Trisha M. Wise-Draper, MD,PhD

Agresta, Laura; Lehn, Maria; Lampe, Kristin; Cantrell, Rachel; Hennies, Cassandra; Szabo, Sara; Wise-Draper, Trisha; Conforti, Laura; Hoebe, Kasper; Janssen, Edith M 2020. CD244 represents a new therapeutic target in head and neck squamous cell carcinoma. Journal for immunotherapy of cancer, 8 1,

Chimote, Ameet A; Gawali, Vaibhavkumar S; Newton, Hannah S; Wise-Draper, Trisha M; Conforti, Laura 2020. A Compartmentalized Reduction in Membrane-Proximal Calmodulin Reduces the Immune Surveillance Capabilities of CD8+ T Cells in Head and Neck Cancer. Frontiers in pharmacology, 11 , 143

Gulati, Shuchi; Desai, Janki; Palackdharry, Sarah M; Morris, John C; Zhu, Zheng; Jandarov, Roman; Riaz, Muhammad K; Takiar, Vinita; Mierzwa, Michelle; Gutkind, J Silvio; Molinolo, Alfredo; Desai, Pankaj B; Sadraei, Nooshin Hashemi; Wise-Draper, Trisha M 2020. Phase 1 dose-finding study of metformin in combination with concurrent cisplatin and radiotherapy in patients with locally advanced head and neck squamous cell cancer. Cancer, 126 2, 354-362

Tsurutani, Junji; Iwata, Hiroji; Krop, Ian; Jänne, Pasi A; Doi, Toshihiko; Takahashi, Shunji; Park, Haeseong; Redfern, Charles; Tamura, Kenji; Wise-Draper, Trisha M; Saito, Kaku; Sugihara, Masahiro; Singh, Jasmeet; Jikoh, Takahiro; Gallant, Gilles; Li, Bob T 2020. Targeting HER2 with Trastuzumab Deruxtecan: A Dose-Expansion, Phase I Study in Multiple Advanced Solid Tumors. Cancer discovery, ,

Haque, Sulsal; Karivedu, Vidhya; Riaz, Muhammed K; Choi, David; Roof, Logan; Hassan, Sarah Z; Zhu, Zheng; Jandarov, Roman; Takiar, Vinita; Tang, Alice; Wise-Draper, Trisha 2019. High-risk pathological features at the time of salvage surgery predict poor survival after definitive therapy in patients with head and neck squamous cell carcinoma. Oral oncology, 88 , 9-15

Kofuji, Satoshi; Hirayama, Akiyoshi; Eberhardt, Alexander Otto; Kawaguchi, Risa; Sugiura, Yuki; Sampetrean, Oltea; Ikeda, Yoshiki; Warren, Mikako; Sakamoto, Naoya; Kitahara, Shuji; Yoshino, Hirofumi; Yamashita, Daisuke; Sumita, Kazutaka; Wolfe, Kara; Lange, Lisa; Ikeda, Satsuki; Shimada, Hiroko; Minami, Noriaki; Malhotra, Akshiv; Morioka, Shin; Ban, Yuki; Asano, Maya; Flanary, Victoria L; Ramkissoon, Annmarie; Chow, Lionel M L; Kiyokawa, Juri; Mashimo, Tomoyuki; Lucey, Greg; Mareninov, Sergey; Ozawa, Tatsuya; Onishi, Nobuyuki; Okumura, Koichi; Terakawa, Jumpei; Daikoku, Takiko; Wise-Draper, Trisha; Majd, Nazanin; Kofuji, Kaori; Sasaki, Mika; Mori, Masaru; Kanemura, Yonehiro; Smith, Eric P; Anastasiou, Dimitrios; Wakimoto, Hiroaki; Holland, Eric C; Yong, William H; Horbinski, Craig; Nakano, Ichiro; DeBerardinis, Ralph J; Bachoo, Robert M; Mischel, Paul S; Yasui, Wataru; Suematsu, Makoto; Saya, Hideyuki; Soga, Tomoyoshi; Grummt, Ingrid; Bierhoff, Holger; Sasaki, Atsuo T 2019. IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma. Nature cell biology, 21 8, 1003-1014

