13 2, Gbotosho, Oluwabukola T; Li, Wei; Joiner, Clinton H; Brown, Lou Ann S; Hyacinth, Hyacinth I 2023. The inflammatory profiles of pulmonary alveolar macrophages and alveolar type 2 cells in SCD. Experimental biology and medicine (Maywood, N.J.), , 15353702231157940Myserlis, Evangelos Pavlos; Georgakis, Marios K; Demel, Stacie L; Sekar, Padmini; Chung, Jaeyoon; Malik, Rainer; Hyacinth, Hyacinth I; Comeau, Mary E; Falcone, Guido J; Langefeld, Carl D; Rosand, Jonathan; Woo, Daniel; Anderson, Christopher D 2023. A Genomic Risk Score Identifies Individuals at High Risk for Intracerebral Hemorrhage. Stroke, 54 4, 973-982Sawyer, Russell P; Worrall, Bradford B; Howard, Virginia J; Crowe, Michael G; Howard, George; Hyacinth, Hyacinth I 2023. Methods of a Study to Assess the Contribution of Cerebral Small Vessel Disease and Dementia Risk Alleles to Racial Disparities in Vascular Cognitive Impairment and Dementia. Journal of the American Heart Association, , e030925Abi Rached, Noor Mary; Gbotosho, Oluwabukola T; Archer, David R; Jones, Jayre A; Sterling, Morgan S; Hyacinth, Hyacinth I 2022. Adhesion molecules and cerebral microvascular hemodynamic abnormalities in sickle cell disease. Frontiers in neurology, 13 , 976063Idris, Ibrahim M; Botchwey, Edward A; Hyacinth, Hyacinth I 2022. Sickle cell disease as an accelerated aging syndrome. Experimental biology and medicine (Maywood, N.J.), , 15353702211068522Mishra, Aniket; Malik, Rainer; Hachiya, Tsuyoshi; Jürgenson, Tuuli; Namba, Shinichi; Posner, Daniel C; Kamanu, Frederick K; Koido, Masaru; Le Grand, Quentin; Shi, Mingyang; He, Yunye; Georgakis, Marios K; Caro, Ilana; Krebs, Kristi; Liaw, Yi-Ching; Vaura, Felix C; Lin, Kuang; Winsvold, Bendik Slagsvold; Srinivasasainagendra, Vinodh; Parodi, Livia; Bae, Hee-Joon; Chauhan, Ganesh; Chong, Michael R; Tomppo, Liisa; Akinyemi, Rufus; Roshchupkin, Gennady V; Habib, Naomi; Jee, Yon Ho; Thomassen, Jesper Qvist; Abedi, Vida; Cárcel-Márquez, Jara; Nygaard, Marianne; Leonard, Hampton L; Yang, Chaojie; Yonova-Doing, Ekaterina; Knol, Maria J; Lewis, Adam J; Judy, Renae L; Ago, Tetsuro; Amouyel, Philippe; Armstrong, Nicole D; Bakker, Mark K; Bartz, Traci M; Bennett, David A; Bis, Joshua C; Bordes, Constance; Børte, Sigrid; Cain, Anael; Ridker, Paul M; Cho, Kelly; Chen, Zhengming; Cruchaga, Carlos; Cole, John W; de Jager, Phil L; de Cid, Rafael; Endres, Matthias; Ferreira, Leslie E; Geerlings, Mirjam I; Gasca, Natalie C; Gudnason, Vilmundur; Hata, Jun; He, Jing; Heath, Alicia K; Ho, Yuk-Lam; Havulinna, Aki S; Hopewell, Jemma C; Hyacinth, Hyacinth I; Inouye, Michael; Jacob, Mina A; Jeon, Christina E; Jern, Christina; Kamouchi, Masahiro; Keene, Keith L; Kitazono, Takanari; Kittner, Steven J; Konuma, Takahiro; Kumar, Amit; Lacaze, Paul; Launer, Lenore J; Lee, Keon-Joo; Lepik, Kaido; Li, Jiang; Li, Liming; Manichaikul, Ani; Markus, Hugh S; Marston, Nicholas A; Meitinger, Thomas; Mitchell, Braxton D; Montellano, Felipe A; Morisaki, Takayuki; Mosley, Thomas H; Nalls, Mike A; Nordestgaard, Børge G; O'Donnell, Martin J; Okada, Yukinori; Onland-Moret, N Charlotte; Ovbiagele, Bruce; Peters, Annette; Psaty, Bruce M; Rich, Stephen S; Rosand, Jonathan; Sabatine, Marc S; Sacco, Ralph L; Saleheen, Danish; Sandset, Else Charlotte; Salomaa, Veikko; Sargurupremraj, Muralidharan; Sasaki, Makoto; Satizabal, Claudia L; Schmidt, Carsten O; Shimizu, Atsushi; Smith, Nicholas L; Sloane, Kelly L; Sutoh, Yoichi; Sun, Yan V; Tanno, Kozo; Tiedt, Steffen; Tatlisumak, Turgut; Torres-Aguila, Nuria P; Tiwari, Hemant K; Trégouët, David-Alexandre; Trompet, Stella; Tuladhar, Anil Man; Tybjærg-Hansen, Anne; van Vugt, Marion; Vibo, Riina; Verma, Shefali S; Wiggins, Kerri L; Wennberg, Patrik; Woo, Daniel; Wilson, Peter W F; Xu, Huichun; Yang, Qiong; Yoon, Kyungheon ; Millwood, Iona Y; Gieger, Christian; Ninomiya, Toshiharu; Grabe, Hans J; Jukema, J Wouter; Rissanen, Ina L; Strbian, Daniel; Kim, Young Jin; Chen, Pei-Hsin; Mayerhofer, Ernst; Howson, Joanna M M; Irvin, Marguerite R; Adams, Hieab; Wassertheil-Smoller, Sylvia; Christensen, Kaare; Ikram, Mohammad A; Rundek, Tatjana; Worrall, Bradford B; Lathrop, G Mark; Riaz, Moeen; Simonsick, Eleanor M; Kõrv, Janika; França, Paulo H C; Zand, Ramin; Prasad, Kameshwar; Frikke-Schmidt, Ruth; de Leeuw, Frank-Erik; Liman, Thomas; Haeusler, Karl Georg; Ruigrok, Ynte M; Heuschmann, Peter Ulrich; Longstreth, W T; Jung, Keum Ji; Bastarache, Lisa; Paré, Guillaume; Damrauer, Scott M; Chasman, Daniel I; Rotter, Jerome I; Anderson, Christopher D; Zwart, John-Anker; Niiranen, Teemu J; Fornage, Myriam; Liaw, Yung-Po; Seshadri, Sudha; Fernández-Cadenas, Israel; Walters, Robin G; Ruff, Christian T; Owolabi, Mayowa O; Huffman, Jennifer E; Milani, Lili; Kamatani, Yoichiro; Dichgans, Martin; Debette, Stephanie 2022. Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries. Nature, 612 7938, E7Mishra, Aniket; Malik, Rainer; Hachiya, Tsuyoshi; Jürgenson, Tuuli; Namba, Shinichi; Posner, Daniel C; Kamanu, Frederick K; Koido, Masaru; Le Grand, Quentin; Shi, Mingyang; He, Yunye; Georgakis, Marios K; Caro, Ilana; Krebs, Kristi; Liaw, Yi-Ching; Vaura, Felix C; Lin, Kuang; Winsvold, Bendik Slagsvold; Srinivasasainagendra, Vinodh; Parodi, Livia; Bae, Hee-Joon; Chauhan, Ganesh; Chong, Michael R; Tomppo, Liisa; Akinyemi, Rufus; Roshchupkin, Gennady V; Habib, Naomi; Jee, Yon Ho; Thomassen, Jesper Qvist; Abedi, Vida; Cárcel-Márquez, Jara; Nygaard, Marianne; Leonard, Hampton L; Yang, Chaojie; Yonova-Doing, Ekaterina; Knol, Maria J; Lewis, Adam J; Judy, Renae L; Ago, Tetsuro; Amouyel, Philippe; Armstrong, Nicole D; Bakker, Mark K; Bartz, Traci M; Bennett, David A; Bis, Joshua C; Bordes, Constance; Børte, Sigrid; Cain, Anael; Ridker, Paul M; Cho, Kelly; Chen, Zhengming; Cruchaga, Carlos; Cole, John W; de Jager, Phil L; de Cid, Rafael; Endres, Matthias; Ferreira, Leslie E; Geerlings, Mirjam I; Gasca, Natalie C; Gudnason, Vilmundur; Hata, Jun; He, Jing; Heath, Alicia K; Ho, Yuk-Lam; Havulinna, Aki S; Hopewell, Jemma C; Hyacinth, Hyacinth I; Inouye, Michael; Jacob, Mina A; Jeon, Christina E; Jern, Christina; Kamouchi, Masahiro; Keene, Keith L; Kitazono, Takanari; Kittner, Steven J; Konuma, Takahiro; Kumar, Amit; Lacaze, Paul; Launer, Lenore J; Lee, Keon-Joo; Lepik, Kaido; Li, Jiang; Li, Liming; Manichaikul, Ani; Markus, Hugh S; Marston, Nicholas A; Meitinger, Thomas; Mitchell, Braxton D; Montellano, Felipe A; Morisaki, Takayuki; Mosley, Thomas H; Nalls, Mike A; Nordestgaard, Børge G; O'Donnell, Martin J; Okada, Yukinori; Onland-Moret, N Charlotte; Ovbiagele, Bruce; Peters, Annette; Psaty, Bruce M; Rich, Stephen S; Rosand, Jonathan; Sabatine, Marc S; Sacco, Ralph L; Saleheen, Danish; Sandset, Else Charlotte; Salomaa, Veikko; Sargurupremraj, Muralidharan; Sasaki, Makoto; Satizabal, Claudia L; Schmidt, Carsten O; Shimizu, Atsushi; Smith, Nicholas