Education/CredentialsM.D.: Weill Cornell Medical CollegePh.D.: The Rockefeller University (Cell Biology/Genetics)S.B.: Massachusetts Institute of Technology (Chemistry, Biology, Literature (minor)) Contact Information Childrens Hospital Bldg R Office 513-636-4200 Email wupv@ucmail.uc.edu Peer Reviewed Publications Bouju, Agathe; Nusse, Roel; Wu, Peng V 2024. A primer on the pleiotropic endocrine fibroblast growth factor FGF19/FGF15. Differentiation; research in biological diversity, , 100816Wu, Peng V; Fish, Matt; Hazard, Florette K; Zhu, Chunfang; Vennam, Sujay; Walton, Hannah; Wagh, Dhananjay; Coller, John; Przybyl, Joanna; Morri, Maurizio; Neff, Norma; West, Robert B; Nusse, Roel 2024. A developmental biliary lineage program cooperates with Wnt activation to promote cell proliferation in hepatoblastoma. Nature communications, 15 1, 10007Myler, Logan R; Toia, Beatrice; Vaughan, Cara K; Takai, Kaori; Matei, Andreea M; Wu, Peng; Paull, Tanya T; de Lange, Titia; Lottersberger, Francisca 2023. DNA-PK and the TRF2 iDDR inhibit MRN-initiated resection at leading-end telomeres. Nature structural & molecular biology, 30 9, 1346-1356Sarkar, Abby; Jin, Yinhua; DeFelice, Brian C; Logan, Catriona Y; Yang, Yan; Anbarchian, Teni; Wu, Peng; Morri, Maurizio; Neff, Norma F; Nguyen, Huy; Rulifson, Eric; Fish, Matthew; Kaye, Avi Gurion; Martínez Jaimes, Azalia M; Nusse, Roel 2023. Intermittent fasting induces rapid hepatocyte proliferation to restore the hepatostat in the mouse liver. eLife, 12 , Jin, Yinhua; Anbarchian, Teni; Wu, Peng; Sarkar, Abby; Fish, Matt; Peng, Weng Chuan; Nusse, Roel 2022. Wnt signaling regulates hepatocyte cell division by a transcriptional repressor cascade. Proceedings of the National Academy of Sciences of the United States of America, 119 30, e2203849119Wu, Peng V; Nusse, Roel 2022. 3D Culture of Primary Patient-Derived Hepatoblastoma Tumoroids. Methods in molecular biology (Clifton, N.J.), 2544 , 259-267Wu, Peng V; Rangaswami, Arun 2022. Current Approaches in Hepatoblastoma-New Biological Insights to Inform Therapy. Current oncology reports, 24 9, 1209-1218Peng, Weng Chuan; Logan, Catriona Y; Fish, Matt; Anbarchian, Teni; Aguisanda, Francis; Álvarez-Varela, Adrián; Wu, Peng; Jin, Yinhua; Zhu, Junjie; Li, Bin; Grompe, Markus; Wang, Bruce; Nusse, Roel 2018. Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture. Cell, 175 6, 1607-1619.e15Wu, Peng; Takai, Hiroyuki; de Lange, Titia 2012. Telomeric 3' overhangs derive from resection by Exo1 and Apollo and fill-in by POT1b-associated CST. Cell, 150 1, 39-52Wu, Peng; van Overbeek, Megan; Rooney, Sean; de Lange, Titia 2010. Apollo contributes to G overhang maintenance and protects leading-end telomeres. Molecular cell, 39 4, 606-17Wu, Peng; de Lange, Titia 2009. Human telomerase caught in the act. Cell, 138 3, 432-4Wu, Peng; de Lange, Titia 2008. No overt nucleosome eviction at deprotected telomeres. Molecular and cellular biology, 28 18, 5724-35
Peer Reviewed Publications Bouju, Agathe; Nusse, Roel; Wu, Peng V 2024. A primer on the pleiotropic endocrine fibroblast growth factor FGF19/FGF15. Differentiation; research in biological diversity, , 100816Wu, Peng V; Fish, Matt; Hazard, Florette K; Zhu, Chunfang; Vennam, Sujay; Walton, Hannah; Wagh, Dhananjay; Coller, John; Przybyl, Joanna; Morri, Maurizio; Neff, Norma; West, Robert B; Nusse, Roel 2024. A developmental biliary lineage program cooperates with Wnt activation to promote cell proliferation in hepatoblastoma. Nature communications, 15 1, 10007Myler, Logan R; Toia, Beatrice; Vaughan, Cara K; Takai, Kaori; Matei, Andreea M; Wu, Peng; Paull, Tanya T; de Lange, Titia; Lottersberger, Francisca 2023. DNA-PK and the TRF2 iDDR inhibit MRN-initiated resection at leading-end telomeres. Nature structural & molecular biology, 30 9, 1346-1356Sarkar, Abby; Jin, Yinhua; DeFelice, Brian C; Logan, Catriona Y; Yang, Yan; Anbarchian, Teni; Wu, Peng; Morri, Maurizio; Neff, Norma F; Nguyen, Huy; Rulifson, Eric; Fish, Matthew; Kaye, Avi Gurion; Martínez Jaimes, Azalia M; Nusse, Roel 2023. Intermittent fasting induces rapid hepatocyte proliferation to restore the hepatostat in the mouse liver. eLife, 12 , Jin, Yinhua; Anbarchian, Teni; Wu, Peng; Sarkar, Abby; Fish, Matt; Peng, Weng Chuan; Nusse, Roel 2022. Wnt signaling regulates hepatocyte cell division by a transcriptional repressor cascade. Proceedings of the National Academy of Sciences of the United States of America, 119 30, e2203849119Wu, Peng V; Nusse, Roel 2022. 