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Cristiano Spadaccio, MD

Associate Professor of Clinical

Surgery | College of Medicine

Education/Credentials
  • Focused Clinical Fellowship: Harvard Medical School - Massachusetts General Hospital
  • Residency: University Campus Bio-Medico of Rome
  • Ph.D.: La Sapienza of Rome (Biochemical Science)
  • Postdoctoral Research Fellowship: University of Pittsburgh Medical Center
  • M.D.: University Campus Bio-Medico
Languages

Italian

Contact Information

Clinical Interests

Cardiovascular Disease

Heart Failure

Aortic Aneurysm

Aortic Diseases and Disorders

Arteriosclerotic Aortic Disease

Cardiomyopathy

Thoracic Surgery

Coronary artery disease

Valvular disease

Peer Reviewed Publications

Biancari, Fausto; Mäkikallio, Timo; Loforte, Antonio; Kaserer, Alexander; Ruggieri, Vito G; Cho, Sung-Min; Kang, Jin Kook; Dalén, Magnus; Welp, Henryk; Jónsson, Kristján; Ragnarsson, Sigurdur; Hernández Pérez, Francisco J; Gatti, Giuseppe; Alkhamees, Khalid; Fiore, Antonio; Lechiancole, Andrea; Rosato, Stefano; Spadaccio, Cristiano; Pettinari, Matteo; Perrotti, Andrea; Sahli, Sebastian D; L'Acqua, Camilla; Arafat, Amr A; Albabtain, Monirah A; AlBarak, Mohammed M; Laimoud, Mohamed; Djordjevic, Ilija; Krasivskyi, Ihor; Samalavicius, Robertas; Jankuviene, Agne; Alonso-Fernandez-Gatta, Marta; Wilhelm, Markus J; Juvonen, Tatu; Mariscalco, Giovanni 2024. Inter-institutional analysis of the outcome after postcardiotomy veno-arterial extracorporeal membrane oxygenation. The International journal of artificial organs, 47 1, 25-34

Gambardella, Ivancarmine; Spadaccio, Cristiano; Singh, Sanjeet S A; Shingu, Yasushige; Kunihara, Takashi; Wakasa, Satoru; Nappi, Francesco 2024. Interpapillary muscle distance independently predicts recurrent mitral regurgitation. Journal of cardiothoracic surgery, 19 1, 147

Spadaccio, Cristiano; Nenna, Antonio; Henkens, Arnaud; Mastrobuoni, Stefano; Jahanyar, Jama; Aphram, Gaby; Lemaire, Guillaume; Vancraeynest, David; El Khoury, Gébrine; De Kerchove, Laurent 2024. Predictors of long-term stenosis in bicuspid aortic valve repair. The Journal of thoracic and cardiovascular surgery, 167 2, 611-621.e6

Spadaccio, Cristiano; Rose, David; Candura, Dario; Lopez Marco, Ana; Cerillo, Alfredo; Stefano, Pierluigi; Nasso, Giuseppe; Ramoni, Enrico; Fattouch, Khalil; Minacapelli, Alberto; Oo, Aung Y; Speziale, Giuseppe; Shelton, Kenneth; Berra, Lorenzo; Bose, Amal; Moscarelli, Marco 2024. Effect of Hospital-associated SARS-CoV-2 Infections in Cardiac Surgery: A Multicenter Study. The Annals of thoracic surgery, 117 1, 213-219

Spadaccio, Cristiano; Salsano, Antonio; Pisani, Angelo; Nenna, Antonio; Nappi, Francesco; Osho, Asishana; D'Alessandro, David; Sundt, Thoralf M; Crestanello, Juan; Engelman, Daniel; Rose, David 2024. Enhanced recovery protocols after surgery: A systematic review and meta-analysis of randomized trials in cardiac surgery. World journal of surgery, 48 4, 779-790

Biancari, Fausto; Kaserer, Alexander; Perrotti, Andrea; Ruggieri, Vito G; Cho, Sung-Min; Kang, Jin Kook; Dalén, Magnus; Welp, Henryk; Jónsson, Kristján; Ragnarsson, Sigurdur; Hernández Pérez, Francisco J; Gatti, Giuseppe; Alkhamees, Khalid; Loforte, Antonio; Lechiancole, Andrea; Rosato, Stefano; Spadaccio, Cristiano; Pettinari, Matteo; Mariscalco, Giovanni; Mäkikallio, Timo; Sahli, Sebastian D; L'Acqua, Camilla; Arafat, Amr A; Albabtain, Monirah A; AlBarak, Mohammed M; Laimoud, Mohamed; Djordjevic, Ilija; Krasivskyi, Ihor; Samalavicius, Robertas; Puodziukaite, Lina; Alonso-Fernandez-Gatta, Marta; Spahn, Donat R; Fiore, Antonio 2023. Hyperlactatemia and poor outcome After postcardiotomy veno-arterial extracorporeal membrane oxygenation: An individual patient data meta-Analysis. Perfusion, , 2676591231170978

Choi, Kukbin; Spadaccio, Cristiano; Altarabsheh, Salah E; Knop, Gustavo; Spencer, Philip J; Saddoughi, Sahar A; Tabar, Kiumars R; Hassler, Kenneth R; Villavicencio, Mauricio A 2023. Bilateral lung transplantation from a left ventricular assist device supported donor. JTCVS techniques, 19 , 164-165

Choi, Kukbin; Spadaccio, Cristiano; Ribeiro, Rafaela V P; Langlais, Blake T; Villavicencio, Mauricio A; Pennington, Kelly; Spencer, Philip J; Daly, Richard C; Mallea, Jorge; Keshavjee, Shaf; Cypel, Marcelo; Saddoughi, Sahar A 2023. Early national trends of lung allograft use during donation after circulatory death heart procurement in the United States. JTCVS open, 16 , 1020-1028

Dimagli, Arnaldo; Spadaccio, Cristiano; Myers, Annie; Demetres, Michelle; Rademaker-Havinga, Tessa; Stone, Gregg W; Spertus, John A; Redfors, Bjorn; Fremes, Stephen; Gaudino, Mario; Masterson Creber, Ruth 2023. Quality of Life After Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting. Journal of the American Heart Association, 12 22, e030069

Gaudino, Mario F L; Spadaccio, Cristiano 2023. Commentary: Methods in observational studies in valve surgery, when time matters. The Journal of thoracic and cardiovascular surgery, 165 2, 632-633

Gaudino, Mario; Di Franco, Antonino; Spadaccio, Cristiano; Rahouma, Mohamed; Robinson, N Bryce; Demetres, Michelle; Fremes, Stephen; Doenst, Torsten 2023. Difference in spontaneous myocardial infarction and mortality in percutaneous versus surgical revascularization trials: A systematic review and meta-analysis. The Journal of thoracic and cardiovascular surgery, 165 2, 662-669.e14

Hu, Hai-Ou; Zhang, Chen-Han; Spadaccio, Cristiano; Tang, Bing; Li, Cheng-Nan; Qiao, Zhi-Yu; Zheng, Tie; Zhu, Jun-Ming; Sun, Li-Zhong 2023. Surgical management of aortic regurgitation secondary to Behcet's disease. Frontiers in cardiovascular medicine, 10 , 1093024

Moon, Robert J; Spadaccio, Cristiano; Duncan, Andrew J; Bittar, Mohamad N 2023. Repair of a Late Presentation Thoracic Aortic Aneurysm following Coarctation Repair. Aorta (Stamford, Conn.), 11 1, 44-46

Nappi, Francesco; Alzamil, Almothana; Avtaar Singh, Sanjeet Singh; Spadaccio, Cristiano; Bonnet, Nicolas 2023. Current Knowledge on the Interaction of Human Cytomegalovirus Infection, Encoded miRNAs, and Acute Aortic Syndrome. Viruses, 15 10,

Nappi, Francesco; Gambardella, Ivancarmine; Singh, Sanjeet Singh Avtaar; Salsano, Antonio; Santini, Francesco; Spadaccio, Cristiano; Biancari, Fausto; Dominguez, Joaquin; Fiore, Antonio 2023. Survival following acute type A aortic dissection: a multicenter study. Journal of thoracic disease, 15 12, 6604-6622

Nappi, Francesco; Nenna, Antonio; Spadaccio, Cristiano; Avtaar Singh, Sanjeet Singh; Almazil, Almothana; Acar, Christophe 2023. The Use of the Cryopreserved Aortic Homograft for Aortic Valve Replacement: Is It Still an Option? Journal of cardiovascular development and disease, 10 6,

Nappi, Francesco; Schoell, Thibaut; Spadaccio, Cristiano; Acar, Christophe; da Costa, Francisco Diniz Affonso 2023. A Literature Review on the Use of Aortic Allografts in Modern Cardiac Surgery for the Treatment of Infective Endocarditis: Is There Clear Evidence or Is It Merely a Perception? Life (Basel, Switzerland), 13 10,

Salsano, Antonio; Nenna, Antonio; Molinari, Nicolas; Avtaar Singh, Sanjeet Singh; Spadaccio, Cristiano; Santini, Francesco; Chello, Massimo; Fiore, Antonio; Nappi, Francesco 2023. Impact of Mitral Regurgitation Recurrence on Mitral Valve Repair for Secondary Ischemic Mitral Regurgitation. Journal of cardiovascular development and disease, 10 3,

