Education/CredentialsFellowship: The University of Texas MD Anderson Cancer Center Doctoral Degree: Peking Union Medical College (Immunology)Master's Degree: Peking Union Medical College (Immunology)Medical Degree: Anhui Medical University Contact Information Vontz Center 1308 Office 513-558-2176 Email dongzu@ucmail.uc.edu Research InterestsProstate Cancer, IFN-b Gene Therapy, Angiogenesis, PCNA inhibitor, Androgen receptor inhibitor, Androgen receptor Peer Reviewed Publications Dong, Zhongyun; Meller, Jaroslaw; Succop, Paul; Wang, Jiang; Wikenheiser-Brokamp, Kathryn; Starnes, Sandra; Lu, Shan 2014. Secretory phospholipase A2-IIa upregulates HER/HER2-elicited signaling in lung cancer cells. International journal of oncology, 45 3, 978-84Chou, Da-Tren; Hong, Daeho; Saha, Partha; Ferrero, Jordan; Lee, Boeun; Tan, Zongqing; Dong, Zhongyun; Kumta, Prashant N 2013. In vitro and in vivo corrosion, cytocompatibility and mechanical properties of biodegradable Mg-Y-Ca-Zr alloys as implant materials. Acta biomaterialia, 9 10, 8518-33Hong, Daeho; Saha, Partha; Chou, Da-Tren; Lee, Boeun; Collins, Boyce E; Tan, Zongqing; Dong, Zhongyun; Kumta, Prashant N 2013. In vitro degradation and cytotoxicity response of Mg-4% Zn-0.5% Zr (ZK40) alloy as a potential biodegradable material. Acta biomaterialia, 9 10, 8534-47Cui, L., Chen, P., Tan, Z., and Dong, Z. 2012. Hemostatic gelatin sponge is a superior matrix to Matrigel for estabishment of LNCaP human prostate cancer in nude mice Prostate, DOI:10 1002/, pros. 22520Cui, L., Dillehay, K. L., Chen, W., Shen, D., Dong, Z., W. Li 2012. Association of the CYP1B1 Leu432Val polymorphism with the risk of prostate cancer: a meta-analysis Mol Biol Reports, 39 , 7465-71Cui, Lingling; Chen, Pingping; Tan, Zongqing; Li, Wenjie; Dong, Zhongyun 2012. Hemostatic gelatin sponge is a superior matrix to matrigel for establishment of LNCaP human prostate cancer in nude mice. The Prostate, 72 15, 1669-77Oleksowicz, L., Jiu, Y., Bracken, R.B, Gaitonde, K., Burke, B., Succop, P., Levin, L., Dong, Z., and Lu,S. 2012. Secretory Phospholipase A2-lla is a Target Gene of the HER/HER2-Elicited Pathway and Potential Plasma Biomarket for Poor Prognosis of Prostate Cancer Prostate, 72 , 1140-49Oleksowicz, Leslie; Liu, Yin; Bracken, R Bruce; Gaitonde, Krishnanath; Burke, Barbara; Succop, Paul; Levin, Linda; Dong, Zhongyun; Lu, Shan 2012. Secretory phospholipase A2-IIa is a target gene of the HER/HER2-elicited pathway and a potential plasma biomarker for poor prognosis of prostate cancer. The Prostate, 72 10, 1140-9Tan, Z., Chen, P., Schneider, N., Glover, S., Cui, L., Torgue, J., Rixe, O., Spitz, H. B., an Dong, Z. 2012. Significant systemic therapeutic effects of high-LET immunoradiation by Pb-trastuzumab against prostatic tumors of androgen-independent human prostate cancer in mice Int J. Oncol, 40 , 1881-1888Tan, Z., Wortman, M., Dillehay, K.L., Seibel, W., Evelyn, C. R., Smith, S. J., Malkas, L., Zheng, Y., Lu, S., and Dong, Z. 2012. Small molecule targeting of PCNA chromatin association inhibits tumor cell growth Mol Pharmacol, 81 , 811-9Tan, Zongqing; Chen, Pingping; Schneider, Nathan; Glover, Samuel; Cui, Lingling; Torgue, Julien; Rixe, Olivier; Spitz, Henry B; Dong, Zhongyun 2012. Significant systemic therapeutic effects of high-LET immunoradiation by 212Pb-trastuzumab against prostatic tumors of androgen-independent