Education/CredentialsPhD: Southern Medical University Contact Information Health UC - Georgetown Office 513-584-7284 Email liangjl@ucmail.uc.edu Peer Reviewed Publications He, Xingyu; Dutta, Suchandrima; Liang, Jialiang; Paul, Christian; Huang, Wei; Xu, Meifeng; Chang, Vivian; Wang, Yigang 2023. Direct Cellular Reprogramming Techniques for Cardiovascular Regenerative Therapeutics. Canadian journal of physiology and pharmacology, , Park, Ki Ho; He, Xingyu; Jiang, Lin; Zhu, Hua; Liang, Jialiang; Wang, Yigang; Ma, Jianjie 2023. Activation of MG53 Enhances Cell Survival and Engraftment of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Injured Hearts. Stem cell reviews and reports, 19 7, 2420-2428Wu, Zhichao; Huang, Wei; He, Xingyu; Dutta, Suchandrima; Paul, Christian; Fan, Guo-Chang; Kanisicak, Onur; Xu, Meifeng; Liang, Jialiang; Wang, Yigang 2023. Myocardial IGF2R is a critical mediator of inflammation and fibrosis after ischemia-reperfusion injury. bioRxiv : the preprint server for biology, , He, Xingyu; Liang, Jialiang; Paul, Christian; Huang, Wei; Dutta, Suchandrima; Wang, Yigang 2022. Advances in Cellular Reprogramming-Based Approaches for Heart Regenerative Repair. Cells, 11 23, Jiang, Lin; Liang, Jialiang; Huang, Wei; Ma, Jianyong; Park, Ki Ho; Wu, Zhichao; Chen, Peng; Zhu, Hua; Ma, Jian-Jie; Cai, Wenfeng; Paul, Christian; Niu, Liang; Fan, Guo-Chang; Wang, Hong-Sheng; Kanisicak, Onur; Xu, Meifeng; Wang, Yigang 2022. CRISPR activation of endogenous genes reprograms fibroblasts into cardiovascular progenitor cells for myocardial infarction therapy. Molecular therapy : the journal of the American Society of Gene Therapy, 30 1, 54-74Wu, Zhichao; Liang, Jialiang; Huang, Wei; Jiang, Lin; Paul, Christian; Gao, Xiang; Alam, Perwez; Kanisicak, Onur; Xu, Meifeng; Wang, Yigang 2021. Immunomodulatory effects of mesenchymal stem cells for the treatment of cardiac allograft rejection. Experimental biology and medicine (Maywood, N.J.), 246 7, 851-860Wu, Zhichao; Liang, Jialiang; Huang, Wei; Jiang, Lin; Paul, Christian; Lin, Bonnie; Zheng, Junmeng; Wang, Yigang 2021. Prompt Graft Cooling Enhances Cardioprotection during Heart Transplantation Procedures through the Regulation of Mitophagy. Cells, 10 11, Jiang, Lin; Liang, Jialiang; Huang, Wei; Wu, Zhichao; Paul, Christian; Wang, Yigang 2020. Strategies and Challenges to Improve Cellular Programming-Based Approaches for Heart Regeneration Therapy. International journal of molecular sciences, 21 20, Liang, Jialiang; Huang, Wei; Jiang, Lin; Paul, Christian; Li, Xiangnan; Wang, Yigang 2019. Concise Review: Reduction of Adverse Cardiac Scarring Facilitates Pluripotent Stem Cell-Based Therapy for Myocardial Infarction. Stem cells (Dayton, Ohio), 37 7, 844-854Huang, Wei; Feng, Yuliang; Liang, Jialiang; Yu, Hao; Wang, Cheng; Wang, Boyu; Wang, Mingyang; Jiang, Lin; Meng, Wei; Cai, Wenfeng; Medvedovic, Mario; Chen, Jenny; Paul, Christian; Davidson, W Sean; Sadayappan, Sakthivel; Stambrook, Peter J; Yu, Xi-Yong; Wang, Yigang 2018. Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration. Nature communications, 9 1, 700Huang, Wei; Liang, Jialiang; Feng, Yuliang; Jia, Zhanfeng; Jiang, Lin; Cai, Wenfeng; Paul, Christian; Gu, Jianguo G; Stambrook, Peter J; Millard, Ronald W; Zhu, Xiao-Lan; Zhu, Ping; Wang, Yigang 2018. Heterogeneity of adult masseter muscle satellite cells with cardiomyocyte differentiation potential. Experimental cell research, 371 1, 20-30Ma, Ruilian; Liang, Jialiang; Huang, Wei; Guo, Linlin; Cai, Wenfeng; Wang, Lei; Paul, Christian; Yang, Huang-Tian; Kim, Ha Won; Wang, Yigang 2018. Electrical Stimulation Enhances Cardiac Differentiation of Human Induced Pluripotent Stem Cells for Myocardial Infarction Therapy. Antioxidants & redox signaling, 28 5, 371-384Liang, Jialiang; Huang, Wei; Cai, Wenfeng; Wang, Lei; Guo, Linlin; Paul, Christian; Yu, Xi-Yong; Wang, Yigang 2017. Inhibition of microRNA-495 Enhances Therapeutic Angiogenesis of Human Induced Pluripotent Stem Cells. Stem cells (Dayton, Ohio), 35 2, 337-350Cai, Wen-Feng; Kang, Kai; Huang, Wei; Liang, Jia-Liang; Feng, Yu-Liang; Liu, Guan-Sheng; Chang, De-Hua; Wen, Zhi-Li; Paul, Christian; Xu, Meifeng; Millard, Ronald W; Wang, Yigang 2015. CXCR4 attenuates cardiomyocytes mitochondrial dysfunction to resist ischaemia-reperfusion injury. Journal of cellular and molecular medicine, 19 8, 1825-35Liang, Jialiang; Huang, Wei; Yu, Xiyong; Ashraf, Atif; Wary, Kishore K; Xu, Meifeng; Millard, Ronald W; Ashraf, Muhammad; Wang, Yigang 2012. Suicide gene reveals the myocardial neovascularization role of mesenchymal stem cells overexpressing CXCR4 (MSC(CXCR4)). PloS one, 7 9, e46158Yu, Xi-Yong; Geng, Yong-Jian; Liang, Jia-Liang; Zhang, Saidan; Lei, He-Ping; Zhong, Shi-Long; Lin, Qiu-Xiong; Shan, Zhi-Xin; Lin, Shu-Guang; Li, Yangxin 2012. High levels of glucose induce "metabolic memory" in cardiomyocyte via epigenetic histone H3 lysine 9 methylation. Molecular biology reports, 39 9, 8891-8Liang, Jia-Liang; Feng, Zhi-Kuan; Liu, Xiao-Ying; Lin, Qiu-Xiong; Fu, Yong-Heng; Shan, Zhi-Xin; Zhu, Jie-Ning; Lin, Shu-Guang; Yu, Xi-Yong 2011. Effect of impaired glucose tolerance on cardiac dysfunction in a rat model of prediabetes. Chinese medical journal, 124 5, 734-9Yu, Xi-Yong; Chen, Hong-Mei; Liang, Jia-Liang; Lin, Qiu-Xiong; Tan, Hong-Hong; Fu, Yong-Heng; Liu, Xiao-Ying; Shan, Zhi-Xin; Li, Xiao-Hong; Yang, Hua-Zhang; Yang, Min; Li, Yangxin; Lin, Shu-Guang 2011. Hyperglycemic myocardial damage is mediated by proinflammatory cytokine: macrophage migration inhibitory factor. PloS one, 6 1, e16239Liang, Jia-Liang; Xiao, Ding-Zhang; Liu, Xiao-Ying; Lin, Qiu-Xiong; Shan, Zhi-Xin; Zhu, Jie-Ning; Lin, Shu-Guang; Yu, Xi-Yong 2010. High glucose induces apoptosis in AC16 human cardiomyocytes via macrophage migration inhibitory factor and c-Jun N-terminal kinase. Clinical and experimental pharmacology & physiology, 37 10, 969-73Yu, Xi-Yong; Geng, Yong-Jian; Liang, Jia-Liang; Lin, Qiu-Xiong; Lin, Shu-Guang; Zhang, Saidan; Li, Yangxin 2010. High levels of glucose induce apoptosis in cardiomyocyte via epigenetic regulation of the insulin-like growth factor receptor. Experimental cell research, 316 17, 2903-9
