Education/CredentialsFellowship : Vanderbilt University School of Medicine (Hepatic glucose metabolism )Doctoral Degree: The Ohio State University (Exercise Physiology)Master's Degree: University of South Carolina (Exercise Physiology)Bachelor's Degree: SUNY College at Brockport (Exercise Physiology) Contact Information Medical Sciences Building 7063 Office 513-558-4437 Email winnicjn@ucmail.uc.edu Research InterestsHepatic glucose production, diabetes, liver, pancreas, glucagon, hepatic glucose uptake, liver glycogen metabolism, hypoglycemia, surgical weight loss, exercise, gastric bypass, cystic fibrosis, somatostatin. Peer Reviewed Publications Coate, Katie C; Ramnanan, Christopher J; Smith, Marta; Winnick, Jason J; Kraft, Guillaume; Irimia-Dominguez, Jose; Farmer, Ben; Donahue, E Patrick; Roach, Peter J; Cherrington, Alan D; Edgerton, Dale S 2024. Integration of metabolic flux with hepatic glucagon signaling and gene expression profiles in the conscious dog. American journal of physiology. Endocrinology and metabolism, , Coate, Katie C; Ramnanan, Christopher J; Smith, Marta; Winnick, Jason J; Kraft, Guillaume; Irimia, Jose M; Farmer, Ben; Donahue, Patrick; Roach, Peter J; Cherrington, Alan D; Edgerton, Dale S 2023. Integration of metabolic flux with hepatic glucagon signaling and gene expression profiles in the conscious dog. bioRxiv : the preprint server for biology, , Warner, Shana O; Dai, Yufei; Sheanon, Nicole; Yao, Michael V; Cason, Rebecca L; Arbabi, Shahriar; Patel, Shailendra B; Lindquist, Diana; Winnick, Jason J 2023. Short-term fasting lowers glucagon levels under euglycemic and hypoglycemic conditions in healthy humans. JCI insight, 8 12, Moore, Mary Courtney; Warner, Shana O; Dai, Yufei; Sheanon, Nicole; Smith, Marta; Farmer, Ben; Cason, Rebecca L; Cherrington, Alan D; Winnick, Jason J 2021. C-peptide enhances glucagon secretion in response to hyperinsulinemia under euglycemic and hypoglycemic conditions. JCI insight, 6 12, Warner, Shana O; Wadian, Abby M; Smith, Marta; Farmer, Ben; Dai, Yufei; Sheanon, Nicole; Edgerton, Dale S; Winnick, Jason J 2021. Liver glycogen-induced enhancements in hypoglycemic counterregulation require neuroglucopenia. American journal of physiology. Endocrinology and metabolism, 320 5, E914-E924Flynn, C Robb; Albaugh, Vance L; Tamboli, Robyn A; Gregory, Justin M; Bosompem, Amma; Sidani, Reem M; Winnick, Jason J 2020. Roux-en-Y gastric bypass surgery improves hepatic glucose metabolism and reduces plasma kisspeptin levels in morbidly obese patients with type 2 diabetes. American journal of physiology. Gastrointestinal and liver physiology, 318 2, G370-G374Warner, Shana O; Yao, Michael V; Cason, Rebecca L; Winnick, Jason J 2020. Exercise-Induced Improvements to Whole Body Glucose Metabolism in Type 2 Diabetes: The Essential Role of the Liver. Frontiers in endocrinology, 11 , 567Engelhardt, Brian G; Savani, Ujjawal; Jung, Dae Kwang; Powers, Alvin C; Jagasia, Madan; Chen, Heidi; Winnick, Jason J; Tamboli, Robyn A; Crowe, James E; Abumrad, Naji N 2019. New-Onset Post-Transplant Diabetes Mellitus after Allogeneic Hematopoietic Cell Transplant Is Initiated by Insulin Resistance, Not Immunosuppressive Medications. