Education/CredentialsFellowship in Pediatric Surgery: Baylor College of Medicine, Texas Children's Hospital of HoustonGeneral Surgery Residency: University of CincinnatiResearch Fellow in Pediatric Surgery: Cincinnati Children's Hospital Medical CenterECMO Fellowship: Cincinnati Children's Hospital Medical CenterMedical Degree: University of CincinnatiMaster's Degree: University of Cincinnati (Physiology and Biophysics)Bachelor's Degree: Miami University - Oxford Contact Information Childrens Hospital Bldg R Office 513-636-8318 Email helmraml@ucmail.uc.edu Research InterestsShort Bowel Syndrome, Intestinal Stem Cell Research Peer Reviewed Publications Bouffi, Carine; Wikenheiser-Brokamp, Kathryn A; Chaturvedi, Praneet; Sundaram, Nambirajan; Goddard, Gillian R; Wunderlich, Mark; Brown, Nicole E; Staab, Janet F; Latanich, Rachel; Zachos, Nicholas C; Holloway, Emily M; Mahe, Maxime M; Poling, Holly M; Vales, Simon; Fisher, Garrett W; Spence, Jason R; Mulloy, James C; Zorn, Aaron M; Wells, James M; Helmrath, Michael A 2023. In vivo development of immune tissue in human intestinal organoids transplanted into humanized mice. Nature biotechnology, 41 6, 824-831Gil, Lindsay A; Lutz, Carley M; Dillon, Patrick A; Downard, Cynthia D; Ehrlich, Peter F; Fallat, Mary E; Fraser, Jason D; Grabowski, Julia E; Helmrath, Michael A; Hertweck, S Paige; Hirschl, Ronald B; Kabre, Rashmi; Lal, Dave R; Landman, Matthew P; Lawrence, Amy E; Leys, Charles M; Mak, Grace Z; Markel, Troy A; Raiji, Manish T; Rymeski, Beth; Saito, Jacqueline M; Sato, Thomas T; St Peter, Shawn D; Stafford, Linda M Cherney; Deans, Katherine J; Minneci, Peter C; Hewitt, Geri D; Aldrink, Jennifer H 2023. Use and Accuracy of Intraoperative Frozen Section Analysis for Ovarian Masses in Children and Adolescents. Journal of pediatric and adolescent gynecology, 36 2, 155-159Marquart, John P; Bowder, Alexis N; Bence, Christina M; St Peter, Shawn D; Gadepalli, Samir K; Sato, Thomas T; Szabo, Aniko; Minneci, Peter C; Hirschl, Ronald B; Rymeski, Beth A; Downard, Cynthia D; Markel, Troy A; Deans, Katherine J; Fallat, Mary E; Fraser, Jason D; Grabowski, Julia E; Helmrath, Michael A; Kabre, Rashmi D; Kohler, Jonathan E; Landman, Matthew P; Lawrence, Amy E; Leys, Charles M; Mak, Grace Z; Port, Elissa; Saito, Jacqueline; Silverberg, Jared; Slidell, Mark B; Wright, Tiffany N; Lal, Dave R 2023. Thoracoscopy versus thoracotomy for esophageal atresia and tracheoesophageal fistula: Outcomes from the Midwest Pediatric Surgery Consortium. Journal of pediatric surgery, 58 1, 27-33Moran-Lev, Hadar; Kocoshis, Samuel A; Oliveira, Stephanie B; Helmrath, Michael; Cole, Conrad R 2023. Chronic Mucosal Inflammation in Pediatric Intestinal Failure Patients- a Unique Phenomenon. Journal of pediatric gastroenterology and nutrition, , O'Connell, Amy E; Raveenthiraraj, Sathuwarman; Adegboye, Comfort; Qi, Wanshu; Khetani, Radhika S; Singh, Akaljot; Sundaram, Nambirajam; Emeonye, Chidera; Lin, Jasmine; Goldsmith, Jeffrey D; Thiagarajah, Jay R; Carlone, Diana L; Turner, Jerrold R; Agrawal, Pankaj B; Helmrath, Michael; Breault, David T 2023. WNT2B Deficiency Causes Increased Susceptibility to Colitis in Mice and Impairs Intestinal Epithelial Development in Humans. bioRxiv : the preprint server for biology, , Singh, Akaljot; Poling, Holly M; Chaturvedi, Praneet; Thorner, Konrad; Sundaram, Nambirajan; Kechele, Daniel O; Childs, Charlie J; McCauley, Heather A; Fisher, Garrett W; Brown, Nicole E; Spence, Jason R; Wells, James M; Helmrath, Michael A 2023. Transplanted human intestinal organoids: a resource for modeling human intestinal development. Development (Cambridge, England), 150 9, Zeller, Meg H; Strong, Heather; Reiter-Purtill, Jennifer; Jenkins, Todd M; Mitchell, James E; Michalsky, Marc P; Helmrath, Michael A 2023. Marijuana, e-cigarette, and tobacco product use in young adults who underwent pediatric bariatric surgery. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 19 5, 512-521Bowder, Alexis N; Bence, Christina M; Rymeski, Beth A; Gadepalli, Samir K; Sato, Thomas T; Szabo, Aniko; Arendonk, Kyle Van; Minneci, Peter C; Downard, Cynthia D; Hirschl, Ronald B; Markel, Troy; Courtney, Cathleen M; Deans, Katherine J; Fallat, Mary E; Fraser, Jason D; Grabowski, Julia E; Helmrath, Michael A; Kabre, Rashmi D; Kohler, Jonathan E; Landman, Matthew P; Lawrence, Amy E; Leys, Charles M; Mak, Grace; Port, Elissa; Saito, Jacqueline; Silverberg, Jared; Slidell, Mark B; St Peter, Shawn D; Troutt, Misty; Wright, Tiffany N; Lal, Dave R 2022. Acid suppression duration does not alter anastomotic stricture rates after esophageal atresia with distal tracheoesophageal fistula repair: A prospective multi-institutional cohort study. Journal of pediatric surgery, 57 6, 975-980Capeling, Meghan M; Huang, Sha; Childs, Charlie J; Wu, Joshua H; Tsai, Yu-Hwai; Wu, Angeline; Garg, Neil; Holloway, Emily M; Sundaram, Nambirajan; Bouffi, Carine; Helmrath, Michael; Spence, Jason R 2022. Suspension culture promotes serosal mesothelial development in human intestinal organoids. Cell reports, 38 7, 110379Chakrabarti, Jayati; Dua-Awereh, Martha; Schumacher, Michael; Engevik, Amy; Hawkins, Jennifer; Helmrath, Michael A; Zavros, Yana 2022. Sonic Hedgehog acts as a macrophage chemoattractant during regeneration of the gastric epithelium. NPJ Regenerative medicine, 7 1, 3Decker, Kristina M; Reiter-Purtill, Jennifer; Bejarano, Carolina M; Goldschmidt, Andrea B; Mitchell, James E; Jenkins, Todd M; Helmrath, Michael; Inge, Thomas H; Michalsky, Marc P; Zeller, Meg H 2022. Psychosocial predictors of problematic eating in young adults who underwent adolescent bariatric surgery. Obesity science & practice, 8 5, 545-555Dekonenko, Charlene; Fraser, Jason D; Deans, Katherine; Fallat, Mary E; Helmrath, Michael; Kabre, Rashmi; Leys, Charles M; Burns, R Cartland; Corkum, Kristine; Dillon, Patrick A; Downard, Cynthia; Wright, Tiffany N; Gadepalli, Samir K; Grabowski, Julia; Hernandez, Edward; Hirschl, Ronald; Johnson, Kevin N; Kohler, Jonathan; Landman, Matthew P; Landisch, Rachel M; Lawrence, Amy E; Mak, Grace Z; Minneci, Peter; Rymeski, Beth; Sato, Thomas T; Slater, Bethany J; Peter, St Shawn D 2022. Does Use of a Feeding Protocol Change Outcomes in Gastroschisis? A Report from the Midwest Pediatric Surgery Consortium. European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 32 2, 153-159Ding, Lin; Chakrabarti, Jayati; Sheriff, Sulaiman; Li, Qian; Thi Hong, Hahn Nguyen; Sontz, Ricky A; Mendoza, Zoe E; Schreibeis, Amanda; Helmrath, Michael A; Zavros, Yana; Merchant, Juanita L 2022. Toll-like Receptor 9 Pathway Mediates Schlafen+-MDSC Polarization During Helicobacter-induced Gastric Metaplasias. Gastroenterology, 163 2, 411-425.e4Eicher, Alexandra K; Kechele, Daniel O; Sundaram, Nambirajan; Berns, H Matthew; Poling, Holly M; Haines, Lauren E; Sanchez, J Guillermo; Kishimoto, Keishi; Krishnamurthy, Mansa; Han, Lu; Zorn, Aaron M; Helmrath, Michael A; Wells, James M 2022. Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells. Cell stem cell, 29 1, 36-51.e6Engwall-Gill, Abigail J; Chan, Sherwin S; Boyd, Kevin P; Saito, Jacqueline M; Fallat, Mary E; St Peter, Shawn D; Bolger-Theut, Stephanie; Crotty, Eric J; Green, Jared R; Hulett Bowling, Rebecca L; Kumbhar, Sachin S; Rattan, Mantosh S; Young, Cody M; Canner, Joseph K; Deans, Katherine J; Gadepalli, Samir K; Helmrath, Michael A; Hirschl, Ronald B; Kabre, Rashmi; Lal, Dave R; Landman, Matthew P; Leys, Charles M; Mak, Grace Z; Minneci, Peter C; Wright, Tiffany N; Kunisaki, Shaun M 2022. Accuracy of Chest Computed Tomography in Distinguishing Cystic Pleuropulmonary Blastoma From Benign Congenital Lung Malformations in Children. JAMA network open, 5 6, e2219814Fraser, James A; Deans, Katherine J; Fallat, Mary E; Helmrath, Michael; Kabre, Rashmi; Leys, Charles M; Markel, Troy A; Dillon, Patrick A; Downard, Cynthia; Wright, Tiffany N; Gadepalli, Samir K; Grabowski, Julia E; Hirschl, Ronald; Johnson, Kevin N; Kohler, Jonathan E; Landman, Matthew P; Mak, Grace Z; Minneci, Peter C; Rymeski, Beth; Sato, Thomas T; Slater, Bethany J; Peter, Shawn D St; Fraser, Jason D 2022. Evaluating the risk of peri-umbilical hernia after sutured or sutureless gastroschisis closure. Journal of pediatric surgery, 57 12, 786-791Kunisaki, Shaun M; Saito, Jacqueline M; Fallat, Mary E; Peter, Shawn D St; Lal, Dave R; Karmakar, Monita; Deans, Katherine J; Gadepalli, Samir K; Hirschl, Ronald B; Minneci, Peter C; Helmrath, Michael A 2022. Fetal Risk Stratification and Outcomes in Children with Prenatally Diagnosed Lung Malformations: Results from a Multi-Institutional Research Collaborative. Annals of surgery, 276 5, e622-e630McNelis, Kera; Poindexter, Anne; Goddard, Gillian; Riddle, Stefanie; Wessel, Jacqueline; Helmrath, Michael 2022. Body Composition of Infants With Congenital Gastroschisis. Journal of pediatric gastroenterology and nutrition, 74 2, e35-e38Minneci, Peter C; Hade, Erinn M; Gil, Lindsay A; Metzger, Gregory A; Saito, Jacqueline M; Mak, Grace Z; Hirschl, Ronald B; Gadepalli, Samir; Helmrath, Michael A; Leys, Charles M; Sato, Thomas T; Lal, Dave R; Landman, Matthew P; Kabre, Rashmi; Fallat, Mary E; Cooper, Jennifer N; Deans, Katherine J 2022. Demographic and Clinical Characteristics Associated With the Failure of Nonoperative Management of Uncomplicated Appendicitis in Children: Secondary Analysis of a Nonrandomized Clinical Trial. JAMA network open, 5 5, e229712Pitstick, Amy L; Poling, Holly M; Sundaram, Nambirajan; Lewis, Phillip L; Kechele, Daniel O; Sanchez, J Guillermo; Scott, Melissa A; Broda, Taylor R; Helmrath, Michael A; Wells, James M; Mayhew, Christopher N 2022. Aggregation of cryopreserved mid-hindgut endoderm for more reliable and reproducible hPSC-derived small intestinal organoid generation. Stem cell reports, 17 8, 1889-1902Rosselot, Andrew E; Park, Miri; Kim, Mari; Matsu-Ura, Toru; Wu, Gang; Flores, Danilo E; Subramanian, Krithika R; Lee, Suengwon; Sundaram, Nambirajan; Broda, Taylor R; McCauley, Heather A; Hawkins, Jennifer A; Chetal, Kashish; Salomonis, Nathan; Shroyer, Noah F; Helmrath, Michael A; Wells, James M; Hogenesch, John B; Moore, Sean R; Hong, Christian I 2022. Ontogeny and function of the circadian clock in intestinal organoids. The EMBO journal, 41 2, e106973Arora, Kavisha; Yang, Fanmuyi; Brewington, John; McPhail, Gary; Cortez, Alexander R; Sundaram, Nambirajan; Ramananda, Yashaswini; Ogden, Herbert; Helmrath, Michael; Clancy, John P; Naren, Anjaparavanda P 2021. Patient personalized translational tools in cystic fibrosis to transform data from bench to bed-side and back. American journal of physiology. Gastrointestinal and liver physiology, 320 6, G1123-G1130Bence, Christina M; Rymeski, Beth; Gadepalli, Samir; Sato, Thomas T; Minneci, Peter C; Downard, Cynthia; Hirschl, Ronald B; Amin, Ruchi A; Burns, R Cartland; Cherney-Stafford, Linda; Courtney, Cathleen M; Deans, Katherine J; Fallat, Mary E; Fraser, Jason D; Grabowski, Julia E; Helmrath, Michael A; Kabre, Rashmi D; Kohler, Jonathan E; Landman, Matthew P; Lawrence, Amy E; Leys, Charles M; Mak, Grace Z; Port, Elissa; Saito, Jacqueline M; Silverberg, Jared; Slidell, Mark B; St Peter, Shawn D; Troutt, Misty; Walker, Sarah; Wright, Tiffany; Lal, Dave R 2021. Clinical outcomes following implementation of a management bundle for esophageal atresia with distal tracheoesophageal fistula. Journal of pediatric surgery, 56 1, 47-54Chakrabarti, Jayati; Koh, Vivien; Steele, Nina; Hawkins, Jennifer; Ito, Yoshiaki; Merchant, Juanita L; Wang, Jiang; Helmrath, Michael A; Ahmad, Syed A; So, Jimmy Bok Yan; Yong, Wei Peng; Zavros, Yana 2021. Disruption of Her2-Induced PD-L1 Inhibits Tumor Cell Immune Evasion in Patient-Derived Gastric Cancer Organoids. Cancers, 13 24, Chan, Calvin C; Harley, Isaac T W; Pfluger, Paul T; Trompette, Aurelien; Stankiewicz, Traci E; Allen, Jessica L; Moreno-Fernandez, Maria E; Damen, Michelle S M A; Oates, Jarren R; Alarcon, Pablo C; Doll, Jessica R; Flick, Matthew J; Flick, Leah M; Sanchez-Gurmaches, Joan; Mukherjee, Rajib; Karns, Rebekah; Helmrath, Michael; Inge, Thomas H; Weisberg, Stuart P; Pamp, Sünje J; Relman, David A; Seeley, Randy J; Tschöp, Matthias H; Karp, Christopher L; Divanovic, Senad 2021. A BAFF/APRIL axis regulates obesogenic diet-driven weight gain. Nature communications, 12 1, 2911Criss, Zachary K; Bhasin, Nobel; Di Rienzi, Sara C; Rajan, Anubama; Deans-Fielder, Kali; Swaminathan, Ganesh; Kamyabi, Nabiollah; Zeng, Xi-Lei; Doddapaneni, Harsha; Menon, Vipin K; Chakravarti, Deepavali; Estrella, Clarissa; Yu, Xiaomin; Patil, Ketki; Petrosino, Joseph F; Fleet, James C; Verzi, Michael P; Christakos, Sylvia; Helmrath, Michael A; Arimura, Sumimasa; DePinho, Ronald A; Britton, Robert A; Maresso, Anthony W; Grande-Allen, K Jane; Blutt, Sarah E; Crawford, Sue E; Estes, Mary K; Ramani, Sasirekha; Shroyer, Noah F 2021. Drivers of transcriptional variance in human intestinal epithelial organoids. Physiological genomics, 53 11, 486-508Dekonenko, Charlene; Fraser, Jason D; Deans, Katherine J; Fallat, Mary E; Helmrath, Michael; Kabre, Rashmi; Leys, Charles M; Burns, R Cartland; Corkumd, Kristine; Dillon, Patrick A; Downard, Cynthia; Wright, Tiffany N; Gadepalli, Samir K; Grabowski, Julia E; Hernandez, Edward; Hirschl, Ronald; Johnson, Kevin N; Kohler, Jonathan E; Landman, Matthew P; Landisch, Rachel M; Lawrence, Amy E; Mak, Grace Z; Minneci, Peter C; Rymeski, Beth; Sato, Thomas T; Slater, Bethany J; St Peter, Shawn D 2021. Outcomes in gastroschisis: expectations in the postnatal period for simple vs complex gastroschisis. Journal of perinatology : official journal of the California Perinatal Association, 41 7, 1755-1759Goddard, Gillian R; McNelis, Kera; Poindexter, Anne; Jenkins, Todd; Wessel, Jacqueline; Nathan, Amy T; Helmrath, Michael A; Poindexter, Brenda 2021. Quality Improvement Efforts Reduce Incidence of Surgical Necrotizing Enterocolitis and Related Deaths. American journal of perinatology, 38 13, 1386-1392Kasendra, Magdalena; Troutt, Misty; Broda, Taylor; Bacon, W Clark; Wang, Timothy C; Niland, Joyce C; Helmrath, Michael A 2021. Intestinal organoids: roadmap to the clinic. American journal of physiology. Gastrointestinal and liver physiology, 321 1, G1-G10Koh, Vivien; Chakrabarti, Jayati; Torvund, Meaghan; Steele, Nina; Hawkins, Jennifer A; Ito, Yoshiaki; Wang, Jiang; Helmrath, Michael A; Merchant, Juanita L; Ahmed, Syed A; Shabbir, Asim; Yan So, Jimmy Bok; Yong, Wei Peng; Zavros, Yana 2021. Hedgehog transcriptional effector GLI mediates mTOR-Induced PD-L1 expression in gastric cancer organoids. Cancer letters, 518 , 59-71Kunisaki, Shaun M; Lal, Dave R; Saito, Jacqueline M; Fallat, Mary E; St Peter, Shawn D; Fox, Zachary D; Heider, Amer; Chan, Sherwin S; Boyd, Kevin P; Burns, R Cartland; Deans, Katherine J; Gadepalli, Samir K; Hirschl, Ronald B; Kabre, Rashmi; Landman, Matthew P; Leys, Charles M; Mak, Grace Z; Minneci, Peter C; Wright, Tiffany N; Helmrath, Michael A 2021. Pleuropulmonary Blastoma in Pediatric Lung Lesions. Pediatrics, 147 4, Lim, Irene Isabel P; Cushing, Christopher C; Jenkins, Todd; Troutt, Misty; Zeller, Margaret H; Hossain, Monir; Rymeski, Beth; Helmrath, Michael; Frischer, Jason S 2021. Prospective quality of life outcomes in pediatric fecal incontinence following bowel management. Journal of pediatric surgery, 56 8, 1459-1464McNelis, Kera; Goddard, Gillian; Jenkins, Todd; Poindexter, Anne; Wessel, Jacqueline; Helmrath, Michael; Poindexter, Brenda 2021. Delay in achieving enteral autonomy and growth outcomes in very low birth weight infants with surgical necrotizing enterocolitis. Journal of perinatology : official journal of the California Perinatal Association, 41 1, 150-156Moreno-Fernandez, Maria E; Giles, Daniel A; Oates, Jarren R; Chan, Calvin C; Damen, Michelle S M A; Doll, Jessica R; Stankiewicz, Traci E; Chen, Xiaoting; Chetal, Kashish; Karns, Rebekah; Weirauch, Matthew T; Romick-Rosendale, Lindsey; Xanthakos, Stavra A; Sheridan, Rachel; Szabo, Sara; Shah, Amy S; Helmrath, Michael A; Inge, Thomas H; Deshmukh, Hitesh; Salomonis, Nathan; Divanovic, Senad 2021. PKM2-dependent metabolic skewing of hepatic Th17 cells regulates pathogenesis of non-alcoholic fatty liver disease. Cell metabolism, 33 6, 1187-1204.e9Shah, Amy S; Helmrath, Michael A; Inge, Thomas H; Xanthakos, Stavra A; Kelsey, Megan M; Jenkins, Todd; Trout, Andrew T; Browne, Lorna; Nadeau, Kristen J 2021. Study protocol: a prospective controlled clinical trial to assess surgical or medical treatment for paediatric type 2 diabetes (ST2OMP). BMJ open, 11 8, e047766Weller, Jennine H; Peter, Shawn D St; Fallat, Mary E; Saito, Jacqueline M; Burns, Cartland R; Deans, Katherine J; Fraser, Jason D; Gadepalli, Samir K; Helmrath, Michael A; Hirschl, Ronald B; Kabre, Rashmi; Lal, Dave R; Landman, Matthew P; Leys, Charles M; Mak, Grace Z; Minneci, Peter C; Wright, Tiffany N; Kunisaki, Shaun M 2021. Thoracoscopic versus open lobectomy in infants with congenital lung malformations: A multi-institutional propensity score analysis. Journal of pediatric surgery, 56 12, 2148-2156Chan, Calvin C; Damen, Michelle S M A; Moreno-Fernandez, Maria E; Stankiewicz, Traci E; Cappelletti, Monica; Alarcon, Pablo C; Oates, Jarren R; Doll, Jessica R; Mukherjee, Rajib; Chen, Xiaoting; Karns, Rebekah; Weirauch, Matthew T; Helmrath, Michael A; Inge, Thomas H; Divanovic, Senad 2020. Type I interferon sensing unlocks dormant adipocyte inflammatory potential. Nature communications, 11 1, 2745Dewberry, Lindel C; Jalivand, Anahita; Gupta, Resmi; Jenkins, Todd M; Beamish, Andrew; Inge, Thomas H; Courcoulas, Anita; Helmrath, Michael; Brandt, Mary L; Harmon, Carroll M; Chen, Mike; Dixon, John B; Zeller, Margaret; Michalsky, Marc P 2020. Weight Loss and Health Status 5 Years After Adjustable Gastric Banding in Adolescents. Obesity surgery, 30 6, 2388-2394Fraser, Jason D; Deans, Katherine J; Fallat, Mary E; Helmrath, Michael A; Kabre, Rashmi; Leys, Charles M; Burns, R Cartland; Corkum, Kristine; Dillon, Patrick A; Downard, Cynthia D; Gadepalli, Samir