Ribrag, Vincent; Avigan, David E; Green, Damian J; Wise-Draper, Trisha; Posada, Juan G; Vij, Ravi; Zhu, Ying; Farooqui, Mohammed Z H; Marinello, Patricia; Siegel, David S 2019. Phase 1b trial of pembrolizumab monotherapy for relapsed/refractory multiple myeloma: KEYNOTE-013. British journal of haematology, 186 3, e41-e44

Chimote, Ameet A; Balajthy, Andras; Arnold, Michael J; Newton, Hannah S; Hajdu, Peter; Qualtieri, Julianne; Wise-Draper, Trisha; Conforti, Laura 2018. A defect in KCa3.1 channel activity limits the ability of CD8+ T cells from cancer patients to infiltrate an adenosine-rich microenvironment. Science signaling, 11 527,

Haque, Sulsal-Ul; Niu, Liang; Kuhnell, Damaris; Hendershot, Jacob; Biesiada, Jacek; Niu, Wen; Hagan, Matthew C; Kelsey, Karl T; Casper, Keith A; Wise-Draper, Trisha M; Medvedovic, Mario; Langevin, Scott M 2018. Differential expression and prognostic value of long non-coding RNA in HPV-negative head and neck squamous cell carcinoma. Head & neck, 40 7, 1555-1564

Wise-Draper, Trisha; Sendilnathan, Arun; Palackdharry, Sarah; Pease, Nicholas; Qualtieri, Julianne; Butler, Randall; Sadraei, Nooshin Hashemi; Morris, John C; Patil, Yash; Wilson, Keith; Mark, Jonathan; Casper, Keith; Takiar, Vinita; Lane, Adam; Privette Vinnedge, Lisa 2018. Decreased plasma DEK Oncogene Levels Correlate with p16-Negative Disease and Advanced Tumor Stage in a Case-Control Study of Patients with Head and Neck Squamous Cell Carcinoma. Translational oncology, 11 1, 168-174

Chimote, Ameet A; Hajdu, Peter; Sfyris, Alexandros M; Gleich, Brittany N; Wise-Draper, Trisha; Casper, Keith A; Conforti, Laura 2017. Kv1.3 Channels Mark Functionally Competent CD8+ Tumor-Infiltrating Lymphocytes in Head and Neck Cancer. Cancer research, 77 1, 53-61

Langevin, Scott; Kuhnell, Damaris; Parry, Tess; Biesiada, Jacek; Huang, Shouxiong; Wise-Draper, Trisha; Casper, Keith; Zhang, Xiang; Medvedovic, Mario; Kasper, Susan 2017. Comprehensive microRNA-sequencing of exosomes derived from head and neck carcinoma cells in vitro reveals common secretion profiles and potential utility as salivary biomarkers. Oncotarget, 8 47, 82459-82474

Wise-Draper, Trisha M; Moorthy, Ganesh; Salkeni, Mohamad A; Karim, Nagla Abdel; Thomas, Hala Elnakat; Mercer, Carol A; Beg, M Shalaan; O'Gara, Sue; Olowokure, Olugbenga; Fathallah, Hassana; Kozma, Sara C; Thomas, George; Rixe, Olivier; Desai, Pankaj; Morris, John C 2017. A Phase Ib Study of the Dual PI3K/mTOR Inhibitor Dactolisib (BEZ235) Combined with Everolimus in Patients with Advanced Solid Malignancies. Targeted oncology, 12 3, 323-332

Old, Matthew O; Wise-Draper, Trisha; Wright, Chadwick L; Kaur, Balveen; Teknos, Theodoros 2016. The current status of oncolytic viral therapy for head and neck cancer. World journal of otorhinolaryngology - head and neck surgery, 2 2, 84-89

Riaz, Muhammad Kashif; Bal, Susan; Wise-Draper, Trisha 2016. The impending financial healthcare burden and ethical dilemma of systemic therapy in metastatic cancer. Journal of surgical oncology, ,

Adams, A K; Hallenbeck, G E; Casper, K A; Patil, Y J; Wilson, K M; Kimple, R J; Lambert, P F; Witte, D P; Xiao, W; Gillison, M L; Wikenheiser-Brokamp, K A; Wise-Draper, T M; Wells, S I 2015. DEK promotes HPV-positive and -negative head and neck cancer cell proliferation. Oncogene, 34 7, 868-77

