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Pharmacology, Physiology, & Neurobiology
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Seminar Archives

Departmental Seminar Archives

2024

Date	Name	Description
January 9	Barbara Nikolajczyk, PhD University of Kentucky College of Medicine	Inflammation in human obesity and type 2 diabetes
February 13	Pilar Alcaide, PhD Tufts University School of Medicine	T cells and adverse cardiac remodeling
March 12	Rong Tian, PhD University of Washington at Seattle	Mitochondrial function in heart failure: HFrEF vs. HFpEF
April 9	Baljit Khakh, PhD University of California at Los Angeles	Astrocyte diversity in neural circuits: identity, form, and function
May 21	Kranias Symposium on Early Career Mentorship Mark Mercola, PhD Department of Medicine and Cardiovascular Institute Stanford University School of Medicine	iPSC-based modeling of heart disease for drug discovery
June 11	PSP Trainees' Research Day Vittorio Gallo, PhD Chief Research Officer, Children's National Research Institute Director, District of Columbia Intellectual and Developmental Disabilities Research Center (DC-IDDRC) Associate Dean, Child Health Research	Cellular and molecular mechanisms of injury and recovery in the neonatal brain
September 4	David Dadosky Molecular, Cellular, and Biochemical Pharmacology Luis Tron Esqueda Systems Biology and Physiology	Examining the role of glucocorticoid signaling in the behavioral and synaptic effects of tryptamines The role endothelial TFEB plays in the blood brain barrier and Alzheimer's disease
October 2	Alyshia Davis Systems Biology and Physiology Corbin Azucenas Systems Biology and Physiology	Adolescent cancer and chemotherapy induce sex specific alterations to immune-related gene expression Inducible, erythroid-specific knockout of codanin-1 replicates congenital dyserythropoietic anemia type-Ia
November 6	Alexander Kuhn Systems Biology and Physiology Drew Howard Molecular, Cellular, and Biochemical Pharmacology	title TBD title TBD
December 4	Lindsay Helock Molecular, Cellular, and Biochemical Pharmacology Olukunle Akinborewa Systems Biology and Physiology	title TBD title TBD

2023

Date	Name	Description
January 10	David Morilak, PhD University of Texas Health Science Center	Extinction learning in rats as a model of cognitive-behavioral therapy for stress-related psychiatric disorders
February 7	Steven Jones, PhD University of Louisville	Metabolic regulation of fibroblasts and inflammation in the heart
March 14	Jeff Saucerman, PhD University of Virginia	Genes, drugs, and networks for cardiac remodeling
April 11	Elizabeta Nemeth, PhD David Geffen School of Medicine at the University of California at Los Angeles	Iron physiology and pathology in pregnancy
May 17	Kranias Symposium on Early Career Mentorship Manolis Kellis, PhD Professor, MIT Computer Science and Artificial Intelligence Lab Member, Broad Institute of MIT and Harvard Massachusetts Institute of Technology	From genomics to therapeutics: Single-cell dissection and manipulation of disease circuitry
June 13	PSP Trainees' Research Day Ira Goldberg, MD Clarissa and Edgar Bronfman, Jr. Professor of Endocrinology Director, Division of Endocrinology, Diabetes, and Metabolism NYU Grossman School of Medicine, NYU Langone Health	Postprandial lipemia, chylomicrons and CVD
September 12	Thomas Hund, PhD The Ohio State University	Novel pathways for regulation of cardiac electrical and mechanical function
November 14	Paul Fox, PhD Cleveland Clinic	EPRS1 and neurological disease
December 12	Jeffrey Tasker, PhD Tulane University	Neuromodulatory control of basolateral amygdala inhibitory circuits controlling fear memory and dysregulation by traumatic stress

2022

Date	Name	Description
February 8	Stacey Schutte, PhD University of Cincinnati	The mechanosensitivity of uterine fibroids
February 15	Michael Tranter, PhD University of Cincinnati College of Medicine	Adipose tissue as a direct endocrine mediator of myocardial physiology
March 8	Xenia Davis Molecular, Cellular, and Biochemical Pharmacology Dakota Zinani Molecular, Cellular, and Biochemical Pharmacology	The role of adipocyte-specific signal transducer and activator of transcription 3 during sepsis The effect of antagonists on drug-induced lever-pressing behavior during unloading
March 29	Darshini Desai Molecular, Cellular, and Biochemical Pharmacology Natalie Norman Systems Biology and Physiology	Modelling cardiac dysfunction associated with a polymorphic D389V variant in MYBPC3 using hiPSC-derived cardiac organoids An exercise-driven, insulin-independent glucose uptake pathway in contracting skeletal muscle
April 12	Christopher Parker Systems Biology and Physiology Faiz Rizvi Systems Biology and Physiology	Mathematical modeling of the HPA axis in MDD maxATAC: genome-scale transcription-factor binding prediction from ATAC-seq with deep neural networks
April 26	Laurence Coutillier, PhD The Ohio State University	Prefrontal interneurons and female vulnerability to stress
May 3	Alaa Alghamdi Molecular, Cellular, and Biochemical Pharmacology Kairavee Thakkar Systems Biology and Physiology	Association between tacrolimus and CYP3A5 genotype in pediatric kidney transplant De novo patient subtype and phenotype discovery from single-cell data using UDON
May 17	Kranias Symposium on Early Career Mentorship Maria Kontaridis, PhD Gordon K. Moe Professor and Chair in Biomedical Research and Translational Medicine, Director of Research, Masonic Medical Research Institute	The road to scientific success: from phosphatases to leadership
October 14	Arnold Schwartz Cardiovascular Clinical Pharmacology Lecture Walter Koch, PhD William Wikoff Smith Endowed Chair in Cardiovascular Medicine, Chair and Professor, Department of Cardiovascular Sciences, Director, Center for Translational Medicine, Lewis Katz School of Medicine, Temple University	GRK2 and GRK5 in the heart: a tail of 2 kinases
November 8	Konstantinos Stellos, MD Heidelberg University	RNA modifications in cardiovascular health and disease
December 13	Kathryn Lenz, PhD Ohio State University	Microglia are crucial mediators of stress-induced brain plasticity and behavioral vulnerability in mothers and offspring

2021

Date	Name	Description
January 12	J. Elliott Robinson, MD, PhD Cincinnati Children's Hospital Medical Center	Shining a (d)light on dopaminergic phenotypes in neurofibromatosis type 1
January 26	Natalie Norman Systems Biology and Physiology Alex Ruwe Systems Biology and Physiology	An exercise-driven, insulin-independent glucose uptake pathway in contracting skeletal muscle Mechanism of hepcidin inhibition of the iron exporter ferroportin
March 2	Yuhui Cao Systems Biology and Physiology Christopher Parker Systems Biology and Physiology	Roles of circadian rhythms in cell proliferation and tumor development Mathematical Modeling of the HPA Axis in PTSD
March 3	Christopher Rodgers, PhD Columbia University	Sensorimotor strategies and neuronal representations for shape recognition
March 9	Konstantinos Drosatos, PhD Temple University	Managing cardiac metabolism to treat cardiomyopathy
March 16	Susan George, MD, FRCP(C), FACP University of Toronto	Dopamine receptor complexes: novel signaling and functions in brain
April 13	Sevde Göker Systems Biology and Physiology Faiz Rizvi Systems Biology and Physiology	Circadian clock regulation of Notch-mediated differentiation in mouse intestinal epithelial cells maxATAC, a suite of user-friendly, deep neural network models for transcription factor binding prediction from ATAC-seq
April 14	Dongyin Guan, PhD University of Pennsylvania	Interconnections between circadian clocks and metabolism
April 20	Chen Gao, PhD University of California at Los Angeles School of Medicine	RNA metabolism in heart physiology - life beyond transcription
May 4	Nihal Ezgi Wood, PhD University of Texas Southwestern Medical Center	Uncovering noncanonical determinants that establish cell fate before commitment
May 25	Weirong Wang, PhD Johnson & Johnson	PK/PD considerations for CAR-T therapies
October 19	Yin Yeng Lee Systems Biology and Physiology Kit Qualls Molecular, Cellular, and Biochemical Pharmacology	Machine learning approaches to identify sleep regulators Corticosteroid receptor regulation of inflammatory low back pain in mice
October 26	Karthickeyan Chella Krishnan, PhD University of Cincinnati College of Medicine	Role of sex differences and mitochondrial dysfunction in non-alcoholic fatty liver disease
November 9	Anthony Glorius Systems Biology and Physiology Christina Thapa Systems Biology and Physiology	Examining grooming as a measure of stress-induced behaviors Single-nuclei sequencing to understand gene-expression changes in propriospinal neurons following spinal cord injury
November 30	Jeffrey Crocker Systems Biology and Physiology Latia Tucker Molecular, Cellular, and Biochemical Pharmacology	Autonomic remodeling and modulation as mechanism and therapy for spontaneous sudden cardiac death Cardiovascular mechanisms of endocrine disrupting chemicals
December 14	Sakhtivel Sadayappan, PhD, MBA University of Cincinnati College of Medicine	Skeletal paralogs of myosin binding protein-C in muscle physiology