K; Grabowski, Julia E; Hernandez, Edward; Hirschl, Ronald B; Johnson, Kevin N; Kohler, Jonathan E; Landman, Matthew P; Landisch, Rachel M; Lawrence, Amy E; Mak, Grace Z; Minneci, Peter C; Rymeski, Beth; Sato, Thomas T; Scannell, Madeline; Slater, Bethany J; Wilkinson, Kathryn H; Wright, Tiffany N; St Peter, Shawn D 2020. Sutureless vs sutured abdominal wall closure for gastroschisis: Operative characteristics and early outcomes from the Midwest Pediatric Surgery Consortium. Journal of pediatric surgery, 55 11, 2284-2288Kunisaki, Shaun M; Saito, Jacqueline M; Fallat, Mary E; St Peter, Shawn D; Lal, Dave R; Johnson, Kevin N; Mon, Rodrigo A; Adams, Cheryl; Aladegbami, Bola; Bence, Christina; Burns, R Cartland; Corkum, Kristine S; Deans, Katherine J; Downard, Cynthia D; Fraser, Jason D; Gadepalli, Samir K; Helmrath, Michael A; Kabre, Rashmi; Landman, Matthew P; Leys, Charles M; Linden, Allison F; Lopez, Joseph J; Mak, Grace Z; Minneci, Peter C; Rademacher, Brooks L; Shaaban, Aimen; Walker, Sarah K; Wright, Tiffany N; Hirschl, Ronald B 2020. Development of a multi-institutional registry for children with operative congenital lung malformations. Journal of pediatric surgery, 55 7, 1313-1318Lamoshi, Abdulrouf; Chernoguz, Artur; Harmon, Carroll M; Helmrath, Michael 2020. Complications of bariatric surgery in adolescents. Seminars in pediatric surgery, 29 1, 150888Leys, Charles M; Hirschl, Ronald B; Kohler, Jonathan E; Cherney-Stafford, Linda; Marka, Nicholas; Fallat, Mary E; Gadepalli, Samir K; Fraser, Jason D; Grabowski, Julia; Burns, R Cartland; Downard, Cynthia D; Foley, David S; Halleran, Devin R; Helmrath, Michael A; Kabre, Rashmi; Knezevich, Michelle S; Lal, Dave R; Landman, Matthew P; Lawrence, Amy E; Mak, Grace Z; Minneci, Peter C; Musili, Ninette; Rymeski, Beth; Saito, Jacqueline M; Sato, Thomas T; St Peter, Shawn D; Warner, Brad W; Ostlie, Daniel J 2020. Changing the Paradigm for Management of Pediatric Primary Spontaneous Pneumothorax: A Simple Aspiration Test Predicts Need for Operation. Journal of pediatric surgery, 55 1, 169-175McCauley, Heather A; Matthis, Andrea L; Enriquez, Jacob R; Nichol, Jonah T; Sanchez, J Guillermo; Stone, William J; Sundaram, Nambirajan; Helmrath, Michael A; Montrose, Marshall H; Aihara, Eitaro; Wells, James M 2020. Enteroendocrine cells couple nutrient sensing to nutrient absorption by regulating ion transport. Nature communications, 11 1, 4791Minneci, Peter C; Hade, Erinn M; Lawrence, Amy E; Sebastião, Yuri V; Saito, Jacqueline M; Mak, Grace Z; Fox, Christa; Hirschl, Ronald B; Gadepalli, Samir; Helmrath, Michael A; Kohler, Jonathan E; Leys, Charles M; Sato, Thomas T; Lal, Dave R; Landman, Matthew P; Kabre, Rashmi; Fallat, Mary E; Cooper, Jennifer N; Deans, Katherine J 2020. Association of Nonoperative Management Using Antibiotic Therapy vs Laparoscopic Appendectomy With Treatment Success and Disability Days in Children With Uncomplicated Appendicitis. JAMA, 324 6, 581-593Pradhan, Suman; Karve, Sayali S; Weiss, Alison A; Hawkins, Jennifer; Poling, Holly M; Helmrath, Michael A; Wells, James M; McCauley, Heather A 2020. Tissue Responses to Shiga Toxin in Human Intestinal Organoids. Cellular and molecular gastroenterology and hepatology, 10 1, 171-190Shah, Amy S; Nadeau, Kristen J; Helmrath, Michael A; Inge, Thomas H; Xanthakos, Stavra A; Kelsey, Megan M 2020. Metabolic outcomes of surgery in youth with type 2 diabetes. Seminars in pediatric surgery, 29 1, 150893Singh, Akaljot; Poling, Holly M; Spence, Jason R; Wells, James M; Helmrath, Michael A 2020. Gastrointestinal organoids: a next-generation tool for modeling human development. American journal of physiology. Gastrointestinal and liver physiology, 319 3, G375-G381Singh, Akaljot; Poling, Holly M; Sundaram, Nambirajan; Brown, Nicole; Wells, James M; Helmrath, Michael A 2020. Evaluation of transplantation sites for human intestinal organoids. PloS one, 15 8, e0237885Sitzman, Thomas J; Carle, Adam C; Lundberg, Jaclyn N; Heaton, Pamela C; Helmrath, Michael A; Trotman, Carroll-Ann; Britto, Maria T 2020. Marked Variation Exists Among Surgeons and Hospitals in the Use of Secondary Cleft Lip Surgery. The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 57 2, 198-207Vales, Simon; Poling, Holly M; Sundaram, Nambirajan; Helmrath, Michael A; Mahe, Maxime M 2020. In Vivo Human PSC-Derived Intestinal Organoids to Study Stem Cell Maintenance. Methods in molecular biology (Clifton, N.J.), 2171 , 201-214Valvi, Damaskini; Walker, Douglas I; Inge, Thomas; Bartell, Scott M; Jenkins, Todd; Helmrath, Michael; Ziegler, Thomas R; La Merrill, Michele A; Eckel, Sandrah P; Conti, David; Liang, Yongliang; Jones, Dean P; McConnell, Rob; Chatzi, Leda 2020. Environmental chemical burden in metabolic tissues and systemic biological pathways in adolescent bariatric surgery patients: A pilot untargeted metabolomic approach. Environment international, 143 , 105957Xanthakos, Stavra A; Khoury, Jane C; Inge, Thomas H; Jenkins, Todd M; Modi, Avani C; Michalsky, Marc P; Chen, Mike K; Courcoulas, Anita P; Harmon, Carroll M; Brandt, Mary L; Helmrath, Michael A; Kalkwarf, Heidi J 2020. Nutritional Risks in Adolescents After Bariatric Surgery. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 18 5, 1070-1081.e5Bout-Tabaku, Sharon; Gupta, Resmi; Jenkins, Todd M; Ryder, Justin R; Baughcum, Amy E; Jackson, Rebecca D; Inge, Thomas H; Dixon, John B; Helmrath, Michael A; Courcoulas, Anita P; Mitchell, James E; Harmon, Carroll M; Xie, Changchun; Michalsky, Marc P 2019. Musculoskeletal Pain, Physical Function, and Quality of Life After Bariatric Surgery. Pediatrics, 144 6, Capeling, Meghan M; Czerwinski, Michael; Huang, Sha; Tsai, Yu-Hwai; Wu, Angeline; Nagy, Melinda S; Juliar, Benjamin; Sundaram, Nambirajan; Song, Yang; Han, Woojin M; Takayama, Shuichi; Alsberg, Eben; Garcia, Andres J; Helmrath, Michael; Putnam, Andrew J; Spence, Jason R 2019. Nonadhesive Alginate Hydrogels Support Growth of Pluripotent Stem Cell-Derived Intestinal Organoids. Stem cell reports, 12 2, 381-394Capurro, Mariana I; Greenfield, Laura K; Prashar, Akriti; Xia, Sunny; Abdullah, Majd; Wong, Harikesh; Zhong, Xi Zoe; Bertaux-Skeirik, Nina; Chakrabarti, Jayati; Siddiqui, Iram; O'Brien, Catherine; Dong, Xianping; Robinson, Lisa; Peek, Richard M; Philpott, Dana J; Zavros, Yana; Helmrath, Michael; Jones, Nicola L 2019. VacA generates a protective intracellular reservoir for Helicobacter pylori that is eliminated by activation of the lysosomal calcium channel TRPML1. Nature microbiology, 4 8, 1411-1423Goddard, Gillian R; Kotagal, Meera; Jenkins, Todd M; Kollar, Linda M; Inge, Thomas H; Helmrath, Michael A 2019. Weight loss after sleeve gastrectomy in developmentally delayed adolescents and young adults. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 15 10, 1662-1667Holokai, Loryn; Chakrabarti, Jayati; Broda, Taylor; Chang, Julie; Hawkins, Jennifer A; Sundaram, Nambirajan; Wroblewski, Lydia E; Peek, Richard M; Wang, Jiang; Helmrath, Michael; Wells, James M; Zavros, Yana 2019. Increased Programmed Death-Ligand 1 is an Early Epithelial Cell Response to Helicobacter pylori Infection. PLoS pathogens, 15 1, e1007468Inge, Thomas H; Courcoulas, Anita P; Helmrath, Michael A 2019. Five-Year Outcomes of Gastric Bypass in Adolescents as Compared with Adults. Reply. The New England journal of medicine, 381 9, e17Inge, Thomas H; Courcoulas, Anita P; Jenkins, Todd M; Michalsky, Marc P; Brandt, Mary L; Xanthakos, Stavra A; Dixon, John B; Harmon, Carroll M; Chen, Mike K; Xie, Changchun; Evans, Mary E; Helmrath, Michael A 2019. Five-Year Outcomes of Gastric Bypass in Adolescents as Compared with Adults. The New England journal of medicine, 380 22, 2136-2145Kunisaki, Shaun M; Saito, Jacqueline M; Fallat, Mary E; St Peter, Shawn D; Kim, Aimee G; Johnson, Kevin N; Mon, Rodrigo A; Adams, Cheryl; Aladegbami, Bola; Bence, Christina; Burns, R Cartland; Corkum, Kristine S; Deans, Katherine J; Downard, Cynthia D; Fraser, Jason D; Gadepalli, Samir K; Helmrath, Michael A; Kabre, Rashmi; Lal, Dave R; Landman, Matthew P; Leys, Charles M; Linden, Allison F; Lopez, Joseph J; Mak, Grace Z; Minneci, Peter C; Rademacher, Brooks L; Shaaban, Aimen; Walker, Sarah K; Wright, Tiffany N; Hirschl, Ronald B 2019. Current operative management of congenital lobar emphysema in children: A report from the Midwest Pediatric Surgery Consortium. Journal of pediatric surgery, 54 6, 1138-1142Lal, Dave R; Gadepalli, Samir K; Downard, Cynthia D; Minneci, Peter C; Knezevich, Michelle; Chelius, Thomas H; Rapp, Cooper T; Billmire, Deborah; Bruch, Steven; Carland Burns, R; Deans, Katherine J; Fallat, Mary E; Fraser, Jason D; Grabowski, Julia; Hebel, Ferdynand; Helmrath, Michael A; Hirschl, Ronald B; Kabre, Rashmi; Kohler, Jonathan; Landman, Matthew P; Leys, Charles M; Mak, Grace Z; Ostlie, Daniel J; Raque, Jessica; Rymeski, Beth; Saito, Jacqueline M; St Peter, Shawn D; von Allmen, Daniel; Warner, Brad W; Sato, Thomas T 2019. Infants with esophageal atresia and right aortic arch: Characteristics and outcomes from the Midwest Pediatric Surgery Consortium. Journal of pediatric surgery, 54 4, 688-692Minneci, Peter C; Hade, Erinn M; Lawrence, Amy E; Saito, Jacqueline M; Mak, Grace Z; Hirschl, Ronald B; Gadepalli, Samir; Helmrath, Michael A; Leys, Charles M; Sato, Thomas T; Lal, Dave R; Landman, Matthew P; Kabre, Rashmi; Fallat, Mary E; Fischer, Beth A; Cooper, Jennifer N; Deans, Katherine J 2019. Multi-institutional trial of non-operative management and surgery for uncomplicated appendicitis in children: Design and rationale. Contemporary clinical trials, 83 , 10-17Minneci, Peter C; Kabre, Rashmi S; Mak, Grace Z; Halleran, Devin R; Cooper, Jennifer N; Afrazi, Amin; Calkins, Casey M; Corkum, Kristine; Downard, Cynthia D; Ehrlich, Peter; Fraser, Jason D; Gadepalli, Samir K; Helmrath, Michael A; Kohler, Jonathan E; Landisch, Rachel; Landman, Matthew P; Lee, Constance; Leys, Charles M; Lodwick, Daniel L; McLeod, Jennifer; Mon, Rodrigo; McClure, Beth; Rymeski, Beth; Saito, Jacqueline M; Sato, Thomas T; St Peter, Shawn D; Wood, Richard; Levitt, Marc A; Deans, Katherine J 2019. Can fecal continence be predicted in patients born with anorectal malformations? Journal of pediatric surgery, 54 6, 1159-1163Múnera, Jorge O; Sundaram, Nambirajan; Rankin, Scott A; Hill, David; Watson, Carey; Mahe, Maxime; Vallance, Jefferson E; Shroyer, Noah F; Sinagoga, Katie L; Zarzoso-Lacoste, Adrian; Hudson, Jonathan R; Howell, Jonathan C; Chatuvedi, Praneet; Spence, Jason R; Shannon, John M; Zorn, Aaron M; Helmrath, Michael A; Wells, James M 2019. Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling. Cell stem cell, 24 5, 829Noah, Taeko K; Knoop, Kathryn A; McDonald, Keely G; Gustafsson, Jenny K; Waggoner, Lisa; Vanoni, Simone; Batie, Matthew; Arora, Kavisha; Naren, Anjaparavanda P; Wang, Yui-Hsi; Lukacs, Nicholas W; Munitz, Ariel; Helmrath, Michael A; Mahe, Maxime M; Newberry, Rodney D; Hogan, Simon P 2019. IL-13-induced intestinal secretory epithelial cell antigen passages are required for IgE-mediated food-induced anaphylaxis. The Journal of allergy and clinical immunology, 144 4, 1058-1073.e3Sitzman, Thomas J; Carle, Adam C; Heaton, Pamela C; Helmrath, Michael A; Britto, Maria T 2019. Five-Fold Variation Among Surgeons and Hospitals in the Use of Secondary Palate Surgery. The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 56 5, 586-594Steele, Nina G; Chakrabarti, Jayati; Wang, Jiang; Biesiada, Jacek; Holokai, Loryn; Chang, Julie; Nowacki, Lauren M; Hawkins, Jennifer; Mahe, Maxime; Sundaram, Nambirajan; Shroyer, Noah; Medvedovic, Mario; Helmrath, Michael; Ahmad, Syed; Zavros, Yana 2019. An Organoid-Based Preclinical Model of Human Gastric Cancer. Cellular and molecular gastroenterology and hepatology, 7 1, 161-184Brode, Cassie; Ratcliff, Megan; Reiter-Purtill, Jennifer; Hunsaker, Sanita; Helmrath, Michael; Zeller, Meg 2018. Predictors of Preoperative Program Non-Completion in Adolescents Referred for Bariatric Surgery. Obesity surgery, 28 9, 2853-2859Cortez, Alexander R; Poling, Holly M; Brown, Nicole E; Singh, Akaljot; Mahe, Maxime M; Helmrath, Michael A 2018. Transplantation of human intestinal organoids into the mouse mesentery: A more physiologic and anatomic engraftment site. Surgery, 164 4, 643-650Cushing, Christopher C; Threlkeld, Melody R S; Martinez-Leo, Bruno; Hall, Jennifer; Hossain, Monir; Dickie, Belinda H; Rymeski, Beth; Helmrath, Michael; Zeller, Meg H; Frischer, Jason S 2018. Initial development and validation of a fecal incontinence-specific quality of life measure. Journal of pediatric surgery, 53 6, 1148-1153Kelly, Daniel; Kotliar, Michael; Woo, Vivienne; Jagannathan, Sajjeev; Whitt, Jordan; Moncivaiz, Jessica; Aronow, Bruce J; Dubinsky, Marla C; Hyams, Jeffrey S; Markowitz, James F; Baldassano, Robert N; Stephens, Michael C; Walters, Thomas D; Kugathasan, Subra; Haberman, Yael; Sundaram, Nambirajan; Rosen, Michael J; Helmrath, Michael; Karns, Rebekah; Barski, Artem; Denson, Lee A; Alenghat, Theresa 2018. Microbiota-sensitive epigenetic signature predicts inflammation in Crohn's disease. JCI insight, 3 18, Lal, Dave R; Gadepalli, Samir K; Downard, Cynthia D; Ostlie, Daniel J; Minneci, Peter C; Swedler, Ruth M; Chelius, Thomas H; Cassidy, Laura; Rapp, Cooper T; Billmire, Deborah; Bruch, Steven; Burns, R Carland; Deans, Katherine J; Fallat, Mary E; Fraser, Jason D; Grabowski, Julia; Hebel, Ferdynand; Helmrath, Michael A; Hirschl, Ronald B; Kabre, Rashmi; Kohler, Jonathan; Landman, Matthew P; Leys, Charles M; Mak, Grace Z; Raque, Jessica; Rymeski, Beth; Saito, Jacqueline M; St Peter, Shawn D; von Allmen, Daniel; Warner, Brad W; Sato, Thomas T 2018. Challenging surgical dogma in the management of proximal esophageal atresia with distal tracheoesophageal fistula: Outcomes from the Midwest Pediatric Surgery Consortium. Journal of pediatric surgery, 53 7, 1267-1272Marchix, Justine; Goddard, Gillian; Helmrath, Michael A 2018. Host-Gut Microbiota Crosstalk in Intestinal Adaptation. Cellular and molecular gastroenterology and hepatology, 6 2, 149-162Michalsky, Marc P; Inge, Thomas H; Jenkins, Todd M; Xie, Changchun; Courcoulas, Anita; Helmrath, Michael; Brandt, Mary L; Harmon, Carroll M; Chen, Mike; Dixon, John B; Urbina, Elaine M 2018. Cardiovascular Risk Factors After Adolescent Bariatric Surgery. Pediatrics, 141 2, Minneci, Peter C; Kabre, Rashmi S; Mak, Grace Z; Halleran, Devin R; Cooper, Jennifer N; Afrazi, Amin; Calkins, Casey M; Downard, Cynthia D; Ehrlich, Peter; Fraser, Jason; Gadepalli, Samir K; Helmrath, Michael A; Kohler, Jonathan E; Landisch, Rachel; Landman, Matthew P; Lee, Constance; Leys, Charles M; Lodwick, Daniel L; Mon, Rodrigo; McClure, Beth; Rymeski, Beth; Saito, Jacqueline M; Sato, Thomas T; St Peter, Shawn D; Wood, Richard; Levitt, Marc A; Deans, Katherine J 2018. Screening practices and associated anomalies in infants with anorectal malformations: Results from the Midwest Pediatric Surgery Consortium. Journal of pediatric surgery, 53 6, 1163-1167Poling, Holly M; Wu, David; Brown, Nicole; Baker, Michael; Hausfeld, Taylor A; Huynh, Nhan; Chaffron, Samuel; Dunn, James C Y; Hogan, Simon P; Wells, James M; Helmrath, Michael A; Mahe, Maxime M 2018. Mechanically induced development and maturation of human intestinal organoids in vivo. Nature biomedical engineering, 2 6, 429-442Sinagoga, Katie L; McCauley, Heather A; Múnera, Jorge O; Reynolds, Nichole A; Enriquez, Jacob R; Watson, Carey; Yang, Hsiu-Chiung; Helmrath, Michael A; Wells, James M 2018. Deriving functional human enteroendocrine cells from pluripotent stem cells. Development (Cambridge, England), 145 19, Takebe, Takanori; Wells, James M; Helmrath, Michael A; Zorn, Aaron M 2018. Organoid Center Strategies for Accelerating Clinical Translation. Cell stem cell, 22 6, 806-809Asai, Akihiro; Aihara, Eitaro; Watson, Carey; Mourya, Reena; Mizuochi, Tatsuki; Shivakumar, Pranavkumar; Phelan, Kieran; Mayhew, Christopher; Helmrath, Michael; Takebe, Takanori; Wells, James; Bezerra, Jorge A 2017. Paracrine signals regulate human liver organoid maturation from induced pluripotent stem cells. Development (Cambridge, England), 144 6, 1056-1064Bertaux-Skeirik, Nina; Wunderlich, Mark; Teal, Emma; Chakrabarti, Jayati; Biesiada, Jacek; Mahe, Maxime; Sundaram, Nambirajan; Gabre, Joel; Hawkins, Jennifer; Gao, Jian; Engevik, Amy C; Yang, Li; Wang, Jiang; Goldenring, James R; Qualls, Joseph E; Medvedovic, Mario; Helmrath, Michael A; Diwan, Tayyab; Mulloy, James C; Zavros, Yana 2017. CD44 variant isoform 9 emerges in response to injury and contributes to the regeneration of the gastric epithelium. The Journal of pathology, , Inge, Thomas H; Jenkins, Todd M; Xanthakos, Stavra A; Dixon, John B; Daniels, Stephen R; Zeller, Meg H; Helmrath, Michael A 2017. Long-term outcomes of bariatric surgery in adolescents with severe obesity (FABS-5+): a prospective follow-up analysis. The lancet. Diabetes & endocrinology, 5 3, 165-173Mahe, Maxime M; Brown, Nicole E; Poling, Holly M; Helmrath, Michael A 2017. Erratum to: In Vivo Model of Small Intestine. Methods in molecular biology (Clifton, N.J.), 1597 , E1Maxime, Mahe M; Brown, Nicole E; Poling, Holly M; Michael, Helmrath A 2017. In Vivo Model of Small Intestine. Methods in molecular biology (Clifton, N.J.), 1597 , 229-245Múnera, Jorge O; Sundaram, Nambirajan; Rankin, Scott A; Hill, David; Watson, Carey; Mahe, Maxime; Vallance, Jefferson E; Shroyer, Noah F; Sinagoga, Katie L; Zarzoso-Lacoste, Adrian; Hudson, Jonathan R; Howell, Jonathan C; Chatuvedi, Praneet; Spence, Jason R; Shannon, John M; Zorn, Aaron M; Helmrath, Michael A; Wells, James M 2017. Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling. Cell stem cell, 21 1, 51-64.e6Nalapareddy, Kodandaramireddy; Nattamai, Kalpana J; Kumar, Rupali S; Karns, Rebekah; Wikenheiser-Brokamp, Kathryn A; Sampson, Leesa L; Mahe, Maxime M; Sundaram, Nambirajan; Yacyshyn, Mary-Beth; Yacyshyn, Bruce; Helmrath, Michael A; Zheng, Yi; Geiger, Hartmut 2017. Canonical Wnt Signaling Ameliorates Aging of Intestinal Stem Cells. Cell reports, 18 11, 2608-2621Sarwer, David B; Dilks, Rebecca J; Spitzer, Jacqueline C; Berkowitz, Robert I; Wadden, Thomas A; Moore, Renee H; Chittams, Jesse L; Brandt, Mary L; Chen, Mike K; Courcoulas, Anita P; Harmon, Carroll M; Helmrath, Michael A; Michalsky, Marc P; Xanthakos, Stavra A; Zeller, Meg H; Jenkins, Todd M; Inge, Thomas H 2017. Changes in Dietary Intake and Eating Behavior in Adolescents After Bariatric Surgery: an Ancillary Study to the Teen-LABS Consortium. Obesity surgery, 27 12, 3082-3091Wessel, Jacqueline; Kotagal, Meera; Helmrath, Michael A 2017. Management of Pediatric Intestinal Failure. Advances in pediatrics, 64 1, 253-267Workman, Michael J; Mahe, Maxime M; Trisno, Stephen; Poling, Holly M; Watson, Carey L; Sundaram, Nambirajan; Chang, Ching-Fang; Schiesser, Jacqueline; Aubert, Philippe; Stanley, Edouard G; Elefanty, Andrew G; Miyaoka, Yuichiro; Mandegar, Mohammad A; Conklin, Bruce R; Neunlist, Michel; Brugmann, Samantha A; Helmrath, Michael A; Wells, James M 2017. Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system. Nature medicine, 23 1, 49-59Zeller, Meg H; Pendery, Emma C; Reiter-Purtill, Jennifer; Hunsaker, Sanita L; Jenkins, Todd M; Helmrath, Michael A; Inge, Thomas H 2017. From adolescence to young adulthood: trajectories of psychosocial health following Roux-en-Y gastric bypass. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, , Cohran, Valeria; Managlia, Elizabeth; Bradford, Emily M; Goretsky, Tatiana; Li, Ting; Katzman, Rebecca B; Cheresh, Paul; Brown, Jeffrey B; Hawkins, Jennifer; Liu, Shirley X L; De Plaen, Isabelle G; Weitkamp, Jörn-Hendrik; Helmrath, Michael; Zhang, Zheng; Barrett, Terrence A 2016. Epithelial PIK3R1 (p85) and TP53 Regulate Survivin Expression during Adaptation to Ileocecal Resection. The American journal of pathology, 186 7, 1837-46Cushing, Christopher C; Martinez-Leo, Bruno; Bischoff, Andrea; Hall, Jennifer; Helmrath, Michael; Dickie, Belinda H; Levitt, Marc A; Peña, Alberto; Zeller, Meg H; Frischer, Jason S 2016. Health-Related Quality of Life and Parental Stress in Children With Fecal Incontinence: A Normative Comparison. Journal of pediatric gastroenterology and nutrition, 63 6, 633-636Engevik, Amy C; Feng, Rui; Choi, Eunyoung; White, Shana; Bertaux-Skeirik, Nina; Li, Jing; Mahe, Maxime M; Aihara, Eitaro; Yang, Li; DiPasquale, Betsy; Oh, Sunghee; Engevik, Kristen A; Giraud, Andrew S; Montrose, Marshall H; Medvedovic, Mario; Helmrath, Michael A; Goldenring, James R; Zavros, Yana 2016. The Development of Spasmolytic Polypeptide/TFF2-Expressing Metaplasia (SPEM) During Gastric Repair Is Absent in the Aged Stomach. Cellular and molecular gastroenterology and hepatology, 2 5, 605-624Hirschl, Ronald B; Minneci, Peter; Gadepalli, Samir; Saito, Jacqueline M; Askegard-Giesmann, Johanna; Deans, Katherine; Downard, Cynthia; Fallat, Mary; Finnell, Maria; Helmrath, Michael; Kabre, Rashmi; Lal, David; Leys, Charles; Mak, Grace; Ostlie, Daniel; Rescorla, Fred; Sato, Thomas; St Peter, Shawn; von Allmen, Daniel; Warner, Brad 2016. Development of a multi-institutional clinical research consortium for pediatric surgery. Journal of pediatric surgery, , Inge, Thomas H; Courcoulas, Anita P; Jenkins, Todd M; Michalsky, Marc P; Helmrath, Michael A; Brandt, Mary L; Harmon, Carroll M; Zeller, Meg H; Chen, Mike K; Xanthakos, Stavra A; Horlick, Mary; Buncher, C Ralph 2016. Weight Loss and Health Status 3 Years after Bariatric Surgery in Adolescents. The New England journal of medicine, 374 2, 113-23Lal, Dave R; Gadepalli, Samir K; Downard, Cynthia D; Ostlie, Daniel J; Minneci, Peter C; Swedler, Ruth M; Chelius, Thomas; Cassidy, Laura; Rapp, Cooper T; Deans, Katherine J; Fallat, Mary E; Finnell, S Maria E; Helmrath, Michael A; Hirschl, Ronald B; Kabre, Rashmi S; Leys, Charles M; Mak, Grace; Raque, Jessica; Rescorla, Frederick J; Saito, Jacqueline M; St Peter, Shawn D; von Allmen, Daniel; Warner, Brad W; Sato, Thomas T 2016. Perioperative management and outcomes of esophageal atresia and tracheoesophageal fistula. Journal of pediatric surgery, , Mezoff, Ethan A; Hawkins, Jennifer A; Ollberding, Nicholas J; Karns, Rebekah; Morrow, Ardythe L; Helmrath, Michael A 2016. The human milk oligosaccharide 2'-fucosyllactose augments the adaptive response to extensive intestinal. American journal of physiology. Gastrointestinal and liver physiology, 310 6, G427-38Aihara, Eitaro; Mahe, Maxime M; Schumacher, Michael A; Matthis, Andrea L; Feng, Rui; Ren, Wenwen; Noah, Taeko K; Matsu-ura, Toru; Moore, Sean R; Hong, Christian I; Zavros, Yana; Herness, Scott; Shroyer, Noah F; Iwatsuki, Ken; Jiang, Peihua; Helmrath, Michael A; Montrose, Marshall H 2015. Characterization of stem/progenitor cell cycle using murine circumvallate papilla taste bud organoid. Scientific reports, 5 , 17185Bout-Tabaku, Sharon; Michalsky, Marc P; Jenkins, Todd M; Baughcum, Amy; Zeller, Meg H; Brandt, Mary L; Courcoulas, Anita; Buncher, Ralph; Helmrath, Michael; Harmon, Carroll M; Chen, Mike K; Inge, Thomas H 2015. Musculoskeletal Pain, Self-reported Physical Function, and Quality of Life in the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) Cohort. JAMA pediatrics, 169 6, 552-9Michalsky, Marc P; Inge, Thomas H; Simmons, Mark; Jenkins, Todd M; Buncher, Ralph; Helmrath, Michael; Brandt, Mary L; Harmon, Carroll M; Courcoulas, Anita; Chen, Michael; Horlick, Mary; Daniels, Stephen R; Urbina, Elaine M 2015. Cardiovascular Risk Factors in Severely Obese Adolescents: The Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) Study. JAMA pediatrics, 169 5, 438-44Moon, Changsuk; Zhang, Weiqiang; Sundaram, Nambirajan; Yarlagadda, Sunitha; Reddy, Vadde Sudhakar; Arora, Kavisha; Helmrath, Michael A; Naren, Anjaparavanda P 2015. Drug-induced secretory diarrhea: A role for CFTR. Pharmacological research, 102 , 107-12Xanthakos, Stavra A; Jenkins, Todd M; Kleiner, David E; Boyce, Tawny W; Mourya, Reena; Karns, Rebekah; Brandt, Mary L; Harmon, Carroll M; Helmrath, Michael A; Michalsky, Marc P; Courcoulas, Anita P; Zeller, Meg H; Inge, Thomas H 2015. High Prevalence of Nonalcoholic Fatty Liver Disease in Adolescents Undergoing Bariatric Surgery. Gastroenterology, , Zeller, Meg H; Inge, Thomas H; Modi, Avani C; Jenkins, Todd M; Michalsky, Marc P; Helmrath, Michael; Courcoulas, Anita; Harmon, Carroll M; Rofey, Dana; Baughcum, Amy; Austin, Heather; Price, Karin; Xanthakos, Stavra A; Brandt, Mary L; Horlick, Mary; Buncher, Ralph 2015. Severe obesity and comorbid condition impact on the weight-related quality of life of the adolescent patient. The Journal of pediatrics, 166 3, 651-9.e4Inge, Thomas H; Boyce, Tawny W; Lee, Margaret; Kollar, Linda; Jenkins, Todd M; Brandt, Mary L; Helmrath, Michael; Xanthakos, Stavra A; Zeller, Meg H; Harmon, Carroll M; Courcoulas, Anita; Michalsky, Marc P 2014. Access to care for adolescents seeking weight loss surgery. Obesity (Silver Spring, Md.), 22 12, 2593-7Inge, Thomas H; Zeller, Meg H; Jenkins, Todd M; Helmrath, Michael; Brandt, Mary L; Michalsky, Marc P; Harmon, Carroll M; Courcoulas, Anita; Horlick, Mary; Xanthakos, Stavra A; Dolan, Larry; Mitsnefes, Mark; Barnett, Sean J; Buncher, Ralph 2014. Perioperative outcomes of adolescents undergoing bariatric surgery: the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study. JAMA pediatrics, 168 1, 47-53Michalsky, Marc P; Inge, Thomas H; Teich, Steven; Eneli, Ihuoma; Miller, Rosemary; Brandt, Mary L; Helmrath, Michael; Harmon, Carroll M; Zeller, Meg H; Jenkins, Todd M; Courcoulas, Anita; Buncher, Ralph C 2014. Adolescent bariatric surgery program characteristics: the Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study experience. Seminars in pediatric surgery, 23 1, 5-10Xiao, Nianzhou; Jenkins, Todd M; Nehus, Edward; Inge, Thomas H; Michalsky, Marc P; Harmon, Carroll M; Helmrath, Michael A; Brandt, Mary L; Courcoulas, Anita; Moxey-Mims, Marva; Mitsnefes, Mark M 2014. Kidney function in severely obese adolescents undergoing bariatric surgery. Obesity (Silver Spring, Md.), 22 11, 2319-25Eradi, Balgopal; Hamrick, Miller; Bischoff, Andrea; Frischer, Jason S; Helmrath, Michael; Hall, Jennifer; Peña, Alberto; Levitt, Marc A 2013. The role of a colon resection in combination with a Malone appendicostomy as part of a bowel management program for the treatment of fecal incontinence. Journal of pediatric surgery, 48 11, 2296-300Ubesie, Agozie C; Kocoshis, Samuel A; Mezoff, Adam G; Henderson, Carol J; Helmrath, Michael A; Cole, Conrad R 2013. Multiple micronutrient deficiencies among patients with intestinal failure during and after transition to enteral nutrition. The Journal of pediatrics, 163 6, 1692-6Dehmer, Jeffrey J; Fuller, Megan K; Helmrath, Michael A 2011. Management of pediatric intestinal failure. Advances in pediatrics, 58 1, 181-94Hamrick, Miller; Helmrath, Michael; Bischoff, Andrea; Eradi, Balgopal; Levitt, Marc; Peña, Alberto 2011. Letter to the Editor regarding comparison of anorectal angle and continence after Georgeson and Peña procedures for high/intermediate imperforate anus. Journal of pediatric surgery, 46 5, 1019-20; author replBrandt, Mary L; Harmon, Carroll M; Helmrath, Michael A; Inge, Thomas H; McKay, Siripoom V; Michalsky, Marc P 2010. Morbid obesity in pediatric diabetes mellitus: surgical options and outcomes. Nature reviews. Endocrinology, 6 11, 637-45Inge, Thomas; Helmrath, Michael; Vierra, Mark 2010. The Santoro III massive enterectomy: how can we justify the risks in obese adolescents? Obesity surgery, 20 12, 1718-9Garrison, Aaron P; Helmrath, Michael A; Dekaney, Christopher M 2009. Intestinal stem cells. Journal of pediatric gastroenterology and nutrition, 49 1, 2-7Inge, Thomas H; Miyano, Go; Bean, Judy; Helmrath, Michael; Courcoulas, Anita; Harmon, Carroll M; Chen, Mike K; Wilson, Kimberly; Daniels, Stephen R; Garcia, Victor F; Brandt, Mary L; Dolan, Lawrence M 2009. Reversal of type 2 diabetes mellitus and improvements in cardiovascular risk factors after surgical weight loss in adolescents. Pediatrics, 123 1, 214-22Inge, Thomas; Helmrath, Michael; Vierra, Mark; Ikramuddin, Sayeed 2008. Challenges of adolescent bariatric surgery: tips for managing the extremely obese teen. Journal of laparoendoscopic & advanced surgical techniques. Part A, 18 1, 157-69De Silva, Nirupama K; Helmrath, Michael A; Klish, William J 2007. Obesity in the adolescent female. Journal of pediatric and adolescent gynecology, 20 3, 207-13Fuller, Megan K; Helmrath, Michael A 2007. Thoracic empyema, application of video-assisted thoracic surgery and its current management. Current opinion in pediatrics, 19 3, 328-32Inge, Thomas H; Zeller, Meg; Harmon, Carroll; Helmrath, Michael; Bean, Judy; Modi, Avani; Horlick, Mary; Kalra, Maninder; Xanthakos, Stavra; Miller, Rosemary; Akers, Rachel; Courcoulas, Anita 2007. Teen-Longitudinal Assessment of Bariatric Surgery: methodological features of the first prospective multicenter study of adolescent bariatric surgery. Journal of pediatric surgery, 42 11, 1969-71Helmrath, Michael A; Brandt, Mary L; Inge, Thomas H 2006. Adolescent obesity and bariatric surgery. The Surgical clinics of North America, 86 2, 441-54, xKenton, Alexander B; Hegemier, Suzanne; Smith, E O'Brian; O'Donovan, Donough J; Brandt, Mary L; Cass, Darrell L; Helmrath, Michael A; Washburn, Kimberly; Weihe, Elizabeth K; Fernandes, Caraciolo J 2005. Platelet transfusions in infants with necrotizing enterocolitis do not lower mortality but may increase morbidity. Journal of perinatology : official journal of the California Perinatal Association, 25 3, 173-7Kenton, Alexander B; O'Donovan, Donough; Cass, Darrell L; Helmrath, Michael A; Smith, E O'brian; Fernandes, Caraciolo J; Washburn, Kimberly; Weihe, Elizabeth K; Brandt, Mary L 2005. Severe thrombocytopenia predicts outcome in neonates with necrotizing enterocolitis. Journal of perinatology : official journal of the California Perinatal Association, 25 1, 14-20Inge, Thomas H; Krebs, Nancy F; Garcia, Victor F; Skelton, Joseph A; Guice, Karen S; Strauss, Richard S; Albanese, Craig T; Brandt, Mary L; Hammer, Lawrence D; Harmon, Carol M; Kane, Timothy D; Klish, William J; Oldham, Keith T; Rudolph, Colin D; Helmrath, Michael A; Donovan, Edward; Daniels, Stephen R 2004. Bariatric surgery for severely overweight adolescents: concerns and recommendations. Pediatrics, 114 1, 217-23Klish, William J; Brandt, Mary L; Helmrath, Michael A 2004. Obesity surgery in pediatrics. Journal of pediatric gastroenterology and nutrition, 39 1, 2-4
Peer Reviewed Publications Bouffi, Carine; Wikenheiser-Brokamp, Kathryn A; Chaturvedi, Praneet; Sundaram, Nambirajan; Goddard, Gillian R; Wunderlich, Mark; Brown, Nicole E; Staab, Janet F; Latanich, Rachel; Zachos, Nicholas C; Holloway, Emily M; Mahe, Maxime M; Poling, Holly M; Vales, Simon; Fisher, Garrett W; Spence, Jason R; Mulloy, James C; Zorn, Aaron M; Wells, James M; Helmrath, Michael A 2023. In vivo development of immune tissue in human intestinal organoids transplanted into humanized mice. Nature biotechnology, 41 6, 824-831Gil, Lindsay A; Lutz, Carley M; Dillon, Patrick A; Downard, Cynthia D; Ehrlich, Peter F; Fallat, Mary E; Fraser, Jason D; Grabowski, Julia E; Helmrath, Michael A; Hertweck, S Paige; Hirschl, Ronald B; Kabre, Rashmi; Lal, Dave R; Landman, Matthew P; Lawrence, Amy E; Leys, Charles M; Mak, Grace Z; Markel, Troy A; Raiji, Manish T; Rymeski, Beth; Saito, Jacqueline M; Sato, Thomas T; St Peter, Shawn D; Stafford, Linda M Cherney; Deans, Katherine J; Minneci, Peter C; Hewitt, Geri D; Aldrink, Jennifer H 2023. Use and Accuracy of Intraoperative Frozen Section Analysis for Ovarian Masses in Children and Adolescents. Journal of pediatric and adolescent gynecology, 36 2, 155-159Marquart, John P; Bowder, Alexis N; Bence, Christina M; St Peter, Shawn D; Gadepalli, Samir K; Sato, Thomas T; Szabo, Aniko; Minneci, Peter C; Hirschl, Ronald B; Rymeski, Beth A; Downard, Cynthia D; Markel, Troy A; Deans, Katherine J; Fallat, Mary E; Fraser, Jason D; Grabowski, Julia E; Helmrath, Michael A; Kabre, Rashmi D; Kohler, Jonathan E; Landman, Matthew P; Lawrence, Amy E; Leys, Charles M; Mak, Grace Z; Port, Elissa; Saito, Jacqueline; Silverberg, Jared; Slidell, Mark B; Wright, Tiffany N; Lal, Dave R 2023. Thoracoscopy versus thoracotomy for esophageal atresia and tracheoesophageal fistula: Outcomes from the Midwest Pediatric Surgery Consortium. Journal of pediatric surgery, 58 1, 27-33Moran-Lev, Hadar; Kocoshis, Samuel A; Oliveira, Stephanie B; Helmrath, Michael; Cole, Conrad R 2023. Chronic Mucosal Inflammation in Pediatric Intestinal Failure Patients- a Unique Phenomenon. Journal of pediatric gastroenterology and nutrition, , O'Connell, Amy E; Raveenthiraraj, Sathuwarman; Adegboye, Comfort; Qi, Wanshu; Khetani, Radhika S; Singh, Akaljot; Sundaram, Nambirajam; Emeonye, Chidera; Lin, Jasmine; Goldsmith, Jeffrey D; Thiagarajah, Jay R; Carlone, Diana L; Turner, Jerrold R; Agrawal, Pankaj B; Helmrath, Michael; Breault, David T 2023. WNT2B Deficiency Causes Increased Susceptibility to Colitis in Mice and Impairs Intestinal Epithelial Development in Humans. bioRxiv : the preprint server for biology, , Singh, Akaljot; Poling, Holly M; Chaturvedi, Praneet; Thorner, Konrad; Sundaram, Nambirajan; Kechele, Daniel O; Childs, Charlie J; McCauley, Heather A; Fisher, Garrett W; Brown, Nicole E; Spence, Jason R; Wells, James M; Helmrath, Michael A 2023. Transplanted human intestinal organoids: a resource for modeling human intestinal development. Development (Cambridge, England), 150 9, Zeller, Meg H; Strong, Heather; Reiter-Purtill, Jennifer; Jenkins, Todd M; Mitchell, James E; Michalsky, Marc P; Helmrath, Michael A 2023. Marijuana, e-cigarette, and tobacco product use in young adults who underwent pediatric bariatric surgery. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 19 5, 512-521Bowder, Alexis N; Bence, Christina M; Rymeski, Beth A; Gadepalli, Samir K; Sato, Thomas T; Szabo, Aniko; Arendonk, Kyle Van; Minneci, Peter C; Downard, Cynthia D; Hirschl, Ronald B; Markel, Troy; Courtney, Cathleen M; Deans, Katherine J; Fallat, Mary E; Fraser, Jason D; Grabowski, Julia E; Helmrath, Michael A; Kabre, Rashmi D; Kohler, Jonathan E; Landman, Matthew P; Lawrence, Amy E; Leys, Charles M; Mak, Grace; Port, Elissa; Saito, Jacqueline; Silverberg, Jared; Slidell, Mark B; St Peter, Shawn D; Troutt, Misty; Wright, Tiffany N; Lal, Dave R 2022. Acid suppression duration does not alter anastomotic stricture rates after esophageal atresia with distal tracheoesophageal fistula repair: A prospective multi-institutional cohort study. Journal of pediatric surgery, 57 6, 975-980Capeling, Meghan M; Huang, Sha; Childs, Charlie J; Wu, Joshua H; Tsai, Yu-Hwai; Wu, Angeline; Garg, Neil; Holloway, Emily M; Sundaram, Nambirajan; Bouffi, Carine; Helmrath, Michael; Spence, Jason R 2022. Suspension culture promotes serosal mesothelial development in human intestinal organoids. Cell reports, 38 7, 110379Chakrabarti, Jayati; Dua-Awereh, Martha; Schumacher, Michael; Engevik, Amy; Hawkins, Jennifer; Helmrath, Michael A; Zavros, Yana 2022. Sonic Hedgehog acts as a macrophage chemoattractant during regeneration of the gastric epithelium. NPJ Regenerative medicine, 7 1, 3Decker, Kristina M; Reiter-Purtill, Jennifer; Bejarano, Carolina M; Goldschmidt, Andrea B; Mitchell, James E; Jenkins, Todd M; Helmrath, Michael; Inge, Thomas H; Michalsky, Marc P; Zeller, Meg H 2022. Psychosocial predictors of problematic eating in young adults who underwent adolescent bariatric surgery. Obesity science & practice, 8 5, 545-555Dekonenko, Charlene; Fraser, Jason D; Deans, Katherine; Fallat, Mary E; Helmrath, Michael; Kabre, Rashmi; Leys, Charles M; Burns, R Cartland; Corkum, Kristine; Dillon, Patrick A; Downard, Cynthia; Wright, Tiffany N; Gadepalli, Samir K; Grabowski, Julia; Hernandez, Edward; Hirschl, Ronald; Johnson, Kevin N; Kohler, Jonathan; Landman, Matthew P; Landisch, Rachel M; Lawrence, Amy E; Mak, Grace Z; Minneci, Peter; Rymeski, Beth; Sato, Thomas T; Slater, Bethany J; Peter, St Shawn D 2022. Does Use of a Feeding Protocol Change Outcomes in Gastroschisis? A Report from the Midwest Pediatric Surgery Consortium. European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 32 2, 153-159Ding, Lin; Chakrabarti, Jayati; Sheriff, Sulaiman; Li, Qian; Thi Hong, Hahn Nguyen; Sontz, Ricky A; Mendoza, Zoe E; Schreibeis, Amanda; Helmrath, Michael A; Zavros, Yana; Merchant, Juanita L 2022. Toll-like Receptor 9 Pathway Mediates Schlafen+-MDSC Polarization During Helicobacter-induced Gastric Metaplasias. Gastroenterology, 163 2, 411-425.e4Eicher, Alexandra K; Kechele, Daniel O; Sundaram, Nambirajan; Berns, H Matthew; Poling, Holly M; Haines, Lauren E; Sanchez, J Guillermo; Kishimoto, Keishi; Krishnamurthy, Mansa; Han, Lu; Zorn, Aaron M; Helmrath, Michael A; Wells, James M 2022. Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells. Cell stem cell, 29 1, 36-51.e6Engwall-Gill, Abigail J; Chan, Sherwin S; Boyd, Kevin P; Saito, Jacqueline M; Fallat, Mary E; St Peter, Shawn D; Bolger-Theut, Stephanie; Crotty, Eric J; Green, Jared R; Hulett Bowling, Rebecca L; Kumbhar, Sachin S; Rattan, Mantosh S; Young, Cody M; Canner, Joseph K; Deans, Katherine J; Gadepalli, Samir K; Helmrath, Michael A; Hirschl, Ronald B; Kabre, Rashmi; Lal, Dave R; Landman, Matthew P; Leys, Charles M; Mak, Grace Z; Minneci, Peter C; Wright, Tiffany N; Kunisaki, Shaun M 2022. Accuracy of Chest Computed Tomography in Distinguishing Cystic Pleuropulmonary Blastoma From Benign Congenital Lung Malformations in Children. JAMA network open, 5 6, e2219814Fraser, James A; Deans, Katherine J; Fallat, Mary E; Helmrath, Michael; Kabre, Rashmi; Leys, Charles M; Markel, Troy A; Dillon, Patrick A; Downard, Cynthia; Wright, Tiffany N; Gadepalli, Samir K; Grabowski, Julia E; Hirschl, Ronald; Johnson, Kevin N; Kohler, Jonathan E; Landman, Matthew P; Mak, Grace Z; Minneci, Peter C; Rymeski, Beth; Sato, Thomas T; Slater, Bethany J; Peter, Shawn D St; Fraser, Jason D 2022. Evaluating the risk of peri-umbilical hernia after sutured or sutureless gastroschisis closure. Journal of pediatric surgery, 57 12, 786-791Kunisaki, Shaun M; Saito, Jacqueline M; Fallat, Mary E; Peter, Shawn D St; Lal, Dave R; Karmakar, Monita; Deans, Katherine J; Gadepalli, Samir K; Hirschl, Ronald B; Minneci, Peter C; Helmrath, Michael A 2022. Fetal Risk Stratification and Outcomes in Children with Prenatally Diagnosed Lung Malformations: Results from a Multi-Institutional Research Collaborative. Annals of surgery, 276 5, e622-e630McNelis, Kera; Poindexter, Anne; Goddard, Gillian; Riddle, Stefanie; Wessel, Jacqueline; Helmrath, Michael 2022. Body Composition of Infants With Congenital Gastroschisis. Journal of pediatric gastroenterology and nutrition, 74 2, e35-e38Minneci, Peter C; Hade, Erinn M; Gil, Lindsay A; Metzger, Gregory A; Saito, Jacqueline M; Mak, Grace Z; Hirschl, Ronald B; Gadepalli, Samir; Helmrath, Michael A; Leys, Charles M; Sato, Thomas T; Lal, Dave R; Landman, Matthew P; Kabre, Rashmi; Fallat, Mary E; Cooper, Jennifer N; Deans, Katherine J 2022. Demographic and Clinical Characteristics Associated With the Failure of Nonoperative Management of Uncomplicated Appendicitis in Children: Secondary Analysis of a Nonrandomized Clinical Trial. JAMA network open, 5 5, e229712Pitstick, Amy L; Poling, Holly M; Sundaram, Nambirajan; Lewis, Phillip L; Kechele, Daniel O; Sanchez, J Guillermo; Scott, Melissa A; Broda, Taylor R; Helmrath, Michael A; Wells, James M; Mayhew, Christopher N 2022. Aggregation of cryopreserved mid-hindgut endoderm for more reliable and reproducible hPSC-derived small intestinal organoid generation. Stem cell reports, 17 8, 1889-1902Rosselot, Andrew E; Park, Miri; Kim, Mari; Matsu-Ura, Toru; Wu, Gang; Flores, Danilo E; Subramanian, Krithika R; Lee, Suengwon; Sundaram, Nambirajan; Broda, Taylor R; McCauley, Heather A; Hawkins, Jennifer A; Chetal, Kashish; Salomonis, Nathan; Shroyer, Noah F; Helmrath, Michael A; Wells, James M; Hogenesch, John B; Moore, Sean R; Hong, Christian I 2022. Ontogeny and function of the circadian clock in intestinal organoids. The EMBO journal, 41 2, e106973Arora, Kavisha; Yang, Fanmuyi; Brewington, John; McPhail, Gary; Cortez, Alexander R; Sundaram, Nambirajan; Ramananda, Yashaswini; Ogden, Herbert; Helmrath, Michael; Clancy, John P; Naren, Anjaparavanda P 2021. Patient personalized translational tools in cystic fibrosis to transform data from bench to bed-side and back. American journal of physiology. Gastrointestinal and liver physiology, 320 6, G1123-G1130Bence, Christina M; Rymeski, Beth; Gadepalli, Samir; Sato, Thomas T; Minneci, Peter C; Downard, Cynthia; Hirschl, Ronald B; Amin, Ruchi A; Burns, R Cartland; Cherney-Stafford, Linda; Courtney, Cathleen M; Deans, Katherine J; Fallat, Mary E; Fraser, Jason D; Grabowski, Julia E; Helmrath, Michael A; Kabre, Rashmi D; Kohler, Jonathan E; Landman, Matthew P; Lawrence, Amy E; Leys, Charles M; Mak, Grace Z; Port, Elissa; Saito, Jacqueline M; Silverberg, Jared; Slidell, Mark B; St Peter, Shawn D; Troutt, Misty; Walker, Sarah; Wright, Tiffany; Lal, Dave R 2021. Clinical outcomes following implementation of a management bundle for esophageal atresia with distal tracheoesophageal fistula. Journal of pediatric surgery, 56 1, 47-54Chakrabarti, Jayati; Koh, Vivien; Steele, Nina; Hawkins, Jennifer; Ito, Yoshiaki; Merchant, Juanita L; Wang, Jiang; Helmrath, Michael A; Ahmad, Syed A; So, Jimmy Bok Yan; Yong, Wei Peng; Zavros, Yana 2021. Disruption of Her2-Induced PD-L1 Inhibits Tumor Cell Immune Evasion in Patient-Derived Gastric Cancer Organoids. Cancers, 13 24, Chan, Calvin C; Harley, Isaac T W; Pfluger, Paul T; Trompette, Aurelien; Stankiewicz, Traci E; Allen, Jessica L; Moreno-Fernandez, Maria E; Damen, Michelle S M A; Oates, Jarren R; Alarcon, Pablo C; Doll, Jessica R; Flick, Matthew J; Flick, Leah M; Sanchez-Gurmaches, Joan; Mukherjee, Rajib; Karns, Rebekah; Helmrath, Michael; Inge, Thomas H; Weisberg, Stuart P; Pamp, Sünje J; Relman, David A; Seeley, Randy J; Tschöp, Matthias H; Karp, Christopher L; Divanovic, Senad 2021. A BAFF/APRIL axis regulates obesogenic diet-driven weight gain. Nature communications, 12 1, 2911Criss, Zachary K; Bhasin, Nobel; Di Rienzi, Sara C; Rajan, Anubama; Deans-Fielder, Kali; Swaminathan, Ganesh; Kamyabi, Nabiollah; Zeng, Xi-Lei; Doddapaneni, Harsha; Menon, Vipin K; Chakravarti, Deepavali; Estrella, Clarissa; Yu, Xiaomin; Patil, Ketki; Petrosino, Joseph F; Fleet, James C; Verzi, Michael P; Christakos, Sylvia; Helmrath, Michael A; Arimura, Sumimasa; DePinho, Ronald A; Britton, Robert A; Maresso, Anthony W; Grande-Allen, K Jane; Blutt, Sarah E; Crawford, Sue E; Estes, Mary K; Ramani, Sasirekha; Shroyer, Noah F 2021. Drivers of transcriptional variance in human intestinal epithelial organoids. Physiological genomics, 53 11, 486-508Dekonenko, Charlene; Fraser, Jason D; Deans, Katherine J; Fallat, Mary E; Helmrath, Michael; Kabre, Rashmi; Leys, Charles M; Burns, R Cartland; Corkumd, Kristine; Dillon, Patrick A; Downard, Cynthia; Wright, Tiffany N; Gadepalli, Samir K; Grabowski, Julia E; Hernandez, Edward; Hirschl, Ronald; Johnson, Kevin N; Kohler, Jonathan E; Landman, Matthew P; Landisch, Rachel M; Lawrence, Amy E; Mak, Grace Z; Minneci, Peter C; Rymeski, Beth; Sato, Thomas T; Slater, Bethany J; St Peter, Shawn D 2021. Outcomes in gastroschisis: expectations in the postnatal period for simple vs complex gastroschisis. Journal of perinatology : official journal of the California Perinatal Association, 41 7, 1755-1759Goddard, Gillian R; McNelis, Kera; Poindexter, Anne; Jenkins, Todd; Wessel, Jacqueline; Nathan, Amy T; Helmrath, Michael A; Poindexter, Brenda 2021. Quality Improvement Efforts Reduce Incidence of Surgical Necrotizing Enterocolitis and Related Deaths. American journal of perinatology, 38 13, 1386-1392Kasendra, Magdalena; Troutt, Misty; Broda, Taylor; Bacon, W Clark; Wang, Timothy C; Niland, Joyce C; Helmrath, Michael A 2021. Intestinal organoids: roadmap to the clinic. American journal of physiology. Gastrointestinal and liver physiology, 321 1, G1-G10Koh, Vivien; Chakrabarti, Jayati; Torvund, Meaghan; Steele, Nina; Hawkins, Jennifer A; Ito, Yoshiaki; Wang, Jiang; Helmrath, Michael A; Merchant, Juanita L; Ahmed, Syed A; Shabbir, Asim; Yan So, Jimmy Bok; Yong, Wei Peng; Zavros, Yana 2021. Hedgehog transcriptional effector GLI mediates mTOR-Induced PD-L1 expression in gastric cancer organoids. Cancer letters, 518 , 59-71Kunisaki, Shaun M; Lal, Dave R; Saito, Jacqueline M; Fallat, Mary E; St Peter, Shawn D; Fox, Zachary D; Heider, Amer; Chan, Sherwin S; Boyd, Kevin P; Burns, R Cartland; Deans, Katherine J; Gadepalli, Samir K; Hirschl, Ronald B; Kabre, Rashmi; Landman, Matthew P; Leys, Charles M; Mak, Grace Z; Minneci, Peter C; Wright, Tiffany N; Helmrath, Michael A 2021. Pleuropulmonary Blastoma in Pediatric Lung Lesions. Pediatrics, 147 4, Lim, Irene Isabel P; Cushing, Christopher C; Jenkins, Todd; Troutt, Misty; Zeller, Margaret H; Hossain, Monir; Rymeski, Beth; Helmrath, Michael; Frischer, Jason S 2021. Prospective quality of life outcomes in pediatric fecal incontinence following bowel management. Journal of pediatric surgery, 56 8, 1459-1464McNelis, Kera; Goddard, Gillian; Jenkins, Todd; Poindexter, Anne; Wessel, Jacqueline; Helmrath, Michael; Poindexter, Brenda 2021. Delay in achieving enteral autonomy and growth outcomes in very low birth weight infants with surgical necrotizing enterocolitis. Journal of perinatology : official journal of the California Perinatal Association, 41 1, 150-156Moreno-Fernandez, Maria E; Giles, Daniel A; Oates, Jarren R; Chan, Calvin C; Damen, Michelle S M A; Doll, Jessica R; Stankiewicz, Traci E; Chen, Xiaoting; Chetal, Kashish; Karns, Rebekah; Weirauch, Matthew T; Romick-Rosendale, Lindsey; Xanthakos, Stavra A; Sheridan, Rachel; Szabo, Sara; Shah, Amy S; Helmrath, Michael A; Inge, Thomas H; Deshmukh, Hitesh; Salomonis, Nathan; Divanovic, Senad 2021. PKM2-dependent metabolic skewing of hepatic Th17 cells regulates pathogenesis of non-alcoholic fatty liver disease. Cell metabolism, 33 6, 1187-1204.e9Shah, Amy S; Helmrath, Michael A; Inge, Thomas H; Xanthakos, Stavra A; Kelsey, Megan M; Jenkins, Todd; Trout, Andrew T; Browne, Lorna; Nadeau, Kristen J 2021. Study protocol: a prospective controlled clinical trial to assess surgical or medical treatment for paediatric type 2 diabetes (ST2OMP). BMJ open, 11 8, e047766Weller, Jennine H; Peter, Shawn D St; Fallat, Mary E; Saito, Jacqueline M; Burns, Cartland R; Deans, Katherine J; Fraser, Jason D; Gadepalli, Samir K; Helmrath, Michael A; Hirschl, Ronald B; Kabre, Rashmi; Lal, Dave R; Landman, Matthew P; Leys, Charles M; Mak, Grace Z; Minneci, Peter C; Wright, Tiffany N; Kunisaki, Shaun M 2021. Thoracoscopic versus open lobectomy in infants with congenital lung malformations: A multi-institutional propensity score analysis. Journal of pediatric surgery, 56 12, 2148-2156Chan, Calvin C; Damen, Michelle S M A; Moreno-Fernandez, Maria E; Stankiewicz, Traci E; Cappelletti, Monica; Alarcon, Pablo C; Oates, Jarren R; Doll, Jessica R; Mukherjee, Rajib; Chen, Xiaoting; Karns, Rebekah; Weirauch, Matthew T; Helmrath, Michael A; Inge, Thomas H; Divanovic, Senad 2020. Type I interferon sensing unlocks dormant adipocyte inflammatory potential. Nature communications, 11 1, 2745Dewberry, Lindel C; Jalivand, Anahita; Gupta, Resmi; Jenkins, Todd M; Beamish, Andrew; Inge, Thomas H; Courcoulas, Anita; Helmrath, Michael; Brandt, Mary L; Harmon, Carroll M; Chen, Mike; Dixon, John B; Zeller, Margaret; Michalsky, Marc P 2020. Weight Loss and Health Status 5 Years After Adjustable Gastric Banding in Adolescents. Obesity surgery, 30 6, 2388-2394Fraser, Jason D; Deans, Katherine J; Fallat, Mary E; Helmrath, Michael A; Kabre, Rashmi; Leys, Charles M; Burns, R Cartland; Corkum, Kristine; Dillon, Patrick A; Downard, Cynthia D; Gadepalli, Samir K; Grabowski, Julia E; Hernandez, Edward; Hirschl, Ronald B; Johnson, Kevin N; Kohler, Jonathan E; Landman, Matthew P; Landisch, Rachel M; Lawrence, Amy E; Mak, Grace Z; Minneci, Peter C; Rymeski, Beth; Sato, Thomas T; Scannell, Madeline; Slater, Bethany J; Wilkinson, Kathryn H; Wright, Tiffany N; St Peter, Shawn D 2020. Sutureless vs sutured abdominal wall closure for gastroschisis: Operative characteristics and early outcomes from the Midwest Pediatric Surgery Consortium. Journal of pediatric surgery, 55 11, 2284-2288Kunisaki, Shaun M; Saito, Jacqueline M; Fallat, Mary E; St Peter, Shawn D; Lal, Dave R; Johnson, Kevin N; Mon, Rodrigo A; Adams, Cheryl; Aladegbami, Bola; Bence, Christina; Burns, R Cartland; Corkum, Kristine S; Deans, Katherine J; Downard, Cynthia D; Fraser, Jason D; Gadepalli, Samir K; Helmrath, Michael A; Kabre, Rashmi; Landman, Matthew P; Leys, Charles M; Linden, Allison F; Lopez, Joseph J; Mak, Grace Z; Minneci, Peter C; Rademacher, Brooks L; Shaaban, Aimen; Walker, Sarah K; Wright, Tiffany N; Hirschl, Ronald B 2020. Development of a multi-institutional registry for children with operative congenital lung malformations. Journal of pediatric surgery, 55 7, 1313-1318Lamoshi, Abdulrouf; Chernoguz, Artur; Harmon, Carroll M; Helmrath, Michael 2020. Complications of bariatric surgery in adolescents. Seminars in pediatric surgery, 29 1, 150888Leys, Charles M; Hirschl, Ronald B; Kohler, Jonathan E; Cherney-Stafford, Linda; Marka, Nicholas; Fallat, Mary E; Gadepalli, Samir K; Fraser, Jason D; Grabowski, Julia; Burns, R Cartland; Downard, Cynthia D; Foley, David S; Halleran, Devin R; Helmrath, Michael A; Kabre, Rashmi; Knezevich, Michelle S; Lal, Dave R; Landman, Matthew P; Lawrence, Amy E; Mak, Grace Z; Minneci, Peter C; Musili, Ninette; Rymeski, Beth; Saito, Jacqueline M; Sato, Thomas T; St Peter, Shawn D; Warner, Brad W; Ostlie, Daniel J 2020. Changing the Paradigm for Management of Pediatric Primary Spontaneous Pneumothorax: A Simple Aspiration Test Predicts Need for Operation. Journal of pediatric surgery, 55 1, 169-175McCauley, Heather A; Matthis, Andrea L; Enriquez, Jacob R; Nichol, Jonah T; Sanchez, J Guillermo; Stone, William J; Sundaram, Nambirajan; Helmrath, Michael A; Montrose, Marshall H; Aihara, Eitaro; Wells, James M 2020. Enteroendocrine cells couple nutrient sensing to nutrient absorption by regulating ion transport. Nature communications, 11 1, 4791Minneci, Peter C; Hade, Erinn M; Lawrence, Amy E; Sebastião, Yuri V; Saito, Jacqueline M; Mak, Grace Z; Fox, Christa; Hirschl, Ronald B; Gadepalli, Samir; Helmrath, Michael A; Kohler, Jonathan E; Leys, Charles M; Sato, Thomas T; Lal, Dave R; Landman, Matthew P; Kabre, Rashmi; Fallat, Mary E; Cooper, Jennifer N; Deans, Katherine J 2020. Association of Nonoperative Management Using Antibiotic Therapy vs Laparoscopic Appendectomy With Treatment Success and Disability Days in Children With Uncomplicated Appendicitis. JAMA, 324 6, 581-593Pradhan, Suman; Karve, Sayali S; Weiss, Alison A; Hawkins, Jennifer; Poling, Holly M; Helmrath, Michael A; Wells, James M; McCauley, Heather A 2020. Tissue Responses to Shiga Toxin in Human Intestinal Organoids. Cellular and molecular gastroenterology and hepatology, 10 1, 171-190Shah, Amy S; Nadeau, Kristen J; Helmrath, Michael A; Inge, Thomas H; Xanthakos, Stavra A; Kelsey, Megan M 2020. Metabolic outcomes of surgery in youth with type 2 diabetes. Seminars in pediatric surgery, 29 1, 150893Singh, Akaljot; Poling, Holly M; Spence, Jason R; Wells, James M; Helmrath, Michael A 2020. Gastrointestinal organoids: a next-generation tool for modeling human development. American journal of physiology. Gastrointestinal and liver physiology, 319 3, G375-G381Singh, Akaljot; Poling, Holly M; Sundaram, Nambirajan; Brown, Nicole; Wells, James M; Helmrath, Michael A 2020. Evaluation of transplantation sites for human intestinal organoids. PloS one, 15 8, e0237885Sitzman, Thomas J; Carle, Adam C; Lundberg, Jaclyn N; Heaton, Pamela C; Helmrath, Michael A; Trotman, Carroll-Ann; Britto, Maria T 2020. Marked Variation Exists Among Surgeons and Hospitals in the Use of Secondary Cleft Lip Surgery. The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 57 2, 198-207Vales, Simon; Poling, Holly M; Sundaram, Nambirajan; Helmrath, Michael A; Mahe, Maxime M 2020. In Vivo Human PSC-Derived Intestinal Organoids to Study Stem Cell Maintenance. Methods in molecular biology (Clifton, N.J.), 2171 , 201-214Valvi, Damaskini; Walker, Douglas I; Inge, Thomas; Bartell, Scott M; Jenkins, Todd; Helmrath, Michael; Ziegler, Thomas R; La Merrill, Michele A; Eckel, Sandrah P; Conti, David; Liang, Yongliang; Jones, Dean P; McConnell, Rob; Chatzi, Leda 2020. Environmental chemical burden in metabolic tissues and systemic biological pathways in adolescent bariatric surgery patients: A pilot untargeted metabolomic approach. Environment international, 143 , 105957Xanthakos, Stavra A; Khoury, Jane C; Inge, Thomas H; Jenkins, Todd M; Modi, Avani C; Michalsky, Marc P; Chen, Mike K; Courcoulas, Anita P; Harmon, Carroll M; Brandt, Mary L; Helmrath, Michael A; Kalkwarf, Heidi J 2020. Nutritional Risks in Adolescents After Bariatric Surgery. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 18 5, 1070-1081.e5Bout-Tabaku, Sharon; Gupta, Resmi; Jenkins, Todd M; Ryder, Justin R; Baughcum, Amy E; Jackson, Rebecca D; Inge, Thomas H; Dixon, John B; Helmrath, Michael A; Courcoulas, Anita P; Mitchell, James E; Harmon, Carroll M; Xie, Changchun; Michalsky, Marc P 2019. Musculoskeletal Pain, Physical Function, and Quality of Life After Bariatric Surgery. Pediatrics, 144 6, Capeling, Meghan M; Czerwinski, Michael; Huang, Sha; Tsai, Yu-Hwai; Wu, Angeline; Nagy, Melinda S; Juliar, Benjamin; Sundaram, Nambirajan; Song, Yang; Han, Woojin M; Takayama, Shuichi; Alsberg, Eben; Garcia, Andres J; Helmrath, Michael; Putnam, Andrew J; Spence, Jason R 2019. Nonadhesive Alginate Hydrogels Support Growth of Pluripotent Stem Cell-Derived Intestinal Organoids. Stem cell reports, 12 2, 381-394Capurro, Mariana I; Greenfield, Laura K; Prashar, Akriti; Xia, Sunny; Abdullah, Majd; Wong, Harikesh; Zhong, Xi Zoe; Bertaux-Skeirik, Nina; Chakrabarti, Jayati; Siddiqui, Iram; O'Brien, Catherine; Dong, Xianping; Robinson, Lisa; Peek, Richard M; Philpott, Dana J; Zavros, Yana; Helmrath, Michael; Jones, Nicola L 2019. VacA generates a protective intracellular reservoir for Helicobacter pylori that is eliminated by activation of the lysosomal calcium channel TRPML1. Nature microbiology, 4 8, 1411-1423Goddard, Gillian R; Kotagal, Meera; Jenkins, Todd M; Kollar, Linda M; Inge, Thomas H; Helmrath, Michael A 2019. Weight loss after sleeve gastrectomy in developmentally delayed adolescents and young adults. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 15 10, 1662-1667Holokai, Loryn; Chakrabarti, Jayati; Broda, Taylor; Chang, Julie; Hawkins, Jennifer A; Sundaram, Nambirajan; Wroblewski, Lydia E; Peek, Richard M; Wang, Jiang; Helmrath, Michael; Wells, James M; Zavros, Yana 2019. Increased Programmed Death-Ligand 1 is an Early Epithelial Cell Response to Helicobacter pylori Infection. PLoS pathogens, 15 1, e1007468Inge, Thomas H; Courcoulas, Anita P; Helmrath, Michael A 2019. Five-Year Outcomes of Gastric Bypass in Adolescents as Compared with Adults. Reply. The New England journal of medicine, 381 9, e17Inge, Thomas H; Courcoulas, Anita P; Jenkins, Todd M; Michalsky, Marc P; Brandt, Mary L; Xanthakos, Stavra A; Dixon, John B; Harmon, Carroll M; Chen, Mike K; Xie, Changchun; Evans, Mary E; Helmrath, Michael A 2019. Five-Year Outcomes of Gastric Bypass in Adolescents as Compared with Adults. The New England journal of medicine, 380 22, 2136-2145Kunisaki, Shaun M; Saito, Jacqueline M; Fallat, Mary E; St Peter, Shawn D; Kim, Aimee G; Johnson, Kevin N; Mon, Rodrigo A; Adams, Cheryl; Aladegbami, Bola; Bence, Christina; Burns, R Cartland; Corkum, Kristine S; Deans, Katherine J; Downard, Cynthia D; Fraser, Jason D; Gadepalli, Samir K; Helmrath, Michael A; Kabre, Rashmi; Lal, Dave R; Landman, Matthew P; Leys, Charles M; Linden, Allison F; Lopez, Joseph J; Mak, Grace Z; Minneci, Peter C; Rademacher, Brooks L; Shaaban, Aimen; Walker, Sarah K; Wright, Tiffany N; Hirschl, Ronald B 2019. Current operative management of congenital lobar emphysema in children: A report from the Midwest Pediatric Surgery Consortium. Journal of pediatric surgery, 54 6, 1138-1142Lal, Dave R; Gadepalli, Samir K; Downard, Cynthia D; Minneci, Peter C; Knezevich, Michelle; Chelius, Thomas H; Rapp, Cooper T; Billmire, Deborah; Bruch, Steven; Carland Burns, R; Deans, Katherine J; Fallat, Mary E; Fraser, Jason D; Grabowski, Julia; Hebel, Ferdynand; Helmrath, Michael A; Hirschl, Ronald B; Kabre, Rashmi; Kohler, Jonathan; Landman, Matthew P; Leys, Charles M; Mak, Grace Z; Ostlie, Daniel J; Raque, Jessica; Rymeski, Beth; Saito, Jacqueline M; St Peter, Shawn D; von Allmen, Daniel; Warner, Brad W; Sato, Thomas T 2019. Infants with esophageal atresia and right aortic arch: Characteristics and outcomes from the Midwest Pediatric Surgery Consortium. Journal of pediatric surgery, 54 4, 688-692Minneci, Peter C; Hade, Erinn M; Lawrence, Amy E; Saito, Jacqueline M; Mak, Grace Z; Hirschl, Ronald B; Gadepalli, Samir; Helmrath, Michael A; Leys, Charles M; Sato, Thomas T; Lal, Dave R; Landman, Matthew P; Kabre, Rashmi; Fallat, Mary E; Fischer, Beth A; Cooper, Jennifer N; Deans, Katherine J 2019. Multi-institutional trial of non-operative management and surgery for uncomplicated appendicitis in children: Design and rationale. Contemporary clinical trials, 83 , 10-17Minneci, Peter C; Kabre, Rashmi S; Mak, Grace Z; Halleran, Devin R; Cooper, Jennifer N; Afrazi, Amin; Calkins, Casey M; Corkum, Kristine; Downard, Cynthia D; Ehrlich, Peter; Fraser, Jason D; Gadepalli, Samir K; Helmrath, Michael A; Kohler, Jonathan E; Landisch, Rachel; Landman, Matthew P; Lee, Constance; Leys, Charles M; Lodwick, Daniel L; McLeod, Jennifer; Mon, Rodrigo; McClure, Beth; Rymeski, Beth; Saito, Jacqueline M; Sato, Thomas T; St Peter, Shawn D; Wood, Richard; Levitt, Marc A; Deans, Katherine J 2019. Can fecal continence be predicted in patients born with anorectal malformations? Journal of pediatric surgery, 54 6, 1159-1163Múnera, Jorge O; Sundaram, Nambirajan; Rankin, Scott A; Hill, David; Watson, Carey; Mahe, Maxime; Vallance, Jefferson E; Shroyer, Noah F; Sinagoga, Katie L; Zarzoso-Lacoste, Adrian; Hudson, Jonathan R; Howell, Jonathan C; Chatuvedi, Praneet; Spence, Jason R; Shannon, John M; Zorn, Aaron M; Helmrath, Michael A; Wells, James M 2019. Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling. Cell stem cell, 24 5, 829Noah, Taeko K; Knoop, Kathryn A; McDonald, Keely G; Gustafsson, Jenny K; Waggoner, Lisa; Vanoni, Simone; Batie, Matthew; Arora, Kavisha; Naren, Anjaparavanda P; Wang, Yui-Hsi; Lukacs, Nicholas W; Munitz, Ariel; Helmrath, Michael A; Mahe, Maxime M; Newberry, Rodney D; Hogan, Simon P 2019. IL-13-induced intestinal secretory epithelial cell antigen passages are required for IgE-mediated food-induced anaphylaxis. The Journal of allergy and clinical immunology, 144 4, 1058-1073.e3Sitzman, Thomas J; Carle, Adam C; Heaton, Pamela C; Helmrath, Michael A; Britto, Maria T 2019. Five-Fold Variation Among Surgeons and Hospitals in the Use of Secondary Palate Surgery. The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 56 5, 586-594Steele, Nina G; Chakrabarti, Jayati; Wang, Jiang; Biesiada, Jacek; Holokai, Loryn; Chang, Julie; Nowacki, Lauren M; Hawkins, Jennifer; Mahe, Maxime; Sundaram, Nambirajan; Shroyer, Noah; Medvedovic, Mario; Helmrath, Michael; Ahmad, Syed; Zavros, Yana 2019. An Organoid-Based Preclinical Model of Human Gastric Cancer. Cellular and molecular gastroenterology and hepatology, 7 1, 161-184Brode, Cassie; Ratcliff, Megan; Reiter-Purtill, Jennifer; Hunsaker, Sanita; Helmrath, Michael; Zeller, Meg 2018. Predictors of Preoperative Program Non-Completion in Adolescents Referred for Bariatric Surgery. Obesity surgery, 28 9, 2853-2859Cortez, Alexander R; Poling, Holly M; Brown, Nicole E; Singh, Akaljot; Mahe, Maxime M; Helmrath, Michael A 2018. Transplantation of human intestinal organoids into the mouse mesentery: A more physiologic and anatomic engraftment site. Surgery, 164 4, 643-650Cushing, Christopher C; Threlkeld, Melody R S; Martinez-Leo, Bruno; Hall, Jennifer; Hossain, Monir; Dickie, Belinda H; Rymeski, Beth; Helmrath, Michael; Zeller, Meg H; Frischer, Jason S 2018. Initial development and validation of a fecal incontinence-specific quality of life measure. Journal of pediatric surgery, 53 6, 1148-1153Kelly, Daniel; Kotliar, Michael; Woo, Vivienne; Jagannathan, Sajjeev; Whitt, Jordan; Moncivaiz, Jessica; Aronow, Bruce J; Dubinsky, Marla C; Hyams, Jeffrey S; Markowitz, James F; Baldassano, Robert N; Stephens, Michael C; Walters, Thomas D; Kugathasan, Subra; Haberman, Yael; Sundaram, Nambirajan; Rosen, Michael J; Helmrath, Michael; Karns, Rebekah; Barski, Artem; Denson, Lee A; Alenghat, Theresa 2018. Microbiota-sensitive epigenetic signature predicts inflammation in Crohn's disease. JCI insight, 3 18, Lal, Dave R; Gadepalli, Samir K; Downard, Cynthia D; Ostlie, Daniel J; Minneci, Peter C; Swedler, Ruth M; Chelius, Thomas H; Cassidy, Laura; Rapp, Cooper T; Billmire, Deborah; Bruch, Steven; Burns, R Carland; Deans, Katherine J; Fallat, Mary E; Fraser, Jason D; Grabowski, Julia; Hebel, Ferdynand; Helmrath, Michael A; Hirschl, Ronald B; Kabre, Rashmi; Kohler, Jonathan; Landman, Matthew P; Leys, Charles M; Mak, Grace Z; Raque, Jessica; Rymeski, Beth; Saito, Jacqueline M; St Peter, Shawn D; von Allmen, Daniel; Warner, Brad W; Sato, Thomas T 2018. Challenging surgical dogma in the management of proximal esophageal atresia with distal tracheoesophageal fistula: Outcomes from the Midwest Pediatric Surgery Consortium. Journal of pediatric surgery, 53 7, 1267-1272Marchix, Justine; Goddard, Gillian; Helmrath, Michael A 2018. Host-Gut Microbiota Crosstalk in Intestinal Adaptation. Cellular and molecular gastroenterology and hepatology, 6 2, 149-162Michalsky, Marc P; Inge, Thomas H; Jenkins, Todd M; Xie, Changchun; Courcoulas, Anita; Helmrath, Michael; Brandt, Mary L; Harmon, Carroll M; Chen, Mike; Dixon, John B; Urbina, Elaine M 2018. Cardiovascular Risk Factors After Adolescent Bariatric Surgery. Pediatrics, 141 2, Minneci, Peter C; Kabre, Rashmi S; Mak, Grace Z; Halleran, Devin R; Cooper, Jennifer N; Afrazi, Amin; Calkins, Casey M; Downard, Cynthia D; Ehrlich, Peter; Fraser, Jason; Gadepalli, Samir K; Helmrath, Michael A; Kohler, Jonathan E; Landisch, Rachel; Landman, Matthew P; Lee, Constance; Leys, Charles M; Lodwick, Daniel L; Mon, Rodrigo; McClure, Beth; Rymeski, Beth; Saito, Jacqueline M; Sato, Thomas T; St Peter, Shawn D; Wood, Richard; Levitt, Marc A; Deans, Katherine J 2018. Screening practices and associated anomalies in infants with anorectal malformations: Results from the Midwest Pediatric Surgery Consortium. Journal of pediatric surgery, 53 6, 1163-1167Poling, Holly M; Wu, David; Brown, Nicole; Baker, Michael; Hausfeld, Taylor A; Huynh, Nhan; Chaffron, Samuel; Dunn, James C Y; Hogan, Simon P; Wells, James M; Helmrath, Michael A; Mahe, Maxime M 2018. Mechanically induced development and maturation of human intestinal organoids in vivo. Nature biomedical engineering, 2 6, 429-442Sinagoga, Katie L; McCauley, Heather A; Múnera, Jorge O; Reynolds, Nichole A; Enriquez, Jacob R; Watson, Carey; Yang, Hsiu-Chiung; Helmrath, Michael A; Wells, James M 2018. Deriving functional human enteroendocrine cells from pluripotent stem cells. Development (Cambridge, England), 145 19, Takebe, Takanori; Wells, James M; Helmrath, Michael A; Zorn, Aaron M 2018. Organoid Center Strategies for Accelerating Clinical Translation. Cell stem cell, 22 6, 806-809Asai, Akihiro; Aihara, Eitaro; Watson, Carey; Mourya, Reena; Mizuochi, Tatsuki; Shivakumar, Pranavkumar; Phelan, Kieran; Mayhew, Christopher; Helmrath, Michael; Takebe, Takanori; Wells, James; Bezerra, Jorge A 2017. Paracrine signals regulate human liver organoid maturation from induced pluripotent stem cells. Development (Cambridge, England), 144 6, 1056-1064Bertaux-Skeirik, Nina; Wunderlich, Mark; Teal, Emma; Chakrabarti, Jayati; Biesiada, Jacek; Mahe, Maxime; Sundaram, Nambirajan; Gabre, Joel; Hawkins, Jennifer; Gao, Jian; Engevik, Amy C; Yang, Li; Wang, Jiang; Goldenring, James R; Qualls, Joseph E; Medvedovic, Mario; Helmrath, Michael A; Diwan, Tayyab; Mulloy, James C; Zavros, Yana 2017. CD44 variant isoform 9 emerges in response to injury and contributes to the regeneration of the gastric epithelium. The Journal of pathology, , Inge, Thomas H; Jenkins, Todd M; Xanthakos, Stavra A; Dixon, John B; Daniels, Stephen R; Zeller, Meg H; Helmrath, Michael A 2017. Long-term outcomes of bariatric surgery in adolescents with severe obesity (FABS-5+): a prospective follow-up analysis. The lancet. Diabetes & endocrinology, 5 3, 165-173Mahe, Maxime M; Brown, Nicole E; Poling, Holly M; Helmrath, Michael A 2017. Erratum to: In Vivo Model of Small Intestine. Methods in molecular biology (Clifton, N.J.), 1597 , E1Maxime, Mahe M; Brown, Nicole E; Poling, Holly M; Michael, Helmrath A 2017. In Vivo Model of Small Intestine. Methods in molecular biology (Clifton, N.J.), 1597 , 229-245Múnera, Jorge O; Sundaram, Nambirajan; Rankin, Scott A; Hill, David; Watson, Carey; Mahe, Maxime; Vallance, Jefferson E; Shroyer, Noah F; Sinagoga, Katie L; Zarzoso-Lacoste, Adrian; Hudson, Jonathan R; Howell, Jonathan C; Chatuvedi, Praneet; Spence, Jason R; Shannon, John M; Zorn, Aaron M; Helmrath, Michael A; Wells, James M 2017. Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling. Cell stem cell, 21 1, 51-64.e6Nalapareddy, Kodandaramireddy; Nattamai, Kalpana J; Kumar, Rupali S; Karns, Rebekah; Wikenheiser-Brokamp, Kathryn A; Sampson, Leesa L; Mahe, Maxime M; Sundaram, Nambirajan; Yacyshyn, Mary-Beth; Yacyshyn, Bruce; Helmrath, Michael A; Zheng, Yi; Geiger, Hartmut 2017. Canonical Wnt Signaling Ameliorates Aging of Intestinal Stem Cells. Cell reports, 18 11, 2608-2621Sarwer, David B; Dilks, Rebecca J; Spitzer, Jacqueline C; Berkowitz, Robert I; Wadden, Thomas A; Moore, Renee H; Chittams, Jesse L; Brandt, Mary L; Chen, Mike K; Courcoulas, Anita P; Harmon, Carroll M; Helmrath, Michael A; Michalsky, Marc P; Xanthakos, Stavra A; Zeller, Meg H; Jenkins, Todd M; Inge, Thomas H 2017. Changes in Dietary Intake and Eating Behavior in Adolescents After Bariatric Surgery: an Ancillary Study to the Teen-LABS Consortium. Obesity surgery, 27 12, 3082-3091Wessel, Jacqueline; Kotagal, Meera; Helmrath, Michael A 2017. Management of Pediatric Intestinal Failure. Advances in pediatrics, 64 1, 253-267Workman, Michael J; Mahe, Maxime M; Trisno, Stephen; Poling, Holly M; Watson, Carey L; Sundaram, Nambirajan; Chang, Ching-Fang; Schiesser, Jacqueline; Aubert, Philippe; Stanley, Edouard G; Elefanty, Andrew G; Miyaoka, Yuichiro; Mandegar, Mohammad A; Conklin, Bruce R; Neunlist, Michel; Brugmann, Samantha A; Helmrath, Michael A; Wells, James M 2017. Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system. Nature medicine, 23 1, 49-59Zeller, Meg H; Pendery, Emma C; Reiter-Purtill, Jennifer; Hunsaker, Sanita L; Jenkins, Todd M; Helmrath, Michael A; Inge, Thomas H 2017. From adolescence to young adulthood: trajectories of psychosocial health following Roux-en-Y gastric bypass. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, , Cohran, Valeria; Managlia, Elizabeth; Bradford, Emily M; Goretsky, Tatiana; Li, Ting; Katzman, Rebecca B; Cheresh, Paul; Brown, Jeffrey B; Hawkins, Jennifer; Liu, Shirley X L; De Plaen, Isabelle G; Weitkamp, Jörn-Hendrik; Helmrath, Michael; Zhang, Zheng; Barrett, Terrence A 2016. Epithelial PIK3R1 (p85) and TP53 Regulate Survivin Expression during Adaptation to Ileocecal Resection. The American journal of pathology, 186 7, 1837-46Cushing, Christopher C; Martinez-Leo, Bruno; Bischoff, Andrea; Hall, Jennifer; Helmrath, Michael; Dickie, Belinda H; Levitt, Marc A; Peña, Alberto; Zeller, Meg H; Frischer, Jason S 2016. Health-Related Quality of Life and Parental Stress in Children With Fecal Incontinence: A Normative Comparison. Journal of pediatric gastroenterology and nutrition, 63 6, 633-636Engevik, Amy C; Feng, Rui; Choi, Eunyoung; White, Shana; Bertaux-Skeirik, Nina; Li, Jing; Mahe, Maxime M; Aihara, Eitaro; Yang, Li; DiPasquale, Betsy; Oh, Sunghee; Engevik, Kristen A; Giraud, Andrew S; Montrose, Marshall H; Medvedovic, Mario; Helmrath, Michael A; Goldenring, James R; Zavros, Yana 2016. The Development of Spasmolytic Polypeptide/TFF2-Expressing Metaplasia (SPEM) During Gastric Repair Is Absent in the Aged Stomach. Cellular and molecular gastroenterology and hepatology, 2 5, 605-624Hirschl, Ronald B; Minneci, Peter; Gadepalli, Samir; Saito, Jacqueline M; Askegard-Giesmann, Johanna; Deans, Katherine; Downard, Cynthia; Fallat, Mary; Finnell, Maria; Helmrath, Michael; Kabre, Rashmi; Lal, David; Leys, Charles; Mak, Grace; Ostlie, Daniel; Rescorla, Fred; Sato, Thomas; St Peter, Shawn; von Allmen, Daniel; Warner, Brad 2016. Development of a multi-institutional clinical research consortium for pediatric surgery. Journal of pediatric surgery, , Inge, Thomas H; Courcoulas, Anita P; Jenkins, Todd M; Michalsky, Marc P; Helmrath, Michael A; Brandt, Mary L; Harmon, Carroll M; Zeller, Meg H; Chen, Mike K; Xanthakos, Stavra A; Horlick, Mary; Buncher, C Ralph 2016. Weight Loss and Health Status 3 Years after Bariatric Surgery in Adolescents. The New England journal of medicine, 374 2, 113-23Lal, Dave R; Gadepalli, Samir K; Downard, Cynthia D; Ostlie, Daniel J; Minneci, Peter C; Swedler, Ruth M; Chelius, Thomas; Cassidy, Laura; Rapp, Cooper T; Deans, Katherine J; Fallat, Mary E; Finnell, S Maria E; Helmrath, Michael A; Hirschl, Ronald B; Kabre, Rashmi S; Leys, Charles M; Mak, Grace; Raque, Jessica; Rescorla, Frederick J; Saito, Jacqueline M; St Peter, Shawn D; von Allmen, Daniel; Warner, Brad W; Sato, Thomas T 2016. Perioperative management and outcomes of esophageal atresia and tracheoesophageal fistula. Journal of pediatric surgery, , Mezoff, Ethan A; Hawkins, Jennifer A; Ollberding, Nicholas J; Karns, Rebekah; Morrow, Ardythe L; Helmrath, Michael A 2016. The human milk oligosaccharide 2'-fucosyllactose augments the adaptive response to extensive intestinal. American journal of physiology. Gastrointestinal and liver physiology, 310 6, G427-38Aihara, Eitaro; Mahe, Maxime M; Schumacher, Michael A; Matthis, Andrea L; Feng, Rui; Ren, Wenwen; Noah, Taeko K; Matsu-ura, Toru; Moore, Sean R; Hong, Christian I; Zavros, Yana; Herness, Scott; Shroyer, Noah F; Iwatsuki, Ken; Jiang, Peihua; Helmrath, Michael A; Montrose, Marshall H 2015. Characterization of stem/progenitor cell cycle using murine circumvallate papilla taste bud organoid. Scientific reports, 5 , 17185Bout-Tabaku, Sharon; Michalsky, Marc P; Jenkins, Todd M; Baughcum, Amy; Zeller, Meg H; Brandt, Mary L; Courcoulas, Anita; Buncher, Ralph; Helmrath, Michael; Harmon, Carroll M; Chen, Mike K; Inge, Thomas H 2015. Musculoskeletal Pain, Self-reported Physical Function, and Quality of Life in the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) Cohort. JAMA pediatrics, 169 6, 552-9Michalsky, Marc P; Inge, Thomas H; Simmons, Mark; Jenkins, Todd M; Buncher, Ralph; Helmrath, Michael; Brandt, Mary L; Harmon, Carroll M; Courcoulas, Anita; Chen, Michael; Horlick, Mary; Daniels, Stephen R; Urbina, Elaine M 2015. Cardiovascular Risk Factors in Severely Obese Adolescents: The Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) Study. JAMA pediatrics, 169 5, 438-44Moon, Changsuk; Zhang, Weiqiang; Sundaram, Nambirajan; Yarlagadda, Sunitha; Reddy, Vadde Sudhakar; Arora, Kavisha; Helmrath, Michael A; Naren, Anjaparavanda P 2015. Drug-induced secretory diarrhea: A role for CFTR. Pharmacological research, 102 , 107-12Xanthakos, Stavra A; Jenkins, Todd M; Kleiner, David E; Boyce, Tawny W; Mourya, Reena; Karns, Rebekah; Brandt, Mary L; Harmon, Carroll M; Helmrath, Michael A; Michalsky, Marc P; Courcoulas, Anita P; Zeller, Meg H; Inge, Thomas H 2015. High Prevalence of Nonalcoholic Fatty Liver Disease in Adolescents Undergoing Bariatric Surgery. Gastroenterology, , Zeller, Meg H; Inge, Thomas H; Modi, Avani C; Jenkins, Todd