Spadaccio, Cristiano; Rose, David; Nenna, Antonio; Taylor, Rebecca; Bittar, Mohamad Nidal 2023. Early Re-Exploration versus Conservative Management for Postoperative Bleeding in Stable Patients after Coronary Artery Bypass Grafting: A Propensity Matched Study. Journal of clinical medicine, 12 9,

Audisio, Katia; Robinson, N Bryce; Soletti, Giovanni J; Cancelli, Gianmarco; Dimagli, Arnaldo; Spadaccio, Cristiano; Olaria, Roberto Perezgrovas; Chadow, David; Rahouma, Mohamed; Demetres, Michelle; Tam, Derrick Y; Benedetto, Umberto; Girardi, Leonard N; Kurlansky, Paul; Fremes, Stephen E; Gaudino, Mario 2022. A survey of retractions in the cardiovascular literature. International journal of cardiology, 349 , 109-114

Biancari, Fausto; Kaserer, Alexander; Perrotti, Andrea; Ruggieri, Vito G; Cho, Sung-Min; Kang, Jin Kook; Dalén, Magnus; Welp, Henryk; Jónsson, Kristján; Ragnarsson, Sigurdur; Hernández Pérez, Francisco J; Gatti, Giuseppe; Alkhamees, Khalid; Loforte, Antonio; Lechiancole, Andrea; Rosato, Stefano; Spadaccio, Cristiano; Pettinari, Matteo; Fiore, Antonio; Mäkikallio, Timo; Sahli, Sebastian D; L'Acqua, Camilla; Arafat, Amr A; Albabtain, Monirah A; AlBarak, Mohammed M; Laimoud, Mohamed; Djordjevic, Ilija; Krasivskyi, Ihor; Samalavicius, Robertas; Puodziukaite, Lina; Alonso-Fernandez-Gatta, Marta; Wilhelm, Markus J; Mariscalco, Giovanni 2022. Central versus Peripheral Postcardiotomy Veno-Arterial Extracorporeal Membrane Oxygenation: Systematic Review and Individual Patient Data Meta-Analysis. Journal of clinical medicine, 11 24,

Björnsdóttir, Björk; Biancari, Fausto; Dalén, Magnus; Dell'Aquila, Angelo M; Jónsson, Kristján; Fiore, Antonio; Mariscalco, Giovanni; El-Dean, Zein; Gatti, Giuseppe; Zipfel, Svante; Perrotti, Andrea; Bounader, Karl; Alkhamees, Khalid; Loforte, Antonio; Lechiancole, Andrea; Pol, Marek; Spadaccio, Cristiano; Pettinari, Matteo; De Keyzer, Dieter; Welp, Henryk; Speziale, Giuseppe; Lichtenberg, Artur; Ruggieri, Vito G; Yusuf, Hakeem; Ragnarsson, Sigurdur 2022. Postcardiotomy Venoarterial Extracorporeal Membrane Oxygenation With and Without Intra-Aortic Balloon Pump. Journal of cardiothoracic and vascular anesthesia, 36 8 Pt B, 2876-2883

Creber, Ruth Masterson; Dimagli, Arnaldo; Spadaccio, Cristiano; Myers, Annie; Moscarelli, Marco; Demetres, Michelle; Little, Matthew; Fremes, Stephen; Gaudino, Mario 2022. Effect of coronary artery bypass grafting on quality of life: a meta-analysis of randomized trials. European heart journal. Quality of care & clinical outcomes, 8 3, 259-268

Gaudino, Mario; Khan, Faiza M; Rahouma, Mohamed; Naik, Ajita; Hameed, Irbaz; Spadaccio, Cristiano; Robinson, N Bryce; Ruan, Yongle; Demetres, Michelle; Oakley, Christian T; Gambardella, Ivancarmine; Iannacone, Erin M; Lau, Christopher; Girardi, Leonard N 2022. Spinal cord injury after open and endovascular repair of descending thoracic and thoracoabdominal aortic aneurysms: A meta-analysis. The Journal of thoracic and cardiovascular surgery, 163 2, 552-564

Iervolino, Adelaide; Spadafora, Luigi; Spadaccio, Cristiano; Iervolino, Valentina; Biondi Zoccai, Giuseppe; Andreotti, Felicita 2022. Myocardial Cell Preservation from Potential Cardiotoxic Drugs: The Role of Nanotechnologies. Pharmaceutics, 15 1,

Klepper, Maureen; Noirhomme, Philippe; de Kerchove, Laurent; Mastrobuoni, Stefano; Spadaccio, Cristiano; Lemaire, Guillaume; El Khoury, Gébrine; Navarra, Emiliano 2022. Robotic mitral valve repair: A single center experience over a 7-year period. Journal of cardiac surgery, 37 8, 2266-2277

Nappi, Francesco; Giacinto, Omar; Lusini, Mario; Garo, Marialuisa; Caponio, Claudio; Nenna, Antonio; Nappi, Pierluigi; Rousseau, Juliette; Spadaccio, Cristiano; Chello, Massimo 2022. Patients with Bicuspid Aortopathy and Aortic Dilatation. Journal of clinical medicine, 11 20,

Nappi, Francesco; Spadaccio, Cristiano 2022. Ischemic Mitral Regurgitation Animal Models: Going From the Whole to the Part or Vice Versa? The Annals of thoracic surgery, 113 5, 1752-1753

Nenna, Antonio; Nappi, Francesco; Spadaccio, Cristiano; Greco, Salvatore Matteo; Pilato, Michele; Stilo, Francesco; Montelione, Nunzio; Catanese, Vincenzo; Lusini, Mario; Spinelli, Francesco; Chello, Massimo 2022. Hybrid coronary revascularization in multivessel coronary artery disease: a systematic review. Future cardiology, 18 3, 219-234

Nenna, Antonio; Nappi, Francesco; Spadaccio, Cristiano; Greco, Salvatore Matteo; Pilato, Michele; Stilo, Francesco; Montelione, Nunzio; Catanese, Vincenzo; Lusini, Mario; Spinelli, Francesco; Chello, Massimo 2022. Advanced measurements of coronary calcium scores: how does it affect current clinical practice? Future cardiology, 18 1, 35-41

Nusca, Annunziata; Viscusi, Michele Mattia; Piccirillo, Francesco; De Filippis, Aurelio; Nenna, Antonio; Spadaccio, Cristiano; Nappi, Francesco; Chello, Camilla; Mangiacapra, Fabio; Grigioni, Francesco; Chello, Massimo; Ussia, Gian Paolo 2022. In Stent Neo-Atherosclerosis: Pathophysiology, Clinical Implications, Prevention, and Therapeutic Approaches. Life (Basel, Switzerland), 12 3,

Spadaccio, Cristiano; Nenna, Antonio; Candura, Dario; Rose, David; Moscarelli, Marco; Al-Attar, Nawwar; Sutherland, Fraser 2022. Total arterial coronary artery bypass grafting in patients with preoperative anemia. Journal of cardiac surgery, 37 6, 1528-1536

Spadaccio, Cristiano; Nenna, Antonio; Rose, David; Piccirillo, Francesco; Nusca, Annunziata; Grigioni, Francesco; Chello, Massimo; Vlahakes, Gus J 2022. Correction to: The Role of Angiogenesis and Arteriogenesis in Myocardial Infarction and Coronary Revascularization. Journal of cardiovascular translational research, 15 6, 1477

Spadaccio, Cristiano; Nenna, Antonio; Rose, David; Piccirillo, Francesco; Nusca, Annunziata; Grigioni, Francesco; Chello, Massimo; Vlahakes, Gus J 2022. The Role of Angiogenesis and Arteriogenesis in Myocardial Infarction and Coronary Revascularization. Journal of cardiovascular translational research, 15 5, 1024-1048

Spadaccio, Cristiano; Pisani, Angelo; Salsano, Antonio; Nenna, Antonio; Fardman, Alexander; D'Alessandro, David; Santini, Francesco; Gaudino, Mario F L; Sundt, Thoralf M; Rose, David 2022. Treatment and outcomes of mechanical complications of acute myocardial infarction during the Covid-19 era: A comparison with the pre-Covid-19 period. A systematic review and meta-analysis. Open medicine (Warsaw, Poland), 17 1, 1412-1416

Biancari, Fausto; Perrotti, Andrea; Ruggieri, Vito G; Mariscalco, Giovanni; Dalén, Magnus; Dell'Aquila, Angelo M; Jónsson, Kristján; Ragnarsson, Sigurdur; Di Perna, Dario; Bounader, Karl; Gatti, Giuseppe; Juvonen, Tatu; Alkhamees, Khalid; Yusuff, Hakeem; Loforte, Antonio; Lechiancole, Andrea; Chocron, Sidney; Pol, Marek; Spadaccio, Cristiano; Pettinari, Matteo; De Keyzer, Dieter; Fiore, Antonio; Welp, Henryk 2021. Five-year survival after post-cardiotomy veno-arterial extracorporeal membrane oxygenation. European heart journal. Acute cardiovascular care, 10 6, 595-601

Couetil, Jean-Paul; Nappi, Francesco; Spadaccio, Cristiano; Fiore, Antonio 2021. Papillary muscle septalization for functional tricuspid regurgitation: Proof of concept and preliminary clinical experience. JTCVS techniques, 10 , 282-288