2020

January 14	Ronald Vagnozzi, PhD Cincinnati Children's Hospital Medical Center	Rethinking regeneration: insights into cardiac wound healing from lineage tracing and cell-based therapies
February 18	A.P. Naren, PhD Cincinnati Children's Hospital Medical Center	Personalized medicine: pancreas-on-a-chip to study CFRD
February 25	Greg Harris, PhD University of Cincinnati College of Engineering and Applied Science	Investigating piezoelectric biomaterials to address traumatic nerve injuries
March 3	Robert McCullumsmith, MD, PhD University of Toledo College of Medicine and Life Sciences	Bioinformatics tools for the non-bioinformatically informed: pipette-free hypothesis testing, in silico drug discovery, and kinome array profiling
March 10	Seungwoo Kang, PhD Mayo Clinic	Role of astrocyte-neuron communication in reward seeking and alcohol addiction
September 1	Litsa Kranias, PhD University of Cincinnati College of Medicine	Calcium circuits in the heart: a matter of life and death
September 15	Yin-Yeng Lee Systems Biology and Physiology Samuel Slone Systems Biology and Physiology	Machine learning approaches to identify sleep regulators HuR-dependent regulation of inflammatory remodeling following myocardial ischemia/reperfusion injury
September 22	Jeffrey Crocker Systems Biology and Physiology Martha Dua-Awereh Systems Biology and Physiology	Autonomic remodeling and modulation as mechanism and therapy for spontaneous arrhythmogenic sudden cardiac death Metaplastic regeneration of the gastric epithelium and Helicobacter pylori-induced gastric disease in the elderly
October 13	Conor Liston, MD, PhD Weill Cornell Medicine Graduate School of Medical Sciences	Probing and rescuing dysfunctional brain circuits in depression
October 20	Shelly Flagel, PhD University of Michigan Medical School	Exploiting individual differences in reward learning to uncover the neural mechanisms underlying psychopathology
November 10	Satish Nair, PhD University of Missouri College of Engineering	Reverse engineering brain circuits
December 1	Catherine Makarewich, PhD Cincinnati Children's Hospital Medical Center	Dissecting the role of novel muscle-enriched microproteins

2019

January 8	Han Wang, PhD California Institute of Technology	Genetic and neural dissection of sleep in C. elegans
January 15	James Tidball, PhD University of California at Los Angeles	Regulatory interactions between muscle and the immune system in muscular dystrophy
January 22	Michael Sidorov, PhD University of North Carolina at Chapel Hill	Prefrontal circuits and behavior in mouse models of neurodevelopmental disorders
January 29	Surya Prasath, PhD Cincinnati Children's Hospital Medical Center	Computerized microvascular dura mater structure extraction and analysis from microscopy - image processing to deep learning
January 30	Adam Gracz, PhD University of North Carolina at Chapel Hill	Stem cell dynamics in intestinal and biliary epithelia
February 19	Kuei-Chun (Mark) Wang, PhD University of California at San Diego	Targeting atherosclerosis: from mechanobiology to nanomedicine
February 26	Amanda Zacharias, PhD Cincinnati Children's Hospital Medical Center	Context matters: a quantitative mechanism for the same signaling pathway to induce different cell fates
February 27	Isaac Cervantes-Sandoval, PhD The Scripps Research Institute - Scripps Florida	Cellular and molecular mechanisms of active forgetting
March 5	Philip Karpowicz, PhD University of Windsor	Circadian rhythms in intestinal health and disease?
March 12	Juan Sanchez Gurmaches, PhD Cincinnati Children's Hospital Medical Center	Tracing adipocyte origins and metabolism
March 26	Yuhui Cao Systems Biology and Physiology Drew Rosselot Systems Biology and Physiology	Circadian clock-dependent regulation of intestinal homeostasis and regeneration Intestinal circadian clock development and its role in the response to Clostridium difficile toxin B
April 2	Ted Hong Systems Biology and Physiology Sam Slone Systems Biology and Physiology	EBNA2 alters human gene regulatory network by extensively rewiring chromatin landscape The role of HuR in cardiac ischemia/reperfusion injury
April 23	Jeff Crocker Systems Biology and Physiology	Autonomic remodeling and modulation as mechanism and therapy for sudden cardiac death in heart failure
May 7	Rick Ballweg Systems Biology and Physiology Martha Dua-Awereh Systems Biology and Physiology	Integrating mechanistic modeling and machine learning to study intestinal stem cell proliferation Changes within the aged gastric epithelium after injury and regeneration may result in increased Helicobacter pylori-induced disease
May 14	Ertuğrul Özbudak Cincinnati Children's Hospital Medical Center	Cell signaling encodes temporal and positional information for pattern formation
May 21	Cynthia J. (C.J.) Musante, PhD Pfizer Inc.	The role of quantitative systems pharmacology in drug discovery and development
June 11	HaoDi Wu, PhD Stanford University	Dissecting the pathological mechanisms of cardiovascular disease with iPSCs
September 10	Diego Perez-Tilve, PhD University of Cincinnati College of Medicine	Control of fat stores by the brain
September 24	Xueguang Sun Cincinnati Children's Hospital Medical Center	The application of next generation sequencing in epigenome research
October 1	Katherine Vest, PhD University of Cincinnati	Post-transcriptional tuning of copper balance
October 8	John Harley, MD, PhD Cincinnati Children's Hospital Medical Center	Disease mechanisms from where transcription factors bind human DNA
October 15	Yuhui Cao Systems Biology and Physiology Ted Hong Systems Biology and Physiology	Circadian clock-dependent cell cycle and cell proliferation in intestinal epithelium EBNA2 alters human gene regulatory network by extensively rewiring chromatin landscape
October 22	Pablo Iglesias, PhD Johns Hopkins University	Excitable waves, set points, and cellular morphology
October 29	Alex Ruwe Systems Biology and Physiology Craig Thomson Systems Biology and Physiology	Transport mechanism of the mammalian iron exporter, ferroportin Non-canonical WNT5A regulates cytokine production in MPNST
November 5	Benjamin Prosser, PhD University of Pennsylvania	Cytoskeletal regulation of cardiac mechanobiology
November 12	Karthik Chella Krishnan, PhD University of California at Los Angeles	The power of natural variation: sex differences and mitochondrial function
November 19	Hee Woong Lim, PhD Cincinnati Children's Hospital Medical Center	Exploring enhancer landscape and regulation in high resolution
December 3	Yu-Chih Chen, PhD University of Michigan	Single-cell functional transcriptome and morphological analyses using machine learning for cancer discovery
December 10	Jianhua Xiong, PhD National Heart, Lung and Blood Institute, National Institutes of Health	Metabolic regulation of cell fate and function

