Education/CredentialsPost-Doctoral Training: University of Alabama at Birmingham (Biochemistry/Mass Spectrom.)Post-Doctoral Training: Johns Hopkins School of Medicine (Biochemistry/Glycobiology)Doctoral Degree: University of Kentucky (Biochemistry)Bachelor's Degree: Centre College (Biology) Contact Information Vontz Center 2304 Office 513-558-7102 Email greiskd@ucmail.uc.edu Research InterestsBiological mass spectrometry Quantitative proteomics Global profiling of PTM dynamics Mechanistic understanding of cellular processes and disease Managing and delivering share resources to the research community Peer Reviewed Publications Bennett, Joshua Ruina; Ishikawa, Chiharu; Agarwal, Puneet; Yeung, Jennifer; Sampson, Avery; Uible, Emma; Vick, Eric; Bolanos, Lyndsey; Hueneman, Kathleen M; Wunderlich, Mark; Kolt, Amal; Choi, Kwangmin; Volk, Andrew G; Greis, Kenneth D; Rosenbaum, Jan S; Hoyt, Scott; Thomas, Craig J; Starczynowski, Daniel T 2023. Paralog-specific signaling by IRAK1/4 maintains MyD88-independent functions in MDS/AML. Blood, , Dean, Sarai T; Ishikawa, Chiharu; Zhu, Xiaoqin; Walulik, Sean; Nixon, Timothy; Jordan, Jessica K; Henderson, Samantha; Wyder, Michael; Salomonis, Nathan; Wunderlich, Mark; Greis, Kenneth D; Starczynowski, Daniel T; Volk, Andrew G 2023. Repression of TRIM13 by chromatin assembly factor CHAF1B is critical for AML development. Blood advances, , Uehara, Yasuaki; Tanaka, Yusuke; Zhao, Shuyang; Nikolaidis, Nikolaos M; Pitstick, Lori B; Wu, Huixing; Yu, Jane J; Zhang, Erik; Hasegawa, Yoshihiro; Noel, John G; Gardner, Jason C; Kopras, Elizabeth J; Haffey, Wendy D; Greis, Kenneth D; Guo, Jinbang; Woods, Jason C; Wikenheiser-Brokamp, Kathryn A; Kyle, Jennifer E; Ansong, Charles; Teitelbaum, Steven L; Inoue, Yoshikazu; Altinişik, Göksel; Xu, Yan; McCormack, Francis X 2023. Insights into pulmonary phosphate homeostasis and osteoclastogenesis emerge from the study of pulmonary alveolar microlithiasis. Nature communications, 14 1, 1205Barreyro, Laura; Sampson, Avery M; Ishikawa, Chiharu; Hueneman, Kathleen M; Choi, Kwangmin; Pujato, Mario A; Chutipongtanate, Somchai; Wyder, Michael; Haffey, Wendy D; O'Brien, Eric; Wunderlich, Mark; Ramesh, Vighnesh; Kolb, Ellen M; Meydan, Cem; Neelamraju, Yaseswini; Bolanos, Lyndsey C; Christie, Susanne; Smith, Molly A; Niederkorn, Madeline; Muto, Tomoya; Kesari, Santosh; Garrett-Bakelman, Francine E; Bartholdy, Boris; Will, Britta; Weirauch, Matthew T; Mulloy, James C; Gul, Zartash; Medlin, Stephen; Kovall, Rhett A; Melnick, Ari M; Perentesis, John P; Greis, Kenneth D; Nurmemmedov, Elmar; Seibel, William L; Starczynowski, Daniel T 2022. Blocking UBE2N abrogates oncogenic immune signaling in acute myeloid leukemia. Science translational medicine, 14 635, eabb7695Crowther, Rebecca R; Schmidt, Stephanie M; Lange, Shannon M; McKell, Melanie C; Robillard, Michelle C; Zhao, Junfang; Haffey, Wendy D; Wyder, Michael A; Greis, Kenneth D; Setchell, Kenneth D R; Qualls, Joseph E 2022. Cutting Edge: l-Arginine Transfer from Antigen-Presenting Cells Sustains CD4+ T Cell Viability and Proliferation. Journal of immunology (Baltimore, Md. : 1950), 208 4, 793-798Curry, Erin; Philpott, Megan E; Wojtusik, Jessye; Haffey, Wendy D; Wyder, Michael A; Greis, Kenneth D; Roth, Terri L 2022. Label-Free Quantification (LFQ) of Fecal Proteins for Potential Pregnancy Detection in Polar Bears. Life (Basel, Switzerland), 12 6, Kirley, Terence L; Greis, Kenneth D; Norman, Andrew B 