L; Sloane, Kelly L; Sutoh, Yoichi; Sun, Yan V; Tanno, Kozo; Tiedt, Steffen; Tatlisumak, Turgut; Torres-Aguila, Nuria P; Tiwari, Hemant K; Trégouët, David-Alexandre; Trompet, Stella; Tuladhar, Anil Man; Tybjærg-Hansen, Anne; van Vugt, Marion; Vibo, Riina; Verma, Shefali S; Wiggins, Kerri L; Wennberg, Patrik; Woo, Daniel; Wilson, Peter W F; Xu, Huichun; Yang, Qiong; Yoon, Kyungheon ; Millwood, Iona Y; Gieger, Christian; Ninomiya, Toshiharu; Grabe, Hans J; Jukema, J Wouter; Rissanen, Ina L; Strbian, Daniel; Kim, Young Jin; Chen, Pei-Hsin; Mayerhofer, Ernst; Howson, Joanna M M; Irvin, Marguerite R; Adams, Hieab; Wassertheil-Smoller, Sylvia; Christensen, Kaare; Ikram, Mohammad A; Rundek, Tatjana; Worrall, Bradford B; Lathrop, G Mark; Riaz, Moeen; Simonsick, Eleanor M; Kõrv, Janika; França, Paulo H C; Zand, Ramin; Prasad, Kameshwar; Frikke-Schmidt, Ruth; de Leeuw, Frank-Erik; Liman, Thomas; Haeusler, Karl Georg; Ruigrok, Ynte M; Heuschmann, Peter Ulrich; Longstreth, W T; Jung, Keum Ji; Bastarache, Lisa; Paré, Guillaume; Damrauer, Scott M; Chasman, Daniel I; Rotter, Jerome I; Anderson, Christopher D; Zwart, John-Anker; Niiranen, Teemu J; Fornage, Myriam; Liaw, Yung-Po; Seshadri, Sudha; Fernández-Cadenas, Israel; Walters, Robin G; Ruff, Christian T; Owolabi, Mayowa O; Huffman, Jennifer E; Milani, Lili; Kamatani, Yoichiro; Dichgans, Martin; Debette, Stephanie 2022. Stroke genetics informs drug discovery and risk prediction across ancestries. Nature, 611 7934, 115-123Muratoglu, Selen C; Charette, Marc F; Galis, Zorina S; Greenstein, Adam S; Daugherty, Alan; Joutel, Anne; Kozel, Beth A; Wilcock, Donna M; Collins, Emily C; Sorond, Farzaneh A; Howell, Gareth R; Hyacinth, Hyacinth I; Lloyd, Kent K C; Stenmark, Kurt R; Boehm, Manfred; Kahn, Mark L; Corriveau, Roderick; Wells, Sara; Bussey, Timothy J; Sukoff Rizzo, Stacey J; Iruela-Arispe, M Luisa 2022. Perspectives on Cognitive Phenotypes and Models of Vascular Disease. Arteriosclerosis, thrombosis, and vascular biology, 42 7, 831-838Sawyer, Russell P; Pun, Sirjana; Karkoska, Kristine A; Clendinen, Cherita A; DeBaun, Michael R; Gutmark, Ephraim; Barrile, Riccardo; Hyacinth, Hyacinth I 2022. Effect of Blood Transfusion on Cerebral Hemodynamics and Vascular Topology Described by Computational Fluid Dynamics in Sickle Cell Disease Patients. Brain sciences, 12 10, Hyacinth, Hyacinth I; Franceschini, Nora; Seals, Samantha R; Irvin, Marguerite R; Chaudhary, Ninad; Naik, Rakhi P; Alonso, Alvaro; Carty, Cara L; Burke, Gregory L; Zakai, Neil A; Winkler, Cheryl A; David, Victor A; Kopp, Jeffrey B; Judd, Suzanne E; Adams, Robert J; Gee, Beatrice E; Longstreth, W T; Egede, Leonard; Lackland, Daniel T; Greenberg, Charles S; Taylor, Herman; Manson, JoAnn E; Key, Nigel S; Derebail, Vimal K; Kshirsagar, Abhijit V; Folsom, Aaron R; Konety, Suma H; Howard, Virginia; Allison, Matthew; Wilson, James G; Correa, Adolfo; Zhi, Degui; Arnett, Donna K; Howard, George; Reiner, Alexander P; Cushman, Mary; Safford, Monika M 2021. Association of Sickle Cell Trait With Incidence of Coronary Heart Disease Among African American Individuals. JAMA network open, 4 1, e2030435Nartey, Eunice Berko; Spector, Jonathan; Adu-Afarwuah, Seth; Jones, Catherine L; Jackson, Alan; Ohemeng, Agartha; Shah, Rajiv; Koryo-Dabrah, Alice; Kuma, Amma Benneh-Akwasi; Hyacinth, Hyacinth I; Steiner-Asiedu, Matilda 2021. Nutritional perspectives on sickle cell disease in Africa: a systematic review. BMC nutrition, 7 1, 9Prapiadou, Savvina; Demel, Stacie L; Hyacinth, Hyacinth I 2021. Genetic and Genomic Epidemiology of Stroke in People of African Ancestry. Genes, 12 11, Chen, Nemin; Caruso, Christina; Alonso, Alvaro; Derebail, Vimal K; Kshirsagar, Abhijit V; Sharrett, A Richey; Key, Nigel S; Gottesman, Rebecca F; Grove, Megan L; Bressler, Jan; Boerwinkle, Eric; Windham, B Gwen; Mosley, Thomas H; Hyacinth, Hyacinth I 2020. Corrigendum to 'Association of sickle cell trait with measures of cognitive function and dementia in African Americans' eNeurologicalSci, Vol. 16 (2019), 100,201. eNeurologicalSci, 21 , 100281Hardy, Raven A; Rached, Noor Abi; Jones, Jayre A; Archer, David R; Hyacinth, Hyacinth I 2020. Role of age and neuroinflammation in the mechanism of cognitive deficits in sickle cell disease. Experimental biology and medicine (Maywood, N.J.), , 1535370220958011Holshouser, Steven; Cafiero, Rebecca; Robinson, Mayra; Kirkpatrick, Joy; Casero, Robert A; Hyacinth, Hyacinth I; Woster, Patrick M 2020. Epigenetic Reexpression of Hemoglobin F Using Reversible LSD1 Inhibitors: Potential Therapies for Sickle Cell Disease. ACS omega, 5 24, 14750-14758Hyacinth, Hyacinth I; Idris, Ibrahim M 2020. Cognitive deficit in sickle cell disease: Is hydroxyurea part of the story? British journal of haematology, 189 6, 1014-1015Keene, Keith L; Hyacinth, Hyacinth I; Bis, Joshua C; Kittner, Steven J; Mitchell, Braxton D; Cheng, Yu-Ching; Pare, Guillaume; Chong, Michael; O'Donnell, Martin; Meschia, James F; Chen, Wei-Min; Sale, Michèle M; Rich, Stephen S; Nalls, Mike A; Zonderman, Alan B; Evans, Michele K; Wilson, James G; Correa, Adolfo; Markus, Hugh S; Traylor, Matthew; Lewis, Cathryn M; Carty, Cara L; Reiner, Alexander; Haessler, Jeff; Langefeld, Carl D; Gottesman, Rebecca; Mosley, Thomas H; Woo, Daniel; Yaffe, Kristine; Liu, YongMei; Longstreth, William T; Psaty, Bruce M; Kooperberg, Charles; Lange, Leslie A; Sacco, Ralph; Rundek, Tatjana; Lee, Jin-Moo; Cruchaga, Carlos; Furie, Karen L; Arnett, Donna K; Benavente, Oscar R; Grewal, Raji P; Peddareddygari, Leema Reddy; Dichgans, Martin; Malik, Rainer; Worrall, Bradford B; Fornage, Myriam 2020. Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke. Stroke, 51 8, 2454-2463Chauhan, Ganesh; Adams, Hieab H H; Satizabal, Claudia L; Bis, Joshua C; Teumer, Alexander; Sargurupremraj, Muralidharan; Hofer, Edith; Trompet, Stella; Hilal, Saima; Smith, Albert Vernon; Jian, Xueqiu; Malik, Rainer; Traylor, Matthew; Pulit, Sara L; Amouyel, Philippe; Mazoyer, Bernard; Zhu, Yi-Cheng; Kaffashian, Sara; Schilling, Sabrina; Beecham, Gary W; Montine, Thomas J; Schellenberg, Gerard D; Kjartansson, Olafur; Guðnason, Vilmundur; Knopman, David S; Griswold, Michael E; Windham, B Gwen; Gottesman, Rebecca F; Mosley, Thomas H; Schmidt, Reinhold; Saba, Yasaman; Schmidt, Helena; Takeuchi, Fumihiko; Yamaguchi, Shuhei; Nabika, Toru; Kato, Norihiro; Rajan, Kumar B; Aggarwal, Neelum T; De Jager, Philip L; Evans, Denis A; Psaty, Bruce M; Rotter, Jerome I; Rice, Kenneth; Lopez, Oscar L; Liao, Jiemin; Chen, Christopher; Cheng, Ching-Yu; Wong, Tien Y; Ikram, Mohammad K; van der Lee, Sven J; Amin, Najaf; Chouraki, Vincent; DeStefano, Anita L; Aparicio, Hugo J; Romero, Jose R; Maillard, Pauline; DeCarli, Charles; Wardlaw, Joanna M; Hernández, Maria Del C Valdés; Luciano, Michelle; Liewald, David; Deary, Ian