2018

January 23	Julio Landero, PhD University of Cincinnati	New advances in elemental mass spectrometry and its impact on ion flux quantification in biological systems
January 30	Hong-Sheng Wang, PhD University of Cincinnati College of Medicine	Impact of environmental chemicals on cardiac arrhythmias
February 13	Kristen Engevik Systems Biology and Physiology Krithika Ramasamy-Subramanian Systems Biology and Physiology	Early responders to gastric epithelial damage Time-dependent alternative splicing in mammals
February 20	Richard Ballweg Systems Biology and Physiology	Understanding the proliferation dynamics of intestinal stem cells
February 27	Emma Teal Systems Biology and Physiology Craig Thomson Systems Biology and Physiology	CD44v9 and cystine-glutamate transporter (xCT) potentiate the defense against ROS to allow for effective healing in response to gastric injury Uncovering the role of WNT RTKs in MPNST tumorigenesis
March 6	Hamid Eghbalnia, PhD University of Wisconsin at Madison and University of Cincinnati College of Medicine	Estimating RNA-Seq differential expression: how complex is it?
March 20	Mark Frey, PhD University of Southern California	Neuregulin signaling in the intestine: controlling inflammation through contrasting effects on epithelial and immune cells
April 10	The John Maggio Memorial Lecture Dennis Selkoe, MD Brigham and Women's Hospital and Harvard Medical School	Deciphering the molecular bases of Alzheimer's and Parkinson's diseases yields novel therapies
April 17	Ted Hong Systems Biology and Physiology Andrew Rosselot Systems Biology and Physiology
May 8	Samantha Brugmann, PhD Cincinnati Children's Hospital Medical Center	Role of primary cilia in craniofacial development
May 15	Yaning Wang, PhD United States Food and Drug Administration	Balance between empiricism and mechanism
October 9	Timothy Pritts, MD, PhD University of Cincinnati College of Medicine	Resuscitation after trauma: understanding the effect of the red blood cell storage lesion
October 16	Lily Baek Systems Biology and Physiology	Circadian clock regulation of the glycogen metabolism in Neurospora crassa
October 23	Yvonne Ulrich-Lai, PhD University of Cincinnati College of Medicine	What puts the comfort in "comfort" foods?
October 30	Onur Kanisicak, PhD University of Cincinnati College of Medicine	In vivo characteristics of murine cardiac fibroblasts within normal and pathological heart
November 6	Kristen Engevik Systems Biology and Physiology Emma Teal Systems Biology and Physiology	Pathways in calcium-dependent gastric repair Metaplasia and tissue repair in gastric injury
November 13	Renu Sah, PhD University of Cincinnati College of Medicine	From acid-sensing to panic: contributions of a GPCR, TDAG8
November 20	Krithika Ramasamy-Subramanian Systems Biology and Physiology Craig Thomson Systems Biology and Physiology	A genome-wide analysis of circadian splicing in mammalian tissues Determining the role of Ror1 and Ror2 in a mouse model of progressive neurofibromas
November 27	Eric Wohleb, PhD University of Cincinnati College of Medicine	Integrating neuroimmune systems in the neurobiology of depression
December 4	Teresa Reyes, PhD University of Cincinnati College of Medicine	Development of a mouse model of leukemia survival to better inform treatment of long-term outcomes

2017

January 31	Jeffrey Osborn, PhD University of Kentucky	Mitochondrial DNA expression and hypertension: did mom really give you high blood pressure?
February 14	Gary Gudelsky, PhD University of Cincinnati James Winkle College of Pharmacy	The agony of 'ecstasy': neurotoxicity of MDMA
February 21	Chia-Ying James Lin, PhD University of Cincinnati College of Medicine	Bioinspired scaffold design with hierarchical tissue properties to facilitate skeletal tissue
February 28	Andrew Paek, PhD University of Arizona	Measuring protein dynamics in single cells reveals mechanisms of chemotherapy resistance
March 7	Edward Kasarskis, MD, PhD University of Kentucky	Nutrition, appetite, and ALS
March 21	Michael Jankowski, PhD Cincinnati Children's Hospital Medical Center	The many marvels of muscle afferents
April 11	Hesam Hakimjavadi Systems Biology and Physiology Krithika Ramasamy-Subramanian Systems Biology and Physiology	Fight or flight (but do not fatigue!): sodium pump regulation of skeletal muscle stress response Role of alternative splicing in circadian rhythm regulation
May 9	Eitaro Aihara, PhD University of Cincinnati College of Medicine	Impact of Helicobacter pylori on peptic ulcers: induction, healing, and recurrence
May 23	Lily Baek Systems Biology and Physiology Drew Rosselot Systems Biology and Physiology	Interconnected network between circadian rhythms and glycogen metabolism The effect of age and Clostridium difficile toxins on the circadian clock of organoids
September 12	Andrew Norman, PhD University of Cincinnati College of Medicine	A Physiological Pharmacology approach to understanding cocaine self-administration behavior
September 26	Chang-Guo Zhan, PhD University of Kentucky	Drug discovery and development via rational design
October 3	Georg Weber, MD, PhD University of Cincinnati James Winkle College of Pharmacy	Molecular mechanisms of metastasis
October 24	Elizabeta Nemeth, PhD University of California at Los Angeles School of Medicine	From anemia to iron overload and infection: pathobiology of iron
October 31	Li Wang, PhD University of Connecticut	LncRNA and nuclear receptor in liver function and disease
November 7	Reto Asmis, PhD University of Texas at San Antonio	Macrophages and the redox regulation of the immunometabolic interface
November 14	Qiong Yang, PhD University of Michigan	From molecules to development: understanding design principles of biological oscillators
November 21	Hamid Said, PhD University of California School of Medicine	Physiology/pathophysiology of water-soluble vitamin transport in organs of the digestive system
November 28	Daria Narmoneva, PhD University of Cincinnati College of Engineering	Using biophysics to direct wound healing and vascular tissue regeneration
December 5	Jeffrey Osborn, PhD University of Kentucky	Translating basic science to clinical medicine: identifying the animal model for renal and cardiovascular disease
December 12	David Hui, PhD University of Cincinnati College of Medicine	Apolipoprotein E receptor-2 (LRP8): much more than a lipoprotein raceptor in cardiovascular disease modulation

2016

February 16	Computational Systems Biology Seminar Guang Yao, PhD University of Arizona	Controlling the heterogeneous growth response of quiescent cells by a gene network switch
February 23	Joseph Broderick, MD University of Cincinnati College of Medicine	Sea change in acute stroke therapy
March 1	Mitsi Blount, PhD Emory University	The importance of urea transport for medullary sodium reabsorption
March 8	Robert Hester, PhD University of Mississippi Medical Center	Mathematical simulation of integrative physiology: history and the future
March 29	Kim Seroogy, PhD University of Cincinnati College of Medicine	Neurotoxin and genetic rat models of Parkinson's disease: impact of chronic stress
April 19	Karl Obrietan, PhD The Ohio State University	ERK/MAPK kinase signaling and circadian clock timing circuits of the CNS
April 26	Hesamedin Hakimjavadi Systems Biology and Physiology	Mathematical modelling of sodium pump dynamics and its role in skeletal muscle excitability
May 10	Vakul Mohanty Systems Biology and Physiology Christina Wei Systems Biology and Physiology	Selective DNA methylation compensates coupled with gross structural genomic changes shapes optimal tumor transcriptome Gsk3-Beta-CUGBP1 signaling as a therapeutic target for myotonic dystrophy type 1
May 17	Mary Beth Yacyshyn, PhD University of Cincinnati College of Medicine	C. difficile infection: what the human model can tell us
June 8	Computational Systems Biology Seminar Andrew Oates, PhD The Francis Crick Institute	Period and pattern in the embryo
September 13	Xiaonan Han, PhD Cincinnati Children's Hospital Medical Center	Activation of stem cell regeneration to repair impaired intestinal barriers
September 20	Computational Systems Biology Seminar Tongli Zhang, PhD University of Cincinnati College of Medicine	A modular modeling approach for understanding cellular fate decision making
October 4	Teresa Reyes, PhD University of Cincinnati College of Medicine	Perinatal diet affects brain development: a role for DNA methylation and inflammation
October 11	Computational Systems Biology Seminar Jiajie Diao, PhD University of Cincinnati College of Medicine	Ultra-sensitive single-molecule quantification of DNA epigenetic modifications
October 18	Vakul Mohanty Systems Biology and Physiology Jeremy Riddell Systems Biology and Physiology	Selective DNA methylation in cancers controls collateral damage induced by large structural variations Computational prediction of transcription factor composite motifs
October 25	Christina Wei Systems Biology and Physiology	The role of GSK3β-CUGBP1 pathway in the correction of DM1 muscle pathology
November 1	Yana Zavros, PhD University of Cincinnati College of Medicine	Development of patient-derived in vivo and in vitro models of gastric cancer
November 8	Computational Systems Biology Seminar Nathan Salomonis, PhD Cincinnati Children's Hospital Medical Center	Understanding disease at the level of single cells and alternative splicing
November 15	Computational Systems Biology Seminar Harinder Singh, PhD Cincinnati Children's Hospital Medical Center	Systems analysis of bifurcating cellular trajectories and developmental fate specification
November 22	Bryan Mackenzie, PhD University of Cincinnati College of Medicine	Iron imports 2016
November 29	Nina Bertaux-Skeirik Systems Biology and Physiology Kristen Engevik Systems Biology and Physiology	CD44v emerges in response to injury and contributes to the regeneration of the gastric epithelium Use of gastric organoids in elucidating the role of TFF and EGF in restitution

