Education/CredentialsPhD: Jawahar Lal University (Molecular and Cell Biology)MSc: Utkal University (Botany (specialization-Plant Biochemistry))BSc: Utkal University (Botany (Hons), Zoology, Chemistry) Contact Information Hoxworth Center (4-5) Office 513-415-9604 Email nayakrh@ucmail.uc.edu Peer Reviewed Publications Menéndez-Gutiérrez, María Piedad; Porcuna, Jesús; Nayak, Ramesh; Paredes, Ana; Niu, Haixia; Núñez, Vanessa; Paranjpe, Aditi; Gómez, Manuel J; Bhattacharjee, Anukana; Schnell, Daniel J; Sánchez-Cabo, Fátima; Welch, John S; Salomonis, Nathan; Cancelas, Jose A; Ricote, Mercedes 2023. Retinoid X receptor promotes hematopoietic stem cell fitness and quiescence and preserves hematopoietic homeostasis. Blood, 141 6, 592-608Nayak, R C; Chang, K H; Singh, A K; Kotliar, M; Desai, M; Wellendorf, A M; Wunderlich, M; Bartram, J; Mizukawa, B; Cuadrado, M; Dexheimer, P; Barski, A; Bustelo, X R; Nassar, N N; Cancelas, J A 2022. Nuclear Vav3 is required for polycomb repression complex-1 activity in B-cell lymphoblastic leukemogenesis. Nature communications, 13 1, 3056Althoff, Mark J; Nayak, Ramesh C; Hegde, Shailaja; Wellendorf, Ashley M; Bohan, Breanna; Filippi, Marie-Dominique; Xin, Mei; Lu, Q Richard; Geiger, Hartmut; Zheng, Yi; Diaz-Meco, Maria T; Moscat, Jorge; Cancelas, Jose A 2020. Yap1-Scribble polarization is required for hematopoietic stem cell division and fate. Blood, 136 16, 1824-1836Govindarajah, Vinothini; Lee, Jung-Mi; Solomon, Michael; Goddard, Bryan; Nayak, Ramesh; Nattamai, Kalpana; Geiger, Hartmut; Salomonis, Nathan; Cancelas, Jose A; Reynaud, Damien 2020. FOXO activity adaptation safeguards the hematopoietic stem cell compartment in hyperglycemia. Blood advances, 4 21, 5512-5526Nayak, R C; Hegde, S; Althoff, M J; Wellendorf, A M; Mohmoud, F; Perentesis, J; Reina-Campos, M; Reynaud, D; Zheng, Y; Diaz-Meco, M T; Moscat, J; Cancelas, J A 2019. The signaling axis atypical protein kinase C λ/ι-Satb2 mediates leukemic transformation of B-cell progenitors. Nature communications, 10 1, 46Nayak, Ramesh C; Cancelas, Jose A 2019. Ubiquitination is not omnipresent in myeloid leukemia. Haematologica, 104 9, 1694-1696Trump, Lisa R; Nayak, Ramesh C; Singh, Abhishek K; Emberesh, Sana; Wellendorf, Ashley M; Lutzko, Carolyn M; Cancelas, Jose A 2019. Neutrophils Derived from Genetically Modified Human Induced Pluripotent Stem Cells Circulate and Phagocytose Bacteria In Vivo. Stem cells translational medicine, 8 6, 557-567Liu, Shutong; de Castro, Luis F; Jin, Ping; Civini, Sara; Ren, Jiaqiang; Reems, Jo-Anna; Cancelas, Jose; Nayak, Ramesh; Shaw, Georgina; O'Brien, Timothy; McKenna, David H; Armant, Myriam; Silberstein, Leslie; Gee, Adrian P; Hei, Derek J; Hematti, Peiman; Kuznetsov, Sergei A; Robey, Pamela G; Stroncek, David F 2017. Manufacturing Differences Affect Human Bone Marrow Stromal Cell Characteristics and Function: Comparison of Production Methods and Products from Multiple Centers. Scientific reports, 7 , 46731Chang, Kyung Hee; Nayak, Ramesh C; Roy, Swarnava; Perumbeti, Ajay; Wellendorf, Ashley M; Bezold, Katie Y; Pirman, Megan; Hill, Sarah E; Starnes, Joseph; Loberg, Anastacia; Zhou, Xuan; Inagami, Tadashi; Zheng, Yi; Malik, Punam; Cancelas, Jose A 