human prostate cancer in mice. International journal of oncology, 40 6, 1881-8Tan, Zongqing; Wortman, Matthew; Dillehay, Kelsey L; Seibel, William L; Evelyn, Chris R; Smith, Shanna J; Malkas, Linda H; Zheng, Yi; Lu, Shan; Dong, Zhongyun 2012. Small-molecule targeting of proliferating cell nuclear antigen chromatin association inhibits tumor cell growth. Molecular pharmacology, 81 6, 811-9Xue, D., Yun Y., Tan Z., Dong Z., and M. J. Schultz 2012. In Vivo and In Vitro degradation behavior of magnesium alloys as biomaterials J. Mat. Sci. Tech., , Yun, Y., Pixley, S., X. Cui, T., Dong, Z., Collins, B., Shanov, V., Ko, S., Pai1, D., Yarmolenko, S., Schulz, M. J., and J. Sankar 2012. Carbon Nanomaterials: From Therapeutics to Regenerative Medicine Nanomedicine and Biotherapeutic Discovery, 2 , 1000104Dong, Zhongyun; Liu, Yin; Levin, Linda; Oleksowicz, Leslie; Wang, Jiang; Lu, Shan 2011. Vav3 oncogene is involved in regulation of secretory phospholipase A2-IIa expression in prostate cancer. Oncology reports, 25 6, 1511-6Kupert, E., Anderson, M. Liu, Y., Succop, P., Levin, L., Wang, J., Wikenheisser-Brokamp, K., Chen, P., Ponney, S., Macdonald, T., Dong, Z., Starnes, S. and Lu, S. 2011. Plasma secretory phospholipase A2-lla as a potential biomarker for lung cancer in patients with solitary pulmonary nodules BMC Cancer, 11 , 513Kupert, Elena; Anderson, Marshall; Liu, Yin; Succop, Paul; Levin, Linda; Wang, Jiang; Wikenheiser-brokamp, Kathryn; Chen, Pingping; Pinney, Susan M; Macdonald, Trudy; Dong, Zhongyun; Starnes, Sandra; Lu, Shan 2011. Plasma secretory phospholipase A2-IIa as a potential biomarker for lung cancer in patients with solitary pulmonary nodules. BMC cancer, 11 , 513Cho, Hoon-Sung; Dong, Zhongyun; Pauletti, Giovanni M; Zhang, Jiaming; Xu, Hong; Gu, Hongchen; Wang, Lumin; Ewing, Rodney C; Huth, Christopher; Wang, Feng; Shi, Donglu 2010. Fluorescent, superparamagnetic nanospheres for drug storage, targeting, and imaging: a multifunctional nanocarrier system for cancer diagnosis and treatment. ACS nano, 4 9, 5398-404Dong, Zhongyun; Liu, Yin; Scott, Kieran F; Levin, Linda; Gaitonde, Krishnanath; Bracken, R Bruce; Burke, Barbara; Zhai, Qihui Jim; Wang, Jiang; Oleksowicz, Leslie; Lu, Shan 2010. Secretory phospholipase A2-IIa is involved in prostate cancer progression and may potentially serve as a biomarker for prostate cancer. Carcinogenesis, 31 11, 1948-55Liu, Yin; Wu, Xiaoyang; Dong, Zhongyun; Lu, Shan 2010. The molecular mechanism of Vav3 oncogene on upregulation of androgen receptor activity in prostate cancer cells. International journal of oncology, 36 3, 623-33Lu, Shan; Tan, Zongqin; Wortman, Matt; Lu, Shan; Dong, Zhongyun 2010. Regulation of heat shock protein 70-1 expression by androgen receptor and its signaling in human prostate cancer cells. International journal of oncology, 36 2, 459-67Lu, Shan; Tan, Zongqin; Wortman, Matthew; Lu, Shan; Dong, Zhongyun 2010. Preferential induction of G1 arrest in androgen-responsive human prostate cancer cells by androgen receptor signaling antagonists DL3 and antiandrogen bicalutamide. Cancer letters, 298 2, 250-7Meng, Qinghang; Peng, Zhimin; Chen, Liang; Si, Jutong; Dong, Zhongyun; Xia, Ying 2010. Nuclear Factor-?B modulates cellular glutathione and prevents oxidative stress in cancer cells. Cancer letters, 299 1, 45-53Yun, YeoHeung; Dong, Zhongyun; Tan, Zongqing; Schulz, Mark