2022. Tyrosine nitration of a humanized anti-cocaine mAb differentially affects ligand binding of cocaine and its metabolites. Biochemistry and biophysics reports, 30 , 101278Kirley, Terence L; Norman, Andrew B; Greis, Kenneth D 2022. Oxidation of specific tryptophan residues inhibits high affinity binding of cocaine and its metabolites to a humanized anti-cocaine mAb. The Journal of biological chemistry, , 101689Muto, Tomoya; Guillamot, Maria; Yeung, Jennifer; Fang, Jing; Bennett, Joshua; Nadorp, Bettina; Lasry, Audrey; Redondo, Luna Zea; Choi, Kwangmin; Gong, Yixiao; Walker, Callum S; Hueneman, Kathleen; Bolanos, Lyndsey C; Barreyro, Laura; Lee, Lynn H; Greis, Kenneth D; Vasyliev, Nikita; Khodadadi-Jamayran, Alireza; Nudler, Evgeny; Lujambio, Amaia; Lowe, Scott W; Aifantis, Iannis; Starczynowski, Daniel T 2022. TRAF6 functions as a tumor suppressor in myeloid malignancies by directly targeting MYC oncogenic activity. Cell stem cell, , Davis, Harold W; Vallabhapurapu, Subrahmanya D; Chu, Zhengtao; Wyder, Michael A; Greis, Kenneth D; Fannin, Venette; Sun, Ying; Desai, Pankaj B; Pak, Koon Y; Gray, Brian D; Qi, Xiaoyang 2020. Biotherapy of Brain Tumors with Phosphatidylserine-Targeted Radioiodinated SapC-DOPS Nanovesicles. Cells, 9 9, Dwivedi, Pankaj; Chutipongtanate, Somchai; Muench, David E; Azam, Mohammad; Grimes, H Leighton; Greis, Kenneth D 2020. SWATH-Proteomics of Ibrutinib's Action in Myeloid Leukemia Initiating Mutated G-CSFR Signaling. Proteomics. Clinical applications, , e1900144He, Quan; Wang, Fangfei; Honda, Takashi; Greis, Kenneth D; Redington, Andrew N 2020. Ablation of miR-144 increases vimentin expression and atherosclerotic plaque formation. Scientific reports, 10 1, 6127Huang, Huilin; Weng, Hengyou; Sun, Wenju; Qin, Xi; Shi, Hailing; Wu, Huizhe; Zhao, Boxuan Simen; Mesquita, Ana; Liu, Chang; Yuan, Celvie L; Hu, Yueh-Chiang; Hüttelmaier, Stefan; Skibbe, Jennifer R; Su, Rui; Deng, Xiaolan; Dong, Lei; Sun, Miao; Li, Chenying; Nachtergaele, Sigrid; Wang, Yungui; Hu, Chao; Ferchen, Kyle; Greis, Kenneth D; Jiang, Xi; Wei, Minjie; Qu, Lianghu; Guan, Jun-Lin; He, Chuan; Yang, Jianhua; Chen, Jianjun 2020. Publisher Correction: Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation. Nature cell biology, 22 10, 1288Manning, Janet R; Wijeratne, Aruna B; Oloizia, Brian B; Zhang, Yu; Greis, Kenneth D; Schultz, Jo El J 2020. Phosphoproteomic analysis identifies phospho-Threonine-17 site of phospholamban important in low molecular weight isoform of fibroblast growth factor 2-induced protection against post-ischemic cardiac dysfunction. Journal of molecular and cellular cardiology, 148 , 1-14Muench, David E; Olsson, Andre; Ferchen, Kyle; Pham, Giang; Serafin, Rachel A; Chutipongtanate, Somchai; Dwivedi, Pankaj; Song, Baobao; Hay, Stuart; Chetal, Kashish; Trump-Durbin, Lisa R; Mookerjee-Basu, Jayati; Zhang, Kejian; Yu, Jennifer C; Lutzko, Carolyn; Myers, Kasiani C; Nazor, Kristopher L; Greis, Kenneth D; Kappes, Dietmar J; Way, Sing Sing; Salomonis, Nathan; Grimes, H Leighton 2020. Mouse models of neutropenia reveal progenitor-stage-specific defects. Nature, 582 7810, 109-114Niederkorn, Madeline; Hueneman, Kathleen; Choi, Kwangmin; Varney, Melinda E; Romano, Laurel; Pujato, Mario A; Greis, Kenneth D; Inoue, Jun-Ichiro; Meetei, Ruhikanta; Starczynowski, Daniel T 2020. TIFAB Regulates USP15-Mediated p53 Signaling during Stressed and Malignant Hematopoiesis. Cell reports, 30 8, 