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 25 6, 1225-1231Gregory, Justin M; Muldowney, James A; Engelhardt, Brian G; Tyree, Regina; Marks-Shulman, Pam; Silver, Heidi J; Donahue, E Patrick; Edgerton, Dale S; Winnick, Jason J 2019. Aerobic exercise training improves hepatic and muscle insulin sensitivity, but reduces splanchnic glucose uptake in obese humans with type 2 diabetes. Nutrition & diabetes, 9 1, 25Gregory, Justin M; Rivera, Noelia; Kraft, Guillaume; Winnick, Jason J; Farmer, Ben; Allen, Eric J; Donahue, E Patrick; Smith, Marta S; Edgerton, Dale S; Williams, Phillip E; Cherrington, Alan D 2017. Glucose Autoregulation is the Dominant Component of the Hormone-Independent Counterregulatory Response to Hypoglycemia in the Conscious Dog. American journal of physiology. Endocrinology and metabolism, , ajpendo.00099.2017Kraft, Guillaume; Coate, Katie C; Winnick, Jason J; Dardevet, Dominique; Donahue, E Patrick; Cherrington, Alan D; Williams, Phillip E; Moore, Mary Courtney 2017. Glucagon's effect on liver protein metabolism in vivo. American journal of physiology. Endocrinology and metabolism, , ajpendo.00045.2017Winnick, Jason J; Kraft, Guillaume; Gregory, Justin M; Edgerton, Dale S; Williams, Phillip; Hajizadeh, Ian A; Kamal, Maahum Z; Smith, Marta; Farmer, Ben; Scott, Melanie; Neal, Doss; Donahue, E Patrick; Allen, Eric; Cherrington, Alan D 2016. Hepatic glycogen can regulate hypoglycemic counterregulation via a liver-brain axis. The Journal of clinical investigation, 126 6, 2236-48Yu, Erin Nz; Winnick, Jason J; Edgerton, Dale S; Scott, Melanie F; Smith, Marta S; Farmer, Ben; Williams, Phillip E; Cherrington, Alan D; Moore, Mary Courtney 2016. Hepatic and Whole-Body Insulin Metabolism during Proestrus and Estrus in Mongrel Dogs. Comparative medicine, 66 3, 235-40Gregory, Justin M; Kraft, Guillaume; Scott, Melanie F; Neal, Doss W; Farmer, Ben; Smith, Marta S; Hastings, Jon R; Allen, Eric J; Donahue, E Patrick; Rivera, Noelia; Winnick, Jason J; Edgerton, Dale S; Nishimura, Erica; Fledelius, Christian; Brand, Christian L; Cherrington, Alan D 2015. Insulin Delivery Into the Peripheral Circulation: A Key Contributor to Hypoglycemia in Type 1 Diabetes. Diabetes, 64 10, 3439-51Edgerton, Dale S; Moore, Mary C; Winnick, Jason J; Scott, Melanie; Farmer, Ben; Naver, Helle; Jeppesen, Claus B; Madsen, Peter; Kjeldsen, Thomas B; Nishimura, Erica; Brand, Christian L; Cherrington, Alan D 2014. Changes in glucose and fat metabolism in response to the administration of a hepato-preferential insulin analog. Diabetes, 63 11, 3946-54Winnick, J J; Ramnanan, C J; Saraswathi, V; Roop, J; Scott, M; Jacobson, P; Jung, P; Basu, R; Cherrington, A D; Edgerton, D S 2013. Effects of 11?-hydroxysteroid dehydrogenase-1 inhibition on hepatic glycogenolysis and gluconeogenesis. American journal of physiology. Endocrinology and metabolism, 304 7, E747-56Winnick, Jason J; An, Zhibo; Kraft, Guillaume; Ramnanan, Christopher J; Irimia, Jose M; Smith, Marta; Lautz, Margaret; Roach, Peter J; Cherrington, Alan D 2013. Liver glycogen loading dampens glycogen synthesis seen in response to either hyperinsulinemia or intraportal glucose infusion. Diabetes, 62 1, 96-101An, Zhibo; Winnick, Jason J; Moore, Mary