J; Starr, John M; Bastin, Mark E; Muñoz Maniega, Susana; Slagboom, P Eline; Beekman, Marian; Deelen, Joris; Uh, Hae-Won; Lemmens, Robin; Brodaty, Henry; Wright, Margaret J; Ames, David; Boncoraglio, Giorgio B; Hopewell, Jemma C; Beecham, Ashley H; Blanton, Susan H; Wright, Clinton B; Sacco, Ralph L; Wen, Wei; Thalamuthu, Anbupalam; Armstrong, Nicola J; Chong, Elizabeth; Schofield, Peter R; Kwok, John B; van der Grond, Jeroen; Stott, David J; Ford, Ian; Jukema, J Wouter; Vernooij, Meike W; Hofman, Albert; Uitterlinden, André G; van der Lugt, Aad; Wittfeld, Katharina; Grabe, Hans J; Hosten, Norbert; von Sarnowski, Bettina; Völker, Uwe; Levi, Christopher; Jimenez-Conde, Jordi; Sharma, Pankaj; Sudlow, Cathie L M; Rosand, Jonathan; Woo, Daniel; Cole, John W; Meschia, James F; Slowik, Agnieszka; Thijs, Vincent; Lindgren, Arne; Melander, Olle; Grewal, Raji P; Rundek, Tatjana; Rexrode, Kathy; Rothwell, Peter M; Arnett, Donna K; Jern, Christina; Johnson, Julie A; Benavente, Oscar R; Wasssertheil-Smoller, Sylvia; Lee, Jin-Moo; Wong, Quenna; Mitchell, Braxton D; Rich, Stephen S; McArdle, Patrick F; Geerlings, Mirjam I; van der Graaf, Yolanda; de Bakker, Paul I W; Asselbergs, Folkert W; Srikanth, Velandai; Thomson, Russell; McWhirter, Rebekah; Moran, Chris; Callisaya, Michele; Phan, Thanh; Rutten-Jacobs, Loes C A; Bevan, Steve; Tzourio, Christophe; Mather, Karen A; Sachdev, Perminder S; van Duijn, Cornelia M; Worrall, Bradford B; Dichgans, Martin; Kittner, Steven J; Markus, Hugh S; Ikram, Mohammad A; Fornage, Myriam; Launer, Lenore J; Seshadri, Sudha; Longstreth, W T; Debette, Stéphanie 2019. Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting. Neurology, , Chen, Nemin; Caruso, Christina; Alonso, Alvaro; Derebail, Vimal K; Kshirsagar, Abhijit V; Sharrett, A Richey; Key, Nigel S; Gottesman, Rebecca F; Grove, Megan L; Bressler, Jan; Boerwinkle, Eric; Windham, B Gwen; Mosley, Thomas H; Hyacinth, Hyacinth I 2019. Association of sickle cell trait with measures of cognitive function and dementia in African Americans. eNeurologicalSci, 16 , 100201Hyacinth, Hyacinth I; Sugihara, Courtney L; Spencer, Thomas L; Archer, David R; Shih, Andy Y 2019. Higher prevalence of spontaneous cerebral vasculopathy and cerebral infarcts in a mouse model of sickle cell disease. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 39 2, 342-351Larsson, Susanna C; Traylor, Matthew; Burgess, Stephen; Boncoraglio, Giorgio B; Jern, Christina; Michaëlsson, Karl; Markus, Hugh S 2019. Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study. Neurology, 92 9, e944-e950Malik, Rainer; Chauhan, Ganesh; Traylor, Matthew; Sargurupremraj, Muralidharan; Okada, Yukinori; Mishra, Aniket; Rutten-Jacobs, Loes; Giese, Anne-Katrin; van der Laan, Sander W; Gretarsdottir, Solveig; Anderson, Christopher D; Chong, Michael; Adams, Hieab H H; Ago, Tetsuro; Almgren, Peter; Amouyel, Philippe; Ay, Hakan; Bartz, Traci M; Benavente, Oscar R; Bevan, Steve; Boncoraglio, Giorgio B; Brown, Robert D; Butterworth, Adam S; Carrera, Caty; Carty, Cara L; Chasman, Daniel I; Chen, Wei-Min; Cole, John W; Correa, Adolfo; Cotlarciuc, Ioana; Cruchaga, Carlos; Danesh, John; de Bakker, Paul I W; DeStefano, Anita L; den Hoed, Marcel; Duan, Qing; Engelter, Stefan T; Falcone, Guido J; Gottesman, Rebecca F; Grewal, Raji P; Gudnason, Vilmundur; Gustafsson, Stefan; Haessler, Jeffrey; Harris, Tamara B; Hassan, Ahamad; Havulinna, Aki S; Heckbert, Susan R; Holliday, Elizabeth G; Howard, George; Hsu, Fang-Chi; Hyacinth, Hyacinth I; Ikram, M Arfan; Ingelsson, Erik; Irvin, Marguerite R; Jian, Xueqiu; Jiménez-Conde, Jordi; Johnson, Julie A; Jukema, J Wouter; Kanai, Masahiro; Keene, Keith L; Kissela, Brett M; Kleindorfer, Dawn O; Kooperberg, Charles; Kubo, Michiaki; Lange, Leslie A; Langefeld, Carl D; Langenberg, Claudia; Launer, Lenore J; Lee, Jin-Moo; Lemmens, Robin; Leys, Didier; Lewis, Cathryn M; Lin, Wei-Yu; Lindgren, Arne G; Lorentzen, Erik; Magnusson, Patrik K; Maguire, Jane; Manichaikul, Ani; McArdle, Patrick F; Meschia, James F; Mitchell, Braxton D; Mosley, Thomas H; Nalls, Michael A; Ninomiya, Toshiharu; O'Donnell, Martin J; Psaty, Bruce M; Pulit, Sara L; Rannikmäe, Kristiina; Reiner, Alexander P; Rexrode, Kathryn M; Rice, Kenneth; Rich, Stephen S; Ridker, Paul M; Rost, Natalia S; Rothwell, Peter M; Rotter, Jerome I; Rundek, Tatjana; Sacco, Ralph L; Sakaue, Saori; Sale, Michele M; Salomaa, Veikko; Sapkota, Bishwa R; Schmidt, Reinhold; Schmidt, Carsten O; Schminke, Ulf; Sharma, Pankaj; Slowik, Agnieszka; Sudlow, Cathie L M; Tanislav, Christian; Tatlisumak, Turgut; Taylor, Kent D; Thijs, Vincent N S; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Tiedt, Steffen; Trompet, Stella; Tzourio, Christophe; van Duijn, Cornelia M; Walters, Matthew; Wareham, Nicholas J; Wassertheil-Smoller, Sylvia; Wilson, James G; Wiggins, Kerri L; Yang, Qiong; Yusuf, Salim ; Bis, Joshua C; Pastinen, Tomi; Ruusalepp, Arno; Schadt, Eric E; Koplev, Simon; Björkegren, Johan L M; Codoni, Veronica; Civelek, Mete; Smith, Nicholas L; Trégouët, David A; Christophersen, Ingrid E; Roselli, Carolina; Lubitz, Steven A; Ellinor, Patrick T; Tai, E Shyong; Kooner, Jaspal S; Kato, Norihiro; He, Jiang; van der Harst, Pim; Elliott, Paul; Chambers, John C; Takeuchi, Fumihiko; Johnson, Andrew D ; Sanghera, Dharambir K; Melander, Olle; Jern, Christina; Strbian, Daniel; Fernandez-Cadenas, Israel; Longstreth, W T; Rolfs, Arndt; Hata, Jun; Woo, Daniel; Rosand, Jonathan; Pare, Guillaume; Hopewell, Jemma C; Saleheen, Danish; Stefansson, Kari; Worrall, Bradford B; Kittner, Steven J; Seshadri, Sudha; Fornage, Myriam; Markus, Hugh S; Howson, Joanna M M; Kamatani, Yoichiro; Debette, Stephanie; Dichgans, Martin 2019. Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. Nature genetics, 51 7, 1192-1193Franceschini, Nora; Giambartolomei, Claudia; de Vries, Paul S; Finan, Chris; Bis, Joshua C; Huntley, Rachael P; Lovering, Ruth C; Tajuddin, Salman M; Winkler, Thomas W; Graff, Misa; Kavousi, Maryam; Dale, Caroline; Smith, Albert V; Hofer, Edith; van Leeuwen, Elisabeth M; Nolte, Ilja M; Lu, Lingyi; Scholz, Markus; Sargurupremraj, Muralidharan; Pitkänen, Niina; Franzén, Oscar; Joshi, Peter K; Noordam, Raymond; Marioni, Riccardo E; Hwang, Shih-Jen; Musani, Solomon K; Schminke, Ulf; Palmas, Walter; Isaacs, Aaron; Correa, Adolfo; Zonderman, Alan B; Hofman, Albert; Teumer, Alexander; Cox, Amanda J; Uitterlinden, André G; Wong, Andrew; Smit, Andries J; Newman, Anne B; Britton, Annie; Ruusalepp, Arno; Sennblad, Bengt; Hedblad, Bo; Pasaniuc, Bogdan; Penninx, Brenda W; Langefeld, Carl D; Wassel, Christina L; Tzourio, Christophe; Fava, Cristiano; Baldassarre, Damiano; O'Leary, Daniel H; Teupser, Daniel; Kuh, Diana; Tremoli, Elena; Mannarino, Elmo; Grossi, Enzo; Boerwinkle, Eric; Schadt, Eric