Peer Reviewed Publications He, Xingyu; Dutta, Suchandrima; Liang, Jialiang; Paul, Christian; Huang, Wei; Xu, Meifeng; Chang, Vivian; Wang, Yigang 2023. Direct Cellular Reprogramming Techniques for Cardiovascular Regenerative Therapeutics. Canadian journal of physiology and pharmacology, , Park, Ki Ho; He, Xingyu; Jiang, Lin; Zhu, Hua; Liang, Jialiang; Wang, Yigang; Ma, Jianjie 2023. Activation of MG53 Enhances Cell Survival and Engraftment of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Injured Hearts. Stem cell reviews and reports, 19 7, 2420-2428Wu, Zhichao; Huang, Wei; He, Xingyu; Dutta, Suchandrima; Paul, Christian; Fan, Guo-Chang; Kanisicak, Onur; Xu, Meifeng; Liang, Jialiang; Wang, Yigang 2023. Myocardial IGF2R is a critical mediator of inflammation and fibrosis after ischemia-reperfusion injury. bioRxiv : the preprint server for biology, , He, Xingyu; Liang, Jialiang; Paul, Christian; Huang, Wei; Dutta, Suchandrima; Wang, Yigang 2022. Advances in Cellular Reprogramming-Based Approaches for Heart Regenerative Repair. Cells, 11 23, Jiang, Lin; Liang, Jialiang; Huang, Wei; Ma, Jianyong; Park, Ki Ho; Wu, Zhichao; Chen, Peng; Zhu, Hua; Ma, Jian-Jie; Cai, Wenfeng; Paul, Christian; Niu, Liang; Fan, Guo-Chang; Wang, Hong-Sheng; Kanisicak, Onur; Xu, Meifeng; Wang, Yigang 2022. CRISPR activation of endogenous genes reprograms fibroblasts into cardiovascular progenitor cells for myocardial infarction therapy. Molecular therapy : the journal of the American Society of Gene Therapy, 30 1, 54-74Wu, Zhichao; Liang, Jialiang; Huang, Wei; Jiang, Lin; Paul, Christian; Gao, Xiang; Alam, Perwez; Kanisicak, Onur; Xu, Meifeng; Wang, Yigang 2021. Immunomodulatory effects of mesenchymal stem cells for the treatment of cardiac allograft rejection. Experimental biology and medicine (Maywood, N.J.), 246 7, 851-860Wu, Zhichao; Liang, Jialiang; Huang, Wei; Jiang, Lin; Paul, Christian; Lin, Bonnie; Zheng, Junmeng; Wang, Yigang 2021. Prompt Graft Cooling Enhances Cardioprotection during Heart Transplantation Procedures through the Regulation of Mitophagy. Cells, 10 11, Jiang, Lin; Liang, Jialiang; Huang, Wei; Wu, Zhichao; Paul, Christian; Wang, Yigang 2020. Strategies and Challenges to Improve Cellular Programming-Based Approaches for Heart Regeneration Therapy. International journal of molecular sciences, 21 20, Liang, Jialiang; Huang, Wei; Jiang, Lin; Paul, Christian; Li, Xiangnan; Wang, Yigang 2019. Concise Review: Reduction of Adverse Cardiac Scarring Facilitates Pluripotent Stem Cell-Based Therapy for Myocardial Infarction. Stem cells (Dayton, Ohio), 37 7, 844-854Huang, Wei; Feng, Yuliang; Liang, Jialiang; Yu, Hao; Wang, Cheng; Wang, Boyu; Wang, Mingyang; Jiang, Lin; Meng, Wei; Cai, Wenfeng; Medvedovic, Mario; Chen, Jenny; Paul, Christian; Davidson, W Sean; Sadayappan, Sakthivel; Stambrook, Peter J; Yu, Xi-Yong; Wang, Yigang 2018. Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration. Nature communications, 9 1, 700Huang, Wei; Liang, Jialiang; Feng, Yuliang; Jia, Zhanfeng; Jiang, Lin; Cai, Wenfeng; Paul, Christian; Gu, Jianguo G; Stambrook, Peter J; Millard, Ronald W; Zhu, Xiao-Lan; Zhu, Ping; Wang, Yigang 2018. Heterogeneity of adult masseter muscle satellite cells with cardiomyocyte differentiation potential. Experimental cell research, 371 1, 20-30Ma, Ruilian; Liang, Jialiang; Huang, Wei; Guo, Linlin; Cai, Wenfeng; Wang, Lei; Paul, Christian; Yang, Huang-Tian; Kim, Ha Won; Wang, Yigang 2018. Electrical Stimulation Enhances Cardiac Differentiation of Human Induced Pluripotent Stem Cells for Myocardial Infarction Therapy. Antioxidants & redox signaling, 28 5, 371-384Liang, Jialiang; Huang, Wei; Cai, Wenfeng; Wang, Lei; Guo, Linlin; Paul, Christian; Yu, Xi-Yong; Wang, Yigang 2017. Inhibition of microRNA-495 Enhances Therapeutic Angiogenesis of Human Induced Pluripotent Stem Cells. Stem cells (Dayton, Ohio), 35 2, 337-350Cai, Wen-Feng; Kang, Kai; Huang, Wei; Liang, Jia-Liang; Feng, Yu-Liang; Liu, Guan-Sheng; Chang, De-Hua; Wen, Zhi-Li; Paul, Christian; Xu, Meifeng; Millard, Ronald W; Wang, Yigang 2015. CXCR4 attenuates cardiomyocytes mitochondrial dysfunction to resist ischaemia-reperfusion injury. Journal of cellular and molecular medicine, 19 8, 1825-35Liang, Jialiang; Huang, Wei; Yu, Xiyong; Ashraf, Atif; Wary, Kishore K; Xu, Meifeng; Millard, Ronald W; Ashraf, Muhammad; Wang, Yigang 2012. Suicide gene reveals the myocardial neovascularization role of mesenchymal stem cells overexpressing CXCR4 (MSC(CXCR4)). PloS one, 7 9, e46158Yu, Xi-Yong; Geng, Yong-Jian; Liang, Jia-Liang; Zhang, Saidan; Lei, He-Ping; Zhong, Shi-Long; Lin, Qiu-Xiong; Shan, Zhi-Xin; Lin, Shu-Guang; Li, Yangxin 2012. High levels of glucose induce "metabolic memory" in cardiomyocyte via epigenetic histone H3 lysine 9 methylation. Molecular biology reports, 39 9, 8891-8Liang, Jia-Liang; Feng, Zhi-Kuan; Liu, Xiao-Ying; Lin, Qiu-Xiong; Fu, Yong-Heng; Shan, Zhi-Xin; Zhu, Jie-Ning; Lin, Shu-Guang; Yu, Xi-Yong 2011. Effect of impaired glucose tolerance on cardiac dysfunction in a rat model of prediabetes. Chinese medical journal, 124 5, 734-9Yu, Xi-Yong; Chen, Hong-Mei; Liang, Jia-Liang; Lin, Qiu-Xiong; Tan, Hong-Hong; Fu, Yong-Heng; Liu, Xiao-Ying; Shan, Zhi-Xin; Li, Xiao-Hong; Yang, Hua-Zhang; Yang, Min; Li, Yangxin; Lin, Shu-Guang 2011. Hyperglycemic myocardial damage is mediated by proinflammatory cytokine: macrophage migration inhibitory factor. PloS one, 6 1, e16239Liang, Jia-Liang; Xiao, Ding-Zhang; Liu, Xiao-Ying; Lin, Qiu-Xiong; Shan, Zhi-Xin; Zhu, Jie-Ning; Lin, Shu-Guang; Yu, Xi-Yong 2010. High glucose induces apoptosis in AC16 human cardiomyocytes via macrophage migration inhibitory factor and c-Jun N-terminal kinase. Clinical and experimental pharmacology & physiology, 37 10, 969-73Yu, Xi-Yong; Geng, Yong-Jian; Liang, Jia-Liang; Lin, Qiu-Xiong; Lin, Shu-Guang; Zhang, Saidan; Li, Yangxin 2010. High levels of glucose induce apoptosis in cardiomyocyte via epigenetic regulation of the insulin-like growth factor receptor. Experimental cell research, 316 17, 2903-9
