Education/CredentialsFellowship: Case Western Reserve University (Cardiology)Fellowship: University of Cleveland (Clinical Cardiology )Residency : Presbyterian Hospital (Internal Medicine)Fellowship: Baylor University (Clinical Cardiology )Internship : Baylor University (Internal Medicine )Medical Degree: University of Texas Southwestern (Medicine)Bachelor's Degree/Master's Degree: State University of New York (Biology, Chemistry) Contact Information Veterans Admin Med Ctr Office 513-558-1067 Email rothenfr@ucmail.uc.edu Research InterestsMechanisms of Normal and Abnormal Cardiac Embryology, the Development of New Technologies for Investigation of the Early Embryonic Heart, the Biology of the Epicardium, Role of the Epicardium in Cardiac Repair in Patients with Ischemic Heart Disease, Translational Research Programs to More Efficiently Bring Bench Research to the Bedside. Peer Reviewed Publications Thompson, Jillian; Schacht, Sydney; Rothenberg, Florence 2019. Novel Antidiabetic Therapies and Cardiovascular Risk Reduction: The Role of the Noninferiority Trial. Cardiology clinics, 37 3, 335-343Rothenberg, Florence G; Clay, Michael B; Jamali, Hina; Vandivier-Pletsch, Robin H 2017. Systematic review of ? blocker, aspirin, and statin in critically ill patients: importance of severity of illness and cardiac troponin. Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 65 4, 747-753Poe, Stacy; Vandivier-Pletsch, Robin H; Clay, Michael; Wong, Hector R; Haynes, Erin; Rothenberg, Florence G 2015. Cardiac Troponin Measurement in the Critically Ill: Potential for Guiding Clinical Management. Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 63 8, 905-15Chatterjee, Tapan K; Stoll, Lynn L; Denning, Gerene M; Harrelson, Allan; Blomkalns, Andra L; Idelman, Gila; Rothenberg, Florence G; Neltner, Bonnie; Romig-Martin, Sara A; Dickson, Eric W; Rudich, Steven; Weintraub, Neal L 2009. Proinflammatory phenotype of perivascular adipocytes: influence of high-fat feeding. Circulation research, 104 4, 541-9Davis, A M; Rothenberg, F G; Shepherd, N; Izatt, J A 2008. In vivo spectral domain optical coherence tomography volumetric imaging and spectral Doppler velocimetry of early stage embryonic chicken heart development. Journal of the Optical Society of America. A, Optics, image science, and vision, 25 12, 3134-43Jenkins,M.W.; Adler,D.C.; Gargesha,M.; Huber,R.; Rothenberg,F.; Belding,J.; Watanabe,M.; Wilson,D.L.; Fujimoto,J.G.; Rollins,A.M. 2007. Ultrahigh-speed optical coherence tomography imaging and visualization of the embryonic avian heart using a buffered fourier domain mode locked laser Optics Express, 15 10, 6251Ripplinger,C.M.; Li,W.; Hadley,J.; Chen,J.; Rothenberg,F.; Lombardi,R.; Wickline,S.A.; Marian,A.J.; Efimov,I.R. 2007. Enhanced transmural fiber rotation and connexin 43 heterogeneity are associated with an increased upper limit of vulnerability in a transgenic rabbit model of human hypertrophic cardiomyopathy Circulation Research, 101 10, 1049Jenkins,M.W.; Rothenberg,F.; Roy,D.; Nikolski,V.P.; Hu,Z.; Watanabe,M.; Wilson,D.L.; Efimov,I.R.; Rollins,A.M. 2006. 4d embryonic cardiography using gated optical coherence tomography Optics Express, 14 2, 736Rothenberg,F.; Efimov,I.R. 2006. Three-dimensional anatomy of the conduction system of the early embryonic rabbit heart Anatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology, 288 1, 3Rothenberg,F.; Nikolski,V.P.; Watanabe,M.; Efimov,I.R. 2005. Electrophysiology and anatomy of embryonic rabbit hearts before and after septation American Journal of Physiology - Heart and Circulatory Physiology, 288 1 57-1, H344Rothenberg,F.; Watanabe,M.; Eloff,B.; Rosenbaum,D. 2005. Emerging patterns of cardiac conduction in the chick embryo: waveform analysis with photodiode array-based optical imaging Developmental Dynamics, 233 2, 456Efimov,I.R.; Nikolski,V.P.; Rothenberg,F.; Greener,I.D.; Li,J.; Dobrzynski,H.; Boyett,M. 