E; Ingelsson, Erik; Veglia, Fabrizio; Rivadeneira, Fernando; Beutner, Frank; Chauhan, Ganesh; Heiss, Gerardo; Snieder, Harold; Campbell, Harry; Völzke, Henry; Markus, Hugh S; Deary, Ian J; Jukema, J Wouter; de Graaf, Jacqueline; Price, Jacqueline; Pott, Janne; Hopewell, Jemma C; Liang, Jingjing; Thiery, Joachim; Engmann, Jorgen; Gertow, Karl; Rice, Kenneth; Taylor, Kent D; Dhana, Klodian; Kiemeney, Lambertus A L M; Lind, Lars; Raffield, Laura M; Launer, Lenore J; Holdt, Lesca M; Dörr, Marcus; Dichgans, Martin; Traylor, Matthew; Sitzer, Matthias; Kumari, Meena; Kivimaki, Mika; Nalls, Mike A; Melander, Olle; Raitakari, Olli; Franco, Oscar H; Rueda-Ochoa, Oscar L; Roussos, Panos; Whincup, Peter H; Amouyel, Philippe; Giral, Philippe; Anugu, Pramod; Wong, Quenna; Malik, Rainer; Rauramaa, Rainer; Burkhardt, Ralph; Hardy, Rebecca; Schmidt, Reinhold; de Mutsert, Renée; Morris, Richard W; Strawbridge, Rona J; Wannamethee, S Goya; Hägg, Sara; Shah, Sonia; McLachlan, Stela; Trompet, Stella; Seshadri, Sudha; Kurl, Sudhir; Heckbert, Susan R; Ring, Susan; Harris, Tamara B; Lehtimäki, Terho; Galesloot, Tessel E; Shah, Tina; de Faire, Ulf; Plagnol, Vincent; Rosamond, Wayne D; Post, Wendy; Zhu, Xiaofeng; Zhang, Xiaoling; Guo, Xiuqing; Saba, Yasaman ; Dehghan, Abbas; Seldenrijk, Adrie; Morrison, Alanna C; Hamsten, Anders; Psaty, Bruce M; van Duijn, Cornelia M; Lawlor, Deborah A; Mook-Kanamori, Dennis O; Bowden, Donald W; Schmidt, Helena; Wilson, James F; Wilson, James G; Rotter, Jerome I; Wardlaw, Joanna M; Deanfield, John; Halcox, Julian; Lyytikäinen, Leo-Pekka; Loeffler, Markus; Evans, Michele K; Debette, Stéphanie; Humphries, Steve E; Völker, Uwe; Gudnason, Vilmundur; Hingorani, Aroon D; Björkegren, Johan L M; Casas, Juan P; O'Donnell, Christopher J 2018. GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes. Nature communications, 9 1, 5141Gutiérrez, Orlando M; Irvin, Marguerite R; Chaudhary, Ninad S; Cushman, Mary; Zakai, Neil A; David, Victor A; Limou, Sophie; Pamir, Nathalie; Reiner, Alex P; Naik, Rakhi P; Sale, Michele M; Safford, Monika M; Hyacinth, Hyacinth I; Judd, Suzanne E; Kopp, Jeffrey B; Winkler, Cheryl A 2018. APOL1 Nephropathy Risk Variants and Incident Cardiovascular Disease Events in Community-Dwelling Black Adults. Circulation. Genomic and precision medicine, 11 6, e002098Hartmann, David A; Hyacinth, Hyacinth I; Liao, Francesca-Fang; Shih, Andy Y 2018. Does pathology of small venules contribute to cerebral microinfarcts and dementia? Journal of neurochemistry, 144 5, 517-526Hyacinth, Hyacinth I 2018. The injured brain might need more fat! EBioMedicine, 33 , 12-13Hyacinth, Hyacinth I 2018. Sickle-cell anaemia needs more food? The Lancet. Haematology, 5 4, e130-e131Hyacinth, Hyacinth I; Carty, Cara L; Seals, Samantha R; Irvin, Marguerite R; Naik, Rakhi P; Burke, Gregory L; Zakai, Neil A; Wilson, James G; Franceschini, Nora; Winkler, Cheryl A; David, Victor A; Kopp, Jeffrey B; Judd, Suzanne E; Adams, Robert J; Longstreth, W T; Egede, Leonard; Lackland, Daniel T; Taylor, Herman; Manson, JoAnn E; Howard, Virginia; Allison, Matthew; Gee, Beatrice E; Correa, Adolfo; Safford, Monika M; Arnett, Donna K; Howard, George; Reiner, Alexander P; Cushman, Mary 2018. Association of Sickle Cell Trait With Ischemic Stroke Among African Americans: A Meta-analysis. JAMA neurology, 75 7, 802-807Malik, Rainer; Chauhan, Ganesh; Traylor, Matthew; Sargurupremraj, Muralidharan; Okada, Yukinori; Mishra, Aniket; Rutten-Jacobs, Loes; Giese, Anne-Katrin; van der Laan, Sander W; Gretarsdottir, Solveig; Anderson, Christopher D; Chong, Michael; Adams, Hieab H H; Ago, Tetsuro; Almgren, Peter; Amouyel, Philippe; Ay, Hakan; Bartz, Traci M; Benavente, Oscar R; Bevan, Steve; Boncoraglio, Giorgio B; Brown, Robert D; Butterworth, Adam S; Carrera, Caty; Carty, Cara L; Chasman, Daniel I; Chen, Wei-Min; Cole, John W; Correa, Adolfo; Cotlarciuc, Ioana; Cruchaga, Carlos; Danesh, John; de Bakker, Paul I W; DeStefano, Anita L; den Hoed, Marcel; Duan, Qing; Engelter, Stefan T; Falcone, Guido J; Gottesman, Rebecca F; Grewal, Raji P; Gudnason, Vilmundur; Gustafsson, Stefan; Haessler, Jeffrey; Harris, Tamara B; Hassan, Ahamad; Havulinna, Aki S; Heckbert, Susan R; Holliday, Elizabeth G; Howard, George; Hsu, Fang-Chi; Hyacinth, Hyacinth I; Ikram, M Arfan; Ingelsson, Erik; Irvin, Marguerite R; Jian, Xueqiu; Jiménez-Conde, Jordi; Johnson, Julie A; Jukema, J Wouter; Kanai, Masahiro; Keene, Keith L; Kissela, Brett M; Kleindorfer, Dawn O; Kooperberg, Charles; Kubo, Michiaki; Lange, Leslie A; Langefeld, Carl D; Langenberg, Claudia; Launer, Lenore J; Lee, Jin-Moo; Lemmens, Robin; Leys, Didier; Lewis, Cathryn M; Lin, Wei-Yu; Lindgren, Arne G; Lorentzen, Erik; Magnusson, Patrik K; Maguire, Jane; Manichaikul, Ani; McArdle, Patrick F; Meschia, James F; Mitchell, Braxton D; Mosley, Thomas H; Nalls, Michael A; Ninomiya, Toshiharu; O'Donnell, Martin J; Psaty, Bruce M; Pulit, Sara L; Rannikmäe, Kristiina; Reiner, Alexander P; Rexrode, Kathryn M; Rice, Kenneth; Rich, Stephen S; Ridker, Paul M; Rost, Natalia S; Rothwell, Peter M; Rotter, Jerome I; Rundek, Tatjana; Sacco, Ralph L; Sakaue, Saori; Sale, Michele M; Salomaa, Veikko; Sapkota, Bishwa R; Schmidt, Reinhold; Schmidt, Carsten O; Schminke, Ulf; Sharma, Pankaj; Slowik, Agnieszka; Sudlow, Cathie L M; Tanislav, Christian; Tatlisumak, Turgut; Taylor, Kent D; Thijs, Vincent N S; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Tiedt, Steffen; Trompet, Stella; Tzourio, Christophe; van Duijn, Cornelia M; Walters, Matthew; Wareham, Nicholas J; Wassertheil-Smoller, Sylvia; Wilson, James G; Wiggins, Kerri L; Yang, Qiong; Yusuf, Salim ; Bis, Joshua C; Pastinen, Tomi; Ruusalepp, Arno; Schadt, Eric E; Koplev, Simon; Björkegren, Johan L M; Codoni, Veronica; Civelek, Mete; Smith, Nicholas L; Trégouët, David A; Christophersen, Ingrid E; Roselli, Carolina; Lubitz, Steven A; Ellinor, Patrick T; Tai, E Shyong; Kooner, Jaspal S; Kato, Norihiro; He, Jiang; van der Harst, Pim; Elliott, Paul; Chambers, John C; Takeuchi, Fumihiko; Johnson, Andrew D ; Sanghera, Dharambir K; Melander, Olle; Jern, Christina; Strbian, Daniel; Fernandez-Cadenas, Israel; Longstreth, W T; Rolfs, Arndt; Hata, Jun; Woo, Daniel; Rosand, Jonathan; Pare, Guillaume; Hopewell, Jemma C; Saleheen, Danish; Stefansson, Kari; Worrall, Bradford B; Kittner, Steven J; Seshadri, Sudha; Fornage, Myriam; Markus, Hugh S; Howson, Joanna M M; Kamatani, Yoichiro; Debette, Stephanie; Dichgans, Martin 2018. Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. Nature genetics, 50 4, 524-537Shih, Andy Y; Hyacinth, Hyacinth I; Hartmann, David A; van Veluw, Susanne J 2018. Rodent Models of Cerebral Microinfarct and Microhemorrhage. Stroke, 49 3, 803-810Bello, Natalie A; Hyacinth, Hyacinth I; Roetker, Nicholas S; Seals, Samantha R; Naik, Rakhi P; Derebail, Vimal K; Kshirsagar, Abhijit V; Key, Nigel S; Wilson, James G; Correa, Adolfo; Adams, Robert J; Egede, Leonard D; Longstreth, W T; Choudhary, Gaurav; Gee, Beatrice E; Hughes, Austin L; Shah, Amil M; Manson, JoAnn E; Allison, Matthew; Burke, Gregory L; Folsom, Aaron R; Carty, Cara L; Reiner, Alexander P; Solomon, Scott D; Konety, Suma H 2017. Sickle cell trait is not associated with an increased risk of heart failure or abnormalities of cardiac structure and function. Blood, 129 6, 799-801Coleman, Elisheva R; Moudgal, Rohitha; Lang, Kathryn; Hyacinth, Hyacinth I; Awosika, Oluwole O; Kissela, Brett M; Feng, Wuwei 2017. Early Rehabilitation After Stroke: a Narrative Review. Current atherosclerosis reports, 19 12, 59Wright, Racquel J; Lee, Ken S; Hyacinth, Hyacinth I; Hibbert, Jacqueline M; Reid, Marvin E; Wheatley, Andrew O; Asemota, Helen N 2017. An Investigation of the Antioxidant Capacity in Extracts from Moringa oleifera Plants Grown in Jamaica. Plants (Basel, Switzerland), 6 4, Capers, Patrice L; Hyacinth, Hyacinth I; Cue, Shayla; Chappa, Prasanthi; Vikulina, Tatyana; Roser-Page, Susanne; Weitzmann, M Neale; Archer, David R; Newman, Gale W; Quarshie, Alexander; Stiles, Jonathan K; Hibbert, Jacqueline M 2015. Body composition and grip strength are improved in transgenic sickle mice fed a high-protein diet. Journal of nutritional science, 4 , e6Hyacinth, Hyacinth I; Adams, Robert J; Greenberg, Charles S; Voeks, Jenifer H; Hill, Allyson; Hibbert, Jacqueline M; Gee, Beatrice E 2015. Effect of Chronic Blood Transfusion on Biomarkers of Coagulation Activation and Thrombin Generation in Sickle Cell Patients at Risk for Stroke. PloS one, 10 8, e0134193Ellis, Charles; Hyacinth, Hyacinth I; Beckett, Jamie; Feng, Wuwei; Chimowitz, Marc; Ovbiagele, Bruce; Lackland, Dan; Adams, Robert 2014. Racial/Ethnic differences in poststroke rehabilitation outcomes. Stroke research and treatment, 2014 , 950746Hyacinth, Hyacinth I; Adams, Robert J; Voeks, Jenifer H; Hibbert, Jacqueline M; Gee, Beatrice E 2014. Frequent red cell transfusions reduced vascular endothelial activation and thrombogenicity in children with sickle cell anemia and high stroke risk. American journal of hematology, 89 1, 47-51Hyacinth, Hyacinth I; Capers, Patrice L; Archer, David R; Hibbert, Jacqueline M 2014. TNF-?, IFN-?, IL-10, and IL-4 levels were elevated in a murine model of human sickle cell anemia maintained on a high protein/calorie diet. Experimental biology and medicine (Maywood, N.J.), 239 1, 65-70Malek, Angela M; Adams, Robert J; Debenham, Ellen; Boan, Andrea D; Kazley, Abby S; Hyacinth, Hyacinth I; Voeks, Jenifer H; Lackland, Daniel T 2014. Patient awareness and perception of stroke symptoms and the use of 911. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 23 9, 2362-71Manci, Elizabeth Ann; Hyacinth, Hyacinth I; Capers, Patrice L; Archer, David R; Pitts, Sydney; Ghosh, Samit; Patrickson, John; Titford, Michael E; Ofori-Acquah, Solomon F; Hibbert, Jacqueline M 2014. High protein diet attenuates histopathologic organ damage and vascular leakage in transgenic murine model of sickle cell anemia. Experimental biology and medicine (Maywood, N.J.), 239 8, 966-974Naik, Rakhi P; Derebail, Vimal K; Grams, Morgan E; Franceschini, Nora; Auer, Paul L; Peloso, Gina M; Young, Bessie A; Lettre, Guillaume; Peralta, Carmen A; Katz, Ronit; Hyacinth, Hyacinth I; Quarells, Rakale C; Grove, Megan L; Bick, Alexander G; Fontanillas, Pierre; Rich, Stephen S; Smith, Joshua D; Boerwinkle, Eric; Rosamond, Wayne D; Ito, Kaoru; Lanzkron, Sophie; Coresh, Josef; Correa, Adolfo; Sarto, Gloria E; Key, Nigel S; Jacobs, David R; Kathiresan, Sekar; Bibbins-Domingo, Kirsten; Kshirsagar, Abhijit V; Wilson, James G; Reiner, Alexander P 2014. Association of sickle cell trait with chronic kidney disease and albuminuria in African Americans. JAMA, 312 20, 2115-25Hyacinth, Hyacinth I; Adekeye, Oluwatoyosi A; Yilgwan, Christopher S 2013. Malnutrition in Sickle Cell Anemia: Implications for Infection, Growth, and Maturation. Journal of social, behavioral and health sciences, 7 1, Adekeye, Oluwatoyosi A; Heiman, Harry J; Onyeabor, Onyekachi S; Hyacinth, Hyacinth I 2012. The new invincibles: HIV screening among older adults in the U.S. PloS one, 7 8, e43618Driss, Adel; Wilson, Nana O; Mason, Karlene; Hyacinth, Hyacinth I; Hibbert, Jacqueline M; Serjeant, Graham R; Stiles, Jonathan K 2012. Elevated IL-1? and CXCL10 serum levels occur in patients with homozygous sickle cell disease and a history of acute splenic sequestration. Disease markers, 32 5, 295-300Hyacinth, Hyacinth I; Adekeye, Oluwatoyosi A; Ibeh, Joy N; Osoba, Tolulope 2012. Cervical cancer and pap smear awareness and utilization of pap smear test among Federal civil servants in North Central Nigeria. PloS one, 7 10, e46583Hyacinth, Hyacinth I; Gee, Beatrice E; Adamkiewicz, Thomas V; Adams, Robert J; Kutlar, Abdullah; Stiles, Jonathan K; Hibbert, Jacqueline M 2012. Plasma BDNF and PDGF-AA levels are associated with high TCD velocity and stroke in children with sickle cell anemia. Cytokine, 60 1, 302-8Hyacinth, Hyacinth I; Oguche, Stephen; Yilgwan, Christopher S 2012. Summary Description of 24 Cases of Neonatal Malaria Seen at a Tertiary Health Center in Nigeria. Iranian journal of pediatrics, 22 1, 87-91Yilgwan, Christopher S; Utoo, Terkimbi B; Hyacinth, Hyacinth I 2012. Maternal characteristics influencing birth weight and infant weight gain in the first 6 weeks post-partum: A cross-sectional study of a post-natal clinic population. Nigerian medical journal : journal of the Nigeria Medical Association, 53 4, 200-5Bode-Thomas, F; Hyacinth, H I; Ogunkunle, O; Omotoso, A 2011. Myocardial ischaemia in sickle cell anaemia: evaluation using a new scoring system. Annals of tropical paediatrics, 31 1, 67-74Bode-Thomas, F; Hyacinth, Ih; Yilgwan, Cs 2010. Co-existence of Ventricular Septal Defect and Bronchial Asthma in Two Nigerian Children. Clinical medicine insights. Case reports, 3 , 5-8Hyacinth, H I; Gee, B E; Hibbert, J M 2010. The Role of Nutrition in Sickle Cell Disease. Nutrition and metabolic insights, 3 , 57-67Cahill, Christina R; Leach, Justin M; McClure, Leslie A; Irvin, Marguerite Ryan; Zakai, Neil A; Naik, Rakhi; Unverzagt, Frederick; Wadley, Virginia G; Hyacinth, Hyacinth I; Manly, Jennifer; Judd, Suzanne E; Winkler, Cheryl; Cushman, Mary . Sickle cell trait and risk of cognitive impairment in African-Americans: The REGARDS cohort. EClinicalMedicine, 11 , 27-33Douce, Daniel R; Soliman, Elsayed Z; Naik, Rakhi; Hyacinth, Hyacinth I; Cushman, Mary; Winkler, Cheryl A; Howard, George; Lange, Ethan M; Lange, Leslie A; Irvin, Marguerite R; Zakai, Neil A . Association of sickle cell trait with atrial fibrillation: The REGARDS cohort. Journal of electrocardiology, 55 , 1-5Yilgwan, Christopher S; Hyacinth, Hyacinth I; Oguche, Stephen . Factors associated with decreased survival from neonatal malaria infection in Jos, North Central Nigeria. Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria, 20 3, 349-54