C; Farmer, Ben; Smith, Marta; Irimia, Jose M; Roach, Peter J; Cherrington, Alan D 2012. A cyclic guanosine monophosphate-dependent pathway can regulate net hepatic glucose uptake in vivo. Diabetes, 61 10, 2433-41Moore, Mary Courtney; Coate, Katie C; Winnick, Jason J; An, Zhibo; Cherrington, Alan D 2012. Regulation of hepatic glucose uptake and storage in vivo. Advances in nutrition (Bethesda, Md.), 3 3, 286-94Winnick, Jason J; An, Zhibo; Ramnanan, Christopher J; Smith, Marta; Irimia, Jose M; Neal, Doss W; Moore, Mary Courtney; Roach, Peter J; Cherrington, Alan D 2011. Hepatic glycogen supercompensation activates AMP-activated protein kinase, impairs insulin signaling, and reduces glycogen deposition in the liver. Diabetes, 60 2, 398-407An, Zhibo; Winnick, Jason J; Farmer, Ben; Neal, Doss; Lautz, Margaret; Irimia, Jose M; Roach, Peter J; Cherrington, Alan D 2010. A soluble guanylate cyclase-dependent mechanism is involved in the regulation of net hepatic glucose uptake by nitric oxide in vivo. Diabetes, 59 12, 2999-3007An, Zhibo; Moore, Mary C; Winnick, Jason J; Farmer, Ben; Neal, Doss W; Lautz, Margaret; Smith, Marta; Rodewald, Tiffany; Cherrington, Alan D 2009. Portal infusion of escitalopram enhances hepatic glucose disposal in conscious dogs. European journal of pharmacology, 607 1-3, 251-7Winnick, Jason J; An, Zhibo; Moore, Mary Courtney; Ramnanan, Christopher J; Farmer, Ben; Shiota, Masakazu; Cherrington, Alan D 2009. A physiological increase in the hepatic glycogen level does not affect the response of net hepatic glucose uptake to insulin. American journal of physiology. Endocrinology and metabolism, 297 2, E358-66Winnick, Jason J; Gaillard, Trudy; Schuster, Dara P 2008. Resistance training differentially affects weight loss and glucose metabolism of White and African American patients with type 2 diabetes mellitus. Ethnicity & disease, 18 2, 152-6Winnick, Jason J; Sherman, W Michael; Habash, Diane L; Stout, Michael B; Failla, Mark L; Belury, Martha A; Schuster, Dara P 2008. Short-term aerobic exercise training in obese humans with type 2 diabetes mellitus improves whole-body insulin sensitivity through gains in peripheral, not hepatic insulin sensitivity. The Journal of clinical endocrinology and metabolism, 93 3, 771-8Winnick, Jason J; Davis, J Mark; Welsh, Ralph S; Carmichael, Martin D; Murphy, E Angela; Blackmon, Jill A 2005. Carbohydrate feedings during team sport exercise preserve physical and CNS function. Medicine and science in sports and exercise, 37 2, 306-15
Research InterestsHepatic glucose production, diabetes, liver, pancreas, glucagon, hepatic glucose uptake, liver glycogen metabolism, hypoglycemia, surgical weight loss, exercise, gastric bypass, cystic fibrosis, somatostatin.
Peer Reviewed Publications Coate, Katie C; Ramnanan, Christopher J; Smith, Marta; Winnick, Jason J; Kraft, Guillaume; Irimia-Dominguez, Jose; Farmer, Ben; Donahue, E Patrick; Roach, Peter J; Cherrington, Alan D; Edgerton, Dale S 2024. Integration of metabolic flux with hepatic glucagon signaling and gene expression profiles in the conscious dog. American journal of physiology. Endocrinology and metabolism, , Coate, Katie C; Ramnanan, Christopher J; Smith, Marta; Winnick, Jason