2776-2790.e6Schieber, Michael; Marinaccio, Christian; Bolanos, Lyndsey C; Haffey, Wendy D; Greis, Kenneth D; Starczynowski, Daniel T; Crispino, John D 2020. FBXO11 is a candidate tumor suppressor in the leukemic transformation of myelodysplastic syndrome. Blood cancer journal, 10 10, 98Dwivedi, Pankaj; Muench, David E; Wagner, Michael; Azam, Mohammad; Grimes, H Leighton; Greis, Kenneth D 2019. Phospho serine and threonine analysis of normal and mutated granulocyte colony stimulating factor receptors. Scientific data, 6 1, 21Forster, Catherine S; Haffey, Wendy D; Bennett, Michael; Greis, Kenneth D; Devarajan, Prasad 2019. Identification of Urinary CD44 and Prosaposin as Specific Biomarkers of Urinary Tract Infections in Children With Neurogenic Bladders. Biomarker insights, 14 , 1177271919835570Turnier JL, Brunner HI, Bennett M, Aleed A, Gulati G, Haffey WD, Thornton S, Wagner M, Devarajan P, Witte D, Greis KD, Aronow B. 2019. Discovery of SERPINA3 as a candidate urinary biomarker of lupus nephritis activity Rheumatology, 58(2) , 321-330Chutipongtanate, Somchai; Greis, Kenneth D 2018. Multiplex Biomarker Screening Assay for Urinary Extracellular Vesicles Study: A Targeted Label-Free Proteomic Approach. Scientific reports, 8 1, 15039Dwivedi, Pankaj; Muench, David E; Wagner, Michael; Azam, Mohammad; Grimes, H Leighton; Greis, Kenneth D 2018. Time resolved quantitative phospho-tyrosine analysis reveals Bruton's Tyrosine kinase mediated signaling downstream of the mutated granulocyte-colony stimulating factor receptors. Leukemia, , Huang, Huilin; Weng, Hengyou; Sun, Wenju; Qin, Xi; Shi, Hailing; Wu, Huizhe; Zhao, Boxuan Simen; Mesquita, Ana; Liu, Chang; Yuan, Celvie L; Hu, Yueh-Chiang; Hüttelmaier, Stefan; Skibbe, Jennifer R; Su, Rui; Deng, Xiaolan; Dong, Lei; Sun, Miao; Li, Chenying; Nachtergaele, Sigrid; Wang, Yungui; Hu, Chao; Ferchen, Kyle; Greis, Kenneth D; Jiang, Xi; Wei, Minjie; Qu, Lianghu; Guan, Jun-Lin; He, Chuan; Yang, Jianhua; Chen, Jianjun 2018. Author Correction: Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation. Nature cell biology, 20 9, 1098Huang, Huilin; Weng, Hengyou; Sun, Wenju; Qin, Xi; Shi, Hailing; Wu, Huizhe; Zhao, Boxuan Simen; Mesquita, Ana; Liu, Chang; Yuan, Celvie L; Hu, Yueh-Chiang; Hüttelmaier, Stefan; Skibbe, Jennifer R; Su, Rui; Deng, Xiaolan; Dong, Lei; Sun, Miao; Li, Chenying; Nachtergaele, Sigrid; Wang, Yungui; Hu, Chao; Ferchen, Kyle; Greis, Kenneth D; Jiang, Xi; Wei, Minjie; Qu, Lianghu; Guan, Jun-Lin; He, Chuan; Yang, Jianhua; Chen, Jianjun 2018. Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation. Nature cell biology, 20 3, 285-295Kirley, Terence L; Greis, Kenneth D; Norman, Andrew B 2018. Domain unfolding of monoclonal antibody fragments revealed by non-reducing SDS-PAGE. Biochemistry and biophysics reports, 16 , 138-144Smith, Eric A; Krumpelbeck, Eric F; Jegga, Anil G; Prell, Malte; Matrka, Marie M; Kappes, Ferdinand; Greis, Kenneth D; Ali, Abdullah M; Meetei, Amom R; Wells, Susanne I 2018. The nuclear DEK interactome supports multi-functionality. Proteins, 86 1, 88-97Turnier, Jessica L; Brunner, Hermine I; Bennett, Michael; Aleed, Ashwaq; Gulati, Gaurav; Haffey, Wendy D; Thornton, Sherry; Wagner, Michael; Devarajan, Prasad; Witte, David; Greis, Kenneth D; Aronow, Bruce 2018. Discovery of SERPINA3 as a candidate urinary biomarker of lupus nephritis activity. Rheumatology (Oxford, England), , Yuan, Long; Mishra, Rosalin; Patel, Hima; Abdulsalam, Safnas; Greis, Kenneth