2004. Structure-function relationship in the av junction Anatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology, 280 2, 952Rothenberg,F.; Efimov,I.R.; Watanabe,M. 2004. Functional imaging of the embryonic pacemaking and cardiac conduction system over the past 150 years: technologies to overcome the challenges Anatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology, 280 2, 980Rothenberg,F.; Fisher,S.A.; Watanabe,M. 2003. Sculpting the cardiac outflow tract Birth Defects Research Part C - Embryo Today: Reviews, 69 1, 38Rothenberg,F.; Hitomi,M.; Fisher,S.A.; Watanabe,M. 2002. Initiation of apoptosis in the developing avian outflow tract myocardium Developmental Dynamics, 223 4, 469Watanabe,M.; Hitomi,M.; Van der Wee,K.; Rothenberg,F.; Fisher,S.A.; Zucker,R.; Svoboda,K.K.H.; Goldsmith,E.C.; Heiskanen,K.M.; Nieminen,A.-L. 2002. The pros and cons of apoptosis assays for use in the study of cells, tissues, and organs Microscopy and Microanalysis, 8 5, 375Rothenberg,F.; Franklin,J.O.; DeMaio,S.J. 1994. Use, value, and toxicity of amiodarone Heart Disease and Stroke, 3 1, 19Rothenberg,F.; Schumacher,J.R.; Rosenthal,R.L. 1994. Near-fatal pulmonary air embolus from presumed inadvertent pressure placed on a partially empty plastic intravenous infusion bag American Journal of Cardiology, 73 13, 1035Baskin,D.S.; Simpson Jr.,R.K.; Browning,J.L.; Dudley,A.W.; Rothenberg,F.; Bogue,L. 1993. The effect of long-term high-dose naloxone infusion in experimental blunt spinal cord injury Journal of Spinal Disorders, 6 1, 38Simpson Jr.,R.K.; Baskin,D.S.; Dudley,A.W.; Bogue,L.; Rothenberg,F. 1991. The influence of long-term nifedipine or indomethacin therapy on neurologic recovery from experimental spinal cord injury Journal of Spinal Disorders, 4 4, 420
Research InterestsMechanisms of Normal and Abnormal Cardiac Embryology, the Development of New Technologies for Investigation of the Early Embryonic Heart, the Biology of the Epicardium, Role of the Epicardium in Cardiac Repair in Patients with Ischemic Heart Disease, Translational Research Programs to More Efficiently Bring Bench Research to the Bedside.
Peer Reviewed Publications Thompson, Jillian; Schacht, Sydney; Rothenberg, Florence 2019. Novel Antidiabetic Therapies and Cardiovascular Risk Reduction: The Role of the Noninferiority Trial. Cardiology clinics, 37 3, 335-343Rothenberg, Florence G; Clay, Michael B; Jamali, Hina; Vandivier-Pletsch, Robin H 2017. Systematic review of ? blocker, aspirin, and statin in critically ill patients: importance of severity of illness and cardiac troponin. Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 65 4, 747-753Poe, Stacy; Vandivier-Pletsch, Robin H; Clay, Michael; Wong, Hector R; Haynes, Erin; Rothenberg, Florence G 2015. Cardiac Troponin Measurement in the Critically Ill: Potential for Guiding Clinical Management. Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 63 8, 905-15Chatterjee, Tapan K; Stoll, Lynn L; Denning, Gerene M; Harrelson, Allan; Blomkalns, Andra L; Idelman, Gila; Rothenberg, Florence G; Neltner, Bonnie; Romig-Martin, Sara A; Dickson, Eric W; Rudich, Steven; Weintraub, Neal L 2009. Proinflammatory phenotype of perivascular adipocytes: influence of high-fat feeding. Circulation research, 104 4, 541-9Davis, A M; Rothenberg, F G; Shepherd, N; Izatt, J A 2008. In vivo spectral domain optical coherence tomography volumetric imaging and spectral Doppler velocimetry of early stage embryonic chicken heart development. Journal of the Optical Society of America. A, Optics, image science, and vision, 25 12, 3134-43Jenkins,M.W.; Adler,D.C.; Gargesha,M.; Huber,R.; Rothenberg,F.; Belding,J.; Watanabe,M.; Wilson,D.L.; Fujimoto,J.G.; Rollins,A.M. 2007. Ultrahigh-speed optical coherence tomography imaging and visualization of the embryonic avian heart using a buffered fourier domain mode locked laser Optics Express, 15 10, 6251Ripplinger,C.M.; Li,W.; Hadley,J.; Chen,J.; Rothenberg,F.; Lombardi,R.; Wickline,S.A.; Marian,A.J.; Efimov,I.R. 2007. Enhanced transmural fiber rotation and connexin 43 heterogeneity are associated with an increased upper limit of vulnerability in a transgenic rabbit model of human hypertrophic cardiomyopathy Circulation Research, 101 10, 1049Jenkins,M.W.; Rothenberg,F.; Roy,D.; Nikolski,V.P.; Hu,Z.; Watanabe,M.; Wilson,D.L.; Efimov,I.R.; Rollins,A.M. 2006. 