J; Kraft, Guillaume; Irimia, Jose M; Farmer, Ben; Donahue, Patrick; Roach, Peter J; Cherrington, Alan D; Edgerton, Dale S 2023. Integration of metabolic flux with hepatic glucagon signaling and gene expression profiles in the conscious dog. bioRxiv : the preprint server for biology, , Warner, Shana O; Dai, Yufei; Sheanon, Nicole; Yao, Michael V; Cason, Rebecca L; Arbabi, Shahriar; Patel, Shailendra B; Lindquist, Diana; Winnick, Jason J 2023. Short-term fasting lowers glucagon levels under euglycemic and hypoglycemic conditions in healthy humans. JCI insight, 8 12, Moore, Mary Courtney; Warner, Shana O; Dai, Yufei; Sheanon, Nicole; Smith, Marta; Farmer, Ben; Cason, Rebecca L; Cherrington, Alan D; Winnick, Jason J 2021. C-peptide enhances glucagon secretion in response to hyperinsulinemia under euglycemic and hypoglycemic conditions. JCI insight, 6 12, Warner, Shana O; Wadian, Abby M; Smith, Marta; Farmer, Ben; Dai, Yufei; Sheanon, Nicole; Edgerton, Dale S; Winnick, Jason J 2021. Liver glycogen-induced enhancements in hypoglycemic counterregulation require neuroglucopenia. American journal of physiology. Endocrinology and metabolism, 320 5, E914-E924Flynn, C Robb; Albaugh, Vance L; Tamboli, Robyn A; Gregory, Justin M; Bosompem, Amma; Sidani, Reem M; Winnick, Jason J 2020. Roux-en-Y gastric bypass surgery improves hepatic glucose metabolism and reduces plasma kisspeptin levels in morbidly obese patients with type 2 diabetes. American journal of physiology. Gastrointestinal and liver physiology, 318 2, G370-G374Warner, Shana O; Yao, Michael V; Cason, Rebecca L; Winnick, Jason J 2020. Exercise-Induced Improvements to Whole Body Glucose Metabolism in Type 2 Diabetes: The Essential Role of the Liver. Frontiers in endocrinology, 11 , 567Engelhardt, Brian G; Savani, Ujjawal; Jung, Dae Kwang; Powers, Alvin C; Jagasia, Madan; Chen, Heidi; Winnick, Jason J; Tamboli, Robyn A; Crowe, James E; Abumrad, Naji N 2019. New-Onset Post-Transplant Diabetes Mellitus after Allogeneic Hematopoietic Cell Transplant Is Initiated by Insulin Resistance, Not Immunosuppressive Medications. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 25 6, 1225-1231Gregory, Justin M; Muldowney, James A; Engelhardt, Brian G; Tyree, Regina; Marks-Shulman, Pam; Silver, Heidi J; Donahue, E Patrick; Edgerton, Dale S; Winnick, Jason J 2019. Aerobic exercise training improves hepatic and muscle insulin sensitivity, but reduces splanchnic glucose uptake in obese humans with type 2 diabetes. Nutrition & diabetes, 9 1, 25Gregory, Justin M; Rivera, Noelia; Kraft, Guillaume; Winnick, Jason J; Farmer, Ben; Allen, Eric J; Donahue, E Patrick; Smith, Marta S; Edgerton, Dale S; Williams, Phillip E; Cherrington, Alan D 2017. Glucose Autoregulation is the Dominant Component of the Hormone-Independent Counterregulatory Response to Hypoglycemia in the Conscious Dog. American journal of physiology. Endocrinology and metabolism, , ajpendo.00099.2017Kraft, Guillaume; Coate, Katie C; Winnick, Jason J; Dardevet, Dominique; Donahue, E Patrick; Cherrington, Alan D; Williams, Phillip E; Moore, Mary Courtney 2017. Glucagon's effect on liver protein metabolism in vivo. American journal of physiology. Endocrinology and metabolism, , ajpendo.00045.2017Winnick, Jason