D; Kadekaro, Ana Luisa; Merino, Edward J; Garrett, Joan T 2018. Utilization of Reactive Oxygen Species Targeted Therapy to Prolong the Efficacy of BRAF Inhibitors in Melanoma. Journal of Cancer, 9 24, 4665-4676Bennett, Michael R; Pleasant, LaTawnya; Haffner, Christopher; Ma, Qing; Haffey, Wendy D; Ying, Jun; Wagner, Michael; Greis, Kenneth D; Devarajan, Prasad 2017. A Novel Biomarker Panel to Identify Steroid Resistance in Childhood Idiopathic Nephrotic Syndrome. Biomarker insights, 12 , 1177271917695832Dwivedi, Pankaj; Greis, Kenneth D 2017. Granulocyte colony-stimulating factor receptor signaling in severe congenital neutropenia, chronic neutrophilic leukemia, and related malignancies. Experimental hematology, 46 , 9-20Fang, Jing; Bolanos, Lyndsey C; Choi, Kwangmin; Liu, Xiaona; Christie, Susanne; Akunuru, Shailaja; Kumar, Rupali; Wang, Dehua; Chen, Xiaoting; Greis, Kenneth D; Stoilov, Peter; Filippi, Marie-Dominique; Maciejewski, Jaroslaw P; Garcia-Manero, Guillermo; Weirauch, Matthew T; Salamonis, Nathan; Geiger, Hartmut; Zheng, Yi; Starczynowski, Daniel T 2017. Corrigendum: Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia. Nature immunology, 18 4, 474Fang, Jing; Bolanos, Lyndsey C; Choi, Kwangmin; Liu, Xiaona; Christie, Susanne; Akunuru, Shailaja; Kumar, Rupali; Wang, Dehua; Chen, Xiaoting; Greis, Kenneth D; Stoilov, Peter; Filippi, Marie-Dominique; Maciejewski, Jaroslaw P; Garcia-Manero, Guillermo; Weirauch, Matthew T; Salomonis, Nathan; Geiger, Hartmut; Zheng, Yi; Starczynowski, Daniel T 2017. Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia. Nature immunology, 18 2, 236-245Blanco, Víctor M; Chu, Zhengtao; LaSance, Kathleen; Gray, Brian D; Yan Pak, Koon; Rider, Therese; Greis, Kenneth D; Qi, Xiaoyang 2016. Optical and nuclear imaging of glioblastoma with phosphatidylserine-targeted nanovesicles. Oncotarget, , Heaven, Michael R; Funk, Adam J; Cobbs, Archie L; Haffey, Wendy D; Norris, Jeremy L; McCullumsmith, Robert E; Greis, Kenneth D 2016. Systematic evaluation of data-independent acquisition for sensitive and reproducible proteomics-a prototype design for a single injection assay. Journal of mass spectrometry : JMS, 51 1, 1-11Kirley, Terence L; Greis, Kenneth D; Norman, Andrew B 2016. Selective disulfide reduction for labeling and enhancement of Fab antibody fragments. Biochemical and biophysical research communications, 480 4, 752-757Kirley, Terence L; Greis, Kenneth D; Norman, Andrew B 2016. Structural characterization of expressed monoclonal antibodies by single sample mass spectral analysis after IdeS proteolysis. Biochemical and biophysical research communications, 477 3, 363-8Sedlacek, Christopher J; Nielsen, Susanne; Greis, Kenneth D; Haffey, Wendy D; Revsbech, Niels Peter; Ticak, Tomislav; Laanbroek, Hendrikus J; Bollmann, Annette 2016. Effects of Bacterial Community Members on the Proteome of the Ammonia-Oxidizing Bacterium Nitrosomonas sp. Strain Is79. Applied and environmental microbiology, 82 15, 4776-88Hasegawa, Kazuteru; Sin, Ho-Su; Maezawa, So; Broering, Tyler J; Kartashov, Andrey V; Alavattam, Kris G; Ichijima, Yosuke; Zhang, Fan; Bacon, W Clark; Greis, Kenneth D; Andreassen, Paul R; Barski, Artem; Namekawa, Satoshi H 2015. SCML2 establishes the male germline epigenome through regulation of histone H2A ubiquitination. Developmental cell, 32 5, 574-88Huang, Yan; Powers, Corey; Madala, Satish K; Greis, Kenneth D; Haffey, Wendy D; Towbin, Jeffrey