Contact Information Email streetse@ucmail.uc.edu Peer Reviewed Publications Díaz Ludovico, Ivo; Gonzalez, Marina C; Garda, Horacio A; Vázquez, Romina F; Maté, Sabina; Tricerri, María A; Ramella, Nahuel A; Bedi, Shimpi; Morris, Jamie; Street, Scott E; Geh, Esmond; Clair, Geremy C; Davidson, W Sean; Melchior, John T 2025. The congenital APOA1 K107del mutation disrupts the lipid-free conformation of monomeric APOA1 and impairs oligomerization. Journal of lipid research, 66 12, 100929Geh, Esmond N; Swertfeger, Debi K; Roscoe, Isabella; Street, Scott E; Bursey, Alexiana; Sexmith, Hannah; Woollett, Laura A; Davidson, W Sean; Shah, Amy Sanghavi 2025. Exchangeable APOA1 on HDL inhibits LDL binding to proteoglycans. Journal of lipid research, 66 9, 100885Sarkar, Snigdha; Morris, Jamie; You, Youngki; Sexmith, Hannah; Street, Scott E; Thibert, Stephanie M; Attah, Isaac K; Hutchinson Bunch, Chelsea M; Novikova, Irina V; Evans, James E; Shah, Amy S; Gordon, Scott M; Segrest, Jere P; Bornfeldt, Karin E; Vaisar, Tomas; Heinecke, Jay W; Davidson, W Sean; Melchior, John T 2024. APOA2 increases cholesterol efflux capacity to plasma HDL by displacing the C-terminus of resident APOA1. Journal of lipid research, 65 12, 100686Atehortua, Laura; Morris, Jamie; Street, Scott E; Bedel, Nicholas; Davidson, W Sean; Chougnet, Claire A 2023. Apolipoprotein E-containing HDL decreases caspase-dependent apoptosis of memory regulatory T lymphocytes. Journal of lipid research, 64 9, 100425Whitacre, Brynne E; Howles, Philip; Street, Scott; Morris, Jamie; Swertfeger, Debi; Davidson, W Sean 2022. Apolipoprotein E content of VLDL limits LPL-mediated triglyceride hydrolysis. Journal of lipid research, 63 1, 100157Melchior, John T; Street, Scott E; Vaisar, Tomas; Hart, Rachel; Jerome, Jay; Kuklenyik, Zsuzsanna; Clouet-Foraison, Noemie; Thornock, Carissa; Bedi, Shimpi; Shah, Amy S; Segrest, Jere P; Heinecke, Jay W; Davidson, W Sean 2021. Apolipoprotein A-I modulates HDL particle size in the absence of apolipoprotein A-II. Journal of lipid research, 62 , 100099Melchior, John T; Swertfeger, Debi K; Morris, Jamie; Street, Scott E; Warshak, Carri R; Welge, Jeffrey A; Remaley, Alan T; Catov, Janet M; Davidson, W Sean; Woollett, Laura A 2021. Pregnancy is accompanied by larger high density lipoprotein particles and compositionally distinct subspecies. Journal of lipid research, 62 , 100107Cooke, Allison L; Morris, Jamie; Melchior, John T; Street, Scott E; Jerome, W Gray; Huang, Rong; Herr, Andrew B; Smith, Loren E; Segrest, Jere P; Remaley, Alan T; Shah, Amy S; Thompson, Thomas B; Davidson, W Sean 2018. A thumbwheel mechanism for APOA1 activation of LCAT activity in HDL. Journal of lipid research, 59 7, 1244-1255Melchior, John T; Street, Scott E; Andraski, Allison B; Furtado, Jeremy D; Sacks, Frank M; Shute, Rebecca L; Greve, Emily I; Swertfeger, Debi K; Li, Hailong; Shah, Amy S; Lu, L Jason; Davidson, W Sean 2017. Apolipoprotein A-II alters the proteome of human lipoproteins and enhances cholesterol efflux from ABCA1. Journal of lipid research, 58 7, 1374-1385