Hu, Haiou; Spadaccio, Cristiano; Zhu, Junming; Li, Chengnan; Qiao, Zhiyu; Liu, Yongmin; Moon, Marc R; Sun, Lizhong 2021. Management of aortobronchial fistula: Experience of 14 cases. Journal of cardiac surgery, 36 1, 156-161

Mariscalco, Giovanni; El-Dean, Zein; Yusuff, Hakeem; Fux, Thomas; Dell'Aquila, Angelo M; Jónsson, Kristján; Ragnarsson, Sigurdur; Fiore, Antonio; Dalén, Magnus; di Perna, Dario; Gatti, Giuseppe; Juvonen, Tatu; Zipfel, Svante; Perrotti, Andrea; Bounader, Karl; Alkhamees, Khalid; Loforte, Antonio; Lechiancole, Andrea; Pol, Marek; Spadaccio, Cristiano; Pettinari, Matteo; De Keyzer, Dieter; Welp, Henryk; Maselli, Daniele; Lichtenberg, Artur; Ruggieri, Vito G; Biancari, Fausto 2021. Duration of Venoarterial Extracorporeal Membrane Oxygenation and Mortality in Postcardiotomy Cardiogenic Shock. Journal of cardiothoracic and vascular anesthesia, 35 9, 2662-2668

Masterson Creber, Ruth; Spadaccio, Cristiano; Dimagli, Arnaldo; Myers, Annie; Taylor, Brittany; Fremes, Stephen 2021. Patient-Reported Outcomes in Cardiovascular Trials. The Canadian journal of cardiology, 37 9, 1340-1352

Nappi, Francesco; Mazzocchi, Laura; Spadaccio, Cristiano; Attias, David; Timofeva, Irina; Macron, Laurent; Iervolino, Adelaide; Morganti, Simone; Auricchio, Ferdinando 2021. CoreValve vs. Sapien 3 Transcatheter Aortic Valve Replacement: A Finite Element Analysis Study. Bioengineering (Basel, Switzerland), 8 5,

Nappi, Francesco; Nenna, Antonio; Mihos, Christos; Spadaccio, Cristiano; Gentile, Federico; Chello, Massimo; Matzui, Yoshiro 2021. Ischemic functional mitral regurgitation: from pathophysiological concepts to current treatment options. A systemic review for optimal strategy. General thoracic and cardiovascular surgery, 69 2, 213-229

Nappi, Francesco; Spadaccio, Cristiano 2021. The use of subvalvular repair for ischemic mitral regurgitation: Is it finally coming of age? JTCVS open, 8 , 290-291

Nappi, Francesco; Spadaccio, Cristiano; Mihos, Christos 2021. Too much of a good thing in ischemic mitral: lessons for surgeons and cardiologists. Reviews in cardiovascular medicine, 22 2, 259-261

Nenna, Antonio; Nappi, Francesco; Lusini, Mario; Satriano, Umberto Maria; Schilirò, Davide; Spadaccio, Cristiano; Chello, Massimo 2021. Effect of Statins on Platelet Activation and Function: From Molecular Pathways to Clinical Effects. BioMed research international, 2021 , 6661847

Spadaccio, Cristiano; Gaudino, Mario F L 2021. The Need for Randomized Trials in Cardiac Surgery. The Annals of thoracic surgery, 111 2, 636

Toivonen, Fanni; Biancari, Fausto; Dalén, Magnus; Dell'Aquila, Angelo M; Jónsson, Kristján; Fiore, Antonio; Mariscalco, Giovanni; El-Dean, Zein; Gatti, Giuseppe; Zipfel, Svante; Perrotti, Andrea; Bounader, Karl; Alkhamees, Khalid; Loforte, Antonio; Lechiancole, Andrea; Pol, Marek; Spadaccio, Cristiano; Pettinari, Matteo; De Keyzer, Dieter; Welp, Henryk; Lichtenberg, Artur; Saeed, Diyar; Ruggieri, Vito G; Ragnarsson, Sigurdur 2021. Neurologic Injury in Patients Treated With Extracorporeal Membrane Oxygenation for Postcardiotomy Cardiogenic Shock. Journal of cardiothoracic and vascular anesthesia, 35 9, 2669-2680

Vinciguerra, Mattia; Grigioni, Francesco; Romiti, Silvia; Benfari, Giovanni; Rose, David; Spadaccio, Cristiano; Cimino, Sara; De Bellis, Antonio; Greco, Ernesto 2021. Ischemic Mitral Regurgitation: A Multifaceted Syndrome with Evolving Therapies. Biomedicines, 9 5,

Vinciguerra, Mattia; Spadaccio, Cristiano; Tennyson, Charlene; Karuppannan, Mukesh; Bose, Amal; Greco, Ernesto; Rose, David 2021. Management of Patients With Aortocoronary Saphenous Vein Graft Aneurysms: JACC State-of-the-Art Review. Journal of the American College of Cardiology, 77 17, 2236-2253

Benedetto, Umberto; Avtaar Singh, Sanjeet Singh; Spadaccio, Cristiano; Moon, Marc R; Nappi, Francesco 2020. A narrative review of the interpretation of guidelines for the treatment of infective endocarditis. Annals of translational medicine, 8 23, 1623

Benedetto, Umberto; Spadaccio, Cristiano; Gentile, Federico; Moon, Marc R; Nappi, Francesco 2020. A narrative review of early surgery versus conventional treatment for infective endocarditis: do we have an answer? Annals of translational medicine, 8 23, 1626

Biancari, Fausto; Dalén, Magnus; Fiore, Antonio; Ruggieri, Vito G; Saeed, Diyar; Jónsson, Kristján; Gatti, Giuseppe; Zipfel, Svante; Perrotti, Andrea; Bounader, Karl; Loforte, Antonio; Lechiancole, Andrea; Pol, Marek; Spadaccio, Cristiano; Pettinari, Matteo; Ragnarsson, Sigurdur; Alkhamees, Khalid; Mariscalco, Giovanni; Welp, Henryk 2020. Multicenter study on postcardiotomy venoarterial extracorporeal membrane oxygenation. The Journal of thoracic and cardiovascular surgery, 159 5, 1844-1854.e6

Chello, Camilla; Lusini, Mario; Nenna, Antonio; Nappi, Francesco; Spadaccio, Cristiano; Satriano, Umberto Maria; Cardetta, Francesco; Mastroianni, Ciro; Chello, Massimo 2020. Deep Sternal Wound Infection (DSWI) and Mediastinitis After Cardiac Surgery: Current Approaches and Future Trends in Prevention and Management. Surgical technology international, 36 , 212-216

Dominici, Carmelo; Salsano, Antonio; Nenna, Antonio; Spadaccio, Cristiano; Barbato, Raffaele; Mariscalco, Giovanni; Santini, Francesco; Bashir, Mohamad; El-Dean, Zein; Chello, Massimo 2020. Higher preoperative left atrial volume index predicts lack of mitral regurgitation improvement after transcatheter aortic valve replacement. Journal of cardiovascular medicine (Hagerstown, Md.), 21 5, 383-390

Dominici, Carmelo; Salsano, Antonio; Nenna, Antonio; Spadaccio, Cristiano; Barbato, Raffaele; Mariscalco, Giovanni; Santini, Francesco; Biancari, Fausto; Chello, Massimo 2020. A Nomogram for Predicting Long Length of Stay in The Intensive Care Unit in Patients Undergoing CABG: Results From the Multicenter E-CABG Registry. Journal of cardiothoracic and vascular anesthesia, 34 11, 2951-2961

Dominici, Carmelo; Salsano, Antonio; Nenna, Antonio; Spadaccio, Cristiano; Mariscalco, Giovanni; Santini, Francesco; Chello, Massimo 2020. On-pump beating-heart coronary artery bypass grafting in high-risk patients: A systematic review and meta-analysis. Journal of cardiac surgery, 35 8, 1958-1978

Gaudino, Mario; Arvind, Varun; Hameed, Irbaz; Di Franco, Antonino; Spadaccio, Cristiano; Bhatt, Deepak L; Bagiella, Emilia 2020. Effects of the COVID-19 Pandemic on Active Non-COVID Clinical Trials. Journal of the American College of Cardiology, 76 13, 1605-1606

Khan, Faiza M; Naik, Ajita; Hameed, Irbaz; Robinson, N Bryce; Spadaccio, Cristiano; Rahouma, Mohamed; Yongle, Ruan; Demetres, Michelle; Chen, Hannah; Chang, Michelle; Girardi, Leonard N; Gaudino, Mario 2020. Open Repair of Descending Thoracic and Thoracoabdominal Aortic Aneurysms: A Meta-Analysis. The Annals of thoracic surgery, 110 6, 1941-1949

Mariscalco, Giovanni; Fiore, Antonio; Ragnarsson, Sigurdur; El-Dean, Zein; Jónsson, Kristján; Dalén, Magnus; Fux, Thomas; Ruggieri, Vito G; Gatti, Giuseppe; Juvonen, Tatu; Zipfel, Svante; Dell'Aquila, Angelo M; Perrotti, Andrea; Bounader, Karl; Settembre, Nicla; Loforte, Antonio; Livi, Ugolino; Pol, Marek; Spadaccio, Cristiano; Pettinari, Matteo; Reichart, Daniel; Alkhamees, Khalid; Welp, Henryk; Maselli, Daniele; Lichtenberg, Artur; Biancari, Fausto 2020. Venoarterial Extracorporeal Membrane Oxygenation After Surgical Repair of Type A Aortic Dissection. The American journal of cardiology, 125 12, 1901-1905

