Education/CredentialsPost Doctoral Fellowship: Baylor College of Medicine (Molecular Endocrinology )Doctoral Degree: University of Texas (Biomedical Sciences)Master's Degree: University of Texas Graduate School of Biomedical Sciences (Molecular Biology)Bachelor's Degree: Bejing Normal University (Biology) Contact Information Vontz Center 1424 Office 513-558-5109 Email lusa@ucmail.uc.edu Research InterestsProstate and Breast, Molecular Endocrinology, Integrative Biology and Pharmacology, Molecular and Cellular Biology, Hematology Oncology Peer Reviewed Publications Dong,Z.Y., Liu,Y., Levin,L., Oleksowicz,L., Wang,J., and Lu, S. 2011. Vav3 oncogene is involved in regulation of secretory phospholipase A2-IIa expression in prostate cancer Oncology Reports, 25 6, 1511-6Dong,Z.Y., Liu,Y., Levin,L., Scott,K., Gaitonde,K., Wang,J., Zhai,Q., Oleksowicz,L., and Lu, S. 2010. Secretory phospholipase A2-IIa is involved in prostate cancer progression and may potentially serve as a biomarker for prostate cancer Carcinogenesis, 31 , 1948-1955Liu,Y., Wu,X., Dong,Z.Y., and Lu,S. 2010. The molecular mechanisms of Vav3 oncogene activation of androgen receptor in human prostate cancer cells Int J Oncol., 36 , 623-633Lu, S., Tan,Z., Wortman,M., Lu,S., and Dong,Z.U. 2010. Preferential Induction of G1 Arrest in Androgen Responsive Human Prostate Cancer Cells by Androgen Receptor Signaling Antagonists DL3 and antiandrogen bicalutamide Cancer Letters, 298 , 250-7Lu,S., Tan,Z., Wortaman,M., Lu,S., and Dong,Z.Y. 2010. Androgen receptor-dependent regulation of heat shock protein 70 in human prostate cancer cells Int J Oncol., 36 , 459-467Lee,K, Liu,Y., Mo,J.Q., Zhang,J., Dong, Z.Y., Lu, S 2008. Vav3 oncogene activates estrogen receptor and its overexpression may be involved in human breast cancer BCM cancer, 8 , 158Liu,Y., Mo,J.Q., Hu,Q., Boivin,G., Levin,L., Lu.S., Yang,D., Dong,Z.Y., and Lu,S 2008. Targeted overexpression of Vav3 oncogene in prostatic epithelium induces nonbacterial prostatitis and prostate cancer Cancer Research, 68 , 6396-6406Lu, S., Wang, A., Lu, S., and Dong, Z.Y 2007. DL3 is a novel anti-androgen and interrupts androgen receptor signaling in prostate cancer cells Mol. Cancer Ther, 6 7, 2057-2064Lu,S., Lee,J., Revelo,M., Wang,X., Lu,S., and Dong,Z.Y 2007. Smad3 is overexpressed in advanced human prostate cancer and necessary for progressive growth of prostate cancer cells in nude mice Clinical Cancer Research, 13 19, 5692-702Dong,Z.Y., Liu,Y., Lee,K., Lu,S., Wang, A., Wang,L.H., Revelo,M., and Lu,S 2006. Vav3 oncogene is overexpressed and regulates cell growth and androgen receptor activity in human prostate cancer Mol. Endo., 20 , 2315-2325
Research InterestsProstate and Breast, Molecular Endocrinology, Integrative Biology and Pharmacology, Molecular and Cellular Biology, Hematology Oncology
Peer Reviewed Publications Dong,Z.Y., Liu,Y., Levin,L., Oleksowicz,L., Wang,J., and Lu, S. 2011. Vav3 oncogene is involved in regulation of secretory phospholipase A2-IIa expression in prostate cancer Oncology Reports, 25 6, 1511-6Dong,Z.Y., Liu,Y., Levin,L., Scott,K., Gaitonde,K., Wang,J., Zhai,Q., Oleksowicz,L., and Lu, S. 2010. Secretory phospholipase A2-IIa is involved in prostate cancer progression and may potentially serve as a biomarker for prostate cancer Carcinogenesis, 31 , 1948-1955Liu,Y., Wu,X., Dong,Z.Y., and Lu,S. 2010. The molecular mechanisms of Vav3 oncogene activation of androgen receptor in human prostate cancer cells Int J Oncol., 36 , 623-633Lu, S., Tan,Z., Wortman,M., Lu,S., and