2015. Vasculopathy-associated hyperangiotensinemia mobilizes haematopoietic stem cells/progenitors through endothelial AT₂R and cytoskeletal dysregulation. Nature communications, 6 , 5914Nayak, Ramesh C; Trump, Lisa R; Aronow, Bruce J; Myers, Kasiani; Mehta, Parinda; Kalfa, Theodosia; Wellendorf, Ashley M; Valencia, C Alexander; Paddison, Patrick J; Horwitz, Marshall S; Grimes, H Leighton; Lutzko, Carolyn; Cancelas, Jose A 2015. Pathogenesis of ELANE-mutant severe neutropenia revealed by induced pluripotent stem cells. The Journal of clinical investigation, 125 8, 3103-16Chang, Kyung Hee; Sengupta, Amitava; Nayak, Ramesh C; Duran, Angeles; Lee, Sang Jun; Pratt, Ronald G; Wellendorf, Ashley M; Hill, Sarah E; Watkins, Marcus; Gonzalez-Nieto, Daniel; Aronow, Bruce J; Starczynowski, Daniel T; Civitelli, Roberto; Diaz-Meco, Maria T; Moscat, Jorge; Cancelas, Jose A 2014. p62 is required for stem cell/progenitor retention through inhibition of IKK/NF-κB/Ccl4 signaling at the bone marrow macrophage-osteoblast niche. Cell reports, 9 6, 2084-97Tidwell, Timothy; Wechsler, Jeremy; Nayak, Ramesh C; Trump, Lisa; Salipante, Stephen J; Cheng, Jerry C; Donadieu, Jean; Glaubach, Taly; Corey, Seth J; Grimes, H Leighton; Lutzko, Carolyn; Cancelas, Jose A; Horwitz, Marshall S 2014. Neutropenia-associated ELANE mutations disrupting translation initiation produce novel neutrophil elastase isoforms. Blood, 123 4, 562-9Nayak, Ramesh C; Chang, Kyung-Hee; Vaitinadin, Nataraja-Sarma; Cancelas, Jose A 2013. Rho GTPases control specific cytoskeleton-dependent functions of hematopoietic stem cells. Immunological reviews, 256 1, 255-68Nayak, Ramesh C; Keshava, Shiva; Esmon, Charles T; Pendurthi, Usha R; Rao, L Vijaya Mohan 2013. Rab GTPases regulate endothelial cell protein C receptor-mediated endocytosis and trafficking of factor VIIa. PloS one, 8 3, e59304Raman, R; Kumar, R S; Hinge, A; Kumar, S; Nayak, R; Xu, J; Szczur, K; Cancelas, J A; Filippi, M-D 2013. p190-B RhoGAP regulates the functional composition of the mesenchymal microenvironment. Leukemia, 27 11, 2209-19Taniguchi Ishikawa, E; Chang, K H; Nayak, R; Olsson, H A; Ficker, A M; Dunn, S K; Madhu, M N; Sengupta, A; Whitsett, J A; Grimes, H L; Cancelas, J A 2013. Klf5 controls bone marrow homing of stem cells and progenitors through Rab5-mediated β1/β2-integrin trafficking. Nature communications, 4 , 1660Dhiman, Rohan; Bandaru, Anuradha; Barnes, Peter F; Saha, Sudipto; Tvinnereim, Amy; Nayak, Ramesh C; Paidipally, Padmaja; Valluri, Vijaya Lakshmi; Rao, L Vijaya Mohan; Vankayalapati, Ramakrishna 2011. c-Maf-dependent growth of Mycobacterium tuberculosis in a CD14(hi) subpopulation of monocyte-derived macrophages. Journal of immunology (Baltimore, Md. : 1950), 186 3, 1638-45Sen, Prosenjit; Nayak, Ramesh; Clark, Curtis A; Gopalakrishnan, Ramakrishnan; Esmon, Charles T; Pendurthi, Usha R; Rao, L Vijaya Mohan 2011. Factor X binding to endothelial cell protein C receptor: comparison with factor VIIa and activated protein C. Blood, 118 9, 2635-6Gopalakrishnan, R; Hedner, U; Ghosh, S; Nayak, R C; Allen, T C; Pendurthi, U R; Rao, L V M 2010. Bio-distribution of pharmacologically administered recombinant factor VIIa (rFVIIa). Journal of thrombosis and haemostasis : JTH, 8 2, 301-10Kothari, Hema; Nayak, Ramesh C; Rao, L Vijaya Mohan; Pendurthi, Usha R 2010. Cystine 186-cystine 209 disulfide bond is not essential for the procoagulant activity of tissue factor or for its de-encryption. Blood, 115 21, 4273-83Dhiman, Rohan; Indramohan, Mohanalaxmi; Barnes, Peter F; Nayak, Ramesh C; Paidipally, Padmaja; Rao, L Vijaya Mohan; Vankayalapati, Ramakrishna 2009. IL-22 produced by human NK cells inhibits growth of Mycobacterium tuberculosis by enhancing phagolysosomal fusion. Journal of immunology (Baltimore, Md. : 1950), 183 10, 6639-45Nayak, Ramesh C; Sen, Prosenjit; Ghosh, Samit; Gopalakrishnan, Ramakrishnan; Esmon, Charles T; Pendurthi, Usha R; Rao, L Vijaya Mohan 2009. Endothelial cell protein C receptor cellular localization and trafficking: potential functional implications. Blood, 114 9, 1974-86Sahasrabuddhe, Amogh A; Nayak, Ramesh C; Gupta, Chhitar M 2009. Ancient Leishmania coronin (CRN12) is involved in microtubule remodeling during cytokinesis. Journal of cell science, 122 Pt 10, 1691-9Nayak, Ramesh C; Sahasrabuddhe, Amogh A; Bajpai, Virendra K; Gupta, Chhitar M 2005. A novel homologue of coronin colocalizes with actin in filament-like structures in Leishmania. Molecular and biochemical parasitology, 143 2, 152-64
Peer Reviewed Publications Menéndez-Gutiérrez, María Piedad; Porcuna, Jesús; Nayak, Ramesh; Paredes, Ana; Niu, Haixia; Núñez, Vanessa; Paranjpe, Aditi; Gómez, Manuel J; Bhattacharjee, Anukana; Schnell, Daniel J; Sánchez-Cabo, Fátima; Welch, John S; Salomonis, Nathan; Cancelas, Jose A; Ricote, Mercedes 2023. Retinoid X receptor promotes hematopoietic stem cell fitness and quiescence and preserves hematopoietic homeostasis. Blood, 141 6, 592-608Nayak, R C; Chang, K H; Singh, A K; Kotliar, M; Desai, M; Wellendorf, A M; Wunderlich, M; Bartram, J; Mizukawa, B; Cuadrado, M; Dexheimer, P; Barski, A; Bustelo, X R; Nassar, N N; Cancelas, J A 2022. Nuclear Vav3 is required for polycomb repression complex-1 activity in B-cell lymphoblastic leukemogenesis. Nature communications, 13 1, 3056Althoff, Mark J; Nayak, Ramesh C; Hegde, Shailaja; Wellendorf, Ashley M; Bohan, Breanna; Filippi, Marie-Dominique; Xin, Mei; Lu, Q Richard; Geiger, Hartmut; Zheng, Yi; Diaz-Meco, Maria T; Moscat, Jorge; Cancelas, Jose A 2020. Yap1-Scribble polarization is required for hematopoietic stem cell division and fate. Blood, 136 16, 1824-1836Govindarajah, Vinothini; Lee, Jung-Mi; Solomon, Michael; Goddard, Bryan; Nayak, Ramesh; Nattamai, Kalpana; Geiger, Hartmut; Salomonis, Nathan; Cancelas, Jose A; Reynaud, Damien 2020. FOXO activity adaptation safeguards the hematopoietic stem cell compartment in hyperglycemia. Blood advances, 4 21, 5512-5526Nayak, R C; Hegde, S; Althoff, M J; Wellendorf, A M; Mohmoud, F; Perentesis, J; Reina-Campos, M; Reynaud, D; Zheng, Y; Diaz-Meco, M T; Moscat, J; Cancelas, J A 2019. The signaling axis atypical protein kinase C λ/ι-Satb2 mediates leukemic transformation of B-cell progenitors. Nature communications, 10 1, 46Nayak, Ramesh C; Cancelas, Jose A 2019. Ubiquitination is not omnipresent in myeloid leukemia. Haematologica, 104 9, 1694-1696Trump, Lisa R; Nayak, Ramesh C; Singh, Abhishek K; Emberesh, Sana; Wellendorf, Ashley