Mariscalco, Giovanni; Salsano, Antonio; Fiore, Antonio; Dalén, Magnus; Ruggieri, Vito G; Saeed, Diyar; Jónsson, Kristján; Gatti, Giuseppe; Zipfel, Svante; Dell'Aquila, Angelo M; Perrotti, Andrea; Loforte, Antonio; Livi, Ugolino; Pol, Marek; Spadaccio, Cristiano; Pettinari, Matteo; Ragnarsson, Sigurdur; Alkhamees, Khalid; El-Dean, Zein; Bounader, Karl; Biancari, Fausto 2020. Peripheral versus central extracorporeal membrane oxygenation for postcardiotomy shock: Multicenter registry, systematic review, and meta-analysis. The Journal of thoracic and cardiovascular surgery, 160 5, 1207-1216.e44

Nappi, Francesco; Avtaar Singh, Sanjeet Singh; Spadaccio, Cristiano; Acar, Christophe 2020. Ross operation 23 years after surgery: It should not be a "forgotten" option. Journal of cardiac surgery, 35 4, 952-956

Nappi, Francesco; Singh, Sanjeet Singh Avtaar; Nappi, Pierluigi; Spadaccio, Cristiano; Nenna, Antonio; Gentile, Federico; Chello, Massimo 2020. Heart Valve Endocarditis. Surgical technology international, 37 , 203-215

Nappi, Francesco; Singh, Sanjeet Singh Avtaar; Spadaccio, Cristiano; Acar, Christophe 2020. Revisiting the guidelines and choice the ideal substitute for aortic valve endocarditis. Annals of translational medicine, 8 15, 952

Nappi, Francesco; Spadaccio, Cristiano; Mihos, Christos 2020. Infective endocarditis in the 21st century. Annals of translational medicine, 8 23, 1620

Nappi, Francesco; Spadaccio, Cristiano; Mihos, Christos; Shaikhrezai, Kasra; Acar, Christophe; Moon, Marc R 2020. The quest for the optimal surgical management of tricuspid valve endocarditis in the current era: a narrative review. Annals of translational medicine, 8 23, 1628

Nappi, Francesco; Spadaccio, Cristiano; Moon, Marc R 2020. A management framework for left sided endocarditis: a narrative review. Annals of translational medicine, 8 23, 1627

Nenna, Antonio; Nappi, Francesco; Spadaccio, Cristiano; Barberi, Filippo; Greco, Salvatore Matteo; Lusini, Mario; Chello, Massimo 2020. Systolic Anterior Motion (SAM) Complicating Mitral Valve Repair: Current Concepts of Intraoperative and Postoperative Management. Surgical technology international, 37 , 225-232

Pollari, Francesco; Spadaccio, Cristiano; Cuomo, Michela; Chello, Massimo; Nenna, Antonio; Fischlein, Theodor; Nappi, Francesco 2020. Sharing of decision-making for infective endocarditis surgery: a narrative review of clinical and ethical implications. Annals of translational medicine, 8 23, 1624

Rahouma, Mohamed; Arisha, Mohammed J; Elmously, Adham; El-Sayed Ahmed, Magdy M; Spadaccio, Cristiano; Mehta, Kritika; Baudo, Massimo; Kamel, Mohamed; Mansor, Esraa; Ruan, Yongle; Morsi, Mahmoud; Shmushkevich, Shon; Eldessouki, Ihab; Rahouma, Mostafa; Mohamed, Abdelrahamn; Gambardella, Ivancarmine; Girardi, Leonard; Gaudino, Mario 2020. Cardiac tumors prevalence and mortality: A systematic review and meta-analysis. International journal of surgery (London, England), 76 , 178-189

Satriano, Umberto Maria; Nenna, Antonio; Spadaccio, Cristiano; Pollari, Francesco; Fischlein, Theodor; Chello, Massimo; Nappi, Francesco 2020. Guidelines on prosthetic heart valve management in infective endocarditis: a narrative review comparing American Heart Association/American College of Cardiology and European Society of Cardiology guidelines. Annals of translational medicine, 8 23, 1625

Spadaccio, Cristiano; Antoniades, Charalambos; Nenna, Antonio; Chung, Calvin; Will, Ricardo; Chello, Massimo; Gaudino, Mario F L 2020. Preventing treatment failures in coronary artery disease: what can we learn from the biology of in-stent restenosis, vein graft failure, and internal thoracic arteries? Cardiovascular research, 116 3, 505-519

Spadaccio, Cristiano; Gaudino, Mario F L 2020. Reply: Fractional Flow Reserve-Guided Coronary Artery Bypass Surgery: More Evidence Required to Say Less Is More. JACC. Cardiovascular interventions, 13 13, 1609

Spadaccio, Cristiano; Glineur, David; Barbato, Emanuele; Di Franco, Antonino; Oldroyd, Keith G; Biondi-Zoccai, Giuseppe; Crea, Filippo; Fremes, Stephen E; Angiolillo, Dominick J; Gaudino, Mario 2020. Fractional Flow Reserve-Based Coronary Artery Bypass Surgery: Current Evidence and Future Directions. JACC. Cardiovascular interventions, 13 9, 1086-1096

Spadaccio, Cristiano; Hu, Haiou; Li, Chengnan; Qiao, Zhiyu; Ge, Yipeng; Tie, Zheng; Zhu, Junming; Moon, Marc R; Danton, Mark; Sun, Lizhong; Gaudino, Mario F 2020. Thoracic aortic surgery: status and upcoming novelties. Minerva cardioangiologica, 68 5, 518-531

Spadaccio, Cristiano; Mazzocchi, Laura; Timofeva, Irina; Macron, Laurent; De Cecco, Carlo Nicola; Morganti, Simone; Auricchio, Ferdinando; Nappi, Francesco 2020. Bioengineering Case Study to Evaluate Complications of Adverse Anatomy of Aortic Root in Transcatheter Aortic Valve Replacement: Combining Biomechanical Modelling with CT imaging. Bioengineering (Basel, Switzerland), 7 4,

Biancari, Fausto; Fiore, Antonio; Jónsson, Kristján; Gatti, Giuseppe; Zipfel, Svante; Ruggieri, Vito G; Perrotti, Andrea; Bounader, Karl; Loforte, Antonio; Lechiancole, Andrea; Saeed, Diyar; Lichtenberg, Artur; Pol, Marek; Spadaccio, Cristiano; Pettinari, Matteo; Mogianos, Krister; Alkhamees, Khalid; Mariscalco, Giovanni; El Dean, Zein; Settembre, Nicla; Welp, Henryk; Dell'Aquila, Angelo M; Fux, Thomas; Juvonen, Tatu; Dalén, Magnus 2019. Prognostic Significance of Arterial Lactate Levels at Weaning from Postcardiotomy Venoarterial Extracorporeal Membrane Oxygenation. Journal of clinical medicine, 8 12,

Biancari, Fausto; Saeed, Diyar; Fiore, Antonio; Dalén, Magnus; Ruggieri, Vito G; Jónsson, Kristján; Gatti, Giuseppe; Zipfel, Svante; Dell'Aquila, Angelo M; Chocron, Sidney; Bounader, Karl; Amr, Gilles; Settembre, Nicla; Pälve, Kristiina; Loforte, Antonio; Gabrielli, Marco; Livi, Ugolino; Lechiancole, Andrea; Pol, Marek; Netuka, Ivan; Spadaccio, Cristiano; Pettinari, Matteo; De Keyzer, Dieter; Reichart, Daniel; Ragnarsson, Sigurdur; Alkhamees, Khalid; Lichtenberg, Artur; Fux, Thomas; El Dean, Zein; Fiorentino, Mariafrancesca; Mariscalco, Giovanni; Jeppsson, Anders; Welp, Henryk; Perrotti, Andrea 2019. Postcardiotomy Venoarterial Extracorporeal Membrane Oxygenation in Patients Aged 70 Years or Older. The Annals of thoracic surgery, 108 4, 1257-1264

Dominici, Carmelo; Salsano, Antonio; Nenna, Antonio; Spadaccio, Cristiano; El-Dean, Zein; Bashir, Mohamad; Mariscalco, Giovanni; Santini, Francesco; Chello, Massimo 2019. Neurological outcomes after on-pump vs off-pump CABG in patients with cerebrovascular disease. Journal of cardiac surgery, 34 10, 941-947

Gaudino, Mario F L; Spadaccio, Cristiano; Taggart, David P 2019. State-of-the-Art Coronary Artery Bypass Grafting: Patient Selection, Graft Selection, and Optimizing Outcomes. Interventional cardiology clinics, 8 2, 173-198

Gaudino, Mario; Lorusso, Roberto; Rahouma, Mohamed; Abouarab, Ahmed; Tam, Derrick Y; Spadaccio, Cristiano; Saint-Hilary, Gaëlle; Leonard, Jeremy; Iannaccone, Mario; D'Ascenzo, Fabrizio; Di Franco, Antonino; Soletti, Giovanni; Kamel, Mohamed K; Lau, Christopher; Girardi, Leonard N; Schwann, Thomas A; Benedetto, Umberto; Taggart, David P; Fremes, Stephen E 2019. Radial Artery Versus Right Internal Thoracic Artery Versus Saphenous Vein as the Second Conduit for Coronary Artery Bypass Surgery: A Network Meta-Analysis of Clinical Outcomes. Journal of the American Heart Association, 8 2, e010839