Dong,Z.U. 2010. Preferential Induction of G1 Arrest in Androgen Responsive Human Prostate Cancer Cells by Androgen Receptor Signaling Antagonists DL3 and antiandrogen bicalutamide Cancer Letters, 298 , 250-7Lu,S., Tan,Z., Wortaman,M., Lu,S., and Dong,Z.Y. 2010. Androgen receptor-dependent regulation of heat shock protein 70 in human prostate cancer cells Int J Oncol., 36 , 459-467Lee,K, Liu,Y., Mo,J.Q., Zhang,J., Dong, Z.Y., Lu, S 2008. Vav3 oncogene activates estrogen receptor and its overexpression may be involved in human breast cancer BCM cancer, 8 , 158Liu,Y., Mo,J.Q., Hu,Q., Boivin,G., Levin,L., Lu.S., Yang,D., Dong,Z.Y., and Lu,S 2008. Targeted overexpression of Vav3 oncogene in prostatic epithelium induces nonbacterial prostatitis and prostate cancer Cancer Research, 68 , 6396-6406Lu, S., Wang, A., Lu, S., and Dong, Z.Y 2007. DL3 is a novel anti-androgen and interrupts androgen receptor signaling in prostate cancer cells Mol. Cancer Ther, 6 7, 2057-2064Lu,S., Lee,J., Revelo,M., Wang,X., Lu,S., and Dong,Z.Y 2007. Smad3 is overexpressed in advanced human prostate cancer and necessary for progressive growth of prostate cancer cells in nude mice Clinical Cancer Research, 13 19, 5692-702Dong,Z.Y., Liu,Y., Lee,K., Lu,S., Wang, A., Wang,L.H., Revelo,M., and Lu,S 2006. Vav3 oncogene is overexpressed and regulates cell growth and androgen receptor activity in human prostate cancer Mol. Endo., 20 , 2315-2325
Dong,Z.Y., Liu,Y., Levin,L., Oleksowicz,L., Wang,J., and Lu, S. 2011. Vav3 oncogene is involved in regulation of secretory phospholipase A2-IIa expression in prostate cancer Oncology Reports, 25 6, 1511-6Dong,Z.Y., Liu,Y., Levin,L., Scott,K., Gaitonde,K., Wang,J., Zhai,Q., Oleksowicz,L., and Lu, S. 2010. Secretory phospholipase A2-IIa is involved in prostate cancer progression and may potentially serve as a biomarker for prostate cancer Carcinogenesis, 31 , 1948-1955Liu,Y., Wu,X., Dong,Z.Y., and Lu,S. 2010. The molecular mechanisms of Vav3 oncogene activation of androgen receptor in human prostate cancer cells Int J Oncol., 36 , 623-633Lu, S., Tan,Z., Wortman,M., Lu,S., and Dong,Z.U. 2010. Preferential Induction of G1 Arrest in Androgen Responsive Human Prostate Cancer Cells by Androgen Receptor Signaling Antagonists DL3 and antiandrogen bicalutamide Cancer Letters, 298 , 250-7Lu,S., Tan,Z., Wortaman,M., Lu,S., and Dong,Z.Y. 2010. Androgen receptor-dependent regulation of heat shock protein 70 in human prostate cancer cells Int J Oncol., 36 , 459-467Lee,K, Liu,Y., Mo,J.Q., Zhang,J., Dong, Z.Y., Lu, S 2008. Vav3 oncogene activates estrogen receptor and its overexpression may be involved in human breast cancer BCM cancer, 8 , 158Liu,Y., Mo,J.Q., Hu,Q., Boivin,G., Levin,L., Lu.S., Yang,D., Dong,Z.Y., and Lu,S 2008. Targeted overexpression of Vav3 oncogene in prostatic epithelium induces nonbacterial prostatitis and prostate cancer Cancer Research, 68 , 6396-6406Lu, S., Wang, A., Lu, S., and Dong, Z.Y 2007. DL3 is a novel anti-androgen and interrupts androgen receptor signaling in prostate cancer cells Mol. Cancer Ther, 6 7, 2057-2064Lu,S., Lee,J., Revelo,M., Wang,X., Lu,S., and Dong,Z.Y 2007. Smad3 is overexpressed in advanced human prostate cancer and necessary for progressive growth of prostate cancer cells in nude mice Clinical Cancer Research, 13 19, 5692-702Dong,Z.Y., Liu,Y., Lee,K., Lu,S., Wang, A., Wang,L.H., Revelo,M., and Lu,S 2006. Vav3 oncogene is overexpressed and regulates cell growth and androgen receptor activity in human prostate cancer Mol. Endo., 20 , 2315-2325