2015

January 13	Lubov Timchenko, PhD Cincinnati Children's Hospital Medical Center	Myotonic dystrophy: pathogenic mechanisms and new therapies
January 20	Steven Crone, PhD Cincinnati Children's Hospital Medical Center	A circuit mechanism of degeneration in ALS
February 3	Holly Algood, PhD Vanderbilt University School of Medicine	Gastric inflammation in response to Helicobacter pylori: a dichotomy of help and harm
March 10	Surya Nauli, PhD Chapman University School of Pharmacy	Roles of sensory primary cilia in disease and therapy
March 24	Computational Systems Biology Seminar Christian Hong, PhD University of Cincinnati School of Medicine	Functional roles of circadian rhythms in cell cycle and DNA damage response
April 14	Rulang Jiang, PhD Cincinnati Children's Hospital Medical Center	Integration of signaling pathways in patterning the mammalian face
April 21	Steven Kleene, PhD University of Cincinnati College of Medicine	Calcium signaling in the renal primary cilium
April 22	Computational Systems Biology Seminar James E. Ferrell, Jr., MD, PhD Stanford University School of Medicine	Trigger waves in mitosis and apoptosis
April 28	James Wells, PhD Cincinnati Children's Hospital Medical Center
May 12	Steven Potter, PhD Cincinnati Children's Hospital Medical Center	Single cell dissection of organogenesis
May 18	Peter Lauf, MD Wright State University School of Medicine	Na⁺/K⁺ pump ATPase and Bcl-2 proteins: an oligomeric bio-sensor controlling cellular life and death?
May 26	Computational Systems Biology Seminar Jianhua Xing, PhD University of Pittsburgh School of Medicine	Cooperative molecular interactions lead to monoallelic expression of olfactory receptors
September 8	Judith Heiny, PhD University of Cincinnati College of Medicine	Regulation of the Na,K-ATPase α2 isoform in skeletal muscle: the turbocharger isoform
September 22	Theresa Alenghat, VMD, PhD Cincinnati Children's Hospital Medical Center	The host-microbiota relationship and intestinal homeostasis
September 29	Mark Baccei, PhD University of Cincinnati College of Medicine	Aberrant synaptic signaling in spinal pain circuits after neonatal tissue damage
October 6	Yutaka Yoshida, PhD Cincinnati Children's Hospital Medical Center	Neural circuits in motor systems
October 13	Takahisa Nakamura, PhD Cincinnati Children's Hospital Medical Center	Inflammatory RISK and RISC in type 2 diabetes
November 3	Computational Systems Biology Seminar Timothy Elston, PhD University of North Carolina School of Medicine	Polarity establishment and gradient sensing in yeast
November 10	James Herman, PhD University of Cincinnati College of Medicine	The systems biology of stress
November 17	Robert Koncar Systems Biology and Physiology Jeremy Riddell Systems Biology and Physiology	Inhibition of Polo-like kinase 1 enhances temozolomide efficacy in a model of isocitrate dehydrogenase 1 mutant gliomas Computational prediction of transcription factor composite elements
November 24	Lily Baek Systems Biology and Physiology Nina Bertaux-Skeirik Systems Biology and Physiology	Interdisciplinary approaches for identification of interaction between circadian rhythms and glycogen metabolism Studies of gastric disease using mouse- and human-derived organoids
December 1	Bruce Yacyshyn, MD University of Cincinnati College of Medicine	Translational research in the inflammatory bowel diseases

2014

February 11	Katherine Yutzey, PhD Cincinnati Children's Hospital Medical Center	Heart valve disease, lessons from development
February 18	AP Naren, PhD Cincinnati Children's Hospital Medical Center	The CFTR interactome in health and disease
March 25	Maria Czyzyk-Krzeska, MD, PhD University of Cincinnati College of Medicine	MicroRNA networks in regulation of oncogenic autophagy in renal cancer
April 1	Marino DiFranco, PhD UCLA	Optogenic control of skeletal muscle
April 8	George Deepe, MD University of Cincinnati College of Medicine	Granulocyte-macrophage colony stimulating factor regulates zinc availability to fungal pathogens
April 15	Laurie Nommsen-Rivers, PhD, RD, IBCLC Cincinnati Children's Hospital Medical Center	The impact of maternal obesity and insulin resistance on lactation sufficiency
May 13	Max Reif, MD University of Cincinnati College of Medicine	Essential hypertension
May 20	David Richards, PhD Cincinnati Children's Hospital Medical Center	Vesicle highways and byways: how secretory vesicles find their way to release sites
August 28	Computational Systems Biology Seminar John Hogenesch, PhD University of Pennsylvania School of Medicine	The landscape of circadian gene expression – implications for biology and medicine
October 3	Computational Systems Biology Seminar John Tyson, PhD Virginia Polytechnic Institute and State University	What can mathematical modeling teach us about cell cycle regulation?
October 7	Sarah Pixley, PhD University of Cincinnati College of Medicine	Magnesium metal as a bioresorbable medical implant material
October 14	Begoña Campos, PhD University of Cincinnati College of Medicine	Biodegradable maturation enhancing stent for arteriovenous fistula
October 21	Ronald Waclaw, MS, PhD Cincinnati Children's Hospital Medical Center	Signaling pathways controlling oligodendrocyte development
October 28	Brian Siroky, PhD Cincinnati Children's Hospital Medical Center	Primary cilia and the hyperosmolal renal microenvironment
November 4	Aaron Zorn, PhD Cincinnati Children's Hospital Medical Center	Regulatory networks in embryonic lung development
November 18	Karyn Esser, PhD University of Kentucky College of Medicine	Circadian rhythms, molecular clock, and skeletal muscle. Why muscles need to keep time.
November 25	Richard Lang, PhD Cincinnati Children's Hospital Medical Center	Vascular development of the eye is regulated by myeloid Wnt ligands and a fetal light response pathway
December 2	Raphael Kopan, PhD Cincinnati Children's Hospital Medical Center	Defying time: from progenitors to nephrons
December 11	Computational Systems Biology Seminar Tongli Zhang, PhD University of Oxford	How experimentalists and modelers can collaborate to gain a deeper understanding of cellular decision making