M; Lutzko, Carolyn M; Cancelas, Jose A 2019. Neutrophils Derived from Genetically Modified Human Induced Pluripotent Stem Cells Circulate and Phagocytose Bacteria In Vivo. Stem cells translational medicine, 8 6, 557-567Liu, Shutong; de Castro, Luis F; Jin, Ping; Civini, Sara; Ren, Jiaqiang; Reems, Jo-Anna; Cancelas, Jose; Nayak, Ramesh; Shaw, Georgina; O'Brien, Timothy; McKenna, David H; Armant, Myriam; Silberstein, Leslie; Gee, Adrian P; Hei, Derek J; Hematti, Peiman; Kuznetsov, Sergei A; Robey, Pamela G; Stroncek, David F 2017. Manufacturing Differences Affect Human Bone Marrow Stromal Cell Characteristics and Function: Comparison of Production Methods and Products from Multiple Centers. Scientific reports, 7 , 46731Chang, Kyung Hee; Nayak, Ramesh C; Roy, Swarnava; Perumbeti, Ajay; Wellendorf, Ashley M; Bezold, Katie Y; Pirman, Megan; Hill, Sarah E; Starnes, Joseph; Loberg, Anastacia; Zhou, Xuan; Inagami, Tadashi; Zheng, Yi; Malik, Punam; Cancelas, Jose A 2015. Vasculopathy-associated hyperangiotensinemia mobilizes haematopoietic stem cells/progenitors through endothelial AT₂R and cytoskeletal dysregulation. Nature communications, 6 , 5914Nayak, Ramesh C; Trump, Lisa R; Aronow, Bruce J; Myers, Kasiani; Mehta, Parinda; Kalfa, Theodosia; Wellendorf, Ashley M; Valencia, C Alexander; Paddison, Patrick J; Horwitz, Marshall S; Grimes, H Leighton; Lutzko, Carolyn; Cancelas, Jose A 2015. Pathogenesis of ELANE-mutant severe neutropenia revealed by induced pluripotent stem cells. The Journal of clinical investigation, 125 8, 3103-16Chang, Kyung Hee; Sengupta, Amitava; Nayak, Ramesh C; Duran, Angeles; Lee, Sang Jun; Pratt, Ronald G; Wellendorf, Ashley M; Hill, Sarah E; Watkins, Marcus; Gonzalez-Nieto, Daniel; Aronow, Bruce J; Starczynowski, Daniel T; Civitelli, Roberto; Diaz-Meco, Maria T; Moscat, Jorge; Cancelas, Jose A 2014. p62 is required for stem cell/progenitor retention through inhibition of IKK/NF-κB/Ccl4 signaling at the bone marrow macrophage-osteoblast niche. Cell reports, 9 6, 2084-97Tidwell, Timothy; Wechsler, Jeremy; Nayak, Ramesh C; Trump, Lisa; Salipante, Stephen J; Cheng, Jerry C; Donadieu, Jean; Glaubach, Taly; Corey, Seth J; Grimes, H Leighton; Lutzko, Carolyn; Cancelas, Jose A; Horwitz, Marshall S 2014. Neutropenia-associated ELANE mutations disrupting translation initiation produce novel neutrophil elastase isoforms. Blood, 123 4, 562-9Nayak, Ramesh C; Chang, Kyung-Hee; Vaitinadin, Nataraja-Sarma; Cancelas, Jose A 2013. Rho GTPases control specific cytoskeleton-dependent functions of hematopoietic stem cells. Immunological reviews, 256 1, 255-68Nayak, Ramesh C; Keshava, Shiva; Esmon, Charles T; Pendurthi, Usha R; Rao, L Vijaya Mohan 2013. Rab GTPases regulate endothelial cell protein C receptor-mediated endocytosis and trafficking of factor VIIa. PloS one, 8 3, e59304Raman, R; Kumar, R S; Hinge, A; Kumar, S; Nayak, R; Xu, J; Szczur, K; Cancelas, J A; Filippi, M-D 2013. p190-B RhoGAP regulates the functional composition of the mesenchymal microenvironment. Leukemia, 27 11, 2209-19Taniguchi Ishikawa, E; Chang, K H; Nayak, R; Olsson, H A; Ficker, A M; Dunn, S K; Madhu, M N; Sengupta, A; Whitsett, J A; Grimes, H L; Cancelas, J A 2013. Klf5 controls bone