J; Kraft, Guillaume; Gregory, Justin M; Edgerton, Dale S; Williams, Phillip; Hajizadeh, Ian A; Kamal, Maahum Z; Smith, Marta; Farmer, Ben; Scott, Melanie; Neal, Doss; Donahue, E Patrick; Allen, Eric; Cherrington, Alan D 2016. Hepatic glycogen can regulate hypoglycemic counterregulation via a liver-brain axis. The Journal of clinical investigation, 126 6, 2236-48Yu, Erin Nz; Winnick, Jason J; Edgerton, Dale S; Scott, Melanie F; Smith, Marta S; Farmer, Ben; Williams, Phillip E; Cherrington, Alan D; Moore, Mary Courtney 2016. Hepatic and Whole-Body Insulin Metabolism during Proestrus and Estrus in Mongrel Dogs. Comparative medicine, 66 3, 235-40Gregory, Justin M; Kraft, Guillaume; Scott, Melanie F; Neal, Doss W; Farmer, Ben; Smith, Marta S; Hastings, Jon R; Allen, Eric J; Donahue, E Patrick; Rivera, Noelia; Winnick, Jason J; Edgerton, Dale S; Nishimura, Erica; Fledelius, Christian; Brand, Christian L; Cherrington, Alan D 2015. Insulin Delivery Into the Peripheral Circulation: A Key Contributor to Hypoglycemia in Type 1 Diabetes. Diabetes, 64 10, 3439-51Edgerton, Dale S; Moore, Mary C; Winnick, Jason J; Scott, Melanie; Farmer, Ben; Naver, Helle; Jeppesen, Claus B; Madsen, Peter; Kjeldsen, Thomas B; Nishimura, Erica; Brand, Christian L; Cherrington, Alan D 2014. Changes in glucose and fat metabolism in response to the administration of a hepato-preferential insulin analog. Diabetes, 63 11, 3946-54Winnick, J J; Ramnanan, C J; Saraswathi, V; Roop, J; Scott, M; Jacobson, P; Jung, P; Basu, R; Cherrington, A D; Edgerton, D S 2013. Effects of 11?-hydroxysteroid dehydrogenase-1 inhibition on hepatic glycogenolysis and gluconeogenesis. American journal of physiology. Endocrinology and metabolism, 304 7, E747-56Winnick, Jason J; An, Zhibo; Kraft, Guillaume; Ramnanan, Christopher J; Irimia, Jose M; Smith, Marta; Lautz, Margaret; Roach, Peter J; Cherrington, Alan D 2013. Liver glycogen loading dampens glycogen synthesis seen in response to either hyperinsulinemia or intraportal glucose infusion. Diabetes, 62 1, 96-101An, Zhibo; Winnick, Jason J; Moore, Mary C; Farmer, Ben; Smith, Marta; Irimia, Jose M; Roach, Peter J; Cherrington, Alan D 2012. A cyclic guanosine monophosphate-dependent pathway can regulate net hepatic glucose uptake in vivo. Diabetes, 61 10, 2433-41Moore, Mary Courtney; Coate, Katie C; Winnick, Jason J; An, Zhibo; Cherrington, Alan D 2012. Regulation of hepatic glucose uptake and storage in vivo. Advances in nutrition (Bethesda, Md.), 3 3, 286-94Winnick, Jason J; An, Zhibo; Ramnanan, Christopher J; Smith, Marta; Irimia, Jose M; Neal, Doss W; Moore, Mary Courtney; Roach, Peter J; Cherrington, Alan D 2011. Hepatic glycogen supercompensation activates AMP-activated protein kinase, impairs insulin signaling, and reduces glycogen deposition in the liver. Diabetes, 60 2, 398-407An, Zhibo; Winnick, Jason J; Farmer, Ben; Neal, Doss; Lautz, Margaret; Irimia, Jose M; Roach, Peter J; Cherrington, Alan D 2010. A soluble guanylate cyclase-dependent mechanism is involved in the regulation of net hepatic glucose uptake by nitric oxide in vivo. Diabetes, 59 12, 2999-3007An, Zhibo; Moore, Mary C; Winnick, Jason J; Farmer, Ben; Neal, Doss W; Lautz, Margaret; Smith, Marta; Rodewald, Tiffany; Cherrington, Alan