2013

January 8	Joseph Clark, PhD University of Cincinnati College of Medicine	Creatine transporter-deficient mice: a model for human disease
January 22	Yana Zavros, PhD University of Cincinnati College of Medicine	Indian Hedgehog mediates gastrin-induced proliferation in the adult stomach
February 5	Rhett Kovall, PhD University of Cincinnati College of Medicine	Structure and function of Notch transcription complexes
February 12	Ron Millard, PhD University of Cincinnati College of Medicine	Stem cells: biological therapeutic delivery devices for tissue reconstruction
February 19	Joo-Seop Park, PhD Cincinnati Children's Hospital Medical Center	Cell-fate regulation of nephron progenitors
March 5	Zubair Ahmed, PhD Cincinnati Children's Hospital Medical Center	Role of usher proteins in the inner ear and retina structure and function
March 12	David Wieczorek, PhD University of Cincinnati College of Medicine
April 2	Kakajan Komurov, PhD Cincinnati Children's Hospital Medical Center	Integrative modeling of the EGFR family-driven tumorigenic platform
April 9	Marshall Montrose, PhD University of Cincinnati College of Medicine	Sequential mobilization of intracellular and extracellular calcium during repair of microscopic gastric lesions
April 16	David Plas, PhD University of Cincinnati College of Medicine	Targeting metabolic-signaling networks in cancer therapy
July 19	Metiner Tosun, PhD Ege University, Izmir, Turkey	Functional consequences of TRPC1-silencing in Huh-7 hepatocellular carcinoma cell line
August 27	Brian Gebelein, PhD Cincinnati Children's Hospital Medical Center	Enhanceosomes, billboards or collectives: how HOX factors regulate cell-specific gene expression
September 10	Susan Wells, PhD Cincinnati Children's Hospital Medical Center	Fanconi anemia pathway: repairing the gap between DNA damage and squamous cell carcinoma
September 17	Shekhar Gandhi, PhD Cincinnati Children's Hospital Medical Center	Stellate cells in hepatic inflammation and immune regulation
September 24	Sang-Wook Cha, PhD Cincinnati Children's Hospital Medical Center	Insights into adhesion and polarity from Xenopus and gut organoids
October 1	Ana Luisa Kadekaro, PhD University of Cincinnati College of Medicine	Role of epidermal melanocytes in attenuating UVR-induced skin carcinogenesis
October 8	Per Hellstrand, PhD Lund University	Stretch-mediated effects on growth and differentiation of vascular smooth muscle
October 15	Josh Benoit, PhD University of Cincinnati	Lactating flies: mechanisms underlying mammalian-like milk production in Glossina morsitans
October 22	David Haslam, MD Cincinnati Children's Hospital Medical Center	Intestinal immunity and on the role of normal bacteria in preventing Clostridium difficile infection
October 31	Zheng (Jake) Chen, PhD University of Texas at Houston	Clock-modulating small molecules improve circadian rhythms and protect against metabolic syndrome
November 5	KyoungHyun Kim, PhD University of Cincinnati College of Medicine	ZBTB4, a novel target of oncogenic microRNAs in breast cancer
November 12	Joshua Gross, PhD University of Cincinnati	A genetic basis for activity differences in response to light in the blind Mexican cavefish, Astyanax mexicanus
November 19	Tiffany Cook, PhD University of Cincinnati College of Medicine	Coordinating the development of a sensory organ: insights from the Drosophila eye
December 3	Matthew Weirauch, PhD Cincinnati Children's Hospital Medical Center	Global determination and inference of eukaryotic transcription factor binding specificities

2012

January 3	Daniel Hassett, PhD University of Cincinnati College of Medicine	Mechanisms of killing mucoid MucA mutant Pseudomonas aeruginosa in cystic fibrosis airway disease: Just say NO!
January 10	Silvana Obici, MD University of Cincinnati College of Medicine	Exercising the brain: role of physical exercise in the CNS control of energy homeostasis
January 17	Andrew Norman, PhD University of Cincinnati College of Medicine	Of mice and men: translational research on a human, monoclonal antibody to treat cocaine addiction
January 24	Laura Conforti, PhD University of Cincinnati College of Medicine	The ion channel network in human T lymphocytes
January 31	Charles Vorhees, PhD Cincinnati Children's Hospital Medical Center	Methamphetamine: effects on brain development and function
February 7	Timothy Pritts, MD, PhD University of Cincinnati College of Medicine	Hemorrage and resuscitation
February 14	Fumika Hamada, PhD Cincinnati Children's Hospital Medical Center	Thermoregulation in Drosophila
February 28	Saulius Sumanas, PhD Cincinnati Children's Hospital Medical Center	How to make a blood vessel: insight from the zebrafish
March 6	Maria Czyzyk-Krzeska, MD, PhD University of Cincinnati College of Medicine	VHL-dependent networks regulate autophagy in renal cancer
March 13	Alex Lentsch, PhD University of Cincinnati College of Medicine	Diverse roles of chemokines in liver injury, repair, and regeneration
March 27	Noah Shroyer, PhD Cincinnati Children's Hospital Medical Center	Differentiation factors as tumor suppressors: Notch/Atoh1 in colon cancer
April 3	James Eliassen, PhD University of Cincinnati College of Medicine	Learning, brain activity, and the effects of recreational drug use
April 10	Steven Boyce, PhD University of Cincinnati College of Medicine, Shriner's Burns Institute	Translational research with engineered human skin
April 17	Dr. Kirk Hamilton University of Otago	Molecular trafficking of KCa3.1- a new game?
April 24	Timothy Pritts, MD, PhD University of Cincinnati College of Medicine	Impact of resuscitation strategy on response to hemorrhagic shock
May 1	Peter Stambrook PhD University of Cincinnati College of Medicine	Complexities of cell cycle regulation and preservation of genomic integrity
May 8	Susan Waltz, PhD University of Cincinnati College of Medicine	Multiple roles for the Ron receptor in promoting tumor growth
May 15	Simon Hogan, PhD Cincinnati Children's Hospital Medical Center	Intestinal epithelial secretion modulates severity of food-triggered anaphylaxis
May 22	Sheila Fleming, PhD University of Cincinnati	Behavioral phenotypes in genetic mouse models of Parkinson's disease
May 29	Stephen Benoit, PhD University of Cincinnati College of Medicine	Endocrine, behavioral and brain effects of bariatric surgery: from memory to addiction
June 5	Sean Moore, MD Cincinnati Children's Hospital Medical Center	Glutamine as gut repair nutrient: mechanisms in malnourished mice
June 12	Satoshi Namekawa, PhD Cincinnati Children's Hospital Medical Center	Journey of the sex chromosomes through reproduction and evolution
September 4	Nelson Horseman, PhD University of Cincinnati College of Medicine	Mammary epithelial homeostasis and breast cancer
September 11	Jeffrey Johnson, PhD University of Cincinnati College of Engineering	A computational model of the role of dopamine in signaling of the medium spiny neuron in the dorsal lateral striatum
September 25	Simon Hogan, PhD Cincinnati Children's Hospital Medical Center	Intestinal epithelial secretion modulates severity of food-triggered anaphylaxis
October 2	Keith Jones, PhD University of Cincinnati College of Medicine	MicroRNAs and gene expression networks in the heart
October 9	Paul Andreassen, PhD Cincinnati Children's Hospital Medical Center	Breast cancer (BRCA) susceptibility genes: Insights into DNA damage responses from human disease
October 16	Malak Kotb, PhD University of Cincinnati College of Medicine	Translational approaches for discovering underlying mechanisms of human diseases & developing personalized targeted prevention and intervention strategies
October 23	John MacLennan, PhD University of Cincinnati College of Medicine	A chronicle of H218/S1P2 sphingosine 1-phosphate 2 receptor adventures
October 30	Prof. Heini Murer University of Zürich	An update on cellular mechanisms in renal and intestinal phosphate handling
November 20	Keith Jones, PhD University of Cincinnati College of Medicine	MicroRNAs and gene expression networks in the heart
November 27	Judy Heiny, PhD University of Cincinnati College of Medicine	The Na,K-ATPase a2 isoform keeps us moving.
December 4	Carolyn Price, PhD University of Cincinnati College of Medicine	Rescuing replication: role of mammalian CST at telomeres and replication forks
December 11	Dr. Bruno Stieger University Hospital Zürich	From molecular mechanisms of bile salt transport to liver function tests