M; Michalsky, Marc P; Helmrath, Michael; Courcoulas, Anita; Harmon, Carroll M; Rofey, Dana; Baughcum, Amy; Austin, Heather; Price, Karin; Xanthakos, Stavra A; Brandt, Mary L; Horlick, Mary; Buncher, Ralph 2015. Severe obesity and comorbid condition impact on the weight-related quality of life of the adolescent patient. The Journal of pediatrics, 166 3, 651-9.e4Inge, Thomas H; Boyce, Tawny W; Lee, Margaret; Kollar, Linda; Jenkins, Todd M; Brandt, Mary L; Helmrath, Michael; Xanthakos, Stavra A; Zeller, Meg H; Harmon, Carroll M; Courcoulas, Anita; Michalsky, Marc P 2014. Access to care for adolescents seeking weight loss surgery. Obesity (Silver Spring, Md.), 22 12, 2593-7Inge, Thomas H; Zeller, Meg H; Jenkins, Todd M; Helmrath, Michael; Brandt, Mary L; Michalsky, Marc P; Harmon, Carroll M; Courcoulas, Anita; Horlick, Mary; Xanthakos, Stavra A; Dolan, Larry; Mitsnefes, Mark; Barnett, Sean J; Buncher, Ralph 2014. Perioperative outcomes of adolescents undergoing bariatric surgery: the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study. JAMA pediatrics, 168 1, 47-53Michalsky, Marc P; Inge, Thomas H; Teich, Steven; Eneli, Ihuoma; Miller, Rosemary; Brandt, Mary L; Helmrath, Michael; Harmon, Carroll M; Zeller, Meg H; Jenkins, Todd M; Courcoulas, Anita; Buncher, Ralph C 2014. Adolescent bariatric surgery program characteristics: the Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study experience. Seminars in pediatric surgery, 23 1, 5-10Xiao, Nianzhou; Jenkins, Todd M; Nehus, Edward; Inge, Thomas H; Michalsky, Marc P; Harmon, Carroll M; Helmrath, Michael A; Brandt, Mary L; Courcoulas, Anita; Moxey-Mims, Marva; Mitsnefes, Mark M 2014. Kidney function in severely obese adolescents undergoing bariatric surgery. Obesity (Silver Spring, Md.), 22 11, 2319-25Eradi, Balgopal; Hamrick, Miller; Bischoff, Andrea; Frischer, Jason S; Helmrath, Michael; Hall, Jennifer; Peña, Alberto; Levitt, Marc A 2013. The role of a colon resection in combination with a Malone appendicostomy as part of a bowel management program for the treatment of fecal incontinence. Journal of pediatric surgery, 48 11, 2296-300Ubesie, Agozie C; Kocoshis, Samuel A; Mezoff, Adam G; Henderson, Carol J; Helmrath, Michael A; Cole, Conrad R 2013. Multiple micronutrient deficiencies among patients with intestinal failure during and after transition to enteral nutrition. The Journal of pediatrics, 163 6, 1692-6Dehmer, Jeffrey J; Fuller, Megan K; Helmrath, Michael A 2011. Management of pediatric intestinal failure. Advances in pediatrics, 58 1, 181-94Hamrick, Miller; Helmrath, Michael; Bischoff, Andrea; Eradi, Balgopal; Levitt, Marc; Peña, Alberto 2011. Letter to the Editor regarding comparison of anorectal angle and continence after Georgeson and Peña procedures for high/intermediate imperforate anus. Journal of pediatric surgery, 46 5, 1019-20; author replBrandt, Mary L; Harmon, Carroll M; Helmrath, Michael A; Inge, Thomas H; McKay, Siripoom V; Michalsky, Marc P 2010. Morbid obesity in pediatric diabetes mellitus: surgical options and outcomes. Nature reviews. Endocrinology, 6 11, 637-45Inge, Thomas; Helmrath, Michael; Vierra, Mark 2010. The Santoro III massive enterectomy: how can we justify the risks in obese adolescents? Obesity surgery, 20 12, 1718-9Garrison, Aaron P; Helmrath, Michael A; Dekaney, Christopher M 2009. Intestinal stem cells. Journal of pediatric gastroenterology and nutrition, 49 1, 2-7Inge, Thomas H; Miyano, Go; Bean, Judy; Helmrath, Michael; Courcoulas, Anita; Harmon, Carroll M; Chen, Mike K; Wilson, Kimberly; Daniels, Stephen R; Garcia, Victor F; Brandt, Mary L; Dolan, Lawrence M 2009. Reversal of type 2 diabetes mellitus and improvements in cardiovascular risk factors after surgical weight loss in adolescents. Pediatrics, 123 1, 214-22Inge, Thomas; Helmrath, Michael; Vierra, Mark; Ikramuddin, Sayeed 2008. Challenges of adolescent bariatric surgery: tips for managing the extremely obese teen. Journal of laparoendoscopic & advanced surgical techniques. Part A, 18 1, 157-69De Silva, Nirupama K; Helmrath, Michael A; Klish, William J 2007. Obesity in the adolescent female. Journal of pediatric and adolescent gynecology, 20 3, 207-13Fuller, Megan K; Helmrath, Michael A 2007. Thoracic empyema, application of video-assisted thoracic surgery and its current management. Current opinion in pediatrics, 19 3, 328-32Inge, Thomas H; Zeller, Meg; Harmon, Carroll; Helmrath, Michael; Bean, Judy; Modi, Avani; Horlick, Mary; Kalra, Maninder; Xanthakos, Stavra; Miller, Rosemary; Akers, Rachel; Courcoulas, Anita 2007. Teen-Longitudinal Assessment of Bariatric Surgery: methodological features of the first prospective multicenter study of adolescent bariatric surgery. Journal of pediatric surgery, 42 11, 1969-71Helmrath, Michael A; Brandt, Mary L; Inge, Thomas H 2006. Adolescent obesity and bariatric surgery. The Surgical clinics of North America, 86 2, 441-54, xKenton, Alexander B; Hegemier, Suzanne; Smith, E O'Brian; O'Donovan, Donough J; Brandt, Mary L; Cass, Darrell L; Helmrath, Michael A; Washburn, Kimberly; Weihe, Elizabeth K; Fernandes, Caraciolo J 2005. Platelet transfusions in infants with necrotizing enterocolitis do not lower mortality but may increase morbidity. Journal of perinatology : official journal of the California Perinatal Association, 25 3, 173-7Kenton, Alexander B; O'Donovan, Donough; Cass, Darrell L; Helmrath, Michael A; Smith, E O'brian; Fernandes, Caraciolo J; Washburn, Kimberly; Weihe, Elizabeth K; Brandt, Mary L 2005. Severe thrombocytopenia predicts outcome in neonates with necrotizing enterocolitis. Journal of perinatology : official journal of the California Perinatal Association, 25 1, 14-20Inge, Thomas H; Krebs, Nancy F; Garcia, Victor F; Skelton, Joseph A; Guice, Karen S; Strauss, Richard S; Albanese, Craig T; Brandt, Mary L; Hammer, Lawrence D; Harmon, Carol M; Kane, Timothy D; Klish, William J; Oldham, Keith T; Rudolph, Colin D; Helmrath, Michael A; Donovan, Edward; Daniels, Stephen R 2004. Bariatric surgery for severely overweight adolescents: concerns and recommendations. Pediatrics, 114 1, 217-23Klish, William J; Brandt, Mary L; Helmrath, Michael A 2004. Obesity surgery in pediatrics. Journal of pediatric gastroenterology and nutrition, 39 1, 2-4
Bouffi, Carine; Wikenheiser-Brokamp, Kathryn A; Chaturvedi, Praneet; Sundaram, Nambirajan; Goddard, Gillian R; Wunderlich, Mark; Brown, Nicole E; Staab, Janet F; Latanich, Rachel; Zachos, Nicholas C; Holloway, Emily M; Mahe, Maxime M; Poling, Holly M; Vales, Simon; Fisher, Garrett W; Spence, Jason R; Mulloy, James C; Zorn, Aaron M; Wells, James M; Helmrath, Michael A 2023. In vivo development of immune tissue in human intestinal organoids transplanted into humanized mice. Nature biotechnology, 41 6, 824-831Gil, Lindsay A; Lutz, Carley M; Dillon, Patrick A; Downard, Cynthia D; Ehrlich, Peter F; Fallat, Mary E; Fraser, Jason D; Grabowski, Julia E; Helmrath, Michael A; Hertweck, S Paige; Hirschl, Ronald B; Kabre, Rashmi; Lal, Dave R; Landman, Matthew P; Lawrence, Amy E; Leys, Charles M; Mak, Grace Z; Markel, Troy A; Raiji, Manish T; Rymeski, Beth; Saito, Jacqueline M; Sato, Thomas T; St Peter, Shawn D; Stafford, Linda M Cherney; Deans, Katherine J; Minneci, Peter C; Hewitt, Geri D; Aldrink, Jennifer H 2023. Use and Accuracy of Intraoperative Frozen Section Analysis for Ovarian Masses in Children and Adolescents. Journal of pediatric and adolescent gynecology, 36 2, 155-159Marquart, John P; Bowder, Alexis N; Bence, Christina M; St Peter, Shawn D; Gadepalli, Samir K; Sato, Thomas T; Szabo, Aniko; Minneci, Peter C; Hirschl, Ronald B; Rymeski, Beth A; Downard, Cynthia D; Markel, Troy A; Deans, Katherine J; Fallat, Mary E; Fraser, Jason D; Grabowski, Julia E; Helmrath, Michael A; Kabre, Rashmi D; Kohler, Jonathan E; Landman, Matthew P; Lawrence, Amy E; Leys, Charles M; Mak, Grace Z; Port, Elissa; Saito, Jacqueline; Silverberg, Jared; Slidell, Mark B; Wright, Tiffany N; Lal, Dave R 2023. Thoracoscopy versus thoracotomy for esophageal atresia and tracheoesophageal fistula: Outcomes from the Midwest Pediatric Surgery Consortium. Journal of pediatric surgery, 58 1, 27-33Moran-Lev, Hadar; Kocoshis, Samuel A; Oliveira, Stephanie B; Helmrath, Michael; Cole, Conrad R 2023. Chronic Mucosal Inflammation in Pediatric Intestinal Failure Patients- a Unique Phenomenon. Journal of pediatric gastroenterology and nutrition, , O'Connell, Amy E; Raveenthiraraj, Sathuwarman; Adegboye, Comfort; Qi, Wanshu; Khetani, Radhika S; Singh, Akaljot; Sundaram, Nambirajam; Emeonye, Chidera; Lin, Jasmine; Goldsmith, Jeffrey D; Thiagarajah, Jay R; Carlone, Diana L; Turner, Jerrold R; Agrawal, Pankaj B; Helmrath, Michael; Breault, David T 2023. WNT2B Deficiency Causes Increased Susceptibility to Colitis in Mice and Impairs Intestinal Epithelial Development in Humans. bioRxiv : the preprint server for biology, , Singh, Akaljot; Poling, Holly M; Chaturvedi, Praneet; Thorner, Konrad; Sundaram, Nambirajan; Kechele, Daniel O; Childs, Charlie J; McCauley, Heather A; Fisher, Garrett W; Brown, Nicole E; Spence, Jason R; Wells, James M; Helmrath, Michael A 2023. Transplanted human intestinal organoids: a resource for modeling human intestinal development. Development (Cambridge, England), 150 9, Zeller, Meg H; Strong, Heather; Reiter-Purtill, Jennifer; Jenkins, Todd M; Mitchell, James E; Michalsky, Marc P; Helmrath, Michael A 2023. Marijuana, e-cigarette, and tobacco product use in young adults who underwent pediatric bariatric surgery. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 19 5, 512-521Bowder, Alexis N; Bence, Christina M; Rymeski, Beth A; Gadepalli, Samir K; Sato, Thomas T; Szabo, Aniko; Arendonk, Kyle Van; Minneci, Peter C; Downard, Cynthia D; Hirschl, Ronald B; Markel, Troy; Courtney, Cathleen M; Deans, Katherine J; Fallat, Mary E; Fraser, Jason D; Grabowski, Julia E; Helmrath, Michael A; Kabre, Rashmi D; Kohler, Jonathan E; Landman, Matthew P; Lawrence, Amy E; Leys, Charles M; Mak, Grace; Port, Elissa; Saito, Jacqueline; Silverberg, Jared; Slidell, Mark B; St Peter, Shawn D; Troutt, Misty; Wright, Tiffany N; Lal, Dave R 2022. Acid suppression duration does not alter anastomotic stricture rates after esophageal atresia with distal tracheoesophageal fistula repair: A prospective multi-institutional cohort study. Journal of pediatric surgery, 57 6, 975-980Capeling, Meghan M; Huang, Sha; Childs, Charlie J; Wu, Joshua H; Tsai, Yu-Hwai; Wu, Angeline; Garg, Neil; Holloway, Emily M; Sundaram, Nambirajan; Bouffi, Carine; Helmrath, Michael; Spence, Jason R 2022. Suspension culture promotes serosal mesothelial development in human intestinal organoids. Cell reports, 38 7, 110379Chakrabarti, Jayati; Dua-Awereh, Martha; Schumacher, Michael; Engevik, Amy; Hawkins, Jennifer; Helmrath, Michael A; Zavros, Yana 2022. Sonic Hedgehog acts as a macrophage chemoattractant during regeneration of the gastric epithelium. NPJ Regenerative medicine, 7 1, 3Decker, Kristina M; Reiter-Purtill, Jennifer; Bejarano, Carolina M; Goldschmidt, Andrea B; Mitchell, James E; Jenkins, Todd M; Helmrath, Michael; Inge, Thomas H; Michalsky, Marc P; Zeller, Meg H 2022. Psychosocial predictors of problematic eating in young adults who underwent adolescent bariatric surgery. Obesity science & practice, 8 5, 545-555Dekonenko, Charlene; Fraser, Jason D; Deans, Katherine; Fallat, Mary E; Helmrath, Michael; Kabre, Rashmi; Leys, Charles M; Burns, R Cartland; Corkum, Kristine; Dillon, Patrick A; Downard, Cynthia; Wright, Tiffany N; Gadepalli, Samir K; Grabowski, Julia; Hernandez, Edward; Hirschl, Ronald; Johnson, Kevin N; Kohler, Jonathan; Landman, Matthew P; Landisch, Rachel M; Lawrence, Amy E; Mak, Grace Z; Minneci, Peter; Rymeski, Beth; Sato, Thomas T; Slater, Bethany J; Peter, St Shawn D 2022. Does Use of a Feeding Protocol Change Outcomes in Gastroschisis? A Report from the Midwest Pediatric Surgery Consortium. European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 32 2, 153-159Ding, Lin; Chakrabarti, Jayati; Sheriff, Sulaiman; Li, Qian; Thi Hong, Hahn Nguyen; Sontz, Ricky A; Mendoza, Zoe E; Schreibeis, Amanda; Helmrath, Michael A; Zavros, Yana; Merchant, Juanita L 2022. Toll-like Receptor 9 Pathway Mediates Schlafen+-MDSC Polarization During Helicobacter-induced Gastric Metaplasias. Gastroenterology, 163 2, 411-425.e4Eicher, Alexandra K; Kechele, Daniel O; Sundaram, Nambirajan; Berns, H Matthew; Poling, Holly M; Haines, Lauren E; Sanchez, J Guillermo; Kishimoto, Keishi; Krishnamurthy, Mansa; Han, Lu; Zorn, Aaron M; Helmrath, Michael A; Wells, James M 2022. Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells. Cell stem cell, 29 1, 36-51.e6Engwall-Gill, Abigail J; Chan, Sherwin S; Boyd, Kevin P; Saito, Jacqueline M; Fallat, Mary E; St Peter, Shawn D; Bolger-Theut, Stephanie; Crotty, Eric J; Green, Jared R; Hulett Bowling, Rebecca L; Kumbhar, Sachin S; Rattan, Mantosh S; Young, Cody M; Canner, Joseph K; Deans, Katherine J; Gadepalli, Samir K; Helmrath, Michael A; Hirschl, Ronald B; Kabre, Rashmi; Lal, Dave R; Landman, Matthew P; Leys, Charles M; Mak, Grace Z; Minneci, Peter C; Wright, Tiffany N; Kunisaki, Shaun M 2022. Accuracy of Chest Computed Tomography in Distinguishing Cystic Pleuropulmonary Blastoma From Benign Congenital Lung Malformations in Children. JAMA network open, 5 6, e2219814Fraser, James A; Deans, Katherine J; Fallat, Mary E; Helmrath, Michael; Kabre, Rashmi; Leys, Charles M; Markel, Troy A; Dillon, Patrick A; Downard, Cynthia; Wright, Tiffany N; Gadepalli, Samir K; Grabowski, Julia E; Hirschl, Ronald; Johnson, Kevin N; Kohler, Jonathan E; Landman, Matthew P; Mak, Grace Z; Minneci, Peter C; Rymeski, Beth; Sato, Thomas T; Slater, Bethany J; Peter, Shawn D St; Fraser, Jason D 2022. Evaluating the risk of peri-umbilical hernia after sutured or sutureless gastroschisis closure. Journal of pediatric surgery, 57 12, 786-791Kunisaki, Shaun M; Saito, Jacqueline M; Fallat, Mary E; Peter, Shawn D St; Lal, Dave R; Karmakar, Monita; Deans, Katherine J; Gadepalli, Samir K; Hirschl, Ronald B; Minneci, Peter C; Helmrath, Michael A 2022. Fetal Risk Stratification and Outcomes in Children with Prenatally Diagnosed Lung Malformations: Results from a Multi-Institutional Research Collaborative. Annals of surgery, 276 5, e622-e630McNelis, Kera; Poindexter, Anne; Goddard, Gillian; Riddle, Stefanie; Wessel, Jacqueline; Helmrath, Michael 2022. Body Composition of Infants With Congenital Gastroschisis. Journal of pediatric gastroenterology and nutrition, 74 2, e35-e38Minneci, Peter C; Hade, Erinn M; Gil, Lindsay A; Metzger, Gregory A; Saito, Jacqueline M; Mak, Grace Z; Hirschl, Ronald B; Gadepalli, Samir; Helmrath, Michael A; Leys, Charles M; Sato, Thomas T; Lal, Dave R; Landman, Matthew P; Kabre, Rashmi; Fallat, Mary E; Cooper, Jennifer N; Deans, Katherine J 2022. Demographic and Clinical Characteristics Associated With the Failure of Nonoperative Management of Uncomplicated Appendicitis in Children: Secondary Analysis of a Nonrandomized Clinical Trial. JAMA network open, 5 5, e229712Pitstick, Amy L; Poling, Holly M; Sundaram, Nambirajan; Lewis, Phillip L; Kechele, Daniel O; Sanchez, J Guillermo; Scott, Melissa A; Broda, Taylor R; Helmrath, Michael A; Wells, James M; Mayhew, Christopher N 2022. Aggregation of cryopreserved mid-hindgut endoderm for more reliable and reproducible hPSC-derived small intestinal organoid generation. Stem cell reports, 17 8, 1889-1902Rosselot, Andrew E; Park, Miri; Kim, Mari; Matsu-Ura, Toru; Wu, Gang; Flores, Danilo E; Subramanian, Krithika R; Lee, Suengwon; Sundaram, Nambirajan; Broda, Taylor R; McCauley, Heather A; Hawkins, Jennifer A; Chetal, Kashish; Salomonis, Nathan; Shroyer, Noah F; Helmrath, Michael A; Wells, James M; Hogenesch, John B; Moore, Sean R; Hong, Christian I 2022. Ontogeny and function of the circadian clock in intestinal organoids. The EMBO journal, 41 2, e106973Arora, Kavisha; Yang, Fanmuyi; Brewington, John; McPhail, Gary; Cortez, Alexander R; Sundaram, Nambirajan; Ramananda, Yashaswini; Ogden, Herbert; Helmrath, Michael; Clancy, John P; Naren, Anjaparavanda P 2021. Patient personalized translational tools in cystic fibrosis to transform data from bench to bed-side and back. American journal of physiology. Gastrointestinal and liver physiology, 320 6, G1123-G1130Bence, Christina M; Rymeski, Beth; Gadepalli, Samir; Sato, Thomas T; Minneci, Peter C; Downard, Cynthia; Hirschl, Ronald B; Amin, Ruchi A; Burns, R Cartland; Cherney-Stafford, Linda; Courtney, Cathleen M; Deans, Katherine J; Fallat, Mary E; Fraser, Jason D; Grabowski, Julia E; Helmrath, Michael A; Kabre, Rashmi D; Kohler, Jonathan E; Landman, Matthew P; Lawrence, Amy E; Leys, Charles M; Mak, Grace Z; Port, Elissa; Saito, Jacqueline M; Silverberg, Jared; Slidell, Mark B; St Peter, Shawn D; Troutt, Misty; Walker, Sarah; Wright, Tiffany; Lal, Dave R 2021. Clinical outcomes following implementation of a management bundle for esophageal atresia with distal tracheoesophageal fistula. Journal of pediatric surgery, 56 1, 47-54Chakrabarti, Jayati; Koh, Vivien; Steele, Nina; Hawkins, Jennifer; Ito, Yoshiaki; Merchant, Juanita L; Wang, Jiang; Helmrath, Michael A; Ahmad, Syed A; So, Jimmy Bok Yan; Yong, Wei Peng; Zavros, Yana 2021. Disruption of Her2-Induced PD-L1 Inhibits Tumor Cell Immune Evasion in Patient-Derived Gastric Cancer Organoids. Cancers, 13 24, Chan, Calvin C; Harley, Isaac T W; Pfluger, Paul T; Trompette, Aurelien; Stankiewicz, Traci E; Allen, Jessica L; Moreno-Fernandez, Maria E; Damen, Michelle S M A; Oates, Jarren R; Alarcon, Pablo C; Doll, Jessica R; Flick, Matthew J; Flick, Leah M; Sanchez-Gurmaches, Joan; Mukherjee, Rajib; Karns, Rebekah; Helmrath, Michael; Inge, Thomas H; Weisberg, Stuart P; Pamp, Sünje J; Relman, David A; Seeley, Randy J; Tschöp, Matthias H; Karp, Christopher L; Divanovic, Senad 2021. A BAFF/APRIL axis regulates obesogenic diet-driven weight gain. Nature communications, 12 1, 2911Criss, Zachary K; Bhasin, Nobel; Di Rienzi, Sara C; Rajan, Anubama; Deans-Fielder, Kali; Swaminathan, Ganesh; Kamyabi, Nabiollah; Zeng, Xi-Lei; Doddapaneni, Harsha; Menon, Vipin