Publications

Peer-reviewed manuscripts

1. Kelsey KR and Reyes, TM (in press) High fat diet consumption restricted to adolescence has minimal effects on adult executive function that vary by sex, Nutritional Neuroscience
2. Smith BL, Laaker CJ, Lloyd KR, Hiltz AR, Reyes TM. (2020) Adolescent microglia play a role in executive function in male mice exposed to perinatal high fat diet. Brain Behav Immun. 84:80-89
3. Makinson R, Lloyd K, Grissom N, Reyes TM. (2019) Exposure to in utero inflammation increases locomotor activity, alters cognitive performance and drives vulnerability to cognitive performance deficits after acute immune activation. Brain Behav Immun. (18)30454-9
4. Kumar VJ, Grissom NM, McKee SE, Schoch H, Bowman N, Havekes R, Kumar M, Pickup S, Poptani H, Reyes TM, Hawrylycz M, Abel T, Nickl-Jockschat T. (2018) Linking spatial gene expression patterns to sex-specific brain structural changes on a mouse model of 16p11.2 hemideletion. Translational Psychiatry. 8(1):109
5. Huo X, Reyes TM, Heijnen CJ, Kavelaars A (2018) Cisplatin treatment induces attention deficits and impairs synaptic integrity in the prefrontal cortex in mice. Sci Rep. 8(1):17400
6. Grissom NM, McKee SE, Schoch H, Bowman N, Havekes R, O'Brien WT, Mahrt E, Siegel S, Commons K, Portfors C, Nickl-Jockschat T, Reyes TM, Abel T. (2018) Male-specific deficits in natural reward learning in a mouse model of neurodevelopmental disorders. Mol Psychiatry. 23(3):544-555. doi: 10.1038/mp.2017.184
7. Lloyd KR, Yaghoubi SK, Makinson RA, McKee SE, Reyes TM. (2018) Housing and testing in mixed-sex rooms increases motivation and accuracy during operant testing in both male and female mice.  Neurobiol Learn Mem.  150:20-24. doi: 10.1016/j.nlm.2018.01.005
8. McKee SE, Zhang S, Chen L, Rabinowitz JD, Reyes TM. (2018) Perinatal high fat diet and early life methyl donor supplementation alter one carbon metabolism and DNA methylation in the brain. J Neurochem. 145(5):362-373. doi: 10.1111/jnc.14319.
9. Kumar VJ, Grissom NM, McKee SE, Schoch H, Bowman N, Havekes R, Kumar M, Pickup S, Poptani H, Reyes TM, Hawrylycz M, Abel T, Nickl-Jockschat T. (2018) Linking spatial gene expression patterns to sex-specific brain structural changes on a mouse model of 16p11.2 hemideletion.  Transl Psychiatry 8(1):109. doi: 10.1038/s41398-018-0157-z.
10. McKee SE, Grissom NM, Herdt CT, Reyes TM. (2017) Methyl donor supplementation alters cognitive performance and motivation in female offspring from high-fat diet-fed dams. FASEB J. 31(6):2352-2363. doi: 10.1096/fj.201601172R
11. Makinson R, Lloyd K, Rayasam A, McKee S, Brown A, Barila G, Grissom N, George R, Marini M, Fabry Z, Elovitz M, Reyes TM. (2017) Intrauterine inflammation induces sex-specific effects on neuroinflammation, white matter, and behavior. Brain Behav Immun.  66:277-288. doi: 10.1016/j.bbi.2017.07.016
12. Grissom NM, George R, Reyes TM (2016) Suboptimal nutrition in early life affects the inflammatory gene expression profile and behavioral responses to stressors. Brain Behav Immun. 63:115-126. doi: 10.1016/j.bbi.2016.10.013
13. Thanos PK, Zhuo J, Robison L, Kim R, Ananth M, Choai I, Grunseich A, Grissom NM, George R, Delis F, Reyes TM Suboptimal maternal diets alter mu opioid receptor and dopamine type 1 receptor binding but exert no effect on dopamine transporters in the offspring brain. (2018) Int J Dev Neurosci. 64:21-28
14. Carlin JL, Grissom N, Ying Z, Gomez-Pinilla F, Reyes TM. (2016) Voluntary exercise blocks Western diet-induced gene expression of the chemokines CXCL10 and CCL2 in the prefrontal cortex. Brain Behav Immun. Nov;58:82-90
15. J. L. Carlin, S. E. McKee, T. Hill-Smith, N. M. Grissom, R. George, I.Lucki and T. M Reyes (2016) Removal of high fat diet after chronic exposure drives binge behavior and dopaminergic dysregulation in female mice. Neuroscience 326:170-9
16. Grissom NM, George R, Reyes TM. (2015) The hypothalamic transcriptional response to stress is severely impaired in offspring exposed to adverse nutrition during gestation.  Neuroscience. 2015 Jul 26. pii: S0306-4522(15)00636-3. doi: 10.1016/j.neuroscience.2015.07.022.
17. N. M. Grissom, C. T. Herdt, J. Desilets, J. Lidsky-Everson, T. M. Reyes (2014), Dissociable deficits of executive function caused by gestational adversity are linked to specific transcriptional changes in the prefrontal cortex.  Neuropsychopharmacology, doi: 10.1038/npp.2014.313
18. N. M. Grissom, R. Lyde, L. Christ, I. E. Sasson, J. Carlin, A. P. Vitins, R. A. Simmons and T. M. Reyes (2014) Obesity at conception programs the opioid system in the offspring brain. Neuropsychopharmacology, 39(4):801-10
19. J. Carlin, R. George, and Reyes TM. (2013) Methyl donor supplementation blocks the adverse effects of maternal high fat diet on offspring physiology. PLOS One, May 2;8(5):e63549
20. J. Carlin, T. E. Hill-Smith, I. Lucki and T. M. Reyes (2013) Reversal of dopamine system dysfunction in response to high fat diet. Obesity, 21(12):2513-21
21. Grissom, N and Reyes, TM. (2013) Gestational overgrowth and undergrowth affect neurodevelopment: similarities and differences from behavior to epigenetics. International Journal of Developmental Neuroscience. 31(6):406-14
22. G. K. Paschos, S. Ibrahim, W-L. Song, T Kunieda, G Grant, T M. Reyes, C A. Bradfield, C H. Vaughan, M Eiden, M Masoodi, J L. Griffin, F Wang, J A. Lawson and G. A. FitzGerald (2012) Obesity in mice with adipocyte-specific deletion of clock component Bmal1. Nature Medicine. 18(12):1768-77
23. Vucetic Z, Carlin J, Totoki K, Reyes TM. (2012) Epigenetic dysregulation of the dopamine system in diet-induced obesity.  J Neurochem. 120(6):891-8
24. K. W. Whitaker, K. Totoki, and T. M. Reyes (2012) Metabolic adaptations to early life protein restriction differ by offspring sex and postweaning diet in the mouse. Nutrition, Metabolism and Cardiovascular Diseases 22(12):1067-74
25. Z. Vucetic, J. Kimmel and T. M. Reyes (2011) Chronic high fat diet drives postnatal epigenetic regulation of µ-opioid receptor in the brain. Neuropsychopharmacology, 36: 1199-1206.
26. Z. Vucetic, J. Kimmel, K. Totoki, E. Hollenbeck and T. M. Reyes (2010) Maternal high fat diet alters methylation and gene expression of dopamine and opioid related genes. Endocrinology. 151(10): 4756-64