Peer Reviewed Publications Díaz Ludovico, Ivo; Gonzalez, Marina C; Garda, Horacio A; Vázquez, Romina F; Maté, Sabina; Tricerri, María A; Ramella, Nahuel A; Bedi, Shimpi; Morris, Jamie; Street, Scott E; Geh, Esmond; Clair, Geremy C; Davidson, W Sean; Melchior, John T 2025. The congenital APOA1 K107del mutation disrupts the lipid-free conformation of monomeric APOA1 and impairs oligomerization. Journal of lipid research, 66 12, 100929Geh, Esmond N; Swertfeger, Debi K; Roscoe, Isabella; Street, Scott E; Bursey, Alexiana; Sexmith, Hannah; Woollett, Laura A; Davidson, W Sean; Shah, Amy Sanghavi 2025. Exchangeable APOA1 on HDL inhibits LDL binding to proteoglycans. Journal of lipid research, 66 9, 100885Sarkar, Snigdha; Morris, Jamie; You, Youngki; Sexmith, Hannah; Street, Scott E; Thibert, Stephanie M; Attah, Isaac K; Hutchinson Bunch, Chelsea M; Novikova, Irina V; Evans, James E; Shah, Amy S; Gordon, Scott M; Segrest, Jere P; Bornfeldt, Karin E; Vaisar, Tomas; Heinecke, Jay W; Davidson, W Sean; Melchior, John T 2024. APOA2 increases cholesterol efflux capacity to plasma HDL by displacing the C-terminus of resident APOA1. Journal of lipid research, 65 12, 100686Atehortua, Laura; Morris, Jamie; Street, Scott E; Bedel, Nicholas; Davidson, W Sean; Chougnet, Claire A 2023. Apolipoprotein E-containing HDL decreases caspase-dependent apoptosis of memory regulatory T lymphocytes. Journal of lipid research, 64 9, 100425Whitacre, Brynne E; Howles, Philip; Street, Scott; Morris, Jamie; Swertfeger, Debi; Davidson, W Sean 2022. Apolipoprotein E content of VLDL limits LPL-mediated triglyceride hydrolysis. Journal of lipid research, 63 1, 100157Melchior, John T; Street, Scott E; Vaisar, Tomas; Hart, Rachel; Jerome, Jay; Kuklenyik, Zsuzsanna; Clouet-Foraison, Noemie; Thornock, Carissa; Bedi, Shimpi; Shah, Amy S; Segrest, Jere P; Heinecke, Jay W; Davidson, W Sean 2021. Apolipoprotein A-I modulates HDL particle size in the absence of apolipoprotein A-II. Journal of lipid research, 62 , 100099Melchior, John T; Swertfeger, Debi K; Morris, Jamie; Street, Scott E; Warshak, Carri R; Welge, Jeffrey A; Remaley, Alan T; Catov, Janet M; Davidson, W Sean; Woollett, Laura A 2021. Pregnancy is accompanied by larger high density lipoprotein particles and compositionally distinct subspecies. Journal of lipid research, 62 , 100107Cooke, Allison L; Morris, Jamie; Melchior, John T; Street, Scott E; Jerome, W Gray; Huang, Rong; Herr, Andrew B; Smith, Loren E; Segrest, Jere P; Remaley, Alan T; Shah, Amy S; Thompson, Thomas B; Davidson, W Sean 2018. A thumbwheel mechanism for APOA1 activation of LCAT activity in HDL. Journal of lipid research, 59 7, 1244-1255Melchior, John T; Street, Scott E; Andraski, Allison B; Furtado, Jeremy D; Sacks, Frank M; Shute, Rebecca L; Greve, Emily I; Swertfeger, Debi K; Li, Hailong; Shah, Amy S; Lu, L Jason; Davidson, W Sean 2017. Apolipoprotein A-II alters the proteome of human lipoproteins and enhances cholesterol efflux from ABCA1. Journal of lipid research, 58 7, 1374-1385