4d embryonic cardiography using gated optical coherence tomography Optics Express, 14 2, 736Rothenberg,F.; Efimov,I.R. 2006. Three-dimensional anatomy of the conduction system of the early embryonic rabbit heart Anatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology, 288 1, 3Rothenberg,F.; Nikolski,V.P.; Watanabe,M.; Efimov,I.R. 2005. Electrophysiology and anatomy of embryonic rabbit hearts before and after septation American Journal of Physiology - Heart and Circulatory Physiology, 288 1 57-1, H344Rothenberg,F.; Watanabe,M.; Eloff,B.; Rosenbaum,D. 2005. Emerging patterns of cardiac conduction in the chick embryo: waveform analysis with photodiode array-based optical imaging Developmental Dynamics, 233 2, 456Efimov,I.R.; Nikolski,V.P.; Rothenberg,F.; Greener,I.D.; Li,J.; Dobrzynski,H.; Boyett,M. 2004. Structure-function relationship in the av junction Anatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology, 280 2, 952Rothenberg,F.; Efimov,I.R.; Watanabe,M. 2004. Functional imaging of the embryonic pacemaking and cardiac conduction system over the past 150 years: technologies to overcome the challenges Anatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology, 280 2, 980Rothenberg,F.; Fisher,S.A.; Watanabe,M. 2003. Sculpting the cardiac outflow tract Birth Defects Research Part C - Embryo Today: Reviews, 69 1, 38Rothenberg,F.; Hitomi,M.; Fisher,S.A.; Watanabe,M. 2002. Initiation of apoptosis in the developing avian outflow tract myocardium Developmental Dynamics, 223 4, 469Watanabe,M.; Hitomi,M.; Van der Wee,K.; Rothenberg,F.; Fisher,S.A.; Zucker,R.; Svoboda,K.K.H.; Goldsmith,E.C.; Heiskanen,K.M.; Nieminen,A.-L. 2002. The pros and cons of apoptosis assays for use in the study of cells, tissues, and organs Microscopy and Microanalysis, 8 5, 375Rothenberg,F.; Franklin,J.O.; DeMaio,S.J. 1994. Use, value, and toxicity of amiodarone Heart Disease and Stroke, 3 1, 19Rothenberg,F.; Schumacher,J.R.; Rosenthal,R.L. 1994. Near-fatal pulmonary air embolus from presumed inadvertent pressure placed on a partially empty plastic intravenous infusion bag American Journal of Cardiology, 73 13, 1035Baskin,D.S.; Simpson Jr.,R.K.; Browning,J.L.; Dudley,A.W.; Rothenberg,F.; Bogue,L. 1993. The effect of long-term high-dose naloxone infusion in experimental blunt spinal cord injury Journal of Spinal Disorders, 6 1, 38Simpson Jr.,R.K.; Baskin,D.S.; Dudley,A.W.; Bogue,L.; Rothenberg,F. 1991. The influence of long-term nifedipine or indomethacin therapy on neurologic recovery from experimental spinal cord injury Journal of Spinal Disorders, 4 4, 420
Thompson, Jillian; Schacht, Sydney; Rothenberg, Florence 2019. Novel Antidiabetic Therapies and Cardiovascular Risk Reduction: The Role of the Noninferiority Trial. Cardiology clinics, 37 3, 335-343Rothenberg, Florence G; Clay, Michael B; Jamali, Hina; Vandivier-Pletsch, Robin H 2017. Systematic review of ? blocker, aspirin, and statin in critically ill patients: importance of severity of illness and cardiac troponin. Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 65 4, 747-753Poe, Stacy; Vandivier-Pletsch, Robin H; Clay, Michael; Wong, Hector R; Haynes, Erin; Rothenberg, Florence G 2015. Cardiac Troponin Measurement in the Critically Ill: Potential for Guiding Clinical Management. Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 63 8, 905-15Chatterjee, Tapan K; Stoll, Lynn L; Denning, Gerene M; Harrelson, Allan; Blomkalns, Andra L; Idelman, Gila; Rothenberg, Florence G; Neltner, Bonnie; Romig-Martin, Sara A; Dickson, Eric W; Rudich, Steven; Weintraub, Neal L 2009. Proinflammatory phenotype of perivascular adipocytes: influence of high-fat feeding. Circulation research, 104 4, 541-9Davis, A M; Rothenberg, F G; Shepherd, N; Izatt, J A 2008. In vivo spectral domain optical coherence tomography volumetric imaging and spectral Doppler velocimetry of early stage embryonic chicken heart development. Journal of the Optical Society of America. A, Optics, image science, and vision, 25 12, 3134-43Jenkins,M.W.; Adler,D.C.; Gargesha,M.; Huber,R.; Rothenberg,F.; Belding,J.; Watanabe,M.; Wilson,D.L.; Fujimoto,J.G.; Rollins,A.M. 2007. Ultrahigh-speed optical coherence tomography imaging and visualization of the embryonic avian heart using a buffered fourier domain mode locked laser Optics Express, 15 10, 6251Ripplinger,C.M.; Li,W.; Hadley,J.; Chen,J.; Rothenberg,F.; Lombardi,R.; Wickline,S.A.; Marian,A.J.; Efimov,I.R. 2007. Enhanced transmural fiber rotation and connexin 43 heterogeneity are associated with an increased upper limit of vulnerability in a transgenic rabbit model of human hypertrophic cardiomyopathy Circulation Research, 101 10, 1049Jenkins,M.W.; Rothenberg,F.; Roy,D.; Nikolski,V.P.; Hu,Z.; Watanabe,M.; Wilson,D.L.; Efimov,I.R.; Rollins,A.M. 2006. 4d embryonic cardiography using gated optical coherence tomography Optics Express, 14 2, 736Rothenberg,F.; Efimov,I.R. 2006. Three-dimensional anatomy of the conduction system of the early embryonic rabbit heart Anatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology, 288 1, 3Rothenberg,F.; Nikolski,V.P.; Watanabe,M.; Efimov,I.R. 2005. Electrophysiology and anatomy of embryonic rabbit hearts before and after septation American Journal of Physiology - Heart and Circulatory Physiology, 288 1 57-1, H344Rothenberg,F.; Watanabe,M.; Eloff,B.; Rosenbaum,D. 2005. Emerging patterns of cardiac conduction in the chick embryo: waveform analysis with photodiode array-based optical imaging Developmental Dynamics, 233 2, 456Efimov,I.R.; Nikolski,V.P.; Rothenberg,F.; Greener,I.D.; Li,J.; Dobrzynski,H.; Boyett,M. 2004. Structure-function relationship in the av junction Anatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology, 280 2, 952Rothenberg,F.; Efimov,I.R.; Watanabe,M. 2004. Functional imaging of the embryonic pacemaking and cardiac conduction system over the past 150 years: technologies to overcome the challenges Anatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology, 280 2, 980Rothenberg,F.; Fisher,S.A.; Watanabe,M. 2003. Sculpting the cardiac outflow tract Birth Defects Research Part C - Embryo Today: Reviews, 69 1, 38Rothenberg,F.; Hitomi,M.; Fisher,S.A.; Watanabe,M. 2002. Initiation of apoptosis in the developing avian outflow tract myocardium Developmental Dynamics, 223 4, 469Watanabe,M.; Hitomi,M.; Van der Wee,K.; Rothenberg,F.; Fisher,S.A.; Zucker,R.; Svoboda,K.K.H.; Goldsmith,E.C.; Heiskanen,K.M.; Nieminen,A.-L. 2002. The pros and cons of apoptosis assays for use in the study of cells, tissues, and organs Microscopy and Microanalysis, 8 5, 375Rothenberg,F.; Franklin,J.O.; DeMaio,S.J. 1994. Use, value, and toxicity of amiodarone Heart Disease and Stroke, 3 1, 19Rothenberg,F.; Schumacher,J.R.; Rosenthal,R.L. 1994. Near-fatal pulmonary air embolus from presumed inadvertent pressure placed on a partially empty plastic intravenous infusion bag American Journal of Cardiology, 73 13, 1035Baskin,D.S.; Simpson Jr.,R.K.; Browning,J.L.; Dudley,A.W.; Rothenberg,F.; Bogue,L. 1993. The effect of long-term high-dose naloxone infusion in experimental blunt spinal cord injury Journal of Spinal Disorders, 6 1, 38Simpson Jr.,R.K.; Baskin,D.S.; Dudley,A.W.; Bogue,L.; Rothenberg,F. 1991. The influence of long-term nifedipine or indomethacin therapy on neurologic recovery from experimental spinal cord injury Journal of Spinal Disorders, 4 4, 420