J 2010. Development of an electrode cell impedance method to measure osteoblast cell activity in magnesium-conditioned media. Analytical and bioanalytical chemistry, 396 8, 3009-15Yun, Yeo-Heung; Eteshola, Edward; Bhattacharya, Amit; Dong, Zhongyun; Shim, Joon-Sub; Conforti, Laura; Kim, Dogyoon; Schulz, Mark J; Ahn, Chong H; Watts, Nelson 2009. Tiny medicine: nanomaterial-based biosensors. Sensors (Basel, Switzerland), 9 11, 9275-99Guo, Yan; Shi, Donglu; Lian, Jie; Dong, Zhongyun; Wang, Wei; Cho, Hoonsung; Liu, Guokui; Wang, Lumin; Ewing, Rodney C 2008. Quantum dot conjugated hydroxylapatite nanoparticles for in vivo imaging. Nanotechnology, 19 17, 175102Lee, Kiwon; Liu, Yin; Mo, Jun Qin; Zhang, Jinsong; Dong, Zhongyun; Lu, Shan 2008. Vav3 oncogene activates estrogen receptor and its overexpression may be involved in human breast cancer. BMC cancer, 8 , 158Liu, Yin; Mo, Jun Qin; Hu, Qiande; Boivin, Gregory; Levin, Linda; Lu, Shan; Yang, Dianer; Dong, Zhongyun; Lu, Shan 2008. Targeted overexpression of vav3 oncogene in prostatic epithelium induces nonbacterial prostatitis and prostate cancer. Cancer research, 68 15, 6396-406Lu, Shan; Lee, Juwon; Revelo, Monica; Wang, Xiaohong; Lu, Shan; Dong, Zhongyun 2007. Smad3 is overexpressed in advanced human prostate cancer and necessary for progressive growth of prostate cancer cells in nude mice. Clinical cancer research : an official journal of the American Association for Cancer Research, 13 19, 5692-702Lu, Shan; Wang, Amy; Lu, Shan; Dong, Zhongyun 2007. A novel synthetic compound that interrupts androgen receptor signaling in human prostate cancer cells. Molecular cancer therapeutics, 6 7, 2057-64Wang, Daren; Lu, Shan; Dong, Zhongyun 2007. Regulation of TGF-beta1 gene transcription in human prostate cancer cells by nitric oxide. The Prostate, 67 16, 1825-33Yun, YeoHeung; Bange, Adam; Shanov, Vesselin N; Heineman, William R; Halsall, H Brian; Dong, Zhongyun; Jazieh, Abdul; Tu, Yi; Wong, Danny; Pixley, Sarah; Behbehani, Michael; Schulz, Mark J 2007. A carbon nanotube needle biosensor. Journal of nanoscience and nanotechnology, 7 7, 2293-300Yun, Yeoheung; Dong, Zhongyun; Shanov, Vesselin N; Schulz, Mark J 2007. Electrochemical impedance measurement of prostate cancer cells using carbon nanotube array electrodes in a microfluidic channel. Nanotechnology, 18 46, 465505Yun, Yeoheung; Gollapudi, Ram; Shanov, Vesselin; Schulz, Mark J; Dong, Zhongyun; Jazieh, Abdul; Heineman, William R; Halsall, H Brian; Wong, Danny K Y; Bange, Adam; Tu, Yi; Subramaniam, Srinivas 2007. Carbon nanotubes grown on stainless steel to form plate and probe electrodes for chemical/biological sensing. Journal of nanoscience and nanotechnology, 7 3, 891-7Dong, Zhongyun; Liu, Yin; Lu, Shan; Wang, Amy; Lee, Kiwon; Wang, Lu-Hai; Revelo, Monica; Lu, Shan 2006. Vav3 oncogene is overexpressed and regulates cell growth and androgen receptor activity in human prostate cancer. Molecular endocrinology (Baltimore, Md.), 20 10, 2315-25Lee, Juwon; Wang, Amy; Hu, Qiande; Lu, Shan; Dong, Zhongyun 2006. Adenovirus-mediated interferon-beta gene transfer inhibits angiogenesis in and progression of orthotopic tumors of human prostate cancer cells in nude mice. International journal of oncology, 29 6, 1405-12Lu, Shan; Dong, Zhongyun 2006. Characterization of TGF-beta-regulated interleukin-8 expression in human prostate cancer cells. The Prostate, 66 9, 996-1004Zhang, Fahao; Lee, Juwon; Wang, Daren; Dong, Zhongyun 2006. Differential growth of IFN-beta-engineered tumor cells in nude and IFN receptor-null mice. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 26 2, 108-18Liu, Guozhen; Zhang, Fahao; Lee, Juwon; Dong, Zhongyun 2005. Selective induction of interleukin-8 expression in metastatic melanoma cells by transforming growth factor-beta 1. Cytokine, 31 3, 241-9Uehara, Hisanori; Troncoso, Patricia; Johnston, Dennis; Bucana, Corazon D; Dinney, Colin; Dong, Zhongyun; Fidler, Isaiah J; Pettaway, Curtis A 2005. Expression of interleukin-8 gene in radical prostatectomy specimens is associated with advanced pathologic stage. The Prostate, 64 1, 40-9Zhang, Fahao; Lee, Juwon; Lu, Shan; Pettaway, Curtis A; Dong, Zhongyun 2005. Blockade of transforming growth factor-beta signaling suppresses progression of androgen-independent human prostate cancer in nude mice. Clinical cancer research : an official journal of the American Association for Cancer Research, 11 12, 4512-20Lu, Weixin; Su, Jindong; Kim, Lee Su; Bucana, Corazon D; Donawho, Cherrie; He, Junqing; Fidler, Isaiah J; Dong, Zhongyun 2003. Active specific immunotherapy against occult brain metastasis. Cancer research, 63 6, 1345-50Ozawa, Shutaro; Lu, Weixin; Bucana, Corazon D; Kanayama, Hiro-Omi; Shinohara, Hisashi; Fidler, Isaiah J; Dong, Zhongyun 2003. Regression of primary murine colon cancer and occult liver metastasis by intralesional injection of lyophilized preparation of insect cells producing murine interferon-beta. International journal of oncology, 22 5, 977-84Davies, Michael A; Kim, Sun J; Parikh, Nila U; Dong, Zhongyun; Bucana, Corazon D; Gallick, Gary E 2002. Adenoviral-mediated expression of MMAC/PTEN inhibits proliferation and metastasis of human prostate cancer cells. Clinical cancer research : an official journal of the American Association for Cancer Research, 8 6, 1904-14Harmey, Judith H; Bucana, Corazon D; Lu, Weixin; Byrne, Anne Marie; McDonnell, Susan; Lynch, Conor; Bouchier-Hayes, David; Dong, Zhongyun 2002. Lipopolysaccharide-induced metastatic growth is associated with increased angiogenesis, vascular permeability and tumor cell invasion. International journal of cancer. Journal international du cancer, 101 5, 415-22Izawa, Jonathan I; Sweeney, Paul; Perrotte, Paul; Kedar, Daniel; Dong, Zhongyun; Slaton, Joel W; Karashima, Takashi; Inoue, Keji; Benedict, William F; Dinney, Colin P N 2002. Inhibition of tumorigenicity and metastasis of human bladder cancer growing in athymic mice by interferon-beta gene therapy results partially from various antiangiogenic effects including endothelial cell apoptosis. Clinical cancer research : an official journal of the American Association for Cancer Research, 8 4, 1258-70Lu, Weixin; Dong, Zhongyun; Donawho, Cherrie; Fidler, Isaiah J 2002. Specific immunotherapy against occult cancer metastases. International journal of cancer. Journal international du cancer, 100 4, 480-5Makar, Tapas Kumar; Wilt, Susan; Dong, Zhongyun; Fishman, Paul; Mouradian, M Maral; Dhib-Jalbut, Suhayl 2002. IFN-beta gene transfer into the central nervous system using bone marrow cells as a delivery system. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 22 7, 783-91Takeuchi, Osamu; Sato, Shintaro; Horiuchi, Takao; Hoshino, Katsuaki; Takeda, Kiyoshi; Dong, Zhongyun; Modlin, Robert L; Akira, Shizuo 2002. Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins. 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Research InterestsProstate Cancer, IFN-b Gene Therapy, Angiogenesis, PCNA inhibitor, Androgen receptor inhibitor, Androgen receptor