Díaz Ludovico, Ivo; Gonzalez, Marina C; Garda, Horacio A; Vázquez, Romina F; Maté, Sabina; Tricerri, María A; Ramella, Nahuel A; Bedi, Shimpi; Morris, Jamie; Street, Scott E; Geh, Esmond; Clair, Geremy C; Davidson, W Sean; Melchior, John T 2025. The congenital APOA1 K107del mutation disrupts the lipid-free conformation of monomeric APOA1 and impairs oligomerization. Journal of lipid research, 66 12, 100929Geh, Esmond N; Swertfeger, Debi K; Roscoe, Isabella; Street, Scott E; Bursey, Alexiana; Sexmith, Hannah; Woollett, Laura A; Davidson, W Sean; Shah, Amy Sanghavi 2025. Exchangeable APOA1 on HDL inhibits LDL binding to proteoglycans. Journal of lipid research, 66 9, 100885Sarkar, Snigdha; Morris, Jamie; You, Youngki; Sexmith, Hannah; Street, Scott E; Thibert, Stephanie M; Attah, Isaac K; Hutchinson Bunch, Chelsea M; Novikova, Irina V; Evans, James E; Shah, Amy S; Gordon, Scott M; Segrest, Jere P; Bornfeldt, Karin E; Vaisar, Tomas; Heinecke, Jay W; Davidson, W Sean; Melchior, John T 2024. APOA2 increases cholesterol efflux capacity to plasma HDL by displacing the C-terminus of resident APOA1. Journal of lipid research, 65 12, 100686Atehortua, Laura; Morris, Jamie; Street, Scott E; Bedel, Nicholas; Davidson, W Sean; Chougnet, Claire A 2023. Apolipoprotein E-containing HDL decreases caspase-dependent apoptosis of memory regulatory T lymphocytes. Journal of lipid research, 64 9, 100425Whitacre, Brynne E; Howles, Philip; Street, Scott; Morris, Jamie; Swertfeger, Debi; Davidson, W Sean 2022. Apolipoprotein E content of VLDL limits LPL-mediated triglyceride hydrolysis. Journal of lipid research, 63 1, 100157Melchior, John T; Street, Scott E; Vaisar, Tomas; Hart, Rachel; Jerome, Jay; Kuklenyik, Zsuzsanna; Clouet-Foraison, Noemie; Thornock, Carissa; Bedi, Shimpi; Shah, Amy S; Segrest, Jere P; Heinecke, Jay W; Davidson, W Sean 2021. Apolipoprotein A-I modulates HDL particle size in the absence of apolipoprotein A-II. Journal of lipid research, 62 , 100099Melchior, John T; Swertfeger, Debi K; Morris, Jamie; Street, Scott E; Warshak, Carri R; Welge, Jeffrey A; Remaley, Alan T; Catov, Janet M; Davidson, W Sean; Woollett, Laura A 2021. Pregnancy is accompanied by larger high density lipoprotein particles and compositionally distinct subspecies. Journal of lipid research, 62 , 100107Cooke, Allison L; Morris, Jamie; Melchior, John T; Street, Scott E; Jerome, W Gray; Huang, Rong; Herr, Andrew B; Smith, Loren E; Segrest, Jere P; Remaley, Alan T; Shah, Amy S; Thompson, Thomas B; Davidson, W Sean 2018. A thumbwheel mechanism for APOA1 activation of LCAT activity in HDL. Journal of lipid research, 59 7, 1244-1255Melchior, John T; Street, Scott E; Andraski, Allison B; Furtado, Jeremy D; Sacks, Frank M; Shute, Rebecca L; Greve, Emily I; Swertfeger, Debi K; Li, Hailong; Shah, Amy S; Lu, L Jason; Davidson, W Sean 2017. Apolipoprotein A-II alters the proteome of human lipoproteins and enhances cholesterol efflux from ABCA1. Journal of lipid research, 58 7, 1374-1385