3D Culture of Primary Patient-Derived Hepatoblastoma Tumoroids. Methods in molecular biology (Clifton, N.J.), 2544 , 259-267Wu, Peng V; Rangaswami, Arun 2022. Current Approaches in Hepatoblastoma-New Biological Insights to Inform Therapy. Current oncology reports, 24 9, 1209-1218Peng, Weng Chuan; Logan, Catriona Y; Fish, Matt; Anbarchian, Teni; Aguisanda, Francis; Álvarez-Varela, Adrián; Wu, Peng; Jin, Yinhua; Zhu, Junjie; Li, Bin; Grompe, Markus; Wang, Bruce; Nusse, Roel 2018. Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture. Cell, 175 6, 1607-1619.e15Wu, Peng; Takai, Hiroyuki; de Lange, Titia 2012. Telomeric 3' overhangs derive from resection by Exo1 and Apollo and fill-in by POT1b-associated CST. Cell, 150 1, 39-52Wu, Peng; van Overbeek, Megan; Rooney, Sean; de Lange, Titia 2010. Apollo contributes to G overhang maintenance and protects leading-end telomeres. Molecular cell, 39 4, 606-17Wu, Peng; de Lange, Titia 2009. Human telomerase caught in the act. Cell, 138 3, 432-4Wu, Peng; de Lange, Titia 2008. No overt nucleosome eviction at deprotected telomeres. Molecular and cellular biology, 28 18, 5724-35
Bouju, Agathe; Nusse, Roel; Wu, Peng V 2024. A primer on the pleiotropic endocrine fibroblast growth factor FGF19/FGF15. Differentiation; research in biological diversity, , 100816Wu, Peng V; Fish, Matt; Hazard, Florette K; Zhu, Chunfang; Vennam, Sujay; Walton, Hannah; Wagh, Dhananjay; Coller, John; Przybyl, Joanna; Morri, Maurizio; Neff, Norma; West, Robert B; Nusse, Roel 2024. A developmental biliary lineage program cooperates with Wnt activation to promote cell proliferation in hepatoblastoma. Nature communications, 15 1, 10007Myler, Logan R; Toia, Beatrice; Vaughan, Cara K; Takai, Kaori; Matei, Andreea M; Wu, Peng; Paull, Tanya T; de Lange, Titia; Lottersberger, Francisca 2023. DNA-PK and the TRF2 iDDR inhibit MRN-initiated resection at leading-end telomeres. Nature structural & molecular biology, 30 9, 1346-1356Sarkar, Abby; Jin, Yinhua; DeFelice, Brian C; Logan, Catriona Y; Yang, Yan; Anbarchian, Teni; Wu, Peng; Morri, Maurizio; Neff, Norma F; Nguyen, Huy; Rulifson, Eric; Fish, Matthew; Kaye, Avi Gurion; Martínez Jaimes, Azalia M; Nusse, Roel 2023. Intermittent fasting induces rapid hepatocyte proliferation to restore the hepatostat in the mouse liver. eLife, 12 , Jin, Yinhua; Anbarchian, Teni; Wu, Peng; Sarkar, Abby; Fish, Matt; Peng, Weng Chuan; Nusse, Roel 2022. Wnt signaling regulates hepatocyte cell division by a transcriptional repressor cascade. Proceedings of the National Academy of Sciences of the United States of America, 119 30, e2203849119Wu, Peng V; Nusse, Roel 2022. 3D Culture of Primary Patient-Derived Hepatoblastoma Tumoroids. Methods in molecular biology (Clifton, N.J.), 2544 , 259-267Wu, Peng V; Rangaswami, Arun 2022. Current Approaches in Hepatoblastoma-New Biological Insights to Inform Therapy. Current oncology reports, 24 9, 1209-1218Peng, Weng Chuan; Logan, Catriona Y; Fish, Matt; Anbarchian, Teni; Aguisanda, Francis; Álvarez-Varela, Adrián; Wu, Peng; Jin, Yinhua; Zhu, Junjie; Li, Bin; Grompe, Markus; Wang, Bruce; Nusse, Roel 2018. Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture. Cell, 175 6, 1607-1619.e15Wu, Peng; Takai, Hiroyuki; de Lange, Titia 2012. Telomeric 3' overhangs derive from resection by Exo1 and Apollo and fill-in by POT1b-associated CST. Cell, 150 1, 39-52Wu, Peng; van Overbeek, Megan; Rooney, Sean; de Lange, Titia 2010. Apollo contributes to G overhang maintenance and protects leading-end telomeres. Molecular cell, 39 4, 606-17Wu, Peng; de Lange, Titia 2009. Human telomerase caught in the act. Cell, 138 3, 432-4Wu, Peng; de Lange, Titia 2008. No overt nucleosome eviction at deprotected telomeres. Molecular and cellular biology, 28 18, 5724-35