Peer Reviewed Publications Dong, Zhongyun; Meller, Jaroslaw; Succop, Paul; Wang, Jiang; Wikenheiser-Brokamp, Kathryn; Starnes, Sandra; Lu, Shan 2014. Secretory phospholipase A2-IIa upregulates HER/HER2-elicited signaling in lung cancer cells. International journal of oncology, 45 3, 978-84Chou, Da-Tren; Hong, Daeho; Saha, Partha; Ferrero, Jordan; Lee, Boeun; Tan, Zongqing; Dong, Zhongyun; Kumta, Prashant N 2013. In vitro and in vivo corrosion, cytocompatibility and mechanical properties of biodegradable Mg-Y-Ca-Zr alloys as implant materials. Acta biomaterialia, 9 10, 8518-33Hong, Daeho; Saha, Partha; Chou, Da-Tren; Lee, Boeun; Collins, Boyce E; Tan, Zongqing; Dong, Zhongyun; Kumta, Prashant N 2013. In vitro degradation and cytotoxicity response of Mg-4% Zn-0.5% Zr (ZK40) alloy as a potential biodegradable material. Acta biomaterialia, 9 10, 8534-47Cui, L., Chen, P., Tan, Z., and Dong, Z. 2012. Hemostatic gelatin sponge is a superior matrix to Matrigel for estabishment of LNCaP human prostate cancer in nude mice Prostate, DOI:10 1002/, pros. 22520Cui, L., Dillehay, K. L., Chen, W., Shen, D., Dong, Z., W. Li 2012. Association of the CYP1B1 Leu432Val polymorphism with the risk of prostate cancer: a meta-analysis Mol Biol Reports, 39 , 7465-71Cui, Lingling; Chen, Pingping; Tan, Zongqing; Li, Wenjie; Dong, Zhongyun 2012. Hemostatic gelatin sponge is a superior matrix to matrigel for establishment of LNCaP human prostate cancer in nude mice. The Prostate, 72 15, 1669-77Oleksowicz, L., Jiu, Y., Bracken, R.B, Gaitonde, K., Burke, B., Succop, P., Levin, L., Dong, Z., and Lu,S. 2012. Secretory Phospholipase A2-lla is a Target Gene of the HER/HER2-Elicited Pathway and Potential Plasma Biomarket for Poor Prognosis of Prostate Cancer Prostate, 72 , 1140-49Oleksowicz, Leslie; Liu, Yin; Bracken, R Bruce; Gaitonde, Krishnanath; Burke, Barbara; Succop, Paul; Levin, Linda; Dong, Zhongyun; Lu, Shan 2012. Secretory phospholipase A2-IIa is a target gene of the HER/HER2-elicited pathway and a potential plasma biomarker for poor prognosis of prostate cancer. The Prostate, 72 10, 1140-9Tan, Z., Chen, P., Schneider, N., Glover, S., Cui, L., Torgue, J., Rixe, O., Spitz, H. B., an Dong, Z. 2012. Significant systemic therapeutic effects of high-LET immunoradiation by Pb-trastuzumab against prostatic tumors of androgen-independent human prostate cancer in mice Int J. Oncol, 40 , 1881-1888Tan, Z., Wortman, M., Dillehay, K.L., Seibel, W., Evelyn, C. R., Smith, S. J., Malkas, L., Zheng, Y., Lu, S., and Dong, Z. 2012. Small molecule targeting of PCNA chromatin association inhibits tumor cell growth Mol Pharmacol, 81 , 811-9Tan, Zongqing; Chen, Pingping; Schneider, Nathan; Glover, Samuel; Cui, Lingling; Torgue, Julien; Rixe, Olivier; Spitz, Henry B; Dong, Zhongyun 2012. Significant systemic therapeutic effects of high-LET immunoradiation by 212Pb-trastuzumab against prostatic tumors of androgen-independent human prostate cancer in mice. International journal of oncology, 40 6, 1881-8Tan, Zongqing; Wortman, Matthew; Dillehay, Kelsey L; Seibel, William L; Evelyn, Chris