marrow homing of stem cells and progenitors through Rab5-mediated β1/β2-integrin trafficking. Nature communications, 4 , 1660Dhiman, Rohan; Bandaru, Anuradha; Barnes, Peter F; Saha, Sudipto; Tvinnereim, Amy; Nayak, Ramesh C; Paidipally, Padmaja; Valluri, Vijaya Lakshmi; Rao, L Vijaya Mohan; Vankayalapati, Ramakrishna 2011. c-Maf-dependent growth of Mycobacterium tuberculosis in a CD14(hi) subpopulation of monocyte-derived macrophages. Journal of immunology (Baltimore, Md. : 1950), 186 3, 1638-45Sen, Prosenjit; Nayak, Ramesh; Clark, Curtis A; Gopalakrishnan, Ramakrishnan; Esmon, Charles T; Pendurthi, Usha R; Rao, L Vijaya Mohan 2011. Factor X binding to endothelial cell protein C receptor: comparison with factor VIIa and activated protein C. Blood, 118 9, 2635-6Gopalakrishnan, R; Hedner, U; Ghosh, S; Nayak, R C; Allen, T C; Pendurthi, U R; Rao, L V M 2010. Bio-distribution of pharmacologically administered recombinant factor VIIa (rFVIIa). Journal of thrombosis and haemostasis : JTH, 8 2, 301-10Kothari, Hema; Nayak, Ramesh C; Rao, L Vijaya Mohan; Pendurthi, Usha R 2010. Cystine 186-cystine 209 disulfide bond is not essential for the procoagulant activity of tissue factor or for its de-encryption. Blood, 115 21, 4273-83Dhiman, Rohan; Indramohan, Mohanalaxmi; Barnes, Peter F; Nayak, Ramesh C; Paidipally, Padmaja; Rao, L Vijaya Mohan; Vankayalapati, Ramakrishna 2009. IL-22 produced by human NK cells inhibits growth of Mycobacterium tuberculosis by enhancing phagolysosomal fusion. Journal of immunology (Baltimore, Md. : 1950), 183 10, 6639-45Nayak, Ramesh C; Sen, Prosenjit; Ghosh, Samit; Gopalakrishnan, Ramakrishnan; Esmon, Charles T; Pendurthi, Usha R; Rao, L Vijaya Mohan 2009. Endothelial cell protein C receptor cellular localization and trafficking: potential functional implications. Blood, 114 9, 1974-86Sahasrabuddhe, Amogh A; Nayak, Ramesh C; Gupta, Chhitar M 2009. Ancient Leishmania coronin (CRN12) is involved in microtubule remodeling during cytokinesis. Journal of cell science, 122 Pt 10, 1691-9Nayak, Ramesh C; Sahasrabuddhe, Amogh A; Bajpai, Virendra K; Gupta, Chhitar M 2005. A novel homologue of coronin colocalizes with actin in filament-like structures in Leishmania. Molecular and biochemical parasitology, 143 2, 152-64
Menéndez-Gutiérrez, María Piedad; Porcuna, Jesús; Nayak, Ramesh; Paredes, Ana; Niu, Haixia; Núñez, Vanessa; Paranjpe, Aditi; Gómez, Manuel J; Bhattacharjee, Anukana; Schnell, Daniel J; Sánchez-Cabo, Fátima; Welch, John S; Salomonis, Nathan; Cancelas, Jose A; Ricote, Mercedes 2023. Retinoid X receptor promotes hematopoietic stem cell fitness and quiescence and preserves hematopoietic homeostasis. Blood, 141 6, 592-608Nayak, R C; Chang, K H; Singh, A K; Kotliar, M; Desai, M; Wellendorf, A M; Wunderlich, M; Bartram, J; Mizukawa, B; Cuadrado, M; Dexheimer, P; Barski, A; Bustelo, X R; Nassar, N N; Cancelas, J A 2022. Nuclear Vav3 is required for polycomb repression complex-1 activity in B-cell lymphoblastic leukemogenesis. Nature communications, 13 1, 3056Althoff, Mark J; Nayak, Ramesh C; Hegde, Shailaja; Wellendorf, Ashley M; Bohan, Breanna; Filippi, Marie-Dominique; Xin, Mei; Lu, Q Richard; Geiger, Hartmut; Zheng, Yi; Diaz-Meco, Maria