Research InterestsBroadly, my research is focused on understanding the biological basis for disparity in stroke, cognitive impairment and dementia. Specifically, my research has and is examining the role of the sickle cell mutation and other genetic variants on the incidence and prevalence of cerebral macro and microvascular pathologies in individuals of African ancestry. In addition, we also seek to define the mechanisms by which genetic variation in populations, results in differential risk, susceptibility and/or pro...
Peer Reviewed Publications Gbotosho, Oluwabukola T; Gollamudi, Jahnavi; Hyacinth, Hyacinth I 2023. The Role of Inflammation in The Cellular and Molecular Mechanisms of Cardiopulmonary Complications of Sickle Cell Disease. Biomolecules, 13 2, Gbotosho, Oluwabukola T; Li, Wei; Joiner, Clinton H; Brown, Lou Ann S; Hyacinth, Hyacinth I 2023. The inflammatory profiles of pulmonary alveolar macrophages and alveolar type 2 cells in SCD. Experimental biology and medicine (Maywood, N.J.), , 15353702231157940Myserlis, Evangelos Pavlos; Georgakis, Marios K; Demel, Stacie L; Sekar, Padmini; Chung, Jaeyoon; Malik, Rainer; Hyacinth, Hyacinth I; Comeau, Mary E; Falcone, Guido J; Langefeld, Carl D; Rosand, Jonathan; Woo, Daniel; Anderson, Christopher D 2023. A Genomic Risk Score Identifies Individuals at High Risk for Intracerebral Hemorrhage. Stroke, 54 4, 973-982Sawyer, Russell P; Worrall, Bradford B; Howard, Virginia J; Crowe, Michael G; Howard, George; Hyacinth, Hyacinth I 2023. Methods of a Study to Assess the Contribution of Cerebral Small Vessel Disease and Dementia Risk Alleles to Racial Disparities in Vascular Cognitive Impairment and Dementia. Journal of the American Heart Association, , e030925Abi Rached, Noor Mary; Gbotosho, Oluwabukola T; Archer, David R; Jones, Jayre A; Sterling, Morgan S; Hyacinth, Hyacinth I 2022. Adhesion molecules and cerebral microvascular hemodynamic abnormalities in sickle cell disease. Frontiers in neurology, 13 , 976063Idris, Ibrahim M; Botchwey, Edward A; Hyacinth, Hyacinth I 2022. Sickle cell disease as an accelerated aging syndrome. Experimental biology and medicine (Maywood, N.J.), , 15353702211068522Mishra, Aniket; Malik, Rainer; Hachiya, Tsuyoshi; Jürgenson, Tuuli; Namba, Shinichi; Posner, Daniel C; Kamanu, Frederick K; Koido, Masaru; Le Grand, Quentin; Shi, Mingyang; He, Yunye; Georgakis, Marios K; Caro, Ilana; Krebs, Kristi; Liaw, Yi-Ching; Vaura, Felix C; Lin, Kuang; Winsvold, Bendik Slagsvold; Srinivasasainagendra, Vinodh; Parodi, Livia; Bae, Hee-Joon; Chauhan, Ganesh; Chong, Michael R; Tomppo, Liisa; Akinyemi, Rufus; Roshchupkin, Gennady V; Habib, Naomi; Jee, Yon Ho; Thomassen, Jesper Qvist; Abedi, Vida; Cárcel-Márquez, Jara; Nygaard, Marianne; Leonard, Hampton L; Yang, Chaojie; Yonova-Doing, Ekaterina; Knol, Maria J; Lewis, Adam J; Judy, Renae L; Ago, Tetsuro; Amouyel, Philippe; Armstrong, Nicole D; Bakker, Mark K; Bartz, Traci M; Bennett, David A; Bis, Joshua C; Bordes, Constance; Børte, Sigrid; Cain, Anael; Ridker, Paul M; Cho, Kelly; Chen, Zhengming; Cruchaga, Carlos; Cole, John W; de Jager, Phil L; de Cid, Rafael; Endres, Matthias; Ferreira, Leslie E; Geerlings, Mirjam I; Gasca, Natalie C; Gudnason, Vilmundur; Hata, Jun; He, Jing; Heath, Alicia K; Ho, Yuk-Lam; Havulinna, Aki S; Hopewell, Jemma C; Hyacinth, Hyacinth I; Inouye, Michael; Jacob, Mina A; Jeon, Christina E; Jern, Christina; Kamouchi, Masahiro; Keene, Keith L; Kitazono, Takanari; Kittner, Steven J; Konuma, Takahiro; Kumar, Amit; Lacaze, Paul; Launer, Lenore J; Lee, Keon-Joo; Lepik, Kaido; Li, Jiang; Li, Liming; Manichaikul, Ani; Markus, Hugh S; Marston, Nicholas A; Meitinger, Thomas; Mitchell, Braxton D; Montellano, Felipe A; Morisaki, Takayuki; Mosley, Thomas H; Nalls, Mike A; Nordestgaard, Børge G; O'Donnell, Martin J; Okada, Yukinori; Onland-Moret, N Charlotte; Ovbiagele, Bruce; Peters, Annette; Psaty, Bruce M; Rich, Stephen S; Rosand, Jonathan; Sabatine, Marc S; Sacco, Ralph L; Saleheen, Danish; Sandset, Else Charlotte; Salomaa, Veikko; Sargurupremraj, Muralidharan; Sasaki, Makoto; Satizabal, Claudia L; Schmidt, Carsten O; Shimizu, Atsushi; Smith, Nicholas L; Sloane, Kelly L; Sutoh, Yoichi; Sun, Yan V; Tanno, Kozo; Tiedt, Steffen; Tatlisumak, Turgut; Torres-Aguila, Nuria P; Tiwari, Hemant K; Trégouët, David-Alexandre; Trompet, Stella; Tuladhar, Anil Man; Tybjærg-Hansen, Anne; van Vugt, Marion; Vibo, Riina; Verma, Shefali S; Wiggins, Kerri L; Wennberg, Patrik; Woo, Daniel; Wilson, Peter W F; Xu, Huichun; Yang, Qiong; Yoon, Kyungheon ; Millwood, Iona Y; Gieger, Christian; Ninomiya, Toshiharu; Grabe, Hans J; Jukema, J Wouter; Rissanen, Ina L; Strbian, Daniel; Kim, Young Jin; Chen, Pei-Hsin; Mayerhofer, Ernst; Howson, Joanna M M; Irvin, Marguerite R; Adams, Hieab; Wassertheil-Smoller, Sylvia; Christensen, Kaare; Ikram, Mohammad A; Rundek, Tatjana; Worrall, Bradford B; Lathrop, G Mark; Riaz, Moeen; Simonsick, Eleanor M; Kõrv, Janika; França, Paulo H C; Zand, Ramin; Prasad, Kameshwar; Frikke-Schmidt, Ruth; de Leeuw, Frank-Erik; Liman, Thomas; Haeusler, Karl Georg; Ruigrok, Ynte M; Heuschmann, Peter Ulrich; Longstreth, W T; Jung, Keum Ji; Bastarache, Lisa; Paré, Guillaume; Damrauer, Scott M; Chasman, Daniel I; Rotter, Jerome I; Anderson, Christopher D; Zwart, John-Anker; Niiranen, Teemu J; Fornage, Myriam; Liaw, Yung-Po; Seshadri, Sudha; Fernández-Cadenas, Israel; Walters, Robin G; Ruff, Christian T; Owolabi, Mayowa O; Huffman, Jennifer E; Milani, Lili; Kamatani, Yoichiro; Dichgans, Martin; Debette, Stephanie 2022. Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries. Nature, 612 7938, E7Mishra, Aniket; Malik, Rainer; Hachiya, Tsuyoshi; Jürgenson, Tuuli; Namba, Shinichi; Posner, Daniel C; Kamanu, Frederick K; Koido, Masaru; Le Grand, Quentin; Shi, Mingyang; He, Yunye; Georgakis, Marios K; Caro, Ilana; Krebs, Kristi; Liaw, Yi-Ching; Vaura, Felix C; Lin, Kuang; Winsvold, Bendik Slagsvold; Srinivasasainagendra, Vinodh; Parodi, Livia; Bae, Hee-Joon; Chauhan, Ganesh; Chong, Michael R; Tomppo, Liisa; Akinyemi, Rufus; Roshchupkin, Gennady V; Habib, Naomi; Jee, Yon Ho; Thomassen, Jesper Qvist; Abedi, Vida; Cárcel-Márquez, Jara; Nygaard, Marianne; Leonard, Hampton L; Yang, Chaojie; Yonova-Doing, Ekaterina; Knol, Maria J; Lewis, Adam J; Judy, Renae L; Ago, Tetsuro; Amouyel, Philippe; Armstrong, Nicole D; Bakker, Mark K; Bartz, Traci M; Bennett, David A; Bis, Joshua C; Bordes, Constance; Børte, Sigrid; Cain, Anael; Ridker, Paul M; Cho, Kelly; Chen, Zhengming; Cruchaga, Carlos; Cole, John W; de Jager, Phil L; de Cid, Rafael; Endres, Matthias; Ferreira, Leslie