Malhotra, Akshiv; Sendilnathan, Arun; Old, Matthew O; Wise-Draper, Trisha M 2015. Oncolytic virotherapy for head and neck cancer: current research and future developments. Oncolytic virotherapy, 4 , 83-93

Pease, Nicholas A; Wise-Draper, Trisha; Privette Vinnedge, Lisa 2015. Dissecting the Potential Interplay of DEK Functions in Inflammation and Cancer. Journal of oncology, 2015 , 106517

Adams, Allie K; Wise-Draper, Trisha M; Wells, Susanne I 2014. Human papillomavirus induced transformation in cervical and head and neck cancers. Cancers, 6 3, 1793-820

Ghose, Abhimanyu; Yellu, Mahender; Wise-Draper, Trisha; Sharma, Divya; Qualtieri, Julianne; Latif, Tahir; Medlin, Stephen 2014. Lymphoma presenting as secondary HLH: a review with a tale of two cases. Clinical lymphoma, myeloma & leukemia, 14 6, e187-93

Bahassi, El Mustapha; Li, Ya-Qin; Wise-Draper, Trisha M; Deng, Li; Wang, Jiang; Darnell, Colleen N; Wilson, Keith M; Wells, Susanne I; Stambrook, Peter J; Rixe, Olivier 2013. A patient-derived somatic mutation in the epidermal growth factor receptor ligand-binding domain confers increased sensitivity to cetuximab in head and neck cancer. European journal of cancer (Oxford, England : 1990), 49 10, 2345-55

Wise-Draper, Trisha M; Draper, David J; Gutkind, J Silvio; Molinolo, Alfredo A; Wikenheiser-Brokamp, Kathryn A; Wells, Susanne I 2012. Future directions and treatment strategies for head and neck squamous cell carcinomas. Translational research : the journal of laboratory and clinical medicine, 160 3, 167-77

Kavanaugh, Gina M; Wise-Draper, Trisha M; Morreale, Richard J; Morrison, Monique A; Gole, Boris; Schwemberger, Sandy; Tichy, Elisia D; Lu, Lu; Babcock, George F; Wells, James M; Drissi, Rachid; Bissler, John J; Stambrook, Peter J; Andreassen, Paul R; Wiesmüller, Lisa; Wells, Susanne I 2011. The human DEK oncogene regulates DNA damage response signaling and repair. Nucleic acids research, 39 17, 7465-76

Wise-Draper, Trisha M; Mintz-Cole, Rachael A; Morris, Teresa A; Simpson, David S; Wikenheiser-Brokamp, Kathryn A; Currier, Mark A; Cripe, Timothy P; Grosveld, Gerard C; Wells, Susanne I 2009. Overexpression of the cellular DEK protein promotes epithelial transformation in vitro and in vivo. Cancer research, 69 5, 1792-9

Wise-Draper, Trisha M; Morreale, Richard J; Morris, Teresa A; Mintz-Cole, Rachael A; Hoskins, Elizabeth E; Balsitis, Scott J; Husseinzadeh, Nader; Witte, David P; Wikenheiser-Brokamp, Kathryn A; Lambert, Paul F; Wells, Susanne I 2009. DEK proto-oncogene expression interferes with the normal epithelial differentiation program. The American journal of pathology, 174 1, 71-81

Hoskins, E E; Gunawardena, R W; Habash, K B; Wise-Draper, T M; Jansen, M; Knudsen, E S; Wells, S I 2008. Coordinate regulation of Fanconi anemia gene expression occurs through the Rb/E2F pathway. Oncogene, 27 35, 4798-808

Wise-Draper, Trisha M; Wells, Susanne I 2008. Papillomavirus E6 and E7 proteins and their cellular targets. Frontiers in bioscience : a journal and virtual library, 13 , 1003-17

Wise-Draper, Trisha M; Allen, Hillary V; Jones, Elizabeth E; Habash, Kristen B; Matsuo, Hiroshi; Wells, Susanne I 2006. Apoptosis inhibition by the human DEK oncoprotein involves interference with p53 functions. Molecular and cellular biology, 26 20, 7506-19