Giacinto, Omar; Satriano, Umberto; Nenna, Antonio; Spadaccio, Cristiano; Lusini, Mario; Mastroianni, Ciro; Nappi, Francesco; Chello, Massimo 2019. Inflammatory Response and Endothelial Dysfunction Following Cardiopulmonary Bypass: Pathophysiology and Pharmacological Targets. Recent patents on inflammation & allergy drug discovery, 13 2, 158-173

Nappi, Francesco; Nenna, Antonio; Larobina, Domenico; Rosario Carotenuto, Angelo; Jarraya, Mohamed; Spadaccio, Cristiano; Fraldi, Massimiliano; Chello, Massimo; Acar, Christophe; Carrel, Thierry 2019. Corrigendum to 'Simulating the ideal geometrical and biomechanical parameters of the pulmonary autograft to prevent failure in the Ross operation' [Interactive CardioVascular and Thoracic Surgery 2018;27:269-276]. Interactive cardiovascular and thoracic surgery, 28 1, 167

Nappi, Francesco; Spadaccio, Cristiano 2019. Mitral valve endocarditis-Unrealized expectations for repair of mitral valve. The Journal of thoracic and cardiovascular surgery, 158 2, e31-e32

Nappi, Francesco; Spadaccio, Cristiano 2019. Obstructive Cardiomyopathy and Tethering in Ischemic Mitral Regurgitation: Two Sides of the Coin. The Annals of thoracic surgery, 107 6, 1911-1912

Nappi, Francesco; Spadaccio, Cristiano; Chello, Massimo 2019. Aortic homografts: Should we really lose the opportunity? The Journal of thoracic and cardiovascular surgery, 157 5, e245-e246

Nenna, Antonio; Nappi, Francesco; Dougal, Jennifer; Satriano, Umberto; Chello, Camilla; Mastroianni, Ciro; Lusini, Mario; Chello, Massimo; Spadaccio, Cristiano 2019. Sternal wound closure in the current era: the need of a tailored approach. General thoracic and cardiovascular surgery, 67 11, 907-916

Nenna, Antonio; Spadaccio, Cristiano; Lusini, Mario; Nappi, Francesco; Mastroianni, Ciro; Giacinto, Omar; Pugliese, Giuseppe; Casacalenda, Adele; Barbato, Raffaele; Barberi, Filippo; Greco, Salvatore Matteo; Satriano, Umberto; Forte, Felice; Miano, Nicoletta; Colicchia, Camilla; Di Lorenzo, Domitilla; Gaudino, Mario; Chello, Massimo 2019. Preoperative atorvastatin reduces bleeding and blood transfusions in patients undergoing elective isolated aortic valve replacement. Interactive cardiovascular and thoracic surgery, 29 1, 51-58

Piccirillo, Francesco; Carpenito, Myriam; Verolino, Giuseppe; Chello, Camilla; Nusca, Annunziata; Lusini, Mario; Spadaccio, Cristiano; Nappi, Francesco; Di Sciascio, Germano; Nenna, Antonio 2019. Changes of the coronary arteries and cardiac microvasculature with aging: Implications for translational research and clinical practice. Mechanisms of ageing and development, 184 , 111161

Shaikhrezai, Kasra; Spadaccio, Cristiano; Hunter, Steven 2019. Box Lesion with Single Radiofrequency Clamp. The Thoracic and cardiovascular surgeon, 67 2, 117-119

Spadaccio, Cristiano; Alkhamees, Khalid; Al-Attar, Nawwar 2019. Recent advances in aortic valve replacement. F1000Research, 8 ,

Spadaccio, Cristiano; Fremes, Stephen E; Gaudino, Mario F L 2019. Right internal thoracic or radial artery as the second arterial conduit for coronary artery bypass surgery. Current opinion in cardiology, 34 5, 564-570

Spadaccio, Cristiano; Gaudino, Mario F L 2019. Are we doing a good job with coronary artery bypass grafting? European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 55 5, 901-902

Spadaccio, Cristiano; Rainer, Alberto; Barbato, Raffaele; Trombetta, Marcella; Chello, Massimo; Meyns, Bart 2019. The long-term follow-up of large-diameter Dacron® vascular grafts in surgical practice: a review. The Journal of cardiovascular surgery, 60 4, 501-513

Fraldi, Massimiliano; Spadaccio, Cristiano; Acar, Christophe; Nappi, Francesco 2018. Best to Clarify to Avoid Misunderstandings in the Biomechanics of Ross Operation: Parentheses Matter. The Annals of thoracic surgery, 106 2, 641-642

Nappi, Francesco; Nenna, Antonio; Larobina, Domenico; Carotenuto, Angelo Rosario; Jarraya, Mohamed; Spadaccio, Cristiano; Fraldi, Massimiliano; Chello, Massimo; Acar, Christophe; Carrel, Thierry 2018. Simulating the ideal geometrical and biomechanical parameters of the pulmonary autograft to prevent failure in the Ross operation. Interactive cardiovascular and thoracic surgery, 27 2, 269-276

Nappi, Francesco; Nenna, Antonio; Petitti, Tommasangelo; Spadaccio, Cristiano; Gambardella, Ivancarmine; Lusini, Mario; Chello, Massimo; Acar, Christophe 2018. Long-term outcome of cryopreserved allograft for aortic valve replacement. The Journal of thoracic and cardiovascular surgery, 156 4, 1357-1365.e6

Nappi, Francesco; Spadaccio, Cristiano 2018. keep fumbling around in the dark when it comes to infective endocarditis, or produce new, reliable data to redesign the guidelines? The Journal of thoracic and cardiovascular surgery, 155 1, 75-76

Nappi, Francesco; Spadaccio, Cristiano; Dreyfus, Julien; Attias, David; Acar, Christophe; Bando, Ko 2018. Mitral endocarditis: A new management framework. The Journal of thoracic and cardiovascular surgery, 156 4, 1486-1495.e4

Nappi, Francesco; Spadaccio, Cristiano; Mihos, Christos G; Fraldi, Massimiliano 2018. Euler's elastica-based biomechanical assessment for neochordal insertion in the treatment of degenerative mitral valve repair. The Journal of thoracic and cardiovascular surgery, 155 2, 603-605

Spadaccio, Cristiano; Benedetto, Umberto 2018. Coronary artery bypass grafting (CABG) vs. percutaneous coronary intervention (PCI) in the treatment of multivessel coronary disease: quo vadis? -a review of the evidences on coronary artery disease. Annals of cardiothoracic surgery, 7 4, 506-515

Spadaccio, Cristiano; Dalby, Matthew; Danton, Mark H D 2018. Daytime variations in perioperative myocardial injury. Lancet (London, England), 391 10135, 2105-2106

Spadaccio, Cristiano; Nenna, Antonio; Nappi, Francesco; Barbato, Raffaele; Greco, Salvatore Matteo; Nusca, Annunziata; Sommariva, Luigi; Chello, Massimo 2018. Single-territory incomplete surgical revascularization improves regional wall motion of remote ventricular areas: results from a propensity-matched study. Journal of geriatric cardiology : JGC, 15 7, 479-485

Fraldi, Massimiliano; Spadaccio, Cristiano; Mihos, Christos G; Nappi, Francesco 2017. Analysing the reasons of failure of surgical mitral repair approaches-do we need to better think in biomechanics? Journal of thoracic disease, 9 Suppl 7, S661-S664

Gambardella, Ivancarmine; Antoniou, George A; Torella, Francesco; Spadaccio, Cristiano; Oo, Aung Y; Gaudino, Mario; Nappi, Francesco; Shaw, Matthew A; Girardi, Leonard N 2017. Secondary Open Aortic Procedure Following Thoracic Endovascular Aortic Repair: Meta-Analytic State of the Art. Journal of the American Heart Association, 6 9,

Gambardella, Ivancarmine; Gaudino, Mario; Lau, Christopher; Munjal, Monica; Di Franco, Antonino; Ohmes, Lucas B; Hameedi, Fawad; Spadaccio, Cristiano; Girardi, Leonard N 2017. Contemporary results of hemiarch replacement. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 52 2, 333-338

Nappi, Francesco; Nenna, Antonio; Spadaccio, Cristiano; Chello, Massimo 2017. Pulmonary autograft in aortic position: is everything known? Translational pediatrics, 6 1, 11-17

Nappi, Francesco; Spadaccio, Cristiano 2017. Simplest solutions are not always the cleverest: Can we stitch in an infected annulus? Should we rethink the current guidelines? The Journal of thoracic and cardiovascular surgery, 154 6, 1899-1900

Nappi, Francesco; Spadaccio, Cristiano 2017. Biomechanics of failed ischemic mitral valve repair: Discovering new frontiers. The Journal of thoracic and cardiovascular surgery, 154 3, 832-833

Nappi, Francesco; Spadaccio, Cristiano; Acar, Christophe 2017. Use of allogeneic tissue to treat infective valvular disease: Has everything been said? The Journal of thoracic and cardiovascular surgery, 153 4, 824-828

Nappi, Francesco; Spadaccio, Cristiano; Chello, Massimo; Mihos, Christos G 2017. Papillary muscle approximation in mitral valve repair for secondary MR. Journal of thoracic disease, 9 Suppl 7, S635-S639