E; Geerlings, Mirjam I; Gasca, Natalie C; Gudnason, Vilmundur; Hata, Jun; He, Jing; Heath, Alicia K; Ho, Yuk-Lam; Havulinna, Aki S; Hopewell, Jemma C; Hyacinth, Hyacinth I; Inouye, Michael; Jacob, Mina A; Jeon, Christina E; Jern, Christina; Kamouchi, Masahiro; Keene, Keith L; Kitazono, Takanari; Kittner, Steven J; Konuma, Takahiro; Kumar, Amit; Lacaze, Paul; Launer, Lenore J; Lee, Keon-Joo; Lepik, Kaido; Li, Jiang; Li, Liming; Manichaikul, Ani; Markus, Hugh S; Marston, Nicholas A; Meitinger, Thomas; Mitchell, Braxton D; Montellano, Felipe A; Morisaki, Takayuki; Mosley, Thomas H; Nalls, Mike A; Nordestgaard, Børge G; O'Donnell, Martin J; Okada, Yukinori; Onland-Moret, N Charlotte; Ovbiagele, Bruce; Peters, Annette; Psaty, Bruce M; Rich, Stephen S; Rosand, Jonathan; Sabatine, Marc S; Sacco, Ralph L; Saleheen, Danish; Sandset, Else Charlotte; Salomaa, Veikko; Sargurupremraj, Muralidharan; Sasaki, Makoto; Satizabal, Claudia L; Schmidt, Carsten O; Shimizu, Atsushi; Smith, Nicholas L; Sloane, Kelly L; Sutoh, Yoichi; Sun, Yan V; Tanno, Kozo; Tiedt, Steffen; Tatlisumak, Turgut; Torres-Aguila, Nuria P; Tiwari, Hemant K; Trégouët, David-Alexandre; Trompet, Stella; Tuladhar, Anil Man; Tybjærg-Hansen, Anne; van Vugt, Marion; Vibo, Riina; Verma, Shefali S; Wiggins, Kerri L; Wennberg, Patrik; Woo, Daniel; Wilson, Peter W F; Xu, Huichun; Yang, Qiong; Yoon, Kyungheon ; Millwood, Iona Y; Gieger, Christian; Ninomiya, Toshiharu; Grabe, Hans J; Jukema, J Wouter; Rissanen, Ina L; Strbian, Daniel; Kim, Young Jin; Chen, Pei-Hsin; Mayerhofer, Ernst; Howson, Joanna M M; Irvin, Marguerite R; Adams, Hieab; Wassertheil-Smoller, Sylvia; Christensen, Kaare; Ikram, Mohammad A; Rundek, Tatjana; Worrall, Bradford B; Lathrop, G Mark; Riaz, Moeen; Simonsick, Eleanor M; Kõrv, Janika; França, Paulo H C; Zand, Ramin; Prasad, Kameshwar; Frikke-Schmidt, Ruth; de Leeuw, Frank-Erik; Liman, Thomas; Haeusler, Karl Georg; Ruigrok, Ynte M; Heuschmann, Peter Ulrich; Longstreth, W T; Jung, Keum Ji; Bastarache, Lisa; Paré, Guillaume; Damrauer, Scott M; Chasman, Daniel I; Rotter, Jerome I; Anderson, Christopher D; Zwart, John-Anker; Niiranen, Teemu J; Fornage, Myriam; Liaw, Yung-Po; Seshadri, Sudha; Fernández-Cadenas, Israel; Walters, Robin G; Ruff, Christian T; Owolabi, Mayowa O; Huffman, Jennifer E; Milani, Lili; Kamatani, Yoichiro; Dichgans, Martin; Debette, Stephanie 2022. Stroke genetics informs drug discovery and risk prediction across ancestries. Nature, 611 7934, 115-123Muratoglu, Selen C; Charette, Marc F; Galis, Zorina S; Greenstein, Adam S; Daugherty, Alan; Joutel, Anne; Kozel, Beth A; Wilcock, Donna M; Collins, Emily C; Sorond, Farzaneh A; Howell, Gareth R; Hyacinth, Hyacinth I; Lloyd, Kent K C; Stenmark, Kurt R; Boehm, Manfred; Kahn, Mark L; Corriveau, Roderick; Wells, Sara; Bussey, Timothy J; Sukoff Rizzo, Stacey J; Iruela-Arispe, M Luisa 2022. Perspectives on Cognitive Phenotypes and Models of Vascular Disease. Arteriosclerosis, thrombosis, and vascular biology, 42 7, 831-838Sawyer, Russell P; Pun, Sirjana; Karkoska, Kristine A; Clendinen, Cherita A; DeBaun, Michael R; Gutmark, Ephraim; Barrile, Riccardo; Hyacinth, Hyacinth I 2022. Effect of Blood Transfusion on Cerebral Hemodynamics and Vascular Topology Described by Computational Fluid Dynamics in Sickle Cell Disease Patients. Brain sciences, 12 10, Hyacinth, Hyacinth I; Franceschini, Nora; Seals, Samantha R; Irvin, Marguerite R; Chaudhary, Ninad; Naik, Rakhi P; Alonso, Alvaro; Carty, Cara L; Burke, Gregory L; Zakai, Neil A; Winkler, Cheryl A; David, Victor A; Kopp, Jeffrey B; Judd, Suzanne E; Adams, Robert J; Gee, Beatrice E; Longstreth, W T; Egede, Leonard; Lackland, Daniel T; Greenberg, Charles S; Taylor, Herman; Manson, JoAnn E; Key, Nigel S; Derebail, Vimal K; Kshirsagar, Abhijit V; Folsom, Aaron R; Konety, Suma H; Howard, Virginia; Allison, Matthew; Wilson, James G; Correa, Adolfo; Zhi, Degui; Arnett, Donna K; Howard, George; Reiner, Alexander P; Cushman, Mary; Safford, Monika M 2021. Association of Sickle Cell Trait With Incidence of Coronary Heart Disease Among African American Individuals. JAMA network open, 4 1, e2030435Nartey, Eunice Berko; Spector, Jonathan; Adu-Afarwuah, Seth; Jones, Catherine L; Jackson, Alan; Ohemeng, Agartha; Shah, Rajiv; Koryo-Dabrah, Alice; Kuma, Amma Benneh-Akwasi; Hyacinth, Hyacinth I; Steiner-Asiedu, Matilda 2021. Nutritional perspectives on sickle cell disease in Africa: a systematic review. BMC nutrition, 7 1, 9Prapiadou, Savvina; Demel, Stacie L; Hyacinth, Hyacinth I 2021. Genetic and Genomic Epidemiology of Stroke in People of African Ancestry. Genes, 12 11, Chen, Nemin; Caruso, Christina; Alonso, Alvaro; Derebail, Vimal K; Kshirsagar, Abhijit V; Sharrett, A Richey; Key, Nigel S; Gottesman, Rebecca F; Grove, Megan L; Bressler, Jan; Boerwinkle, Eric; Windham, B Gwen; Mosley, Thomas H; Hyacinth, Hyacinth I 2020. Corrigendum to 'Association of sickle cell trait with measures of cognitive function and dementia in African Americans' eNeurologicalSci, Vol. 16 (2019), 100,201. eNeurologicalSci, 21 , 100281Hardy, Raven A; Rached, Noor Abi; Jones, Jayre A; Archer, David R; Hyacinth, Hyacinth I 2020. Role of age and neuroinflammation in the mechanism of cognitive deficits in sickle cell disease. Experimental biology and medicine (Maywood, N.J.), , 1535370220958011Holshouser, Steven; Cafiero, Rebecca; Robinson, Mayra; Kirkpatrick, Joy; Casero, Robert A; Hyacinth, Hyacinth I; Woster, Patrick M 2020. Epigenetic Reexpression of Hemoglobin F Using Reversible LSD1 Inhibitors: Potential Therapies for Sickle Cell Disease. ACS omega, 5 24, 14750-14758Hyacinth, Hyacinth I; Idris, Ibrahim M 2020. Cognitive deficit in sickle cell disease: Is hydroxyurea part of the story? British journal of haematology, 189 6, 1014-1015Keene, Keith L; Hyacinth, Hyacinth I; Bis, Joshua C; Kittner, Steven J; Mitchell, Braxton D; Cheng, Yu-Ching; Pare, Guillaume; Chong, Michael; O'Donnell, Martin; Meschia, James F; Chen, Wei-Min; Sale, Michèle M; Rich, Stephen S; Nalls, Mike A; Zonderman, Alan B; Evans, Michele K; Wilson, James G; Correa, Adolfo; Markus, Hugh S; Traylor, Matthew; Lewis, Cathryn M; Carty, Cara L; Reiner, Alexander; Haessler, Jeff; Langefeld, Carl D; Gottesman, Rebecca; Mosley, Thomas H; Woo, Daniel; Yaffe, Kristine; Liu, YongMei; Longstreth, William T; Psaty, Bruce M; Kooperberg, Charles; Lange, Leslie A; Sacco, Ralph; Rundek, Tatjana; Lee, Jin-Moo; Cruchaga, Carlos; Furie, Karen L; Arnett, Donna K; Benavente, Oscar R; Grewal, Raji P; Peddareddygari, Leema Reddy; Dichgans, Martin; Malik, Rainer; Worrall, Bradford B; Fornage, Myriam 2020. Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke. Stroke, 51 8, 2454-2463Chauhan, Ganesh; Adams, Hieab H H; Satizabal, Claudia L; Bis, Joshua C; Teumer, Alexander; Sargurupremraj, Muralidharan; Hofer, Edith; Trompet, Stella; Hilal, Saima; Smith, Albert Vernon; Jian, Xueqiu; Malik, Rainer; Traylor, Matthew; Pulit, Sara L; Amouyel, Philippe; Mazoyer, Bernard; Zhu, Yi-Cheng; Kaffashian, Sara; Schilling, Sabrina; Beecham, Gary W; Montine, Thomas J; Schellenberg, Gerard D; Kjartansson, Olafur; Guðnason, Vilmundur; Knopman, David S; Griswold, Michael E; Windham, B Gwen; Gottesman, Rebecca F; Mosley, Thomas H; Schmidt, Reinhold; Saba, Yasaman; Schmidt, Helena; Takeuchi, Fumihiko; Yamaguchi, Shuhei; Nabika, Toru; Kato, Norihiro; Rajan, Kumar B; Aggarwal, Neelum T; De Jager, Philip L; Evans, Denis A; Psaty, Bruce M; Rotter, Jerome I; Rice, Kenneth; Lopez, Oscar L; Liao, Jiemin; Chen, Christopher; Cheng, Ching-Yu; Wong, Tien Y; Ikram, Mohammad K; van der Lee, Sven J; Amin, Najaf; Chouraki, Vincent; DeStefano, Anita L; Aparicio, Hugo J; Romero, Jose R; Maillard, Pauline; DeCarli, Charles; Wardlaw, Joanna M; Hernández, Maria Del C Valdés; Luciano, Michelle; Liewald, David; Deary, Ian J; Starr, John M; Bastin, Mark E; Muñoz Maniega, Susana; Slagboom, P Eline; Beekman, Marian; Deelen, Joris; Uh, Hae-Won; Lemmens, Robin; Brodaty, Henry; Wright, Margaret J; Ames, David; Boncoraglio, Giorgio B; Hopewell, Jemma C; Beecham, Ashley H; Blanton, Susan H; Wright, Clinton B; Sacco, Ralph L; Wen, Wei; Thalamuthu, Anbupalam; Armstrong, Nicola J; Chong, Elizabeth; Schofield, Peter R; Kwok, John B; van der Grond, Jeroen; Stott, David J; Ford, Ian; Jukema, J Wouter; Vernooij, Meike W; Hofman, Albert; Uitterlinden, André G; van der Lugt, Aad; Wittfeld, Katharina; Grabe, Hans J; Hosten, Norbert; von Sarnowski, Bettina; Völker, Uwe; Levi, Christopher; Jimenez-Conde, Jordi; Sharma, Pankaj; Sudlow, Cathie L M; Rosand, Jonathan; Woo, Daniel; Cole, John W; Meschia, James F; Slowik, Agnieszka; Thijs, Vincent; Lindgren, Arne; Melander, Olle; Grewal, Raji P; Rundek, Tatjana; Rexrode, Kathy; Rothwell, Peter M; Arnett, Donna K; Jern, Christina; Johnson, Julie A; Benavente, Oscar R; Wasssertheil-Smoller, Sylvia; Lee, Jin-Moo; Wong, Quenna; Mitchell, Braxton D; Rich, Stephen S; McArdle, Patrick F; Geerlings, Mirjam I; van der Graaf, Yolanda; de Bakker, Paul I W; Asselbergs, Folkert W; Srikanth, Velandai; Thomson, Russell; McWhirter, Rebekah; Moran, Chris; Callisaya, Michele; Phan, Thanh; Rutten-Jacobs, Loes C A; Bevan, Steve; Tzourio, Christophe; Mather, Karen A; Sachdev, Perminder S; van Duijn, Cornelia M; Worrall, Bradford B; Dichgans, Martin; Kittner, Steven J; Markus, Hugh S; Ikram, Mohammad A; Fornage, Myriam; Launer, Lenore J; Seshadri, Sudha; Longstreth, W T; Debette, Stéphanie 2019. Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting. Neurology, , Chen, Nemin; Caruso, Christina; Alonso, Alvaro; Derebail, Vimal K; Kshirsagar, Abhijit V; Sharrett, A Richey; Key, Nigel S; Gottesman, Rebecca F; Grove, Megan L; Bressler, Jan; Boerwinkle, Eric; Windham, B Gwen; Mosley, Thomas H; Hyacinth, Hyacinth I 2019. Association of sickle cell trait with measures of cognitive function and dementia in African Americans. eNeurologicalSci, 16 , 100201Hyacinth, Hyacinth I; Sugihara, Courtney L; Spencer, Thomas L; Archer, David R; Shih, Andy Y 2019. Higher prevalence of spontaneous cerebral vasculopathy and cerebral infarcts in a mouse model of sickle cell disease. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 39 2, 342-351Larsson, Susanna C; Traylor, Matthew; Burgess, Stephen; Boncoraglio, Giorgio B; Jern, Christina; Michaëlsson, Karl; Markus, Hugh S 2019. Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study. Neurology, 92 9, e944-e950Malik, Rainer; Chauhan, Ganesh; Traylor, Matthew; Sargurupremraj, Muralidharan; Okada, Yukinori; Mishra, Aniket; Rutten-Jacobs, Loes; Giese, Anne-Katrin; van der Laan, Sander W; Gretarsdottir, Solveig; Anderson, Christopher D; Chong, Michael; Adams, Hieab H H; Ago, Tetsuro; Almgren, Peter; Amouyel, Philippe; Ay, Hakan; Bartz, Traci M; Benavente, Oscar R; Bevan, Steve; Boncoraglio, Giorgio B; Brown, Robert D; Butterworth, Adam S; Carrera, Caty; Carty, Cara L; Chasman, Daniel I; Chen, Wei-Min; Cole, John W; Correa, Adolfo; Cotlarciuc, Ioana; Cruchaga, Carlos; Danesh, John; de Bakker, Paul I W; DeStefano, Anita L; den Hoed, Marcel; Duan, Qing; Engelter, Stefan T; Falcone, Guido J; Gottesman, Rebecca F; Grewal, Raji P; Gudnason, Vilmundur; Gustafsson, Stefan; Haessler, Jeffrey; Harris, Tamara B; Hassan, Ahamad; Havulinna, Aki S; Heckbert, Susan R; Holliday, Elizabeth G; Howard, George; Hsu, Fang-Chi; Hyacinth, Hyacinth I; Ikram, M Arfan; Ingelsson, Erik; Irvin, Marguerite R; Jian, Xueqiu; Jiménez-Conde, Jordi; Johnson, Julie A; Jukema, J Wouter; Kanai, Masahiro; Keene, Keith L; Kissela, Brett M; Kleindorfer, Dawn O; Kooperberg, Charles; Kubo, Michiaki; Lange, Leslie A; Langefeld, Carl D; Langenberg, Claudia; Launer, Lenore J; Lee, Jin-Moo; Lemmens, Robin; Leys, Didier; Lewis, Cathryn M; Lin, Wei-Yu; Lindgren, Arne G; Lorentzen, Erik; Magnusson, Patrik K; Maguire, Jane; Manichaikul, Ani; McArdle, Patrick F; Meschia, James F; Mitchell, Braxton D; Mosley, Thomas H; Nalls, Michael A; Ninomiya, Toshiharu; O'Donnell, Martin J; Psaty, Bruce M; Pulit, Sara L; Rannikmäe, Kristiina; Reiner, Alexander P; Rexrode, Kathryn M; Rice, Kenneth; Rich, Stephen S; Ridker, Paul M; Rost, Natalia S; Rothwell, Peter M; Rotter, Jerome I; Rundek, Tatjana; Sacco, Ralph L; Sakaue, Saori; Sale, Michele M; Salomaa, Veikko; Sapkota, Bishwa R; Schmidt, Reinhold; Schmidt, Carsten O; Schminke, Ulf; Sharma, Pankaj; Slowik, Agnieszka; Sudlow, Cathie L M; Tanislav, Christian; Tatlisumak, Turgut; Taylor, Kent D; Thijs, Vincent N S; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Tiedt, Steffen; Trompet, Stella; Tzourio, Christophe; van Duijn, Cornelia M; Walters, Matthew; Wareham, Nicholas J; Wassertheil-Smoller, Sylvia; Wilson, James G; Wiggins, Kerri L; Yang, Qiong; Yusuf, Salim ; Bis, Joshua C; Pastinen, Tomi; Ruusalepp, Arno; Schadt, Eric E; Koplev, Simon; Björkegren, Johan L M; Codoni, Veronica; Civelek, Mete; Smith, Nicholas L; Trégouët, David A; Christophersen, Ingrid E; Roselli, Carolina; Lubitz, Steven A; Ellinor, Patrick T; Tai, E Shyong; Kooner, Jaspal S; Kato, Norihiro; He, Jiang; van der Harst, Pim; Elliott, Paul; Chambers, John C; Takeuchi, Fumihiko; Johnson, Andrew D ; Sanghera, Dharambir K; Melander, Olle; Jern, Christina; Strbian, Daniel; Fernandez-Cadenas, Israel; Longstreth, W T; Rolfs, Arndt; Hata, Jun; Woo, Daniel; Rosand, Jonathan; Pare, Guillaume; Hopewell, Jemma C; Saleheen, Danish; Stefansson, Kari; Worrall, Bradford B; Kittner, Steven J; Seshadri, Sudha; Fornage, Myriam; Markus, Hugh S; Howson, Joanna M M; Kamatani, Yoichiro; Debette, Stephanie; Dichgans, Martin 2019. Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. 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