A; Purevjav, Enkhsaikhan; Javadov, Sabzali; Strauss, Arnold W; Khuchua, Zaza 2015. Cardiac metabolic pathways affected in the mouse model of barth syndrome. PloS one, 10 6, e0128561Huang,Y., Powers,C., Madala,S. K., Greis,K. D., Haffey,W. D., Towbin,J. A., Purevjav,E., Javadov,S., Strauss,A. W., Khuchua,Z. 2015. Cardiac metabolic pathways affected in the mouse model of barth syndrome PloS one, 10 6, e0128561Lu, Xiaoming; Zoller, Erin E; Weirauch, Matthew T; Wu, Zhiguo; Namjou, Bahram; Williams, Adrienne H; Ziegler, Julie T; Comeau, Mary E; Marion, Miranda C; Glenn, Stuart B; Adler, Adam; Shen, Nan; Nath, Swapan K; Stevens, Anne M; Freedman, Barry I; Tsao, Betty P; Jacob, Chaim O; Kamen, Diane L; Brown, Elizabeth E; Gilkeson, Gary S; Alarcón, Graciela S; Reveille, John D; Anaya, Juan-Manuel; James, Judith A; Sivils, Kathy L; Criswell, Lindsey A; Vilá, Luis M; Alarcón-Riquelme, Marta E; Petri, Michelle; Scofield, R Hal; Kimberly, Robert P; Ramsey-Goldman, Rosalind; Joo, Young Bin; Choi, Jeongim; Bae, Sang-Cheol; Boackle, Susan A; Graham, Deborah Cunninghame; Vyse, Timothy J; Guthridge, Joel M; Gaffney, Patrick M; Langefeld, Carl D; Kelly, Jennifer A; Greis, Kenneth D; Kaufman, Kenneth M; Harley, John B; Kottyan, Leah C 2015. Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression. American journal of human genetics, 96 5, 731-9Marsh, J M; Davis, M G; Flagler, M J; Sun, Y; Chaudhary, T; Mamak, M; McComb, D W; Williams, R E A; Greis, K D; Rubio, L; Coderch, L 2015. Advanced hair damage model from ultra-violet radiation in the presence of copper. International journal of cosmetic science, 37 5, 532-41Marsh,J. M., Davis,M. G., Flagler,M. J., Sun,Y., Chaudhary,T., Mamak,M., McComb,D. W., Williams,R. E., Greis,K. D., Rubio,L., Coderch,L. 2015. Advanced hair damage model from ultra-violet radiation in the presence of copper International Journal of Cosmetic Science, 37 5, 532-41Thowfeik, Fathima Shazna; AbdulSalam, Safnas F; Wunderlich, Mark; Wyder, Michael; Greis, Kenneth D; Kadekaro, Ana L; Mulloy, James C; Merino, Edward J 2015. A ROS-Activatable Agent Elicits Homologous Recombination DNA Repair and Synergizes with Pathway Compounds. Chembiochem : a European journal of chemical biology, 16 17, 2513-21Wijeratne, Aruna B; Wijesundera, Dharshana N; Paulose, Maggie; Ahiabu, Ivy Belinda; Chu, Wei-Kan; Varghese, Oomman K; Greis, Kenneth D 2015. Phosphopeptide separation using radially aligned titania nanotubes on titanium wire. ACS applied materials & interfaces, 7 21, 11155-64Wijeratne,A. B., Wijesundera,D. N., Paulose,M., Ahiabu,I. B., Chu,W. K., Varghese,O. K., Greis,K. D. 2015. Phosphopeptide separation using radially aligned titania nanotubes on titanium wire ACS applied materials & interfaces, 7 21, 11155Liou B.;Haffey W.;Greis K.;Grabowski G. 2014. The LIMP-2/SCARB2 binding motif on acid Beta-Glucosidase: Basic and applied implications for Gaucher disease and associated neurodegenerative diseases Journal of Biological Chemistry, 289 43, 30063-74Liou, Benjamin; Haffey, Wendy D; Greis, Kenneth D; Grabowski, Gregory A 2014. The LIMP-2/SCARB2 binding motif on acid ?