Nappi, Francesco; Spadaccio, Cristiano; Mihos, Christos G; Fraldi, Massimiliano 2017. Biomechanics raises solution to avoid geometric mitral valve configuration abnormalities in ischemic mitral regurgitation. Journal of thoracic disease, 9 Suppl 7, S624-S628

Nappi, Francesco; Spadaccio, Cristiano; Nenna, Antonio; Lusini, Mario; Fraldi, Massimiliano; Acar, Christophe; Chello, Massimo 2017. Is subvalvular repair worthwhile in severe ischemic mitral regurgitation? Subanalysis of the Papillary Muscle Approximation trial. The Journal of thoracic and cardiovascular surgery, 153 2, 286-295.e2

Nappi, Francesco; Spadaccio, Cristiano; Sablayrolles, Jean-Louis 2017. Delayed prosthesis malposition after transcatheter aortic valve implantation causing coronaries obstruction. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 52 6, 1227-1228

Nenna, Antonio; Lusini, Mario; Spadaccio, Cristiano; Nappi, Francesco; Greco, Salvatore Matteo; Barbato, Raffaele; Covino, Elvio; Chello, Massimo 2017. Heart rate variability: a new tool to predict complications in adult cardiac surgery. Journal of geriatric cardiology : JGC, 14 11, 662-668

Nenna, Antonio; Lusini, Mario; Spadaccio, Cristiano; Nappi, Francesco; Prestipino, Filippo; Barbato, Raffaele; Casacalenda, Adele; Pugliese, Giuseppe; Barberi, Filippo; Giacinto, Omar; Petitti, Tommasangelo; Covino, Elvio; Chello, Massimo 2017. Preoperative atorvastatin reduces bleeding and blood products use in patients undergoing on-pump coronary artery bypass grafting. Journal of cardiovascular medicine (Hagerstown, Md.), 18 12, 976-982

Piemonte, Vincenzo; Spadaccio, Cristiano; Capocelli, Mauro 2017. Challenges in the Field of Biomedical Devices: A Multidisciplinary Perspective. Artificial organs, 41 12, 1081-1084

Prestipino, Filippo; Nenna, Antonio; Spadaccio, Cristiano; Chello, Massimo 2017. Coronary surgery in the contest of new and old antiplatelet therapies: is it only a matter of suspension timing? European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 51 2, 400-401

Spadaccio, Cristiano; Elkasrawy, Karim; Sutherland, Fraser W H 2017. New minimally invasive surgical approach for excision of left atrial myxoma. General thoracic and cardiovascular surgery, 65 10, 605-608

Spadaccio, Cristiano; Nappi, Francesco; De Marco, Federico; Sedati, Pietro; Taffon, Chiara; Nenna, Antonio; Crescenzi, Anna; Chello, Massimo; Trombetta, Marcella; Gambardella, Ivancarmine; Rainer, Alberto 2017. Implantation of a Poly-L-Lactide GCSF-Functionalized Scaffold in a Model of Chronic Myocardial Infarction. Journal of cardiovascular translational research, 10 1, 47-65

Dapunt, Otto E; Luha, Olev; Ebner, Adrian; Sonecki, Piotr; Spadaccio, Cristiano; Sutherland, Fraser W H 2016. New Less Invasive Approach for Direct Aortic Transcatheter Aortic Valve Replacement Using Novel CoreVista Transcervical Access System. JACC. Cardiovascular interventions, 9 7, 750-3

Dapunt, Otto E; Luha, Olev; Ebner, Adrian; Sonecki, Piotr; Spadaccio, Cristiano; Sutherland, Fraser W H 2016. First-in-Man Transcervical Surgical Aortic Valve Replacement Using the CoreVista System. Innovations (Philadelphia, Pa.), 11 2, 84-93

Nappi, Francesco; Carotenuto, Angelo Rosario; Di Vito, Donato; Spadaccio, Cristiano; Acar, Cristophe; Fraldi, Massimiliano 2016. Stress-shielding, growth and remodeling of pulmonary artery reinforced with copolymer scaffold and transposed into aortic position. Biomechanics and modeling in mechanobiology, 15 5, 1141-57

Nappi, Francesco; Cristiano, Spadaccio; Nenna, Antonio; Chello, Massimo 2016. Ischemic mitral valve prolapse. Journal of thoracic disease, 8 12, 3752-3761

Nappi, Francesco; Fraldi, Massimiliano; Spadaccio, Cristiano; Carotenuto, Angelo Rosario; Montagnani, Stefania; Castaldo, Clotilde; Chachques, Juan Carlos; Acar, Christophe 2016. Biomechanics drive histological wall remodeling of neoaortic root: A mathematical model to study the expression levels of ki 67, metalloprotease, and apoptosis transition. Journal of biomedical materials research. Part A, 104 11, 2785-93

Nappi, Francesco; Lusini, Mario; Spadaccio, Cristiano; Nenna, Antonio; Covino, Elvio; Acar, Christophe; Chello, Massimo 2016. Papillary Muscle Approximation Versus Restrictive Annuloplasty Alone for Severe Ischemic Mitral Regurgitation. Journal of the American College of Cardiology, 67 20, 2334-2346

Nappi, Francesco; Nenna, Antonio; Spadaccio, Cristiano; Lusini, Mario; Chello, Massimo; Fraldi, Massimiliano; Acar, Christophe 2016. Predictive factors of long-term results following valve repair in ischemic mitral valve prolapse. International journal of cardiology, 204 , 218-28

Nappi, Francesco; Spadaccio, Cristiano 2016. Coronary artery bypass grafting (CABG) alone in moderate ischemic mitral regurgitation: is CABG really enough? Annals of translational medicine, 4 20, 413

Nappi, Francesco; Spadaccio, Cristiano; Chello, Massimo; Lusini, Mario; Acar, Christophe 2016. Double row of overlapping sutures for downsizing annuloplasty decreases the risk of residual regurgitation in ischaemic mitral valve repair. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 49 4, 1182-7

Nappi, Francesco; Spadaccio, Cristiano; Fraldi, Massimiliano 2016. Reply: Papillary Muscle Approximation Is an Anatomically Correct Repair for Ischemic Mitral Regurgitation. Journal of the American College of Cardiology, 68 10, 1147-8

Nappi, Francesco; Spadaccio, Cristiano; Fraldi, Massimiliano; Montagnani, Stefania; Fouret, Pierre; Chachques, Juan Carlos; Acar, Christophe 2016. A composite semiresorbable armoured scaffold stabilizes pulmonary autograft after the Ross operation: Mr Ross's dream fulfilled. The Journal of thoracic and cardiovascular surgery, 151 1, 155-64.e1

Nappi, Francesco; Spadaccio, Cristiano; Sablayrolles, Jean Louis 2016. Pushing the Limits in Transcatheter Aortic Valve Replacement: High-Volume Center's Effect, Overconfidence, or Something Else? JACC. Cardiovascular interventions, 9 21, 2186-2188

Nappi, Francesco; Sutherland, Fraser W H; Al-Attar, Nawwar; Spadaccio, Cristiano 2016. Incomplete Revascularization in PCI and CABG: When Two Plus Two Does Not Make Four. Journal of the American College of Cardiology, 68 8, 877-8

Nenna, Antonio; Nappi, Francesco; Chello, Massimo; Spadaccio, Cristiano 2016. Targeting Advanced Glycation End Products in Cardiac Surgery: The Unexplored Alternative. Research in cardiovascular medicine, 5 2, e31707

Nenna, Antonio; Spadaccio, Cristiano; Lusini, Mario; Barbato, Raffaele; Chello, Massimo; Nappi, Francesco 2016. Hybrid Coronary Revascularization: An Attractive Alternative Between Actual Results and Future Trends. Surgical technology international, 28 , 204-10

Nenna, Antonio; Spadaccio, Cristiano; Prestipino, Filippo; Lusini, Mario; Sutherland, Fraser W; Beattie, Gwyn W; Petitti, Tommasangelo; Nappi, Francesco; Chello, Massimo 2016. Effect of Preoperative Aspirin Replacement With Enoxaparin in Patients Undergoing Primary Isolated On-Pump Coronary Artery Bypass Grafting. The American journal of cardiology, 117 4, 563-570

Prestipino, Filippo; Spadaccio, Cristiano; Nenna, Antonio; Sutherland, Fraser Wh; Beattie, Gwyn W; Lusini, Mario; Nappi, Francesco; Chello, Massimo 2016. Off-pump coronary artery bypass grafting versus optimal medical therapy alone: effectiveness of incomplete revascularization in high risk patients. Journal of geriatric cardiology : JGC, 13 1, 23-30

Spadaccio, Cristiano; Coccia, Raffaella; Perluigi, Marzia; Pupo, Gilda; Schininà, Maria Eugenia; Giorgi, Alessandra; Blarzino, Carla; Nappi, Francesco; Sutherland, Fraser W; Chello, Massimo; Di Domenico, Fabio 2016. Redox proteomic analysis of serum from aortic anerurysm patients: insights on oxidation of specific protein target. Molecular bioSystems, 12 7, 2168-77

Spadaccio, Cristiano; Fraldi, Massimiliano; Sablayrolles, Jean Louis; Nappi, Francesco 2016. TAVI in Lower Risk Patients: Revolution or Nonsense? Keep Calm and Select Patients. Journal of the American College of Cardiology, 67 11, 1380-1