D 2009. Portal infusion of escitalopram enhances hepatic glucose disposal in conscious dogs. European journal of pharmacology, 607 1-3, 251-7Winnick, Jason J; An, Zhibo; Moore, Mary Courtney; Ramnanan, Christopher J; Farmer, Ben; Shiota, Masakazu; Cherrington, Alan D 2009. A physiological increase in the hepatic glycogen level does not affect the response of net hepatic glucose uptake to insulin. American journal of physiology. Endocrinology and metabolism, 297 2, E358-66Winnick, Jason J; Gaillard, Trudy; Schuster, Dara P 2008. Resistance training differentially affects weight loss and glucose metabolism of White and African American patients with type 2 diabetes mellitus. Ethnicity & disease, 18 2, 152-6Winnick, Jason J; Sherman, W Michael; Habash, Diane L; Stout, Michael B; Failla, Mark L; Belury, Martha A; Schuster, Dara P 2008. Short-term aerobic exercise training in obese humans with type 2 diabetes mellitus improves whole-body insulin sensitivity through gains in peripheral, not hepatic insulin sensitivity. The Journal of clinical endocrinology and metabolism, 93 3, 771-8Winnick, Jason J; Davis, J Mark; Welsh, Ralph S; Carmichael, Martin D; Murphy, E Angela; Blackmon, Jill A 2005. Carbohydrate feedings during team sport exercise preserve physical and CNS function. Medicine and science in sports and exercise, 37 2, 306-15
Coate, Katie C; Ramnanan, Christopher J; Smith, Marta; Winnick, Jason J; Kraft, Guillaume; Irimia-Dominguez, Jose; Farmer, Ben; Donahue, E Patrick; Roach, Peter J; Cherrington, Alan D; Edgerton, Dale S 2024. Integration of metabolic flux with hepatic glucagon signaling and gene expression profiles in the conscious dog. American journal of physiology. Endocrinology and metabolism, , Coate, Katie C; Ramnanan, Christopher J; Smith, Marta; Winnick, Jason J; Kraft, Guillaume; Irimia, Jose M; Farmer, Ben; Donahue, Patrick; Roach, Peter J; Cherrington, Alan D; Edgerton, Dale S 2023. Integration of metabolic flux with hepatic glucagon signaling and gene expression profiles in the conscious dog. bioRxiv : the preprint server for biology, , Warner, Shana O; Dai, Yufei; Sheanon, Nicole; Yao, Michael V; Cason, Rebecca L; Arbabi, Shahriar; Patel, Shailendra B; Lindquist, Diana; Winnick, Jason J 2023. Short-term fasting lowers glucagon levels under euglycemic and hypoglycemic conditions in healthy humans. JCI insight, 8 12, Moore, Mary Courtney; Warner, Shana O; Dai, Yufei; Sheanon, Nicole; Smith, Marta; Farmer, Ben; Cason, Rebecca L; Cherrington, Alan D; Winnick, Jason J 2021. C-peptide enhances glucagon secretion in response to hyperinsulinemia under euglycemic and hypoglycemic conditions. JCI insight, 6 12, Warner, Shana O; Wadian, Abby M; Smith, Marta; Farmer, Ben; Dai, Yufei; Sheanon, Nicole; Edgerton, Dale S; Winnick, Jason J 2021. Liver glycogen-induced enhancements in hypoglycemic counterregulation require neuroglucopenia. American journal of physiology. Endocrinology and metabolism, 320 5, E914-E924Flynn, C Robb; Albaugh, Vance L; Tamboli, Robyn A; Gregory, Justin M; Bosompem, Amma; Sidani, Reem M; Winnick, Jason J 2020. Roux-en-Y gastric bypass surgery improves hepatic glucose metabolism and reduces plasma kisspeptin levels