He, Xingyu; Dutta, Suchandrima; Liang, Jialiang; Paul, Christian; Huang, Wei; Xu, Meifeng; Chang, Vivian; Wang, Yigang 2023. Direct Cellular Reprogramming Techniques for Cardiovascular Regenerative Therapeutics. Canadian journal of physiology and pharmacology, , Park, Ki Ho; He, Xingyu; Jiang, Lin; Zhu, Hua; Liang, Jialiang; Wang, Yigang; Ma, Jianjie 2023. Activation of MG53 Enhances Cell Survival and Engraftment of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Injured Hearts. Stem cell reviews and reports, 19 7, 2420-2428Wu, Zhichao; Huang, Wei; He, Xingyu; Dutta, Suchandrima; Paul, Christian; Fan, Guo-Chang; Kanisicak, Onur; Xu, Meifeng; Liang, Jialiang; Wang, Yigang 2023. Myocardial IGF2R is a critical mediator of inflammation and fibrosis after ischemia-reperfusion injury. bioRxiv : the preprint server for biology, , He, Xingyu; Liang, Jialiang; Paul, Christian; Huang, Wei; Dutta, Suchandrima; Wang, Yigang 2022. Advances in Cellular Reprogramming-Based Approaches for Heart Regenerative Repair. Cells, 11 23, Jiang, Lin; Liang, Jialiang; Huang, Wei; Ma, Jianyong; Park, Ki Ho; Wu, Zhichao; Chen, Peng; Zhu, Hua; Ma, Jian-Jie; Cai, Wenfeng; Paul, Christian; Niu, Liang; Fan, Guo-Chang; Wang, Hong-Sheng; Kanisicak, Onur; Xu, Meifeng; Wang, Yigang 2022. CRISPR activation of endogenous genes reprograms fibroblasts into cardiovascular progenitor cells for myocardial infarction therapy. Molecular therapy : the journal of the American Society of Gene Therapy, 30 1, 54-74Wu, Zhichao; Liang, Jialiang; Huang, Wei; Jiang, Lin; Paul, Christian; Gao, Xiang; Alam, Perwez; Kanisicak, Onur; Xu, Meifeng; Wang, Yigang 2021. Immunomodulatory effects of mesenchymal stem cells for the treatment of cardiac allograft rejection. Experimental biology and medicine (Maywood, N.J.), 246 7, 851-860Wu, Zhichao; Liang, Jialiang; Huang, Wei; Jiang, Lin; Paul, Christian; Lin, Bonnie; Zheng, Junmeng; Wang, Yigang 2021. Prompt Graft Cooling Enhances Cardioprotection during Heart Transplantation Procedures through the Regulation of Mitophagy. Cells, 10 11, Jiang, Lin; Liang, Jialiang; Huang, Wei; Wu, Zhichao; Paul, Christian; Wang, Yigang 2020. Strategies and Challenges to Improve Cellular Programming-Based Approaches for Heart Regeneration Therapy. International journal of molecular sciences, 21 20, Liang, Jialiang; Huang, Wei; Jiang, Lin; Paul, Christian; Li, Xiangnan; Wang, Yigang 2019. Concise Review: Reduction of Adverse Cardiac Scarring Facilitates Pluripotent Stem Cell-Based Therapy for Myocardial Infarction. Stem cells (Dayton, Ohio), 37 7, 844-854Huang, Wei; Feng, Yuliang; Liang, Jialiang; Yu, Hao; Wang, Cheng; Wang, Boyu; Wang, Mingyang; Jiang, Lin; Meng, Wei; Cai, Wenfeng; Medvedovic, Mario; Chen, Jenny; Paul, Christian; Davidson, W Sean; Sadayappan, Sakthivel; Stambrook, Peter J; Yu, Xi-Yong; Wang, Yigang 2018. Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration. Nature communications, 9 1, 700Huang, Wei; Liang, Jialiang; Feng, Yuliang; Jia, Zhanfeng; Jiang, Lin; Cai, Wenfeng; Paul, Christian; Gu, Jianguo G; Stambrook, Peter J; Millard, Ronald W; Zhu, Xiao-Lan; Zhu, Ping; Wang, Yigang 2018. Heterogeneity of adult masseter muscle satellite cells with cardiomyocyte differentiation potential. Experimental cell research, 371 1, 20-30Ma, Ruilian; Liang, Jialiang; Huang, Wei; Guo, Linlin; Cai, Wenfeng; Wang, Lei; Paul, Christian; Yang, Huang-Tian; Kim, Ha Won; Wang, Yigang 2018. Electrical Stimulation Enhances Cardiac Differentiation of Human Induced Pluripotent Stem Cells for Myocardial Infarction Therapy. Antioxidants & redox signaling, 28 5, 371-384Liang, Jialiang; Huang, Wei; Cai, Wenfeng; Wang, Lei; Guo, Linlin; Paul, Christian; Yu, Xi-Yong; Wang, Yigang 2017. Inhibition of microRNA-495 Enhances Therapeutic Angiogenesis of Human Induced Pluripotent Stem Cells. Stem cells (Dayton, Ohio), 35 2, 337-350Cai, Wen-Feng; Kang, Kai; Huang, Wei; Liang, Jia-Liang; Feng, Yu-Liang; Liu, Guan-Sheng; Chang, De-Hua; Wen, Zhi-Li; Paul, Christian; Xu, Meifeng; Millard, Ronald W; Wang, Yigang 2015. CXCR4 attenuates cardiomyocytes mitochondrial dysfunction to resist ischaemia-reperfusion injury. Journal of cellular and molecular medicine, 19 8, 1825-35Liang, Jialiang; Huang, Wei; Yu, Xiyong; Ashraf, Atif; Wary, Kishore K; Xu, Meifeng; Millard, Ronald W; Ashraf, Muhammad; Wang, Yigang 2012. Suicide gene reveals the myocardial neovascularization role of mesenchymal stem cells overexpressing CXCR4 (MSC(CXCR4)). PloS one, 7 9, e46158Yu, Xi-Yong; Geng, Yong-Jian; Liang, Jia-Liang; Zhang, Saidan; Lei, He-Ping; Zhong, Shi-Long; Lin, Qiu-Xiong; Shan, Zhi-Xin; Lin, Shu-Guang; Li, Yangxin 2012. High levels of glucose induce "metabolic memory" in cardiomyocyte via epigenetic histone H3 lysine 9 methylation. Molecular biology reports, 39 9, 8891-8Liang, Jia-Liang; Feng, Zhi-Kuan; Liu, Xiao-Ying; Lin, Qiu-Xiong; Fu, Yong-Heng; Shan, Zhi-Xin; Zhu, Jie-Ning; Lin, Shu-Guang; Yu, Xi-Yong 2011. Effect of impaired glucose tolerance on cardiac dysfunction in a rat model of prediabetes. Chinese medical journal, 124 5, 734-9Yu, Xi-Yong; Chen, Hong-Mei; Liang, Jia-Liang; Lin, Qiu-Xiong; Tan, Hong-Hong; Fu, Yong-Heng; Liu, Xiao-Ying; Shan, Zhi-Xin; Li, Xiao-Hong; Yang, Hua-Zhang; Yang, Min; Li, Yangxin; Lin, Shu-Guang 2011. Hyperglycemic myocardial damage is mediated by proinflammatory cytokine: macrophage migration inhibitory factor. PloS one, 6 1, e16239Liang, Jia-Liang; Xiao, Ding-Zhang; Liu, Xiao-Ying; Lin, Qiu-Xiong; Shan, Zhi-Xin; Zhu, Jie-Ning; Lin, Shu-Guang; Yu, Xi-Yong 2010. High glucose induces apoptosis in AC16 human cardiomyocytes via macrophage migration inhibitory factor and c-Jun N-terminal kinase. Clinical and experimental pharmacology & physiology, 37 10, 969-73Yu, Xi-Yong; Geng, Yong-Jian; Liang, Jia-Liang; Lin, Qiu-Xiong; Lin, Shu-Guang; Zhang, Saidan; Li, Yangxin 2010. High levels of glucose induce apoptosis in cardiomyocyte via epigenetic regulation of the insulin-like growth factor receptor. Experimental cell research, 316 17, 2903-9