R; Smith, Shanna J; Malkas, Linda H; Zheng, Yi; Lu, Shan; Dong, Zhongyun 2012. Small-molecule targeting of proliferating cell nuclear antigen chromatin association inhibits tumor cell growth. Molecular pharmacology, 81 6, 811-9Xue, D., Yun Y., Tan Z., Dong Z., and M. J. Schultz 2012. In Vivo and In Vitro degradation behavior of magnesium alloys as biomaterials J. Mat. Sci. Tech., , Yun, Y., Pixley, S., X. Cui, T., Dong, Z., Collins, B., Shanov, V., Ko, S., Pai1, D., Yarmolenko, S., Schulz, M. J., and J. Sankar 2012. Carbon Nanomaterials: From Therapeutics to Regenerative Medicine Nanomedicine and Biotherapeutic Discovery, 2 , 1000104Dong, Zhongyun; Liu, Yin; Levin, Linda; Oleksowicz, Leslie; Wang, Jiang; Lu, Shan 2011. Vav3 oncogene is involved in regulation of secretory phospholipase A2-IIa expression in prostate cancer. Oncology reports, 25 6, 1511-6Kupert, E., Anderson, M. Liu, Y., Succop, P., Levin, L., Wang, J., Wikenheisser-Brokamp, K., Chen, P., Ponney, S., Macdonald, T., Dong, Z., Starnes, S. and Lu, S. 2011. Plasma secretory phospholipase A2-lla as a potential biomarker for lung cancer in patients with solitary pulmonary nodules BMC Cancer, 11 , 513Kupert, Elena; Anderson, Marshall; Liu, Yin; Succop, Paul; Levin, Linda; Wang, Jiang; Wikenheiser-brokamp, Kathryn; Chen, Pingping; Pinney, Susan M; Macdonald, Trudy; Dong, Zhongyun; Starnes, Sandra; Lu, Shan 2011. Plasma secretory phospholipase A2-IIa as a potential biomarker for lung cancer in patients with solitary pulmonary nodules. BMC cancer, 11 , 513Cho, Hoon-Sung; Dong, Zhongyun; Pauletti, Giovanni M; Zhang, Jiaming; Xu, Hong; Gu, Hongchen; Wang, Lumin; Ewing, Rodney C; Huth, Christopher; Wang, Feng; Shi, Donglu 2010. Fluorescent, superparamagnetic nanospheres for drug storage, targeting, and imaging: a multifunctional nanocarrier system for cancer diagnosis and treatment. ACS nano, 4 9, 5398-404Dong, Zhongyun; Liu, Yin; Scott, Kieran F; Levin, Linda; Gaitonde, Krishnanath; Bracken, R Bruce; Burke, Barbara; Zhai, Qihui Jim; Wang, Jiang; Oleksowicz, Leslie; Lu, Shan 2010. Secretory phospholipase A2-IIa is involved in prostate cancer progression and may potentially serve as a biomarker for prostate cancer. Carcinogenesis, 31 11, 1948-55Liu, Yin; Wu, Xiaoyang; Dong, Zhongyun; Lu, Shan 2010. The molecular mechanism of Vav3 oncogene on upregulation of androgen receptor activity in prostate cancer cells. International journal of oncology, 36 3, 623-33Lu, Shan; Tan, Zongqin; Wortman, Matt; Lu, Shan; Dong, Zhongyun 2010. Regulation of heat shock protein 70-1 expression by androgen receptor and its signaling in human prostate cancer cells. International journal of oncology, 36 2, 459-67Lu, Shan; Tan, Zongqin; Wortman, Matthew; Lu, Shan; Dong, Zhongyun 2010. Preferential induction of G1 arrest in androgen-responsive human prostate cancer cells by androgen receptor signaling antagonists DL3 and antiandrogen bicalutamide. Cancer letters, 298 2, 250-7Meng, Qinghang; Peng, Zhimin; Chen, Liang; Si, Jutong; Dong, Zhongyun; Xia, Ying 2010. Nuclear Factor-?B modulates cellular glutathione and prevents oxidative stress in cancer cells. Cancer letters, 299 1, 45-53Yun, YeoHeung; Dong, Zhongyun; Tan, Zongqing; Schulz, Mark J 2010. Development of an electrode cell impedance method to measure osteoblast cell activity in magnesium-conditioned media. Analytical and bioanalytical