in morbidly obese patients with type 2 diabetes. American journal of physiology. Gastrointestinal and liver physiology, 318 2, G370-G374Warner, Shana O; Yao, Michael V; Cason, Rebecca L; Winnick, Jason J 2020. Exercise-Induced Improvements to Whole Body Glucose Metabolism in Type 2 Diabetes: The Essential Role of the Liver. Frontiers in endocrinology, 11 , 567Engelhardt, Brian G; Savani, Ujjawal; Jung, Dae Kwang; Powers, Alvin C; Jagasia, Madan; Chen, Heidi; Winnick, Jason J; Tamboli, Robyn A; Crowe, James E; Abumrad, Naji N 2019. New-Onset Post-Transplant Diabetes Mellitus after Allogeneic Hematopoietic Cell Transplant Is Initiated by Insulin Resistance, Not Immunosuppressive Medications. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 25 6, 1225-1231Gregory, Justin M; Muldowney, James A; Engelhardt, Brian G; Tyree, Regina; Marks-Shulman, Pam; Silver, Heidi J; Donahue, E Patrick; Edgerton, Dale S; Winnick, Jason J 2019. Aerobic exercise training improves hepatic and muscle insulin sensitivity, but reduces splanchnic glucose uptake in obese humans with type 2 diabetes. Nutrition & diabetes, 9 1, 25Gregory, Justin M; Rivera, Noelia; Kraft, Guillaume; Winnick, Jason J; Farmer, Ben; Allen, Eric J; Donahue, E Patrick; Smith, Marta S; Edgerton, Dale S; Williams, Phillip E; Cherrington, Alan D 2017. Glucose Autoregulation is the Dominant Component of the Hormone-Independent Counterregulatory Response to Hypoglycemia in the Conscious Dog. American journal of physiology. Endocrinology and metabolism, , ajpendo.00099.2017Kraft, Guillaume; Coate, Katie C; Winnick, Jason J; Dardevet, Dominique; Donahue, E Patrick; Cherrington, Alan D; Williams, Phillip E; Moore, Mary Courtney 2017. Glucagon's effect on liver protein metabolism in vivo. American journal of physiology. Endocrinology and metabolism, , ajpendo.00045.2017Winnick, Jason J; Kraft, Guillaume; Gregory, Justin M; Edgerton, Dale S; Williams, Phillip; Hajizadeh, Ian A; Kamal, Maahum Z; Smith, Marta; Farmer, Ben; Scott, Melanie; Neal, Doss; Donahue, E Patrick; Allen, Eric; Cherrington, Alan D 2016. Hepatic glycogen can regulate hypoglycemic counterregulation via a liver-brain axis. The Journal of clinical investigation, 126 6, 2236-48Yu, Erin Nz; Winnick, Jason J; Edgerton, Dale S; Scott, Melanie F; Smith, Marta S; Farmer, Ben; Williams, Phillip E; Cherrington, Alan D; Moore, Mary Courtney 2016. Hepatic and Whole-Body Insulin Metabolism during Proestrus and Estrus in Mongrel Dogs. Comparative medicine, 66 3, 235-40Gregory, Justin M; Kraft, Guillaume; Scott, Melanie F; Neal, Doss W; Farmer, Ben; Smith, Marta S; Hastings, Jon R; Allen, Eric J; Donahue, E Patrick; Rivera, Noelia; Winnick, Jason J; Edgerton, Dale S; Nishimura, Erica; Fledelius, Christian; Brand, Christian L; Cherrington, Alan D 2015. Insulin Delivery Into the Peripheral Circulation: A Key Contributor to Hypoglycemia in Type 1 Diabetes. Diabetes, 64 10, 3439-51Edgerton, Dale S; Moore, Mary C; Winnick, Jason J; Scott, Melanie; Farmer, Ben; Naver, Helle; Jeppesen, Claus B; Madsen, Peter; Kjeldsen, Thomas B; Nishimura, Erica; Brand, Christian L; Cherrington, Alan D 2014. Changes in glucose and fat metabolism in response to the administration of a hepato-preferential insulin analog. Diabetes, 63 11, 3946-54Winnick, J J; Ramnanan, C J; Saraswathi, V; Roop, J; Scott, M; Jacobson, P; Jung, P; Basu, R; Cherrington, A D; Edgerton, D S 2013. Effects of 11?