-glucosidase: basic and applied implications for Gaucher disease and associated neurodegenerative diseases. The Journal of biological chemistry, 289 43, 30063-74Marsh, JM; Iveson, R; Flagler, MJ; Davis, MG; Newland, AB; Greis, KD; Sun, Y; Chaudhary, T; Aistrup, ER 2014. Role of copper in photochemical damage to hair International journal of cosmetic science, 36 1, 32-8Green, Julianne V; Orsborn, Kris I; Zhang, Minlu; Tan, Queenie K G; Greis, Kenneth D; Porollo, Alexey; Andes, David R; Long Lu, Jason; Hostetter, Margaret K 2013. Heparin-binding motifs and biofilm formation by Candida albicans. The Journal of infectious diseases, 208 10, 1695-704Wijeratne, Aruna B; Manning, Janet R; Schultz, Jo El J; Greis, Kenneth D 2013. Quantitative phosphoproteomics using acetone-based Peptide labeling: method evaluation and application to a cardiac ischemia/reperfusion model. Journal of proteome research, 12 10, 4268-79Gauthamadasa, Kekulawalage; Vaitinadin, Nataraja Sarma; Dressman, James L; Macha, Stephen; Homan, Reyn; Greis, Kenneth D; Silva, R A Gangani D 2012. Apolipoprotein A-II-mediated conformational changes of apolipoprotein A-I in discoidal high density lipoproteins. The Journal of biological chemistry, 287 10, 7615-25Govindan, Suresh; McElligott, Andrew; Muthusamy, Saminathan; Nair, Nandini; Barefield, David; Martin, Jody L; Gongora, Enrique; Greis, Kenneth D; Luther, Pradeep K; Winegrad, Saul; Henderson, Kyle K; Sadayappan, Sakthivel 2012. Cardiac myosin binding protein-C is a potential diagnostic biomarker for myocardial infarction. Journal of molecular and cellular cardiology, 52 1, 154-64Kattamuri, Chandramohan; Luedeke, David M; Nolan, Kristof; Rankin, Scott A; Greis, Kenneth D; Zorn, Aaron M; Thompson, Thomas B 2012. Members of the DAN family are BMP antagonists that form highly stable noncovalent dimers. Journal of molecular biology, 424 5, 313-27Djung, Jane F; Mears, Richard J; Montalbetti, Christian A G N; Coulter, Thomas S; Golebiowski, Adam; Carr, Andrew N; Barker, Oliver; Greis, Kenneth D; Zhou, Songtao; Dolan, Elizabeth; Davis, Gregory F 2011. The synthesis and evaluation of indolylureas as PKC? inhibitors. Bioorganic & medicinal chemistry, 19 8, 2742-50Linares J.;Amanchy R.;Greis K.;Diaz-Meco M.;Moscat J. 2011. Author's correction: Phosphorylation of p62 by cdk1 controls the timely transit of cells through mit Molecular and Cellular Biology, 31 10, 2171Linares, Juan F; Amanchy, Ramars; Greis, Kenneth; Diaz-Meco, Maria T; Moscat, Jorge 2011. Phosphorylation of p62 by cdk1 controls the timely transit of cells through mitosis and tumor cell proliferation. Molecular and cellular biology, 31 1, 105-17Myer, David L; Robbins, Susan B; Yin, Moying; Boivin, Gregory P; Liu, Yang; Greis, Kenneth D; Bahassi, El Mustapha; Stambrook, Peter J 2011. Absence of polo-like kinase 3 in mice stabilizes Cdc25A after DNA damage but is not sufficient to produce tumors. Mutation research, 714 1-2, 1-10Piyaphanee, Nuntawan; Ma, Qing; Kremen, Oran; Czech, Kimberly; Greis, Kenneth; Mitsnefes, Mark; Devarajan, Prasad; Bennett, Michael R 2011. Discovery and initial validation of ? 1-B glycoprotein fragmentation as a differential urinary biomarker in pediatric steroid-resistant nephrotic syndrome. Proteomics. Clinical applications, 5 5-6, 334-42Ridsdale, Ross; Na, Cheng-Lun; Xu, Yan; Greis, Kenneth D; Weaver, Timothy 2011. Comparative proteomic analysis of lung lamellar bodies and lysosome-related organelles. PloS one, 6 1, e16482Rathore, Rakesh; Pribil, Patrick; Corr, Jay J; Seibel, William L; Evdokimov, Artem; Greis, Kenneth D 2010. Multiplex Enzyme Assays and Inhibitor Screening by Mass Spectrometry. Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening, , Aslan, Joseph E; You, Huihong; Williamson, Danielle M; Endig, Jessica; Youker, Robert T; Thomas, Laurel; Shu, Hongjun; Du, Yuhong; Milewski, Robert L; Brush, Matthew H; Possemato, Anthony; Sprott, Kam; Fu, Haian; Greis, Kenneth D; Runckel, Douglas N; Vogel, Arndt; Thomas, Gary 2009. Akt and 14-3-3 control a PACS-2 homeostatic switch that integrates membrane traffic with TRAIL-induced apoptosis. Molecular cell, 34 4, 497-509Eismann, Thorsten; Huber, Nadine; Shin, Thomas; Kuboki, Satoshi; Galloway, Elizabeth; Wyder, Michael; Edwards, Michael J; Greis, Kenneth D; Shertzer, Howard G; Fisher, Aron B; Lentsch, Alex B 2009. Peroxiredoxin-6 protects against mitochondrial dysfunction and liver injury during ischemia-reperfusion in mice. American journal of physiology. Gastrointestinal and liver physiology, 296 2, G266-74Haffey, Wendy D; Mikhaylova, Olga; Meller, Jarek; Yi, Ying; Greis, Kenneth D; Czyzyk-Krzeska, Maria F 2009. iTRAQ proteomic identification of pVHL-dependent and -independent targets of Egln1 prolyl hydroxylase knockdown in renal carcinoma cells. Advances in enzyme regulation, 49 1, 121-32Rathore, Rakesh; Corr, Jay J; Lebre, Daniel T; Seibel, William L; Greis, Kenneth D 2009. Extending matrix-assisted laser desorption/ionization triple quadrupole mass spectrometry enzyme screening assays to targets with small molecule substrates. Rapid communications in mass spectrometry : RCM, 23 20, 3293-300Stella, Caroline L; Bennett, Michael R; Devarajan, Prasad; Greis, Kenneth; Wyder, Michael; Macha, Stephen; Rao, Marepalli; Jodicke, Cristiano; Moussa, Hind; How, Helen Y; Myatt, Leslie; Webster, Rose; Sibai, Baha M 2009. Preterm labor biomarker discovery in serum using 3 proteomic profiling methodologies. American journal of obstetrics and gynecology, 201 4, 387.e1-13Suzuki, Michiko; Wiers, Kristina; Brooks, Elizabeth B; Greis, Kenneth D; Haines, Kathleen; Klein-Gitelman, Marisa S; Olson, Judyann; Onel, Karen; O 2009. Initial validation of a novel protein biomarker panel for active pediatric lupus nephritis. Pediatric research, 65 5, 530-6Mikhaylova, Olga; Ignacak, Monika L; Barankiewicz, Teresa J; Harbaugh, Svetlana V; Yi, Ying; Maxwell, Patrick H; Schneider, Martin; Van Geyte, Katie; Carmeliet, Peter; Revelo, Monica P; Wyder, Michael; Greis, Kenneth D; Meller, Jarek; Czyzyk-Krzeska, Maria F 2008. The von Hippel-Lindau tumor suppressor protein and Egl-9-Type proline hydroxylases regulate the large subunit of RNA polymerase II in response to oxidative stress. Molecular and cellular biology, 28 8, 2701-17Rathore, Rakesh; Corr, Jay; Scott, George; Vollmerhaus, Pauline; Greis, Kenneth D 2008. Development of an inhibitor screening platform via mass spectrometry. Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening, 13 10, 1007-13Greis, Kenneth D 2007. Mass spectrometry for enzyme assays and inhibitor screening: an emerging application in pharmaceutical research. Mass spectrometry reviews, 26 3, 324-39Greis, Kenneth D; Zhou, Songtao; Burt, Thomas M; Carr, Andrew N; Dolan, Elizabeth; Easwaran, Vijayasurian; Evdokimov, Artem; Kawamoto, Richard; Roesgen, Jeff; Davis, Gregory F 2006. MALDI-TOF MS as a label-free approach to rapid inhibitor screening. Journal of the American Society for Mass Spectrometry, 17 6, 815-22Greis, Kenneth D; Zhou, Songtao; Siehnel, Richard; Klanke, Chuck; Curnow, Alan; Howard, Jeremy; Layh-Schmitt, Gerlinde 2005. Development and validation of a whole-cell inhibition assay for bacterial methionine aminopeptidase by surface-enhanced laser desorption ionization-time of flight mass