2011

January 4	Mario Medvedovic, PhD Cincinnati Children's Hospital Medical Center and University of Cincinnati	Using public-domain genomics data to interpret results of new genomics experiments
January 18	Evangelia (Litsa) Kranias, PhD University of Cincinnati College of Medicine	Calcium circuits in the heart: a matter of life and death
February 8	David Abbott, PhD University of Wisconsin–Madison	Metabolomic and epigenetic contributions to developmental programming of female reproductive and metabolic dysfunction
February 22	Christian Hong, PhD University of Cincinnati College of Medicine	Molecular mechanism of circadian rhythms in Neurospora crassa
March 1	Khawaja Haider, MPharm, PhD University of Cincinnati College of Medicine	Stem cells for myocardial regeneration
April 12	David Plas, PhD Unviersity of Cincinnati College of Medicine	Controlling the switches that regulate oncogenic metabolism
April 26	Steven Potter, PhD Cincinnati Children's Hospital Medical Center	Microdissection of the genetic program of neurogenesis
May 10	John Cuppoletti, PhD University of Cincinnati College of Medicine	Prostones as ion-channel activators and treatments for disease
May 24	Thomas Beck, PhD University of Cincinnati	Computational studies of ion transport through H⁺/Cl^– transporters
May 31	Peter Stambrook, PhD University of Cincinnati College of Medicine	Maintaining genomic integrity in somatic and embryonic stem cells
June 17	Markus Paulmichl, MD Paracelsus Medical University	Structure-function relation of human pendrin: the role of pendrin in asthma bronchiale

2010

January 12	Kris Steinbrecher, PhD Cincinnati Children's Hospital Medical Center	Epithelial GSK-3β and NF-κB in intestinal inflammation
January 26	Laura Conforti, PhD University of Cincinnati Medical Center	Ion channel mobility and function in autoimmunity
February 2	Kim Seroogy, PhD University of Cincinnati Medical Center	Chronic variable stress exacerbates experimental Parkinsonism
February 23	Daria Narmoneva, PhD University of Cincinnati Medical Center	Regulation of angiogenesis by endothelial cell microenvironment
March 9	Anil Menon, PhD University of Cincinnati Medical Center	Fetal programming of adult physiology
April 6	Jorge Bezerra, MD Cincinnati Children's Hospital Medical Center
May 21	The Daniel L. Kline Lecturer in Systems Biology and Physiology James Bassingthwaighte, MD, PhD University of Washington	Integrative multilevel analysis: the physiome approach Problem solving in physiological data interpretation
August 31	David Wieczorek, PhD University of Cincinnati College of Medicine	Molecular and functional characterization of a novel cardiac-specific human tropomyosin isoform
September 14	Randy Seeley, PhD University of Cincinnati College of Medicine	How obesity went to our heads: CNS regulation of energy balance
October 19	Hassane Amlal, PhD University of Cincinnati of Medicine	Role of renal glutamine transport and ammoniagenesis in the regulation acid-base balance
October 26	Keith Jones, PhD University of Cincinnati	Protecting the heart from ischemic injury using the skin
October 28	East Coast Iron Club Plenary Lecture Tomas Ganz, PhD, MD David Geffen University of California at Los Angeles School of Medicine	Iron homeostasis and its disorders: from molecules to treatments
November 16	Jarek Meller, PhD Cincinnati Children's Hospital	Prediction of classical human leukocyte-antigen (HLA) alleles from SNP data

2009

January 13	Jeffrey Robbins, PhD Cincinnati Children's Hospital Medical Center	Commonalities between the heart and mind: an unfolding story
February 3	Christopher M Gillen, PhD Kenyon College	Size matters: exploring the role of body size on gut nutrient transport in an insect model system
February 10	The Darwin Bicentennial Celebration Lecture Kenneth Petren, PhD University of Cincinnati	A beagle's eye view of bio-diversity in Darwin's finches
February 24	Deborah Kurrasch, PhD University of California at San Francisco	Uncovering developmental programs that define neuroendocrine centers
March 3	Diego Restrepo, PhD University of Colorado at Denver	Profound context-dependent plasticity of mitral cell responses in olfactory bulb
March 10	Jeffrey Kordower, PhD Rush University	A tale of two stories: why nigral neurons die in Parkinson's disease and how to save them
April 7	George Thomas, PhD University of Cincinnati College of Medicine	Of ribosome biogenesis, cell-cycle checkpoints and cancer progression
April 28	State-of-the-Art Clinical Physiology Series Robert Luke, MB ChB, FRCP University of Cincinnati College of Medicine	The salt-hypertension link
May 8	The Daniel L Kline Lecturer in Systems Biology and Physiology Dennis Brown, PhD Harvard Medical School and Massachusetts General Hospital	Systems biology: a rose by any other name Systems physiology: practical examples from the MGH Program in Membrane Biology
May 12	Alessio Accardi, PhD University of Iowa Carver College of Medicine	Mechanisms of ion binding and selectivity in the CLC transporters and channels Co-sponsored by the Department of Chemistry
September 8	Nira Ben-Jonathan, PhD University of Cincinnati College of Medicine	Prolactin as a growth and survival factor in breast cancer
September 30	Gary Sieck, PhD Mayo Clinic, Rochester	Role of neurotrophins in recovery of respiratory motor function after spinal-cord injury
October 6	State-of-the-Art Clinical Physiology Series David Weiner, MD University of Florida at Gainesville	Molecular mechanisms of ammonia transport: Pitts might have been wrong
October 27	Kenneth Greis, PhD University of Cincinnati College of Medicine	Mass spectrometry in biomedical research: practical applications and unexpected challenges
November 24	S K Dey, PhD Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine	Molecular roadmap to embryo implantation

2008

January 8	Jeffrey Whitsett, MD Cincinnati Children's Hospital Medical Center	Transcriptional networks regulating lung formation and function
January 22	Alex Lentsch, PhD University of Cincinnati College of Medicine	Regulation of post-ischemic liver injury by CXC chemokines
January 29	James Herman, PhD University of Cincinnati College of Medicine	Neurocircuits controlling stress physiology
February 5	Thomas Beck, PhD University of Cincinnati	Ion-transit pathways and gating in bacterial H⁺/Cl⁻ transporters
February 26	John Layne, PhD University of Cincinnati	Paradoxical relationship between spatial orientation and stabilizing reflexes
March 4	Marc Rothenberg, MD, PhD Cincinnati Children's Hospital Medical Center	Molecular control of eosinophilia
March 11	David Askew, PhD University of Cincinnati College of Medicine	Unexpected functions for the programmed cell death machinery in the human fungal pathogen Aspergillus fumigatus
April 1	Sean Stocker, PhD University of Kentucky	Modulation of sympathetic-cardiovascular circuits by dietary salt: new mechanisms for salt-sensitive hypertension
April 22	Bruce Schultz, PhD Kansas State University College of Veterinary Medicine	GRIP1 is required for ENaC expression in mammary epithelial cells
April 29	Jorge Moscat, PhD University of Cincinnati College of Medicine	Atypical PKC signaling in inflammation and cancer
May 6	Xiaojuan Chen, MD, PhD Northwestern University Feinberg School of Medicine	Islet transplantation: From imaging to β-cell regeneration
May 8	The Dean's Distinguished Lecturer in Physiology Tomas Ganz, PhD, MD David Geffen University of California at Los Angeles School of Medicine	Regulation of plasma iron by hepcidin and ferroportin
May 23	The Daniel L Kline Lecturer in Systems Biology and Physiology Roger Brent, PhD Molecular Sciences Institute	Systems biology of cell-signaling systems: It's all about the information
May 27	Takafumi Hamaoka, MD, PhD National Institute of Fitness and Sports, Kagoshima, and Tokyo Medical University	Near-infrared spectroscopy for monitoring muscle oxygenation and oxidative metabolism in healthy and diseased humans Sponsored by the Department of Neurology
June 3	David Robbins, PhD Dartmouth Medical School	Exploring the role of Hedgehog signaling in human disease
September 9	Richard Paul, PhD University of Cincinnati College of Medicine	Plasma-membrane calcium ATPase (PMCA) isoforms: compartmentation in smooth muscle?
September 30	Muhammad Ashraf, PhD University of Cincinnati College of Medicine	Smart stem cells to enhance repair following myocardial infarction
October 7	John Williams, MD, PhD University of Michigan	Pancreatic plasticity: nutrients as well as GI hormones regulate the size of the pancreas
October 14	Bruce Aronow, PhD Cincinnati Children's Hospital Medical Center	Using integrative systems biology for physiology and disease research
October 28	Lewis Adams, PhD Griffith University	Neural correlates for the perception of dyspnea in humans
November 4	David Hui, PhD University of Cincinnati College of Medicine	Intestinal lipid transport and metabolism: targets for treatment of atherosclerosis, obesity, and diabetes
December 2	Brian Gebelein, PhD Cincinnati Children's Hospital Medical Center	Integrating genetic pathways that pattern the nervous system