-hydroxysteroid dehydrogenase-1 inhibition on hepatic glycogenolysis and gluconeogenesis. American journal of physiology. Endocrinology and metabolism, 304 7, E747-56Winnick, Jason J; An, Zhibo; Kraft, Guillaume; Ramnanan, Christopher J; Irimia, Jose M; Smith, Marta; Lautz, Margaret; Roach, Peter J; Cherrington, Alan D 2013. Liver glycogen loading dampens glycogen synthesis seen in response to either hyperinsulinemia or intraportal glucose infusion. Diabetes, 62 1, 96-101An, Zhibo; Winnick, Jason J; Moore, Mary C; Farmer, Ben; Smith, Marta; Irimia, Jose M; Roach, Peter J; Cherrington, Alan D 2012. A cyclic guanosine monophosphate-dependent pathway can regulate net hepatic glucose uptake in vivo. Diabetes, 61 10, 2433-41Moore, Mary Courtney; Coate, Katie C; Winnick, Jason J; An, Zhibo; Cherrington, Alan D 2012. Regulation of hepatic glucose uptake and storage in vivo. Advances in nutrition (Bethesda, Md.), 3 3, 286-94Winnick, Jason J; An, Zhibo; Ramnanan, Christopher J; Smith, Marta; Irimia, Jose M; Neal, Doss W; Moore, Mary Courtney; Roach, Peter J; Cherrington, Alan D 2011. Hepatic glycogen supercompensation activates AMP-activated protein kinase, impairs insulin signaling, and reduces glycogen deposition in the liver. Diabetes, 60 2, 398-407An, Zhibo; Winnick, Jason J; Farmer, Ben; Neal, Doss; Lautz, Margaret; Irimia, Jose M; Roach, Peter J; Cherrington, Alan D 2010. A soluble guanylate cyclase-dependent mechanism is involved in the regulation of net hepatic glucose uptake by nitric oxide in vivo. Diabetes, 59 12, 2999-3007An, Zhibo; Moore, Mary C; Winnick, Jason J; Farmer, Ben; Neal, Doss W; Lautz, Margaret; Smith, Marta; Rodewald, Tiffany; Cherrington, Alan D 2009. Portal infusion of escitalopram enhances hepatic glucose disposal in conscious dogs. European journal of pharmacology, 607 1-3, 251-7Winnick, Jason J; An, Zhibo; Moore, Mary Courtney; Ramnanan, Christopher J; Farmer, Ben; Shiota, Masakazu; Cherrington, Alan D 2009. A physiological increase in the hepatic glycogen level does not affect the response of net hepatic glucose uptake to insulin. American journal of physiology. Endocrinology and metabolism, 297 2, E358-66Winnick, Jason J; Gaillard, Trudy; Schuster, Dara P 2008. Resistance training differentially affects weight loss and glucose metabolism of White and African American patients with type 2 diabetes mellitus. Ethnicity & disease, 18 2, 152-6Winnick, Jason J; Sherman, W Michael; Habash, Diane L; Stout, Michael B; Failla, Mark L; Belury, Martha A; Schuster, Dara P 2008. Short-term aerobic exercise training in obese humans with type 2 diabetes mellitus improves whole-body insulin sensitivity through gains in peripheral, not hepatic insulin sensitivity. The Journal of clinical endocrinology and metabolism, 93 3, 771-8Winnick, Jason J; Davis, J Mark; Welsh, Ralph S; Carmichael, Martin D; Murphy, E Angela; Blackmon, Jill A 2005. Carbohydrate feedings during team sport exercise preserve physical and CNS function. Medicine and science in sports and exercise, 37 2, 306-15