K; Chakravarti, Deepavali; Estrella, Clarissa; Yu, Xiaomin; Patil, Ketki; Petrosino, Joseph F; Fleet, James C; Verzi, Michael P; Christakos, Sylvia; Helmrath, Michael A; Arimura, Sumimasa; DePinho, Ronald A; Britton, Robert A; Maresso, Anthony W; Grande-Allen, K Jane; Blutt, Sarah E; Crawford, Sue E; Estes, Mary K; Ramani, Sasirekha; Shroyer, Noah F 2021. Drivers of transcriptional variance in human intestinal epithelial organoids. Physiological genomics, 53 11, 486-508Dekonenko, Charlene; Fraser, Jason D; Deans, Katherine J; Fallat, Mary E; Helmrath, Michael; Kabre, Rashmi; Leys, Charles M; Burns, R Cartland; Corkumd, Kristine; Dillon, Patrick A; Downard, Cynthia; Wright, Tiffany N; Gadepalli, Samir K; Grabowski, Julia E; Hernandez, Edward; Hirschl, Ronald; Johnson, Kevin N; Kohler, Jonathan E; Landman, Matthew P; Landisch, Rachel M; Lawrence, Amy E; Mak, Grace Z; Minneci, Peter C; Rymeski, Beth; Sato, Thomas T; Slater, Bethany J; St Peter, Shawn D 2021. Outcomes in gastroschisis: expectations in the postnatal period for simple vs complex gastroschisis. Journal of perinatology : official journal of the California Perinatal Association, 41 7, 1755-1759Goddard, Gillian R; McNelis, Kera; Poindexter, Anne; Jenkins, Todd; Wessel, Jacqueline; Nathan, Amy T; Helmrath, Michael A; Poindexter, Brenda 2021. Quality Improvement Efforts Reduce Incidence of Surgical Necrotizing Enterocolitis and Related Deaths. American journal of perinatology, 38 13, 1386-1392Kasendra, Magdalena; Troutt, Misty; Broda, Taylor; Bacon, W Clark; Wang, Timothy C; Niland, Joyce C; Helmrath, Michael A 2021. Intestinal organoids: roadmap to the clinic. American journal of physiology. Gastrointestinal and liver physiology, 321 1, G1-G10Koh, Vivien; Chakrabarti, Jayati; Torvund, Meaghan; Steele, Nina; Hawkins, Jennifer A; Ito, Yoshiaki; Wang, Jiang; Helmrath, Michael A; Merchant, Juanita L; Ahmed, Syed A; Shabbir, Asim; Yan So, Jimmy Bok; Yong, Wei Peng; Zavros, Yana 2021. Hedgehog transcriptional effector GLI mediates mTOR-Induced PD-L1 expression in gastric cancer organoids. Cancer letters, 518 , 59-71Kunisaki, Shaun M; Lal, Dave R; Saito, Jacqueline M; Fallat, Mary E; St Peter, Shawn D; Fox, Zachary D; Heider, Amer; Chan, Sherwin S; Boyd, Kevin P; Burns, R Cartland; Deans, Katherine J; Gadepalli, Samir K; Hirschl, Ronald B; Kabre, Rashmi; Landman, Matthew P; Leys, Charles M; Mak, Grace Z; Minneci, Peter C; Wright, Tiffany N; Helmrath, Michael A 2021. Pleuropulmonary Blastoma in Pediatric Lung Lesions. Pediatrics, 147 4, Lim, Irene Isabel P; Cushing, Christopher C; Jenkins, Todd; Troutt, Misty; Zeller, Margaret H; Hossain, Monir; Rymeski, Beth; Helmrath, Michael; Frischer, Jason S 2021. Prospective quality of life outcomes in pediatric fecal incontinence following bowel management. Journal of pediatric surgery, 56 8, 1459-1464McNelis, Kera; Goddard, Gillian; Jenkins, Todd; Poindexter, Anne; Wessel, Jacqueline; Helmrath, Michael; Poindexter, Brenda 2021. Delay in achieving enteral autonomy and growth outcomes in very low birth weight infants with surgical necrotizing enterocolitis. Journal of perinatology : official journal of the California Perinatal Association, 41 1, 150-156Moreno-Fernandez, Maria E; Giles, Daniel A; Oates, Jarren R; Chan, Calvin C; Damen, Michelle S M A; Doll, Jessica R; Stankiewicz, Traci E; Chen, Xiaoting; Chetal, Kashish; Karns, Rebekah; Weirauch, Matthew T; Romick-Rosendale, Lindsey; Xanthakos, Stavra A; Sheridan, Rachel; Szabo, Sara; Shah, Amy S; Helmrath, Michael A; Inge, Thomas H; Deshmukh, Hitesh; Salomonis, Nathan; Divanovic, Senad 2021. PKM2-dependent metabolic skewing of hepatic Th17 cells regulates pathogenesis of non-alcoholic fatty liver disease. Cell metabolism, 33 6, 1187-1204.e9Shah, Amy S; Helmrath, Michael A; Inge, Thomas H; Xanthakos, Stavra A; Kelsey, Megan M; Jenkins, Todd; Trout, Andrew T; Browne, Lorna; Nadeau, Kristen J 2021. Study protocol: a prospective controlled clinical trial to assess surgical or medical treatment for paediatric type 2 diabetes (ST2OMP). BMJ open, 11 8, e047766Weller, Jennine H; Peter, Shawn D St; Fallat, Mary E; Saito, Jacqueline M; Burns, Cartland R; Deans, Katherine J; Fraser, Jason D; Gadepalli, Samir K; Helmrath, Michael A; Hirschl, Ronald B; Kabre, Rashmi; Lal, Dave R; Landman, Matthew P; Leys, Charles M; Mak, Grace Z; Minneci, Peter C; Wright, Tiffany N; Kunisaki, Shaun M 2021. Thoracoscopic versus open lobectomy in infants with congenital lung malformations: A multi-institutional propensity score analysis. Journal of pediatric surgery, 56 12, 2148-2156Chan, Calvin C; Damen, Michelle S M A; Moreno-Fernandez, Maria E; Stankiewicz, Traci E; Cappelletti, Monica; Alarcon, Pablo C; Oates, Jarren R; Doll, Jessica R; Mukherjee, Rajib; Chen, Xiaoting; Karns, Rebekah; Weirauch, Matthew T; Helmrath, Michael A; Inge, Thomas H; Divanovic, Senad 2020. Type I interferon sensing unlocks dormant adipocyte inflammatory potential. Nature communications, 11 1, 2745Dewberry, Lindel C; Jalivand, Anahita; Gupta, Resmi; Jenkins, Todd M; Beamish, Andrew; Inge, Thomas H; Courcoulas, Anita; Helmrath, Michael; Brandt, Mary L; Harmon, Carroll M; Chen, Mike; Dixon, John B; Zeller, Margaret; Michalsky, Marc P 2020. Weight Loss and Health Status 5 Years After Adjustable Gastric Banding in Adolescents. Obesity surgery, 30 6, 2388-2394Fraser, Jason D; Deans, Katherine J; Fallat, Mary E; Helmrath, Michael A; Kabre, Rashmi; Leys, Charles M; Burns, R Cartland; Corkum, Kristine; Dillon, Patrick A; Downard, Cynthia D; Gadepalli, Samir K; Grabowski, Julia E; Hernandez, Edward; Hirschl, Ronald B; Johnson, Kevin N; Kohler, Jonathan E; Landman, Matthew P; Landisch, Rachel M; Lawrence, Amy E; Mak, Grace Z; Minneci, Peter C; Rymeski, Beth; Sato, Thomas T; Scannell, Madeline; Slater, Bethany J; Wilkinson, Kathryn H; Wright, Tiffany N; St Peter, Shawn D 2020. Sutureless vs sutured abdominal wall closure for gastroschisis: Operative characteristics and early outcomes from the Midwest Pediatric Surgery Consortium. Journal of pediatric surgery, 55 11, 2284-2288Kunisaki, Shaun M; Saito, Jacqueline M; Fallat, Mary E; St Peter, Shawn D; Lal, Dave R; Johnson, Kevin N; Mon, Rodrigo A; Adams, Cheryl; Aladegbami, Bola; Bence, Christina; Burns, R Cartland; Corkum, Kristine S; Deans, Katherine J; Downard, Cynthia D; Fraser, Jason D; Gadepalli, Samir K; Helmrath, Michael A; Kabre, Rashmi; Landman, Matthew P; Leys, Charles M; Linden, Allison F; Lopez, Joseph J; Mak, Grace Z; Minneci, Peter C; Rademacher, Brooks L; Shaaban, Aimen; Walker, Sarah K; Wright, Tiffany N; Hirschl, Ronald B 2020. Development of a multi-institutional registry for children with operative congenital lung malformations. Journal of pediatric surgery, 55 7, 1313-1318Lamoshi, Abdulrouf; Chernoguz, Artur; Harmon, Carroll M; Helmrath, Michael 2020. Complications of bariatric surgery in adolescents. Seminars in pediatric surgery, 29 1, 150888Leys, Charles M; Hirschl, Ronald B; Kohler, Jonathan E; Cherney-Stafford, Linda; Marka, Nicholas; Fallat, Mary E; Gadepalli, Samir K; Fraser, Jason D; Grabowski, Julia; Burns, R Cartland; Downard, Cynthia D; Foley, David S; Halleran, Devin R; Helmrath, Michael A; Kabre, Rashmi; Knezevich, Michelle S; Lal, Dave R; Landman, Matthew P; Lawrence, Amy E; Mak, Grace Z; Minneci, Peter C; Musili, Ninette; Rymeski, Beth; Saito, Jacqueline M; Sato, Thomas T; St Peter, Shawn D; Warner, Brad W; Ostlie, Daniel J 2020. Changing the Paradigm for Management of Pediatric Primary Spontaneous Pneumothorax: A Simple Aspiration Test Predicts Need for Operation. Journal of pediatric surgery, 55 1, 169-175McCauley, Heather A; Matthis, Andrea L; Enriquez, Jacob R; Nichol, Jonah T; Sanchez, J Guillermo; Stone, William J; Sundaram, Nambirajan; Helmrath, Michael A; Montrose, Marshall H; Aihara, Eitaro; Wells, James M 2020. Enteroendocrine cells couple nutrient sensing to nutrient absorption by regulating ion transport. Nature communications, 11 1, 4791Minneci, Peter C; Hade, Erinn M; Lawrence, Amy E; Sebastião, Yuri V; Saito, Jacqueline M; Mak, Grace Z; Fox, Christa; Hirschl, Ronald B; Gadepalli, Samir; Helmrath, Michael A; Kohler, Jonathan E; Leys, Charles M; Sato, Thomas T; Lal, Dave R; Landman, Matthew P; Kabre, Rashmi; Fallat, Mary E; Cooper, Jennifer N; Deans, Katherine J 2020. Association of Nonoperative Management Using Antibiotic Therapy vs Laparoscopic Appendectomy With Treatment Success and Disability Days in Children With Uncomplicated Appendicitis. JAMA, 324 6, 581-593Pradhan, Suman; Karve, Sayali S; Weiss, Alison A; Hawkins, Jennifer; Poling, Holly M; Helmrath, Michael A; Wells, James M; McCauley, Heather A 2020. Tissue Responses to Shiga Toxin in Human Intestinal Organoids. Cellular and molecular gastroenterology and hepatology, 10 1, 171-190Shah, Amy S; Nadeau, Kristen J; Helmrath, Michael A; Inge, Thomas H; Xanthakos, Stavra A; Kelsey, Megan M 2020. Metabolic outcomes of surgery in youth with type 2 diabetes. Seminars in pediatric surgery, 29 1, 150893Singh, Akaljot; Poling, Holly M; Spence, Jason R; Wells, James M; Helmrath, Michael A 2020. Gastrointestinal organoids: a next-generation tool for modeling human development. American journal of physiology. Gastrointestinal and liver physiology, 319 3, G375-G381Singh, Akaljot; Poling, Holly M; Sundaram, Nambirajan; Brown, Nicole; Wells, James M; Helmrath, Michael A 2020. Evaluation of transplantation sites for human intestinal organoids. PloS one, 15 8, e0237885Sitzman, Thomas J; Carle, Adam C; Lundberg, Jaclyn N; Heaton, Pamela C; Helmrath, Michael A; Trotman, Carroll-Ann; Britto, Maria T 2020. Marked Variation Exists Among Surgeons and Hospitals in the Use of Secondary Cleft Lip Surgery. The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 57 2, 198-207Vales, Simon; Poling, Holly M; Sundaram, Nambirajan; Helmrath, Michael A; Mahe, Maxime M 2020. In Vivo Human PSC-Derived Intestinal Organoids to Study Stem Cell Maintenance. Methods in molecular biology (Clifton, N.J.), 2171 , 201-214Valvi, Damaskini; Walker, Douglas I; Inge, Thomas; Bartell, Scott M; Jenkins, Todd; Helmrath, Michael; Ziegler, Thomas R; La Merrill, Michele A; Eckel, Sandrah P; Conti, David; Liang, Yongliang; Jones, Dean P; McConnell, Rob; Chatzi, Leda 2020. Environmental chemical burden in metabolic tissues and systemic biological pathways in adolescent bariatric surgery patients: A pilot untargeted metabolomic approach. Environment international, 143 , 105957Xanthakos, Stavra A; Khoury, Jane C; Inge, Thomas H; Jenkins, Todd M; Modi, Avani C; Michalsky, Marc P; Chen, Mike K; Courcoulas, Anita P; Harmon, Carroll M; Brandt, Mary L; Helmrath, Michael A; Kalkwarf, Heidi J 2020. Nutritional Risks in Adolescents After Bariatric Surgery. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 18 5, 1070-1081.e5Bout-Tabaku, Sharon; Gupta, Resmi; Jenkins, Todd M; Ryder, Justin R; Baughcum, Amy E; Jackson, Rebecca D; Inge, Thomas H; Dixon, John B; Helmrath, Michael A; Courcoulas, Anita P; Mitchell, James E; Harmon, Carroll M; Xie, Changchun; Michalsky, Marc P 2019. Musculoskeletal Pain, Physical Function, and Quality of Life After Bariatric Surgery. Pediatrics, 144 6, Capeling, Meghan M; Czerwinski, Michael; Huang, Sha; Tsai, Yu-Hwai; Wu, Angeline; Nagy, Melinda S; Juliar, Benjamin; Sundaram, Nambirajan; Song, Yang; Han, Woojin M; Takayama, Shuichi; Alsberg, Eben; Garcia, Andres J; Helmrath, Michael; Putnam, Andrew J; Spence, Jason R 2019. Nonadhesive Alginate Hydrogels Support Growth of Pluripotent Stem Cell-Derived Intestinal Organoids. Stem cell reports, 12 2, 381-394Capurro, Mariana I; Greenfield, Laura K; Prashar, Akriti; Xia, Sunny; Abdullah, Majd; Wong, Harikesh; Zhong, Xi Zoe; Bertaux-Skeirik, Nina; Chakrabarti, Jayati; Siddiqui, Iram; O'Brien, Catherine; Dong, Xianping; Robinson, Lisa; Peek, Richard M; Philpott, Dana J; Zavros, Yana; Helmrath, Michael; Jones, Nicola L 2019. VacA generates a protective intracellular reservoir for Helicobacter pylori that is eliminated by activation of the lysosomal calcium channel TRPML1. Nature microbiology, 4 8, 1411-1423Goddard, Gillian R; Kotagal, Meera; Jenkins, Todd M; Kollar, Linda M; Inge, Thomas H; Helmrath, Michael A 2019. Weight loss after sleeve gastrectomy in developmentally delayed adolescents and young adults. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 15 10, 1662-1667Holokai, Loryn; Chakrabarti, Jayati; Broda, Taylor; Chang, Julie; Hawkins, Jennifer A; Sundaram, Nambirajan; Wroblewski, Lydia E; Peek, Richard M; Wang, Jiang; Helmrath, Michael; Wells, James M; Zavros, Yana 2019. Increased Programmed Death-Ligand 1 is an Early Epithelial Cell Response to Helicobacter pylori Infection. PLoS pathogens, 15 1, e1007468Inge, Thomas H; Courcoulas, Anita P; Helmrath, Michael A 2019. Five-Year Outcomes of Gastric Bypass in Adolescents as Compared with Adults. Reply. The New England journal of medicine, 381 9, e17Inge, Thomas H; Courcoulas, Anita P; Jenkins, Todd M; Michalsky, Marc P; Brandt, Mary L; Xanthakos, Stavra A; Dixon, John B; Harmon, Carroll M; Chen, Mike K; Xie, Changchun; Evans, Mary E; Helmrath, Michael A 2019. Five-Year Outcomes of Gastric Bypass in Adolescents as Compared with Adults. The New England journal of medicine, 380 22, 2136-2145Kunisaki, Shaun M; Saito, Jacqueline M; Fallat, Mary E; St Peter, Shawn D; Kim, Aimee G; Johnson, Kevin N; Mon, Rodrigo A; Adams, Cheryl; Aladegbami, Bola; Bence, Christina; Burns, R Cartland; Corkum, Kristine S; Deans, Katherine J; Downard, Cynthia D; Fraser, Jason D; Gadepalli, Samir K; Helmrath, Michael A; Kabre, Rashmi; Lal, Dave R; Landman, Matthew P; Leys, Charles M; Linden, Allison F; Lopez, Joseph J; Mak, Grace Z; Minneci, Peter C; Rademacher, Brooks L; Shaaban, Aimen; Walker, Sarah K; Wright, Tiffany N; Hirschl, Ronald B 2019. Current operative management of congenital lobar emphysema in children: A report from the Midwest Pediatric Surgery Consortium. Journal of pediatric surgery, 54 6, 1138-1142Lal, Dave R; Gadepalli, Samir K; Downard, Cynthia D; Minneci, Peter C; Knezevich, Michelle; Chelius, Thomas H; Rapp, Cooper T; Billmire, Deborah; Bruch, Steven; Carland Burns, R; Deans, Katherine J; Fallat, Mary E; Fraser, Jason D; Grabowski, Julia; Hebel, Ferdynand; Helmrath, Michael A; Hirschl, Ronald B; Kabre, Rashmi; Kohler, Jonathan; Landman, Matthew P; Leys, Charles M; Mak, Grace Z; Ostlie, Daniel J; Raque, Jessica; Rymeski, Beth; Saito, Jacqueline M; St Peter, Shawn D; von Allmen, Daniel; Warner, Brad W; Sato, Thomas T 2019. Infants with esophageal atresia and right aortic arch: Characteristics and outcomes from the Midwest Pediatric Surgery Consortium. Journal of pediatric surgery, 54 4, 688-692Minneci, Peter C; Hade, Erinn M; Lawrence, Amy E; Saito, Jacqueline M; Mak, Grace Z; Hirschl, Ronald B; Gadepalli, Samir; Helmrath, Michael A; Leys, Charles M; Sato, Thomas T; Lal, Dave R; Landman, Matthew P; Kabre, Rashmi; Fallat, Mary E; Fischer, Beth A; Cooper, Jennifer N; Deans, Katherine J 2019. Multi-institutional trial of non-operative management and surgery for uncomplicated appendicitis in children: Design and rationale. Contemporary clinical trials, 83 , 10-17Minneci, Peter C; Kabre, Rashmi S; Mak, Grace Z; Halleran, Devin R; Cooper, Jennifer N; Afrazi, Amin; Calkins, Casey M; Corkum, Kristine; Downard, Cynthia D; Ehrlich, Peter; Fraser, Jason D; Gadepalli, Samir K; Helmrath, Michael A; Kohler, Jonathan E; Landisch, Rachel; Landman, Matthew P; Lee, Constance; Leys, Charles M; Lodwick, Daniel L; McLeod, Jennifer; Mon, Rodrigo; McClure, Beth; Rymeski, Beth; Saito, Jacqueline M; Sato, Thomas T; St Peter, Shawn D; Wood, Richard; Levitt, Marc A; Deans, Katherine J 2019. Can fecal continence be predicted in patients born with anorectal malformations? Journal of pediatric surgery, 54 6, 1159-1163Múnera, Jorge O; Sundaram, Nambirajan; Rankin, Scott A; Hill, David; Watson, Carey; Mahe, Maxime; Vallance, Jefferson E; Shroyer, Noah F; Sinagoga, Katie L; Zarzoso-Lacoste, Adrian; Hudson, Jonathan R; Howell, Jonathan C; Chatuvedi, Praneet; Spence, Jason R; Shannon, John M; Zorn, Aaron M; Helmrath, Michael A; Wells, James M 2019. Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling. Cell stem cell, 24 5, 829Noah, Taeko K; Knoop, Kathryn A; McDonald, Keely G; Gustafsson, Jenny K; Waggoner, Lisa; Vanoni, Simone; Batie, Matthew; Arora, Kavisha; Naren, Anjaparavanda P; Wang, Yui-Hsi; Lukacs, Nicholas W; Munitz, Ariel; Helmrath, Michael A; Mahe, Maxime M; Newberry, Rodney D; Hogan, Simon P 2019. IL-13-induced intestinal secretory epithelial cell antigen passages are required for IgE-mediated food-induced anaphylaxis. The Journal of allergy and clinical immunology, 144 4, 1058-1073.e3Sitzman, Thomas J; Carle, Adam C; Heaton, Pamela C; Helmrath, Michael A; Britto, Maria T 2019. Five-Fold Variation Among Surgeons and Hospitals in the Use of Secondary Palate Surgery. The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 56 5, 586-594Steele, Nina G; Chakrabarti, Jayati; Wang, Jiang; Biesiada, Jacek; Holokai, Loryn; Chang, Julie; Nowacki, Lauren M; Hawkins, Jennifer; Mahe, Maxime; Sundaram, Nambirajan; Shroyer, Noah; Medvedovic, Mario; Helmrath, Michael; Ahmad, Syed; Zavros, Yana 2019. An Organoid-Based Preclinical Model of Human Gastric Cancer. Cellular and molecular gastroenterology and hepatology, 7 1, 161-184Brode, Cassie; Ratcliff, Megan; Reiter-Purtill, Jennifer; Hunsaker, Sanita; Helmrath, Michael; Zeller, Meg 2018. Predictors of Preoperative Program Non-Completion in Adolescents Referred for Bariatric Surgery. Obesity surgery, 28 9, 2853-2859Cortez, Alexander R; Poling, Holly M; Brown, Nicole E; Singh, Akaljot; Mahe, Maxime M; Helmrath, Michael A 2018. Transplantation of human intestinal organoids into the mouse mesentery: A more physiologic and anatomic engraftment site. Surgery, 164 4, 643-650Cushing, Christopher C; Threlkeld, Melody R S; Martinez-Leo, Bruno; Hall, Jennifer; Hossain, Monir; Dickie, Belinda H; Rymeski, Beth; Helmrath, Michael; Zeller, Meg H; Frischer, Jason S 2018. Initial development and validation of a fecal incontinence-specific quality of life measure. Journal of pediatric surgery, 53 6, 1148-1153Kelly, Daniel; Kotliar, Michael; Woo, Vivienne; Jagannathan, Sajjeev; Whitt, Jordan; Moncivaiz, Jessica; Aronow, Bruce J; Dubinsky, Marla C; Hyams, Jeffrey S; Markowitz, James F; Baldassano, Robert N; Stephens, Michael C; Walters, Thomas D; Kugathasan, Subra; Haberman, Yael; Sundaram, Nambirajan; Rosen, Michael J; Helmrath, Michael; Karns, Rebekah; Barski, Artem; Denson, Lee A; Alenghat, Theresa 2018. Microbiota-sensitive epigenetic signature predicts inflammation in Crohn's disease. JCI insight, 3 18, Lal, Dave R; Gadepalli, Samir K; Downard, Cynthia D; Ostlie, Daniel J; Minneci, Peter C; Swedler, Ruth M; Chelius, Thomas H; Cassidy, Laura; Rapp, Cooper T; Billmire, Deborah; Bruch, Steven; Burns, R Carland; Deans, Katherine J; Fallat, Mary E; Fraser, Jason D; Grabowski, Julia; Hebel, Ferdynand; Helmrath, Michael A; Hirschl, Ronald B; Kabre, Rashmi; Kohler, Jonathan; Landman, Matthew P; Leys, Charles M; Mak, Grace Z; Raque, Jessica; Rymeski, Beth; Saito, Jacqueline M; St Peter, Shawn D; von Allmen, Daniel; Warner, Brad W; Sato, Thomas T 2018. Challenging surgical dogma in the management of proximal esophageal atresia with distal tracheoesophageal fistula: Outcomes from the Midwest Pediatric Surgery Consortium. Journal of pediatric surgery, 53 7, 1267-1272Marchix, Justine; Goddard, Gillian; Helmrath, Michael A 2018. Host-Gut Microbiota Crosstalk in Intestinal Adaptation. Cellular and molecular gastroenterology and hepatology, 6 2, 149-162Michalsky, Marc P; Inge, Thomas H; Jenkins, Todd M; Xie, Changchun; Courcoulas, Anita; Helmrath, Michael; Brandt, Mary L; Harmon, Carroll M; Chen, Mike; Dixon, John B; Urbina, Elaine M 2018. Cardiovascular Risk Factors After Adolescent Bariatric Surgery. Pediatrics, 141 2, Minneci, Peter C; Kabre, Rashmi S; Mak, Grace Z; Halleran, Devin R; Cooper, Jennifer N; Afrazi, Amin; Calkins, Casey M; Downard, Cynthia D; Ehrlich, Peter; Fraser, Jason; Gadepalli, Samir K; Helmrath, Michael A; Kohler, Jonathan E; Landisch, Rachel; Landman, Matthew P; Lee, Constance; Leys, Charles M; Lodwick, Daniel L; Mon, Rodrigo; McClure, Beth; Rymeski, Beth; Saito, Jacqueline M; Sato, Thomas T; St Peter, Shawn D; Wood, Richard; Levitt, Marc A; Deans, Katherine J 2018. Screening practices and associated anomalies in infants with anorectal malformations: Results from the Midwest Pediatric Surgery Consortium. Journal of pediatric surgery, 53 6, 1163-1167Poling, Holly M; Wu, David; Brown, Nicole; Baker, Michael; Hausfeld, Taylor A; Huynh, Nhan; Chaffron, Samuel; Dunn, James C Y; Hogan, Simon P; Wells, James M; Helmrath, Michael A; Mahe, Maxime M 2018. Mechanically induced development and maturation of human intestinal organoids in vivo. Nature biomedical engineering, 2 6, 429-442Sinagoga, Katie L; McCauley, Heather A; Múnera, Jorge O; Reynolds, Nichole A; Enriquez, Jacob R; Watson, Carey; Yang, Hsiu-Chiung; Helmrath, Michael A; Wells, James M 2018. Deriving functional human enteroendocrine cells from pluripotent stem cells. Development (Cambridge, England), 145 19, Takebe, Takanori; Wells, James M; Helmrath, Michael A; Zorn, Aaron M 2018. Organoid Center Strategies for Accelerating Clinical Translation. Cell stem cell, 22 6, 806-809Asai, Akihiro; Aihara, Eitaro; Watson, Carey; Mourya, Reena; Mizuochi, Tatsuki; Shivakumar, Pranavkumar; Phelan, Kieran; Mayhew, Christopher; Helmrath, Michael; Takebe, Takanori; Wells, James; Bezerra, Jorge A 2017. Paracrine signals regulate human liver organoid maturation from induced pluripotent stem cells. Development (Cambridge, England), 144 6, 1056-1064Bertaux-Skeirik, Nina; Wunderlich, Mark; Teal, Emma; Chakrabarti, Jayati; Biesiada, Jacek; Mahe, Maxime; Sundaram, Nambirajan; Gabre, Joel; Hawkins, Jennifer; Gao, Jian; Engevik, Amy C; Yang, Li; Wang, Jiang; Goldenring, James R; Qualls, Joseph E; Medvedovic, Mario; Helmrath, Michael A; Diwan, Tayyab; Mulloy, James C; Zavros, Yana 2017. CD44 variant isoform 9 emerges in response to injury and contributes to the regeneration of the gastric epithelium. The Journal of pathology, , Inge, Thomas H; Jenkins, Todd M; Xanthakos, Stavra A; Dixon, John B; Daniels, Stephen R; Zeller, Meg H; Helmrath, Michael A 2017. Long-term outcomes of bariatric surgery in adolescents with severe obesity (FABS-5+): a prospective follow-up analysis. The lancet. Diabetes & endocrinology, 5 3, 165-173Mahe, Maxime M; Brown, Nicole E; Poling, Holly M; Helmrath, Michael A 2017. Erratum to: In Vivo Model of Small Intestine. Methods in molecular biology (Clifton, N.J.), 1597 , E1Maxime, Mahe M; Brown, Nicole E; Poling, Holly M; Michael, Helmrath A 2017. In Vivo Model of Small Intestine. Methods in molecular biology (Clifton, N.J.), 1597 , 229-245Múnera, Jorge O; Sundaram, Nambirajan; Rankin, Scott A; Hill, David; Watson, Carey; Mahe, Maxime; Vallance, Jefferson E; Shroyer, Noah F; Sinagoga, Katie L; Zarzoso-Lacoste, Adrian; Hudson, Jonathan R; Howell, Jonathan C; Chatuvedi, Praneet; Spence, Jason R; Shannon, John M; Zorn, Aaron M; Helmrath, Michael A; Wells, James M 2017. Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling. Cell stem cell, 21 1, 51-64.e6Nalapareddy, Kodandaramireddy; Nattamai, Kalpana J; Kumar, Rupali S; Karns, Rebekah; Wikenheiser-Brokamp, Kathryn A; Sampson, Leesa L; Mahe, Maxime M; Sundaram, Nambirajan; Yacyshyn, Mary-Beth; Yacyshyn, Bruce; Helmrath, Michael A; Zheng, Yi; Geiger, Hartmut 2017. Canonical Wnt Signaling Ameliorates Aging of Intestinal Stem Cells. Cell reports, 18 11, 2608-2621Sarwer, David B; Dilks, Rebecca J; Spitzer, Jacqueline C; Berkowitz, Robert I; Wadden, Thomas A; Moore, Renee H; Chittams, Jesse L; Brandt, Mary L; Chen, Mike K; Courcoulas, Anita P; Harmon, Carroll M; Helmrath, Michael A; Michalsky, Marc P; Xanthakos, Stavra A; Zeller, Meg H; Jenkins, Todd M; Inge, Thomas H 2017. Changes in Dietary Intake and Eating Behavior in Adolescents After Bariatric Surgery: an Ancillary Study to the Teen-LABS Consortium. Obesity surgery, 27 12, 3082-3091Wessel, Jacqueline; Kotagal, Meera; Helmrath, Michael A 2017. Management of Pediatric Intestinal Failure. Advances in pediatrics, 64 1, 253-267Workman, Michael J; Mahe, Maxime M; Trisno, Stephen; Poling, Holly M; Watson, Carey L; Sundaram, Nambirajan; Chang, Ching-Fang; Schiesser, Jacqueline; Aubert, Philippe; Stanley, Edouard G; Elefanty, Andrew G; Miyaoka, Yuichiro; Mandegar, Mohammad A; Conklin, Bruce R; Neunlist, Michel; Brugmann, Samantha A; Helmrath, Michael A; Wells, James M 2017. Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system. Nature medicine, 23 1, 49-59Zeller, Meg H; Pendery, Emma C; Reiter-Purtill, Jennifer; Hunsaker, Sanita L; Jenkins, Todd M; Helmrath, Michael A; Inge, Thomas H 2017. From adolescence to young adulthood: trajectories of psychosocial health following Roux-en-Y gastric bypass. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, , Cohran, Valeria; Managlia, Elizabeth; Bradford, Emily M; Goretsky, Tatiana; Li, Ting; Katzman, Rebecca B; Cheresh, Paul; Brown, Jeffrey B; Hawkins, Jennifer; Liu, Shirley X L; De Plaen, Isabelle G; Weitkamp, Jörn-Hendrik; Helmrath, Michael; Zhang, Zheng; Barrett, Terrence A 2016. Epithelial PIK3R1 (p85) and TP53 Regulate Survivin Expression during Adaptation to Ileocecal Resection. The American journal of pathology, 186 7, 1837-46Cushing, Christopher C; Martinez-Leo, Bruno; Bischoff, Andrea; Hall, Jennifer; Helmrath, Michael; Dickie, Belinda H; Levitt, Marc A; Peña, Alberto; Zeller, Meg H; Frischer, Jason S 2016. Health-Related Quality of Life and Parental Stress in Children With Fecal Incontinence: A Normative Comparison. Journal of pediatric gastroenterology and nutrition, 63 6, 633-636Engevik, Amy C; Feng, Rui; Choi, Eunyoung; White, Shana; Bertaux-Skeirik, Nina; Li, Jing; Mahe, Maxime M; Aihara, Eitaro; Yang, Li; DiPasquale, Betsy; Oh, Sunghee; Engevik, Kristen A; Giraud, Andrew S; Montrose, Marshall H; Medvedovic, Mario; Helmrath, Michael A; Goldenring, James R; Zavros, Yana 2016. The Development of Spasmolytic Polypeptide/TFF2-Expressing Metaplasia (SPEM) During Gastric Repair Is Absent in the Aged Stomach. Cellular and molecular gastroenterology and hepatology, 2 5, 605-624Hirschl, Ronald B; Minneci, Peter; Gadepalli, Samir; Saito, Jacqueline M; Askegard-Giesmann, Johanna; Deans, Katherine; Downard, Cynthia; Fallat, Mary; Finnell, Maria; Helmrath, Michael; Kabre, Rashmi; Lal, David; Leys, Charles; Mak, Grace; Ostlie, Daniel; Rescorla, Fred; Sato, Thomas; St Peter, Shawn; von Allmen, Daniel; Warner, Brad 2016. Development of a multi-institutional clinical research consortium for pediatric surgery. Journal of pediatric surgery, , Inge, Thomas H; Courcoulas, Anita P; Jenkins, Todd M; Michalsky, Marc P; Helmrath, Michael A; Brandt, Mary L; Harmon, Carroll M; Zeller, Meg H; Chen, Mike K; Xanthakos, Stavra A; Horlick, Mary; Buncher, C Ralph 2016. Weight Loss and Health Status 3 Years after Bariatric Surgery in Adolescents. The New England journal of medicine, 374 2, 113-23Lal, Dave R; Gadepalli, Samir K; Downard, Cynthia D; Ostlie, Daniel J; Minneci, Peter C; Swedler, Ruth M; Chelius, Thomas; Cassidy, Laura; Rapp, Cooper T; Deans, Katherine J; Fallat, Mary E; Finnell, S Maria E; Helmrath, Michael A; Hirschl, Ronald B; Kabre, Rashmi S; Leys, Charles M; Mak, Grace; Raque, Jessica; Rescorla, Frederick J; Saito, Jacqueline M; St Peter, Shawn D; von Allmen, Daniel; Warner, Brad W; Sato, Thomas T 2016. Perioperative management and outcomes of esophageal atresia and tracheoesophageal fistula. Journal of pediatric surgery, , Mezoff, Ethan A; Hawkins, Jennifer A; Ollberding, Nicholas J; Karns, Rebekah; Morrow, Ardythe L; Helmrath, Michael A 2016. The human milk oligosaccharide 2'-fucosyllactose augments the adaptive response to extensive intestinal. American journal of physiology. Gastrointestinal and liver physiology, 310 6, G427-38Aihara, Eitaro; Mahe, Maxime M; Schumacher, Michael A; Matthis, Andrea L; Feng, Rui; Ren, Wenwen; Noah, Taeko K; Matsu-ura, Toru; Moore, Sean R; Hong, Christian I; Zavros, Yana; Herness, Scott; Shroyer, Noah F; Iwatsuki, Ken; Jiang, Peihua; Helmrath, Michael A; Montrose, Marshall H 2015. Characterization of stem/progenitor cell cycle using murine circumvallate papilla taste bud organoid. Scientific reports, 5 , 17185Bout-Tabaku, Sharon; Michalsky, Marc P; Jenkins, Todd M; Baughcum, Amy; Zeller, Meg H; Brandt, Mary L; Courcoulas, Anita; Buncher, Ralph; Helmrath, Michael; Harmon, Carroll M; Chen, Mike K; Inge, Thomas H 2015. Musculoskeletal Pain, Self-reported Physical Function, and Quality of Life in the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) Cohort. JAMA pediatrics, 169 6, 552-9Michalsky, Marc P; Inge, Thomas H; Simmons, Mark; Jenkins, Todd M; Buncher, Ralph; Helmrath, Michael; Brandt, Mary L; Harmon, Carroll M; Courcoulas, Anita; Chen, Michael; Horlick, Mary; Daniels, Stephen R; Urbina, Elaine M 2015. Cardiovascular Risk Factors in Severely Obese Adolescents: The Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) Study. JAMA pediatrics, 169 5, 438-44Moon, Changsuk; Zhang, Weiqiang; Sundaram, Nambirajan; Yarlagadda, Sunitha; Reddy, Vadde Sudhakar; Arora, Kavisha; Helmrath, Michael A; Naren, Anjaparavanda P 2015. Drug-induced secretory diarrhea: A role for CFTR. Pharmacological research, 102 , 107-12Xanthakos, Stavra A; Jenkins, Todd M; Kleiner, David E; Boyce, Tawny W; Mourya, Reena; Karns, Rebekah; Brandt, Mary L; Harmon, Carroll M; Helmrath, Michael A; Michalsky, Marc P; Courcoulas, Anita P; Zeller, Meg H; Inge, Thomas H 2015. High Prevalence of Nonalcoholic Fatty Liver Disease in Adolescents Undergoing Bariatric Surgery. Gastroenterology, , Zeller, Meg H; Inge, Thomas H; Modi, Avani C; Jenkins, Todd M; Michalsky, Marc P; Helmrath, Michael; Courcoulas, Anita; Harmon, Carroll M; Rofey, Dana; Baughcum, Amy; Austin, Heather; Price, Karin; Xanthakos, Stavra A; Brandt, Mary L; Horlick, Mary; Buncher, Ralph 2015. Severe obesity and comorbid condition impact on the weight-related quality of life of the adolescent patient. The Journal of pediatrics, 166 3, 651-9.e4Inge, Thomas H; Boyce, Tawny W; Lee, Margaret; Kollar, Linda; Jenkins, Todd M; Brandt, Mary L; Helmrath, Michael; Xanthakos, Stavra A; Zeller, Meg H; Harmon, Carroll M; Courcoulas, Anita; Michalsky, Marc P 2014. Access to care for adolescents seeking weight loss surgery. Obesity (Silver Spring, Md.), 22 12, 2593-7Inge, Thomas H; Zeller, Meg H; Jenkins, Todd M; Helmrath, Michael; Brandt, Mary L; Michalsky, Marc P; Harmon, Carroll M; Courcoulas, Anita; Horlick, Mary; Xanthakos, Stavra A; Dolan, Larry; Mitsnefes, Mark; Barnett, Sean J; Buncher, Ralph 2014. Perioperative outcomes of adolescents undergoing bariatric surgery: the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study. JAMA pediatrics, 168 1, 47-53Michalsky, Marc P; Inge, Thomas H; Teich, Steven; Eneli, Ihuoma; Miller, Rosemary; Brandt, Mary L; Helmrath, Michael; Harmon, Carroll M; Zeller, Meg H; Jenkins, Todd M; Courcoulas, Anita; Buncher, Ralph C 2014. Adolescent bariatric surgery program characteristics: the Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study experience. Seminars in pediatric surgery, 23 1, 5-10Xiao, Nianzhou; Jenkins, Todd M; Nehus, Edward; Inge, Thomas H; Michalsky, Marc P; Harmon, Carroll M; Helmrath, Michael A; Brandt, Mary L; Courcoulas, Anita; Moxey-Mims, Marva; Mitsnefes, Mark M 2014. Kidney function in severely obese adolescents undergoing bariatric surgery. Obesity (Silver Spring, Md.), 22 11, 2319-25Eradi, Balgopal; Hamrick, Miller; Bischoff, Andrea; Frischer, Jason S; Helmrath, Michael; Hall, Jennifer; Peña, Alberto; Levitt, Marc A 2013. The role of a colon resection in combination with a Malone appendicostomy as part of a bowel management program for the treatment of fecal incontinence. Journal of pediatric surgery, 48 11, 2296-300Ubesie, Agozie C; Kocoshis, Samuel A; Mezoff, Adam G; Henderson, Carol J; Helmrath, Michael A; Cole, Conrad R 2013. Multiple micronutrient deficiencies among patients with intestinal failure during and after transition to enteral nutrition. The Journal of pediatrics, 163 6, 1692-6Dehmer, Jeffrey J; Fuller, Megan K; Helmrath, Michael A 2011. Management of pediatric intestinal failure. Advances in pediatrics, 58 1, 181-94Hamrick, Miller; Helmrath, Michael; Bischoff, Andrea; Eradi, Balgopal; Levitt, Marc; Peña, Alberto 2011. Letter to the Editor regarding comparison of anorectal angle and continence after Georgeson and Peña procedures for high/intermediate imperforate anus. Journal of pediatric surgery, 46 5, 1019-20; author replBrandt, Mary L; Harmon, Carroll M; Helmrath, Michael A; Inge, Thomas H; McKay, Siripoom V; Michalsky, Marc P 2010. Morbid obesity in pediatric diabetes mellitus: surgical options and outcomes. Nature reviews. Endocrinology, 6 11, 637-45Inge, Thomas; Helmrath, Michael; Vierra, Mark 2010. The Santoro III massive enterectomy: how can we justify the risks in obese adolescents? Obesity surgery, 20 12, 1718-9Garrison, Aaron P; Helmrath, Michael A; Dekaney, Christopher M 2009. Intestinal stem cells. Journal of pediatric gastroenterology and nutrition, 49 1, 2-7Inge, Thomas H; Miyano, Go; Bean, Judy; Helmrath, Michael; Courcoulas, Anita; Harmon, Carroll M; Chen, Mike K; Wilson, Kimberly; Daniels, Stephen R; Garcia, Victor F; Brandt, Mary L; Dolan, Lawrence M 2009. Reversal of type 2 diabetes mellitus and improvements in cardiovascular risk factors after surgical weight loss in adolescents. Pediatrics, 123 1, 214-22Inge, Thomas; Helmrath, Michael; Vierra, Mark; Ikramuddin, Sayeed 2008. Challenges of adolescent bariatric surgery: tips for managing the extremely obese teen. Journal of laparoendoscopic & advanced surgical techniques. Part A, 18 1, 157-69De Silva, Nirupama K; Helmrath, Michael A; Klish, William J 2007. Obesity in the adolescent female. Journal of pediatric and adolescent gynecology, 20 3, 207-13Fuller, Megan K; Helmrath, Michael A 2007. Thoracic empyema, application of video-assisted thoracic surgery and its current management. Current opinion in pediatrics, 19 3, 328-32Inge, Thomas H; Zeller, Meg; Harmon, Carroll; Helmrath, Michael; Bean, Judy; Modi, Avani; Horlick, Mary; Kalra, Maninder; Xanthakos, Stavra; Miller, Rosemary; Akers, Rachel; Courcoulas, Anita 2007. Teen-Longitudinal Assessment of Bariatric Surgery: methodological features of the first prospective multicenter study of adolescent bariatric surgery. Journal of pediatric surgery, 42 11, 1969-71Helmrath, Michael A; Brandt, Mary L; Inge, Thomas H 2006. Adolescent obesity and bariatric surgery. The Surgical clinics of North America, 86 2, 441-54, xKenton, Alexander B; Hegemier, Suzanne; Smith, E O'Brian; O'Donovan, Donough J; Brandt, Mary L; Cass, Darrell L; Helmrath, Michael A; Washburn, Kimberly; Weihe, Elizabeth K; Fernandes, Caraciolo J 2005. Platelet transfusions in infants with necrotizing enterocolitis do not lower mortality but may increase morbidity. Journal of perinatology : official journal of the California Perinatal Association, 25 3, 173-7Kenton, Alexander B; O'Donovan, Donough; Cass, Darrell L; Helmrath, Michael A; Smith, E O'brian; Fernandes, Caraciolo J; Washburn, Kimberly; Weihe, Elizabeth K; Brandt, Mary L 2005. Severe thrombocytopenia predicts outcome in neonates with necrotizing enterocolitis. Journal of perinatology : official journal of the California Perinatal Association, 25 1, 14-20Inge, Thomas H; Krebs, Nancy F; Garcia, Victor F; Skelton, Joseph A; Guice, Karen S; Strauss, Richard S; Albanese, Craig T; Brandt, Mary L; Hammer, Lawrence D; Harmon, Carol M; Kane, Timothy D; Klish, William J; Oldham, Keith T; Rudolph, Colin D; Helmrath, Michael A; Donovan, Edward; Daniels, Stephen R 2004. Bariatric surgery for severely overweight adolescents: concerns and recommendations. Pediatrics, 114 1, 217-23Klish, William J; Brandt, Mary L; Helmrath, Michael A 2004. Obesity surgery in pediatrics. Journal of pediatric gastroenterology and nutrition, 39 1, 2-4