Spadaccio, Cristiano; Mozetic, Pamela; Nappi, Francesco; Nenna, Antonio; Sutherland, Fraser; Trombetta, Marcella; Chello, Massimo; Rainer, Alberto 2016. Cells and extracellular matrix interplay in cardiac valve disease: because age matters. Basic research in cardiology, 111 2, 16

Spadaccio, Cristiano; Nappi, Francesco; Al-Attar, Nawwar; Coccia, Raffaella; Perluigi, Marzia; Di Domenico, Fabio 2016. CURRENT DEVELOPMENTS IN DRUG ELUTING DEVICES: Introductory Editorial: Drug-Eluting Stents or Drug-Eluting Grafts? Insights from Proteomic Analysis. Drug target insights, 10 Suppl 1, 15-19

Spadaccio, Cristiano; Nappi, Francesco; Al-Attar, Nawwar; Sutherland, Fraser W; Acar, Christophe; Nenna, Antonio; Trombetta, Marcella; Chello, Massimo; Rainer, Alberto 2016. Old Myths, New Concerns: the Long-Term Effects of Ascending Aorta Replacement with Dacron Grafts. Not All That Glitters Is Gold. Journal of cardiovascular translational research, 9 4, 334-42

Spadaccio, Cristiano; Nappi, Francesco; De Marco, Federico; Sedati, Pietro; Sutherland, Fraser W H; Chello, Massimo; Trombetta, Marcella; Rainer, Alberto 2016. Preliminary In Vivo Evaluation of a Hybrid Armored Vascular Graft Combining Electrospinning and Additive Manufacturing Techniques. Drug target insights, 10 Suppl 1, 1-7

Spadaccio, Cristiano; Nappi, Francesco; Nenna, Antonio; Beattie, Gwyn; Chello, Massimo; Sutherland, Fraser W H 2016. Is it time to change how we think about incomplete coronary revascularization? International journal of cardiology, 224 , 295-298

Nappi, Francesco; Spadaccio, Cristiano; Acar, Christophe 2015. The future of Ross procedure. Annals of pediatric cardiology, 8 3, 256-7

Nappi, Francesco; Spadaccio, Cristiano; Al-Attar, Nawwar; Acar, Christophe 2015. The Ross procedure at the crossroads: lessons from biology: is Dr Ross's dream concluded? International journal of cardiology, 178 , 37-9

Nappi, Francesco; Spadaccio, Cristiano; Barbato, Raffaele; Lusini, Mario; Chello, Massimo 2015. Successful Valve Prolapse Repair for Ischemic Mitral Regurgitation: Combined Papillary Muscle Approximation and Mitral Chordae System Replacement. Surgical technology international, 26 , 192-6

Nappi, Francesco; Spadaccio, Cristiano; Chello, Massimo; Acar, Christophe 2015. The Ross procedure: Underuse or under-comprehension? The Journal of thoracic and cardiovascular surgery, 149 5, 1463-4

Nappi, Francesco; Spadaccio, Cristiano; Fouret, Pierre; Hammoudi, Nadjib; Chachques, Juan Carlos; Chello, Massimo; Acar, Christophe 2015. An experimental model of the Ross operation: Development of resorbable reinforcements for pulmonary autografts. The Journal of thoracic and cardiovascular surgery, 149 4, 1134-42

Nappi, Francesco; Spadaccio, Cristiano; Fraldi, Massimiliano; Acar, Cristophe 2015. Use of bioresorbable scaffold for neopulmonary artery in simple transposition of great arteries: Tissue engineering moves steps in pediatric cardiac surgery. International journal of cardiology, 201 , 639-43

Nenna, Antonio; Nappi, Francesco; Avtaar Singh, Sanjeet Singh; Sutherland, Fraser W; Di Domenico, Fabio; Chello, Massimo; Spadaccio, Cristiano 2015. Pharmacologic Approaches Against Advanced Glycation End Products (AGEs) in Diabetic Cardiovascular Disease. Research in cardiovascular medicine, 4 2, e26949

Nenna, Antonio; Spadaccio, Cristiano; Lusini, Mario; Ulianich, Luca; Chello, Massimo; Nappi, Francesco 2015. Basic and Clinical Research Against Advanced Glycation End Products (AGEs): New Compounds to Tackle Cardiovascular Disease and Diabetic Complications. Recent advances in cardiovascular drug discovery, 10 1, 10-33

Patti, Giuseppe; Bennett, Rachel; Seshasai, Sreenivasa Rao Kondapally; Cannon, Christopher P; Cavallari, Ilaria; Chello, Massimo; Nusca, Annunziata; Mega, Simona; Caorsi, Carlos; Spadaccio, Cristiano; Keun On, Young; Mannacio, Vito; Berkan, Ocal; Yilmaz, Mehmet B; Katrancioglu, Nurkay; Ji, Qiang; Kourliouros, Antonios; Baran, Çağdaş; Pasceri, Vincenzo; Rüçhan Akar, Ahmet; Carlos Kaski, Juan; Di Sciascio, Germano; Ray, Kausik K 2015. Statin pretreatment and risk of in-hospital atrial fibrillation among patients undergoing cardiac surgery: a collaborative meta-analysis of 11 randomized controlled trials. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 17 6, 855-63

Spadaccio, Cristiano; Montagnani, Stefania; Acar, Christophe; Nappi, Francesco 2015. Introducing bioresorbable scaffolds into the show. A potential adjunct to resuscitate Ross procedure. International journal of cardiology, 190 , 50-2

Spadaccio, Cristiano; Rainer, Alberto; Mozetic, Pamela; Trombetta, Marcella; Dion, Robert A; Barbato, Raffaele; Nappi, Francesco; Chello, Massimo 2015. The role of extracellular matrix in age-related conduction disorders: a forgotten player? Journal of geriatric cardiology : JGC, 12 1, 76-82

Nappi, Francesco; Al-Attar, Nawwar; Spadaccio, Cristiano; Chello, Massimo; Lusini, Mario; Acar, Christophe 2014. Aortic valve homograft: 10-year experience. Surgical technology international, 24 , 265-72

Nappi, Francesco; Spadaccio, Cristiano; Al-Attar, Nawwar; Chello, Massimo; Lusini, Mario; Barbato, Raffaele; Acar, Christophe 2014. Downsizing annuloplasty in ischemic mitral regurgitation: double row overlapping suture to avoid ring disinsertion in valve repair. Surgical technology international, 25 , 203-6

Nappi, Francesco; Spadaccio, Cristiano; Castaldo, Clotilde; Di Meglio, Franca; Nurzynska, Daria; Montagnani, Stefania; Chello, Massimo; Acar, Christophe 2014. Reinforcement of the pulmonary artery autograft with a polyglactin and polydioxanone mesh in the Ross operation: experimental study in growing lamb. The Journal of heart valve disease, 23 2, 145-8

Nappi, Francesco; Spadaccio, Cristiano; Chello, Massimo; Lusini, Mario; Acar, Cristophe 2014. Impact of structural valve deterioration on outcomes in the cryopreserved mitral homograft valve. Journal of cardiac surgery, 29 5, 616-22

Pragliola, Claudio; Chello, Massimo; Gaudino, Mario; Mazza, Andrea; Cellini, Carlo; Spadaccio, Cristiano; Covino, Elvio 2014. Long-term results of an open flexible prosthetic band for mitral insufficiency. Asian cardiovascular & thoracic annals, 22 7, 811-5

Prestipino, Filippo; Lusini, Mario; Spadaccio, Cristiano; Chello, Massimo 2014. Severe stenosis of left coronary artery originating from right sinus of Valsalva treated with off-pump coronary artery bypass surgery. Interactive cardiovascular and thoracic surgery, 19 2, 347-9

Smeets, Christophe J P; Bertrand, Philippe B; Spadaccio, Cristiano; Beran, Maud; Verhaert, David; Vandervoort, Pieter M; Gutermann, Herbert; Dion, Robert A 2014. Pulmonary homograft endocarditis and aortic autograft failure after Ross procedure: a double stentless bioprosthesis approach. The Journal of heart valve disease, 23 3, 360-3

Spadaccio, Cristiano; De Marco, Federico; Di Domenico, Fabio; Coccia, Raffaella; Lusini, Mario; Barbato, Raffaele; Covino, Elvio; Chello, Massimo 2014. Simvastatin attenuates the endothelial pro-thrombotic shift in saphenous vein grafts induced by Advanced glycation endproducts. Thrombosis research, 133 3, 418-25

Spadaccio, Cristiano; Gutermann, Herbert; Dion, Robert 2014. Mitral valvuloplasty: when the art of repair meets the biological science. The Journal of heart valve disease, 23 3, 299-301

Chello, Massimo; Spadaccio, Cristiano 2013. ABO gene variants and increased risk of atherosclerosis. Atherosclerosis, 228 2, 327-8

Chello, Massimo; Spadaccio, Cristiano 2013. Pleiotropic effects of long-term monotherapy with rosuvastatin in dogs with moderate heart failure. Cardiology, 124 1, 36-7

Spadaccio, Cristiano; Patti, Giuseppe; De Marco, Federico; Coccia, Raffaella; Di Domenico, Fabio; Pollari, Francesco; Zanzonico, Roberta; Pettinari, Matteo; Lusini, Mario; Di Sciascio, Germano; Covino, Elvio; Chello, Massimo 2013. Usefulness of preprocedural levels of advanced glycation end products to predict restenosis in patients with controlled diabetes mellitus undergoing drug-eluting stent implantation for stable angina pectoris (from the Prospective ARMYDA-AGEs Study). The American journal of cardiology, 112 1, 21-6