2007

January 9	James Lessard, PhD Cincinnati Children's Hospital Medical Center	Using the muscle actin genes to study function and disease and development
January 23	Brad Warner, MD Cincinnati Children's Hospital Medical Center	Studies of resection-induced intestinal adaptation
January 30	Keith Jones, PhD University of Cincinnati	NF-κB in cardiovascular pathophysiology: the good, the bad, and the ugly
February 27	David Wieczorek, PhD University of Cincinnati	Understanding tropomyosin function in the heart
March 6	Ernest Wright, DSc David Geffen University of California at Los Angeles School of Medicine	Imaging functional activity of sugar transporters in mice and men
March 13	Joseph Broderick, MD University of Cincinnati College of Medicine	Course and treatment of intracerebral hemorrhage
March 20	Yan Xu, PhD Cincinnati Children's Hospital Medical Center	Gene expression profiling: from numeric-based approaches to knowledge-based approaches
March 27	Neal Weintraub, MD University of Cincinnati College of Medicine	Perivascular adipocytes: a new player in atherosclerosis
April 3	Jo El Schultz, PhD University of Cincinnati College of Medicine	Opioidergic system in the pathology of heart failure
April 10	Hannah Carey, PhD University of Wisconsin School of Veterinary Medicine	Mammalian hibernation: a model for natural resistance to stress and trauma
April 24	Steven Boyce, PhD University of Cincinnati College of Medicine and Shriners Burns Institute	Tissue engineering for closure of skin wounds: principles and practices
May 8	James Goldenring, MD, PhD Vanderbilt University School of Medicine	Origin of gastric pre-neoplasia: a role for transdifferentiation
May 16	The Dean's Distinguished Lecturer in Physiology Allen W Cowley, PhD Medical College of Wisconsin	Genetic and physiological architecture of cardiovascular function and hypertension Genetic determinants and mechanisms of renal oxidative stress
May 22	The Daniel L Kline Lecturer in Systems Biology and Physiology Lewis A Chodosh, MD, PhD University of Pennsylvania School of Medicine	Understanding mammary development and tumorigenesis: Computational biology meets the mouse
May 29	Simon Hogan, PhD Cincinnati Children's Hospital Medical Center	Pathophysiological mechanisms of intestinal anaphylaxis
September 4	Jay Hove, PhD University of Cincinnati College of Medicine	Small fish, big pond: the emerging role of the zebrafish in biomedical research
September 11	Leslie Myatt, PhD University of Cincinnati College of Medicine	Oxidative and nitrative stress in the placenta: functional effects
September 24	Hamid Eghbalnia, PhD University of Wisconsin	The buzz about systems modeling: from the structure of a sweet protein to septic shock
September 25	Zachary Spicer, PhD University of Cincinnati College of Medicine Sunil G Nair, MBBS University of Cincinnati College of Medicine	Synthesis and evaluation of a novel probe for isolating and identifying serotonin-modified proteins Bilirubin oxidation products (BOXes) in delayed cerebral vasospasm after subarachnoid hemorrhage
October 2	Randy Seeley, PhD University of Cincinnati College of Medicine	How obesity went to our heads: the CNS and the regulation of body weight
October 8	Curtis Jamison, PhD Northern Kentucky University College of Informatics	Variation, complexity, and robustness
October 9	Evangelia Kranias, PhD University of Cincinnati College of Medicine	Targeting calcium cycling as a therapeutic modality in heart failure
October 23	Michael Behbehani, PhD University of Cincinnati College of Medicine	Sensitization of glutamate receptors in hormone-related migraine
October 24	Yong Kong, PhD Keck Foundation Biotechnology and Resource Laboratory at Yale University	How to blast biological databases faster and better than BLAST
October 30	Marshall Montrose, PhD University of Cincinnati College of Medicine	Epithelial repair in the GI tract: scary events
November 6	Gary Shull, PhD University of Cincinnati College of Medicine	Mutations in the SERCA2 and SPCA1 calcium pumps cause squamous-cell tumors in mice
November 13	Teresa Wood, PhD New Jersey Medical School	Insulin, IGF, and hybrid receptors in mammary epithelial cells: the plot thickens for IGF signaling
November 27	Silvana Obici, MD University of Cincinnati College of Medicine	Nutrient sensing in the CNS: malonyl CoA as a biochemical sensor of nutrient availability

2006

January 11	Carol Lange, PhD University of Minnesota Cancer Center	Integration of progesterone receptor (PR) and MAP kinase actions in breast cancer models
January 18	John Lorenz, PhD University of Cincinnati College of Medicine	Na,K-ATPase and the regulation of glomerular hemodynamics
January 25	Bradley Britigan, MD University of Cincinnati College of Medicine	Pseudomonas secretory products, oxygen radicals, and lung injury
February 1	Basil Hanss, PhD Mt. Sinai Medical Center	Substrate specificity of the nucleic acid channel
February 8	Patrick Tso, PhD University of Cincinnati College of Medicine	Why is it important for the gut to make apolipoprotein A-IV?
February 9	James Stockand, PhD University of Texas at San Antonio	Regulation of the epithelial Na channel (ENaC) by small G proteins and phosphatidylinositides
February 15	Malinda Stull, PhD University of Cincinnati College of Medicine	Serotonergic regulation of transepithelial resistance in breast epithelial cells
February 22	Jacob Friedman, PhD University of Colorado	Maternal obesity and cellular mechanisms of insulin resistance: setting the stage for fetal obesity
March 1	Phyllis Callahan, PhD Miami University	Orphanin FQ/nociceptin regulation of prolactin secretion
March 15	Elke Buschbeck, PhD University of Cincinnati	Fourteen retinas but only six eyes: the larval visual system of the diving beetle Thermonectus marmoratus (Dytiscidae)
March 22	Jarek Meller, PhD Cincinnati Children's Hospital Medical Center	Computational studies of proteins and their interactions: computational biology and bioinformatics online tools
March 29	Zalfa Abdel-Malek, PhD University of Cincinnati College of Medicine	Regulation of human pigmentation by paracrine factors: implications on the response of melanocytes to ultraviolet radiation and melanoma susceptibility
April 12	John MacLennan, PhD University of Cincinnati College of Medicine	In vivo studies of CNTF receptors: motorneurons, muscle and neural stem cells
April 13	Yana Zavros, PhD University of Michigan	Pepsinogen and its role in Sonic Hedgehog processing in normal and cancer tissue
April 19	George Thomas, PhD University of Cincinnati College of Medicine	The role of the nutrient input in TSC1/2-Rheb-mediated mTOR signaling
April 26	Christy Holland, PhD University of Cincinnati Colleges of Medicine and Engineering	The evolution of ultrasound contrast agents: from diagnostics to therapeutics
May 3	Alicia McDonough, PhD University of Southern California Keck School of Medicine	Renal sodium transport regulation by blood pressure, ACE inhibitors, and salt
May 8	Shougang Zhuang, MD Medical University of South Carolina	Epidermal growth factor receptor: a critical regulator of renal epithelial cell regeneration
May 16	Pamela Knapp, PhD University of Kentucky	Glial cells: perpetrators and targets of inflammation and injury in the CNS
May 17	William Chilian, PhD Louisiana State University School of Medicine	Reactive oxygen species: are they all bad?
May 24	Michael O'Leary, PhD Jefferson Medical College	Molecular mechanisms of local anesthetic binding to voltage-gated sodium channels
September 5	Yanfang Guan, PhD University of Cincinnati College of Medicine Amy Dugan, PhD University of Cincinnati College of Medicine	Two-photon imaging in vivo study of intestinal ischemic preconditioning Impact of psychological stress on the immune response: a mouse model
September 12	Erik Knudsen, PhD University of Cincinnati College of Medicine	A tumor suppressor learns new tricks: lessons from retinoblastoma
September 26	Jay Hove, PhD University of Cincinnati College of Medicine	A small fish in a big pond: the emerging role of zebrafish in biomedical research
October 3	Manoocher Soleimani, MD University of Cincinnati College of Medicine	How important are SLC26 bicarbonate transporters in kidney, pancreas, and gastrointestinal tract?
October 10	Begoña Campos, PhD University of Cincinnati College of Medicine	Role of annexins in pregnancy
October 31	Caroline Enns, PhD Oregon Health and Science University	Hereditary hemochromatosis: a family of dysfunctional proteins
November 7	Matthias Tschöp, MD University of Cincinnati College of Medicine	Neuroendocrine regulation of body weight
November 28	Theresa Powell, PhD University of Cincinnati College of Medicine	Nutrient transport in human placenta and its role in fetal growth
December 5	Ursula Seidler, MD Hannover Medical School	New aspects of intestinal ion transport regulation by PDZ-adapter proteins of the NHERF family
December 12	Susan Waltz, PhD University of Cincinnati College of Medicine	The Ron-receptor tyrosine kinase in mammary biology