T; Moscat, Jorge; Cancelas, Jose A 2020. Yap1-Scribble polarization is required for hematopoietic stem cell division and fate. Blood, 136 16, 1824-1836Govindarajah, Vinothini; Lee, Jung-Mi; Solomon, Michael; Goddard, Bryan; Nayak, Ramesh; Nattamai, Kalpana; Geiger, Hartmut; Salomonis, Nathan; Cancelas, Jose A; Reynaud, Damien 2020. FOXO activity adaptation safeguards the hematopoietic stem cell compartment in hyperglycemia. Blood advances, 4 21, 5512-5526Nayak, R C; Hegde, S; Althoff, M J; Wellendorf, A M; Mohmoud, F; Perentesis, J; Reina-Campos, M; Reynaud, D; Zheng, Y; Diaz-Meco, M T; Moscat, J; Cancelas, J A 2019. The signaling axis atypical protein kinase C λ/ι-Satb2 mediates leukemic transformation of B-cell progenitors. Nature communications, 10 1, 46Nayak, Ramesh C; Cancelas, Jose A 2019. Ubiquitination is not omnipresent in myeloid leukemia. Haematologica, 104 9, 1694-1696Trump, Lisa R; Nayak, Ramesh C; Singh, Abhishek K; Emberesh, Sana; Wellendorf, Ashley M; Lutzko, Carolyn M; Cancelas, Jose A 2019. Neutrophils Derived from Genetically Modified Human Induced Pluripotent Stem Cells Circulate and Phagocytose Bacteria In Vivo. Stem cells translational medicine, 8 6, 557-567Liu, Shutong; de Castro, Luis F; Jin, Ping; Civini, Sara; Ren, Jiaqiang; Reems, Jo-Anna; Cancelas, Jose; Nayak, Ramesh; Shaw, Georgina; O'Brien, Timothy; McKenna, David H; Armant, Myriam; Silberstein, Leslie; Gee, Adrian P; Hei, Derek J; Hematti, Peiman; Kuznetsov, Sergei A; Robey, Pamela G; Stroncek, David F 2017. Manufacturing Differences Affect Human Bone Marrow Stromal Cell Characteristics and Function: Comparison of Production Methods and Products from Multiple Centers. Scientific reports, 7 , 46731Chang, Kyung Hee; Nayak, Ramesh C; Roy, Swarnava; Perumbeti, Ajay; Wellendorf, Ashley M; Bezold, Katie Y; Pirman, Megan; Hill, Sarah E; Starnes, Joseph; Loberg, Anastacia; Zhou, Xuan; Inagami, Tadashi; Zheng, Yi; Malik, Punam; Cancelas, Jose A 2015. Vasculopathy-associated hyperangiotensinemia mobilizes haematopoietic stem cells/progenitors through endothelial AT₂R and cytoskeletal dysregulation. Nature communications, 6 , 5914Nayak, Ramesh C; Trump, Lisa R; Aronow, Bruce J; Myers, Kasiani; Mehta, Parinda; Kalfa, Theodosia; Wellendorf, Ashley M; Valencia, C Alexander; Paddison, Patrick J; Horwitz, Marshall S; Grimes, H Leighton; Lutzko, Carolyn; Cancelas, Jose A 2015. Pathogenesis of ELANE-mutant severe neutropenia revealed by induced pluripotent stem cells. The Journal of clinical investigation, 125 8, 3103-16Chang, Kyung Hee; Sengupta, Amitava; Nayak, Ramesh C; Duran, Angeles; Lee, Sang Jun; Pratt, Ronald G; Wellendorf, Ashley M; Hill, Sarah E; Watkins, Marcus; Gonzalez-Nieto, Daniel; Aronow, Bruce J; Starczynowski, Daniel T; Civitelli, Roberto; Diaz-Meco, Maria T; Moscat, Jorge; Cancelas, Jose A 2014. p62 is required for stem cell/progenitor retention through inhibition of IKK/NF-κB/Ccl4 signaling at the bone marrow macrophage-osteoblast niche. Cell reports, 9 6, 2084-97Tidwell, Timothy; Wechsler, Jeremy; Nayak, Ramesh C; Trump, Lisa; Salipante, Stephen J; Cheng, Jerry C; Donadieu, Jean; Glaubach, Taly; Corey, Seth J; Grimes, H Leighton; Lutzko, Carolyn; Cancelas, Jose A; Horwitz, Marshall S 