chemistry, 396 8, 3009-15Yun, Yeo-Heung; Eteshola, Edward; Bhattacharya, Amit; Dong, Zhongyun; Shim, Joon-Sub; Conforti, Laura; Kim, Dogyoon; Schulz, Mark J; Ahn, Chong H; Watts, Nelson 2009. Tiny medicine: nanomaterial-based biosensors. Sensors (Basel, Switzerland), 9 11, 9275-99Guo, Yan; Shi, Donglu; Lian, Jie; Dong, Zhongyun; Wang, Wei; Cho, Hoonsung; Liu, Guokui; Wang, Lumin; Ewing, Rodney C 2008. Quantum dot conjugated hydroxylapatite nanoparticles for in vivo imaging. Nanotechnology, 19 17, 175102Lee, Kiwon; Liu, Yin; Mo, Jun Qin; Zhang, Jinsong; Dong, Zhongyun; Lu, Shan 2008. Vav3 oncogene activates estrogen receptor and its overexpression may be involved in human breast cancer. BMC cancer, 8 , 158Liu, Yin; Mo, Jun Qin; Hu, Qiande; Boivin, Gregory; Levin, Linda; Lu, Shan; Yang, Dianer; Dong, Zhongyun; Lu, Shan 2008. Targeted overexpression of vav3 oncogene in prostatic epithelium induces nonbacterial prostatitis and prostate cancer. Cancer research, 68 15, 6396-406Lu, Shan; Lee, Juwon; Revelo, Monica; Wang, Xiaohong; Lu, Shan; Dong, Zhongyun 2007. Smad3 is overexpressed in advanced human prostate cancer and necessary for progressive growth of prostate cancer cells in nude mice. Clinical cancer research : an official journal of the American Association for Cancer Research, 13 19, 5692-702Lu, Shan; Wang, Amy; Lu, Shan; Dong, Zhongyun 2007. A novel synthetic compound that interrupts androgen receptor signaling in human prostate cancer cells. Molecular cancer therapeutics, 6 7, 2057-64Wang, Daren; Lu, Shan; Dong, Zhongyun 2007. Regulation of TGF-beta1 gene transcription in human prostate cancer cells by nitric oxide. The Prostate, 67 16, 1825-33Yun, YeoHeung; Bange, Adam; Shanov, Vesselin N; Heineman, William R; Halsall, H Brian; Dong, Zhongyun; Jazieh, Abdul; Tu, Yi; Wong, Danny; Pixley, Sarah; Behbehani, Michael; Schulz, Mark J 2007. A carbon nanotube needle biosensor. Journal of nanoscience and nanotechnology, 7 7, 2293-300Yun, Yeoheung; Dong, Zhongyun; Shanov, Vesselin N; Schulz, Mark J 2007. Electrochemical impedance measurement of prostate cancer cells using carbon nanotube array electrodes in a microfluidic channel. Nanotechnology, 18 46, 465505Yun, Yeoheung; Gollapudi, Ram; Shanov, Vesselin; Schulz, Mark J; Dong, Zhongyun; Jazieh, Abdul; Heineman, William R; Halsall, H Brian; Wong, Danny K Y; Bange, Adam; Tu, Yi; Subramaniam, Srinivas 2007. Carbon nanotubes grown on stainless steel to form plate and probe electrodes for chemical/biological sensing. Journal of nanoscience and nanotechnology, 7 3, 891-7Dong, Zhongyun; Liu, Yin; Lu, Shan; Wang, Amy; Lee, Kiwon; Wang, Lu-Hai; Revelo, Monica; Lu, Shan 2006. Vav3 oncogene is overexpressed and regulates cell growth and androgen receptor activity in human prostate cancer. Molecular endocrinology (Baltimore, Md.), 20 10, 2315-25Lee, Juwon; Wang, Amy; Hu, Qiande; Lu, Shan; Dong, Zhongyun 2006. Adenovirus-mediated interferon-beta gene transfer inhibits angiogenesis in and progression of orthotopic tumors of human prostate cancer cells in nude mice. International journal of oncology, 29 6, 1405-12Lu, Shan; Dong, Zhongyun 2006. Characterization of TGF-beta-regulated interleukin-8 expression in human prostate cancer cells. The Prostate, 66 9, 996-1004Zhang, Fahao; Lee, Juwon; Wang, Daren; Dong, Zhongyun 2006. Differential growth of IFN-beta-engineered tumor cells in nude and IFN receptor-null mice. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 26 2, 108-18Liu, Guozhen; Zhang, Fahao; Lee, Juwon; Dong, Zhongyun 2005. Selective induction of interleukin-8 expression in metastatic melanoma cells by transforming growth factor-beta 1. Cytokine, 31 3, 241-9Uehara, Hisanori; Troncoso, Patricia; Johnston, Dennis; Bucana, Corazon D; Dinney, Colin; Dong, Zhongyun; Fidler, Isaiah J; Pettaway, Curtis A 2005. Expression of interleukin-8 gene in radical prostatectomy specimens is associated with advanced pathologic stage. The Prostate, 64 1, 40-9Zhang, Fahao; Lee, Juwon; Lu, Shan; Pettaway, Curtis A; Dong, Zhongyun 2005. Blockade of transforming growth factor-beta signaling suppresses progression of androgen-independent human prostate cancer in nude mice. Clinical cancer research : an official journal of the American Association for Cancer Research, 11 12, 4512-20Lu, Weixin; Su, Jindong; Kim, Lee Su; Bucana, Corazon D; Donawho, Cherrie; He, Junqing; Fidler, Isaiah J; Dong, Zhongyun 2003. Active specific immunotherapy against occult brain metastasis. Cancer research, 63 6, 1345-50Ozawa, Shutaro; Lu, Weixin; Bucana, Corazon D; Kanayama, Hiro-Omi; Shinohara, Hisashi; Fidler, Isaiah J; Dong, Zhongyun 2003. Regression of primary murine colon cancer and occult liver metastasis by intralesional injection of lyophilized preparation of insect cells producing murine interferon-beta. International journal of oncology, 22 5, 977-84Davies, Michael A; Kim, Sun J; Parikh, Nila U; Dong, Zhongyun; Bucana, Corazon D; Gallick, Gary E 2002. Adenoviral-mediated expression of MMAC/PTEN inhibits proliferation and metastasis of human prostate cancer cells. Clinical cancer research : an official journal of the American Association for Cancer Research, 8 6, 1904-14Harmey, Judith H; Bucana, Corazon D; Lu, Weixin; Byrne, Anne Marie; McDonnell, Susan; Lynch, Conor; Bouchier-Hayes, David; Dong, Zhongyun 2002. Lipopolysaccharide-induced metastatic growth is associated with increased angiogenesis, vascular permeability and tumor cell invasion. International journal of cancer. Journal international du cancer, 101 5, 415-22Izawa, Jonathan I; Sweeney, Paul; Perrotte, Paul; Kedar, Daniel; Dong, Zhongyun; Slaton, Joel W; Karashima, Takashi; Inoue, Keji; Benedict, William F; Dinney, Colin P N 2002. Inhibition of tumorigenicity and metastasis of human bladder cancer growing in athymic mice by interferon-beta gene therapy results partially from various antiangiogenic effects including endothelial cell apoptosis. Clinical cancer research : an official journal of the American Association for Cancer Research, 8 4, 1258-70Lu, Weixin; Dong, Zhongyun; Donawho, Cherrie; Fidler, Isaiah J 2002. Specific immunotherapy against occult cancer metastases. International journal of cancer. Journal international du cancer, 100 4, 480-5Makar, Tapas Kumar; Wilt, Susan; Dong, Zhongyun; Fishman, Paul; Mouradian, M Maral; Dhib-Jalbut, Suhayl 2002. IFN-beta gene transfer into the central nervous system using bone marrow cells as a delivery system. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 22 7, 783-91Takeuchi, Osamu; Sato, Shintaro; Horiuchi, Takao; Hoshino, Katsuaki; Takeda, Kiyoshi; Dong, Zhongyun; Modlin, Robert L; Akira, Shizuo 2002. Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins. 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