Wise-Draper, Trisha M; Allen, Hillary V; Thobe, Megan N; Jones, Elizabeth E; Habash, Kristen B; Münger, Karl; Wells, Susanne I 2005. The human DEK proto-oncogene is a senescence inhibitor and an upregulated target of high-risk human papillomavirus E7. Journal of virology, 79 22, 14309-17

Brana I.; Cohen E.E.W.; Cook C.E.; Harrington K.J.; Hong D.S.; Keilholz U.; McCoon P.; Mehta M.; Mesia R.; Mitchell P.D.; Mugundu G.M.; Perez Segura P.; Scott M.L.; Wise-Draper T. 10-01-2018. A phase Ib/II study (SCORES) of durvalumab (D) plus danvatirsen (DAN; AZD9150) or AZD5069 (CX2i) in Annals of oncology : official journal of the European Society for Medical Oncology, 29 , viii372

Adams A.;Wise-Draper T.;Wells S. 09-15-2014. Human papillomavirus induced transformation in cervical and head and neck cancers Cancers, 6 3, 1793-1820

Wells S.;Aronow B.;Wise T.;Williams S.;Couget J.;Howley P. 06-10-2003. Transcriptome signature of irreversible senescence in human papillomavirus-positive cervical cancer Proceedings of the National Academy of Sciences of the United States of America, 100 12, 7093-7098

Wise-Draper T.;Wells S. 03-01-2005. Efficient transfection of siRNA against HPV oncogenes BioSpektrum, 11 1, 107-108

Chimote A.A.;Gawali V.S.;Newton H.S.;Wise-Draper T.M.;Conforti L. 02-28-2020. A Compartmentalized Reduction in Membrane-Proximal Calmodulin Reduces the Immune Surveillance Capabi Frontiers in Pharmacology, 11 ,

Wise-Draper T.;Sendilnathan A.;Palackdharry S.;Pease N.;Qualtieri J.;Butler R.;Sadraei N.;Morris J.;Patil Y.;Wilson K.;Mark J.;Casper K.;Takiar V.;Lane A.;Privette Vinnedge L. 01-01-2018. Decreased plasma DEK Oncogene Levels Correlate with p16-Negative Disease and Advanced Tumor Stage in Translational Oncology, 11 1, 168-174

Langevin S.;Kuhnell D.;Parry T.;Biesiada J.;Huang S.;Wise-Draper T.;Casper K.;Zhang X.;Medvedovic M.;Kasper S. 01-01-2017. Comprehensive microRNA-sequencing of exosomes derived from head and neck carcinoma cells in vitro re Oncotarget, 8 47, 82459-82474

Pease N.;Wise-Draper T.;Privette Vinnedge L. 01-01-2015. Dissecting the Potential Interplay of DEK Functions in Inflammation and Cancer Journal of Oncology, 2015 ,

Wise-Draper T.M.;Draper D.J.;Gutkind J.S.;Molinolo A.A.;Wikenheiser-Brokamp K.A.;Wells S.I. 01-01-2012. Future directions and treatment strategies for head and neck squamous cell carcinomas Translational Research, 160 3, 167-177

Adams, A.K., Hallenbeck, G.E., Casper, K.A., Patil, Y.J., Wilson, K.M., Kimple, R.J., Lambert, P.F., Witte, D.P., Xiao, W., Gillison, M.L., Wise-Draper T.M., and Wikenheiser-Brokamp, K.A. 2015. DEK promotes HPV-positive and-negative head and neck cancer cell proliferation Oncogene, 34(7) , 868

Pease, N.A., Wise-Draper, T. and Privette Vinnedge, L. 2015. Dissecting the Potential Interplay of DEK Functions in Inflammation and Cancer Journal of oncology, ,

Wise-Draper, T.M., Mintz-Cole, R.A., Morris, T.A., Simpson, D.S., Wikenheiser-Brokamp, K.A., Currier, M.A., Cripe, T.P., Grosveld, G.C. and Wells, S.I. 2009. Overexpression of the cellular DEK protein promotes epithelial transformation in vitro and in vivo Cancer research, 69(5) , 1792