2014. Neutropenia-associated ELANE mutations disrupting translation initiation produce novel neutrophil elastase isoforms. Blood, 123 4, 562-9Nayak, Ramesh C; Chang, Kyung-Hee; Vaitinadin, Nataraja-Sarma; Cancelas, Jose A 2013. Rho GTPases control specific cytoskeleton-dependent functions of hematopoietic stem cells. Immunological reviews, 256 1, 255-68Nayak, Ramesh C; Keshava, Shiva; Esmon, Charles T; Pendurthi, Usha R; Rao, L Vijaya Mohan 2013. Rab GTPases regulate endothelial cell protein C receptor-mediated endocytosis and trafficking of factor VIIa. PloS one, 8 3, e59304Raman, R; Kumar, R S; Hinge, A; Kumar, S; Nayak, R; Xu, J; Szczur, K; Cancelas, J A; Filippi, M-D 2013. p190-B RhoGAP regulates the functional composition of the mesenchymal microenvironment. Leukemia, 27 11, 2209-19Taniguchi Ishikawa, E; Chang, K H; Nayak, R; Olsson, H A; Ficker, A M; Dunn, S K; Madhu, M N; Sengupta, A; Whitsett, J A; Grimes, H L; Cancelas, J A 2013. Klf5 controls bone marrow homing of stem cells and progenitors through Rab5-mediated β1/β2-integrin trafficking. Nature communications, 4 , 1660Dhiman, Rohan; Bandaru, Anuradha; Barnes, Peter F; Saha, Sudipto; Tvinnereim, Amy; Nayak, Ramesh C; Paidipally, Padmaja; Valluri, Vijaya Lakshmi; Rao, L Vijaya Mohan; Vankayalapati, Ramakrishna 2011. c-Maf-dependent growth of Mycobacterium tuberculosis in a CD14(hi) subpopulation of monocyte-derived macrophages. Journal of immunology (Baltimore, Md. : 1950), 186 3, 1638-45Sen, Prosenjit; Nayak, Ramesh; Clark, Curtis A; Gopalakrishnan, Ramakrishnan; Esmon, Charles T; Pendurthi, Usha R; Rao, L Vijaya Mohan 2011. Factor X binding to endothelial cell protein C receptor: comparison with factor VIIa and activated protein C. Blood, 118 9, 2635-6Gopalakrishnan, R; Hedner, U; Ghosh, S; Nayak, R C; Allen, T C; Pendurthi, U R; Rao, L V M 2010. Bio-distribution of pharmacologically administered recombinant factor VIIa (rFVIIa). Journal of thrombosis and haemostasis : JTH, 8 2, 301-10Kothari, Hema; Nayak, Ramesh C; Rao, L Vijaya Mohan; Pendurthi, Usha R 2010. Cystine 186-cystine 209 disulfide bond is not essential for the procoagulant activity of tissue factor or for its de-encryption. Blood, 115 21, 4273-83Dhiman, Rohan; Indramohan, Mohanalaxmi; Barnes, Peter F; Nayak, Ramesh C; Paidipally, Padmaja; Rao, L Vijaya Mohan; Vankayalapati, Ramakrishna 2009. IL-22 produced by human NK cells inhibits growth of Mycobacterium tuberculosis by enhancing phagolysosomal fusion. Journal of immunology (Baltimore, Md. : 1950), 183 10, 6639-45Nayak, Ramesh C; Sen, Prosenjit; Ghosh, Samit; Gopalakrishnan, Ramakrishnan; Esmon, Charles T; Pendurthi, Usha R; Rao, L Vijaya Mohan 2009. Endothelial cell protein C receptor cellular localization and trafficking: potential functional implications. Blood, 114 9, 1974-86Sahasrabuddhe, Amogh A; Nayak, Ramesh C; Gupta, Chhitar M 2009. Ancient Leishmania coronin (CRN12) is involved in microtubule remodeling during cytokinesis. Journal of cell science, 122 Pt 10, 1691-9Nayak, Ramesh C; Sahasrabuddhe, Amogh A; Bajpai, Virendra K; Gupta, Chhitar M 2005. A novel homologue of coronin colocalizes with actin in filament-like structures in Leishmania. Molecular and biochemical parasitology, 143 2, 152-64