Spadaccio, Cristiano; Rainer, Alberto; Barbato, Raffaele; Chello, Massimo; Meyns, Bart 2013. The fate of large-diameter Dacron® vascular grafts in surgical practice: are we really satisfied? International journal of cardiology, 168 5, 5028-9

Spadaccio, Cristiano; Rainer, Alberto; De Marco, Federico; Lusini, Mario; Gallo, Paolo; Sedati, Pietro; Muda, Andrea Onetti; De Porcellinis, Stefano; Gregorj, Chiara; Avvisati, Giuseppe; Trombetta, Marcella; Chello, Massimo; Covino, Elvio; Bull, David A; Patel, Amit N; Genovese, Jorge A 2013. In situ electrostimulation drives a regenerative shift in the zone of infarcted myocardium. Cell transplantation, 22 3, 493-503

Spadaccio, Cristiano; Di Domenico, Fabio; Perluigi, Marzia; Lusini, Mario; Giorgi, Alessandra; Schininà, Maria Eugenia; Blarzino, Carla; Covino, Elvio; Chello, Massimo; Coccia, Raffaella 2012. Serum proteomics in patients with diagnosis of abdominal aortic aneurysm. Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology, 21 4, 283-90

Lusini, Mario; Barbato, Raffaele; Spadaccio, Cristiano; Chello, Massimo 2011. Aortic valve replacement in a patient with severe nickel allergy. Journal of cardiac surgery, 26 6, 618-20

Rainer, Alberto; Spadaccio, Cristiano; Sedati, Pietro; De Marco, Federico; Carotti, Simone; Lusini, Mario; Vadalà, Gianluca; Di Martino, Alberto; Morini, Sergio; Chello, Massimo; Covino, Elvio; Denaro, Vincenzo; Trombetta, Marcella 2011. Electrospun hydroxyapatite-functionalized PLLA scaffold: potential applications in sternal bone healing. Annals of biomedical engineering, 39 7, 1882-90

Spadaccio, Cristiano; Rainer, Alberto; Chachques, Juan C; Covino, Elvio; Herreros, Jesus; Genovese, Jorge A 2011. Stem cells cardiac differentiation in 3D systems. Frontiers in bioscience (Scholar edition), 3 3, 901-18

Spadaccio, Cristiano; Rainer, Alberto; Trombetta, Marcella; Centola, Matteo; Lusini, Mario; Chello, Massimo; Covino, Elvio; De Marco, Federico; Coccia, Raffaella; Toyoda, Yoshiya; Genovese, Jorge A 2011. A G-CSF functionalized scaffold for stem cells seeding: a differentiating device for cardiac purposes. Journal of cellular and molecular medicine, 15 5, 1096-108

Rainer, Alberto; Centola, Matteo; Spadaccio, Cristiano; De Porcellinis, Stefano; Abbruzzese, Franca; Genovese, Jorge A; Trombetta, Marcella 2010. A biomimetic three-layered compartmented scaffold for vascular tissue engineering. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2010 , 839-42

Rainer, Alberto; Centola, Matteo; Spadaccio, Cristiano; Gherardi, Giovanni; Genovese, Jorge A; Licoccia, Silvia; Trombetta, Marcella 2010. Comparative study of different techniques for the sterilization of poly-L-lactide electrospun microfibers: effectiveness vs. material degradation. The International journal of artificial organs, 33 2, 76-85

Spadaccio, Cristiano; Chachques, Emmanuel; Chello, Massimo; Covino, Elvio; Chachques, Juan C; Genovese, Jorge 2010. Predifferentiated adult stem cells and matrices for cardiac cell therapy. Asian cardiovascular & thoracic annals, 18 1, 79-87

Spadaccio, Cristiano; Pollari, Francesco; Casacalenda, Adele; Alfano, Gennaro; Genovese, Jorge; Covino, Elvio; Chello, Massimo 2010. Atorvastatin increases the number of endothelial progenitor cells after cardiac surgery: a randomized control study. Journal of cardiovascular pharmacology, 55 1, 30-8

Spadaccio, Cristiano; Rainer, Alberto; Centola, Matteo; Trombetta, Marcella; Chello, Massimo; Lusini, Mario; Covino, Elvio; Toyoda, Yoshiya; Genovese, Jorge A 2010. Heparin-releasing scaffold for stem cells: a differentiating device for vascular aims. Regenerative medicine, 5 4, 645-57

Spadaccio, Cristiano; Rainer, Alberto; De Porcellinis, Stefano; Centola, Matteo; De Marco, Federico; Chello, Massimo; Trombetta, Marcella; Genovese, Jorge A 2010. A G-CSF functionalized PLLA scaffold for wound repair: An in vitro preliminary study. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2010 , 843-6

Chello, Massimo; Spadaccio, Cristiano; Lusini, Mario; Covino, Elvio; Blarzino, Carla; De Marco, Federico; Di Domenico, Fabio; Coccia, Raffaella 2009. Advanced glycation end products in diabetic patients with optimized glycaemic control and their effects on endothelial reactivity: possible implications in venous graft failure. Diabetes/metabolism research and reviews, 25 5, 420-6

Genovese, Jorge A; Spadaccio, Cristiano; Chachques, Emmanuel; Schussler, Olivier; Carpentier, Alain; Chachques, Juan C; Patel, Amit N 2009. Cardiac pre-differentiation of human mesenchymal stem cells by electrostimulation. Frontiers in bioscience (Landmark edition), 14 8, 2996-3002

Genovese, Jorge A; Spadaccio, Cristiano; Rivello, Hernan Garcia; Toyoda, Yoshiya; Patel, Amit N 2009. Electrostimulated bone marrow human mesenchymal stem cells produce follistatin. Cytotherapy, 11 4, 448-56

Spadaccio, Cristiano; Chello, Massimo; Trombetta, Marcella; Rainer, Alberto; Toyoda, Yoshiya; Genovese, Jorge A 2009. Drug releasing systems in cardiovascular tissue engineering. Journal of cellular and molecular medicine, 13 3, 422-39

Spadaccio, Cristiano; Rainer, Alberto; Trombetta, Marcella; Vadalá, Gianluca; Chello, Massimo; Covino, Elvio; Denaro, Vincenzo; Toyoda, Yoshiya; Genovese, Jorge A 2009. Poly-L-lactic acid/hydroxyapatite electrospun nanocomposites induce chondrogenic differentiation of human MSC. Annals of biomedical engineering, 37 7, 1376-89

Chello, Massimo; Spadaccio, Cristiano; Patti, Giuseppe; Lusini, Mario; Barbato, Raffaele; Goffredo, Costanza; Di Sciascio, Germano; Covino, Elvio 2008. Simvastatin reduces platelet-endocardium adhesion in atrial fibrillation. Atherosclerosis, 197 2, 588-95

Genovese, Jorge A; Spadaccio, Cristiano; Langer, Jason; Habe, Jaclyn; Jackson, Johnna; Patel, Amit N 2008. Electrostimulation induces cardiomyocyte predifferentiation of fibroblasts. Biochemical and biophysical research communications, 370 3, 450-5

Chello, Massimo; Anselmi, Amedeo; Spadaccio, Cristiano; Patti, Giuseppe; Goffredo, Costanza; Di Sciascio, Germano; Covino, Elvio 2007. Simvastatin increases neutrophil apoptosis and reduces inflammatory reaction after coronary surgery. The Annals of thoracic surgery, 83 4, 1374-80

Chello, Massimo; Lusini, Mario; Spadaccio, Cristiano; Covino, Elvio 2007. Dysphagia soon after off-pump coronary surgery: the single suture technique. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 32 4, 667-8

Coccia, Raffaella; Spadaccio, Cristiano; Foppoli, Cesira; Perluigi, Marzia; Covino, Elvio; Lusini, Mario; Chello, Massimo 2007. The effect of simvastatin on erythrocyte membrane fluidity during oxidative stress induced by cardiopulmonary bypass: a randomized controlled study. Clinical therapeutics, 29 8, 1706-17

Patel, Amit N; Spadaccio, Cristiano; Kuzman, Michael; Park, Eulsoon; Fischer, David W; Stice, Steven L; Mullangi, Chandra; Toma, Catalin 2007. Improved cell survival in infarcted myocardium using a novel combination transmyocardial laser and cell delivery system. Cell transplantation, 16 9, 899-905

Chello, Massimo; Spadaccio, Cristiano; Anselmi, Amedeo; Patti, Giuseppe; Lusini, Mario; Di Sciascio, Germano; Covino, Elvio 2006. Simvastatin reduces CD40 expression in an experimental model of early arterialization of saphenous vein graft. The Journal of surgical research, 136 2, 302-8

Nappi, Francesco; Spadaccio, Cristiano; Acar, Christophe; El-Hamamsy, Ismail . Lights and Shadows on the Ross Procedure: Biological Solutions for Biological Problems. Seminars in thoracic and cardiovascular surgery, 32 4, 815-822

Spadaccio, Cristiano; Nappi, Francesco; Sablayrolles, Jean-Louis; Sutherland, Fraser W H . TAVR vs SAVR: Rising Expectations and Changing Indications for Surgery in Response to PARTNER II. Seminars in thoracic and cardiovascular surgery, 29 1, 8-11