2005

January 19	Roger Worrell, PhD University of Cincinnati	Ammonium not just for cleaning: role in the colon
January 26	Tong Jemay Wang, PhD Yale University	Regulation of sodium and bicarbonate transport in kidney proximal tubule
February 2	Michael Romero, PhD Case Western Reserve University	Electrogenic Na⁺/HCO₃⁻ co-transport: clues from disease, structure, and model organisms
February 9	Tracy Pritchard University of Cincinnati College of Medicine Min Gu University of Cincinnati College of Medicine	Role of the Na⁺/K⁺-ATPase alpha isoforms in vascular smooth muscle and hypertension Calcium-independent hypoxic vaso-relaxation: role of the rho pathway
February 16	Masato Nakafuku, MD, PhD Cincinnati Children's Hospital Medical Center	Neural stem cells and brain self-repair: an old theme and new task
February 23	Jeffrey Matthews, MD University of Cincinnati College of Medicine	Regulation of epithelial transport and barrier function by PKC
March 2	John Maggio, PhD University of Cincinnati College of Medicine	Protein misfolding and misassembly in disease: AB, amyloid, and Alzheimer disease
March 23	Todd Penberthy, PhD University of Cincinnati College of Medicine	Zebrafish functional genomics and niacin status in vertebrate survival response to stress
April 13	Jonna Fraser, PhD University of Illinois	Estrogen and SERMs: selective regulation of gene expression in breast-cancer cells
April 19	Pamela Lloyd Indiana University
April 21	Lydia Arbogast, PhD Southern Illinois University
April 26	Weibin Shi, MD, PhD University of Virginia
April 28	Carolyn Ecelbarger, PhD Georgetown University
October 19	Joseph Clark, PhD University of Cincinnati College of Medicine	Pathophysiology of bleeding in the brain
October 26	Laura Conforti, PhD University of Cincinnati College of Medicine	Hypoxia and T-cell activation: the plasma-membrane viewpoint
November 2	Snezana Petrovic, PhD, FASN University of Cincinnati College of Medicine	Acid-base regulation and the kidney collecting duct
November 9	Elwood Jensen, PhD University of Cincinnati College of Medicine	Curious pharmacology of the antiestrogens
November 16	Maria Czyzyk-Krzeska, MD, PhD University of Cincinnati College of Medicine
November 30	Mitchell Cohen, PhD Cincinnati Children's Hospital Medical Center
December 7	Jerry Lingrel, PhD University of Cincinnati College of Medicine	Structure-function of the Na⁺/K⁺-ATPase α isoforms
December 14	Anil Menon, PhD University of Cincinnati College of Medicine	Metabolic syndrome

2004

January 14	Alier Franco University of Cincinnati College of Medicine	The role of corticotropin-releasing factor in stress-induced analgesia
January 21	Winston Kao, PhD University of Cincinnati College of Medicine	Molecular and cellular mechanism of ocular surface tissues morphogenesis
January 28	Lique Coolen, PhD University of Cincinnati College of Medicine	Sex and the single rat: a nerobiological perspective
February 4	Timothy Weaver, MS, PhD Cincinnati Children's Hospital Medical Center	Protein misfolding and disease: identification of molecular pathways linking SP-C mutations to interstitial lung disease
February 11	Randall Sakai, PhD University of Cincinnati College of Medicine	Mice cloned from somatic cells have an obese phenotype
February 18	David Pollock, PhD Medical College of Georgia	Renal mechanisms in hyperstension: understanding the physiology of endothelin
February 25	Jeffrey Robbins, PhD Cincinnati Children's Hospital Research Foundation	Cardiomyopathy and the neurodegenerative diseases: a shared pathology?
March 3	Harold Gould, PhD	Alterations in sodium channels in inflammatory pain
March 17	Carlos Subauste, MD University of Cincinnati College of Medicine
March 24	Thomas Kleyman, MD University of Pittsburgh
April 28	John Dedman, PhD University of Cincinnati College of Medicine
September 22	Adi Haramati, PhD Georgetown University School of Medicine	Regulation of phosphate homeostasis during growth: evidence for a brain-kidney link
October 13	Manoocher Soleimani, MD University of Cincinnati College of Medicine
October 20	Jeff Elmendorf, PhD Indiana University - Purdue University Indianapolis
October 27	Lara Gawenis, PhD University of Cincinnati College of Medicine
November 3	Marc Wathelet, PhD University of Cincinnati College of Medicine
November 10	Robert Isofort
November 17	Fred Finkelman, MD University of Cincinnati College of Medicine
December 1	James Pauly, PhD University of Kentucky College of Pharmacy
December 8	Kenneth Campbell, PhD Cincinnati Children's Hospital Medical Center
December 15	Richard Day, PhD University of Virginia Health Sciences Center

2003

February 5	Marshall Montrose, PhD Indiana University School of Medicine
February 12	Jeffrey Whitsett, MD Cincinnati Children's Hospital Medical Center
February 19	Martha Cruz-Soto University of Cincinnati College of Medicine
February 26	John Cuppoletti, PhD University of Cincinnati College of Medicine
March 5	Robert Sorenson, PhD University of Minnesota
March 12	Karl Matlin, PhD University of Cincinnati College of Medicine
March 19	Fahmeed Hyder, PhD Yale University
March 26	Richard Paul, PhD University of Cincinnati College of Medicine
April 2	Patrick Tso, PhD University of Cincinnati College of Medicine
April 9	Joseph Kao, PhD University of Maryland
April 23	Christopher Wylie, PhD Cincinnati Children's Hospital Medical Center
April 30	Kim Barrett, PhD University of California at San Diego
May 7	William Welch, PhD Georgetown University
May 14	Thomas Clemens, PhD University of Cincinnati College of Medicine
May 21	Frank Sharp, MD University of Cincinnati College of Medicine
May 28	Rodney Dekoter, PhD University of Cincinnati College of Medicine
September 24	Mitchell Lazar, MD, PhD University of Pennsylvania	Transcriptional repression by nuclear receptors
October 1	Raymund Pun, PhD University of Cincinnati College of Medicine	Can worms smell? Preliminary recordings from sensory neurons of Caenorhabditis elegans
October 8	Balint Kacsoh, MD, PhD Mercer University School of Medicine	Regulation of growth hormone in dw/dw dwarf rats
October 15	Nicholas Sperelakis, PhD University of Cincinnati College of Medicine	The heart is a giant syncytium - true or false?
October 22	Thomas DeCoursey, PhD Rush Presbyterian St. Luke's Medical Center	Interactions between the phagocyte NADPH oxidase and voltage-gated proton channels
October 29	Pamela Davis, MD, PhD Case Western Reserve University	Inflammatory responses in the CF lung
November 5	Nelson Horseman, PhD University of Cincinnati College of Medicine	Mammary gland physiology: systemic and local homeostasis
November 19	David Cook, PhD University of Sydney
December 3	James Stockard, PhD
December 10	Scott Belcher, PhD University of Cincinnati College of Medicine
December 17	Keith Crutcher, PhD University of Cincinnati College of Medicine

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Pharmacology, Physiology, & Neurobiology
College of Medicine
231 Albert Sabin Way
Cincinnati, OH 45267-0575