spectrometry. Antimicrobial agents and chemotherapy, 49 8, 3428-34Jarrold, Bradley; DeMuth, Jeffrey; Greis, Kenneth; Burt, Thomas; Wang, Feng 2005. An effective skeletal muscle prefractionation method to remove abundant structural proteins for optimized two-dimensional gel electrophoresis Electrophoresis, 26 11, 2269-78Peters, Kevin G; Davis, Mike G; Howard, Brian W; Pokross, Matthew; Rastogi, Vinit; Diven, Conrad; Greis, Kenneth D; Eby-Wilkens, Elaine; Maier, Matthew; Evdokimov, Artem; Soper, Shari; Genbauffe, Frank 2003. Mechanism of insulin sensitization by BMOV (bis maltolato oxo vanadium); unliganded vanadium (VO4) as the active component. Journal of inorganic biochemistry, 96 2-3, 321-30Thompson, Larry J; Wang, Feng; Proia, Alan D; Peters, Kevin G; Jarrold, Brad; Greis, Kenneth D 2003. Proteome analysis of the rat cornea during angiogenesis. Proteomics, 3 11, 2258-66Delinsky, David C; Greis, Kenneth D 2002. Capillary chromatography-coupled mass spectrometry with column switching for rapid identification of proteins from 2-dimensional electrophoresis gels. Journal of proteome research, 1 3, 279-84Isfort, Robert J; Wang, Feng; Greis, Kenneth D; Sun, Yiping; Keough, Thomas W; Bodine, Sue C; Anderson, N Leigh 2002. Proteomic analysis of rat soleus and tibialis anterior muscle following immobilization. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 769 2, 323-32Isfort, Robert J; Wang, Feng; Greis, Kenneth D; Sun, Yiping; Keough, Thomas W; Farrar, Roger P; Bodine, Sue C; Anderson, N Leigh 2002. Proteomic analysis of rat soleus muscle undergoing hindlimb suspension-induced atrophy and reweighting hypertrophy. Proteomics, 2 5, 543-50Egnaczyk, G F; Greis, K D; Stimson, E R; Maggio, J E 2001. Photoaffinity cross-linking of Alzheimer's disease amyloid fibrils reveals interstrand contact regions between assembled beta-amyloid peptide subunits. Biochemistry, 40 39, 11706-14Hoke S.;Morand K.;Greis K.;Baker T.;Harbol K.;Dobson R. 2001. Transformations in pharmaceutical research and development, driven by innovations in multidimensiona International Journal of Mass Spectrometry, 212 1-3, 135-196Isfort, R J; Hinkle, R T; Jones, M B; Wang, F; Greis, K D; Sun, Y; Keough, T W; Anderson, N L; Sheldon, R J 2000. Proteomic analysis of the atrophying rat soleus muscle following denervation. Electrophoresis, 21 11, 2228-34Sanchez, V; Greis, K D; Sztul, E; Britt, W J 2000. Accumulation of virion tegument and envelope proteins in a stable cytoplasmic compartment during human cytomegalovirus replication: characterization of a potential site of virus assembly. Journal of virology, 74 2, 975-86Smaill, ; Rewcastle, ; Loo, ; Greis, ; Chan, ; Reyner, ; Lipka, ; Showalter, ; Vincent, ; Elliott, ; Denny, 2000. Tyrosine kinase inhibitors. 17. Irreversible inhibitors of the epidermal growth factor receptor: 4-(Phenylamino)quinazoline- and 4-(Phenylamino)pyrido Journal of medicinal chemistry, 43 16, 3199Smaill, J B; Rewcastle, G W; Loo, J A; Greis, K D; Chan, O H; Reyner, E L; Lipka, E; Showalter, H D; Vincent, P W; Elliott, W L; Denny, W A 2000. Tyrosine kinase inhibitors. 17. Irreversible inhibitors of the epidermal growth factor receptor: 4-(phenylamino)quinazoline- and 4-(phenylamino)pyrido[3,2-d]pyrimidine-6-acrylamides bearing additional solubilizing functions. Journal of medicinal chemistry, 43 7, 1380-97VanBogelen, R A; Greis, K D; Blumenthal, R M; Tani, T H; Matthews, R G 1999. Mapping regulatory networks in microbial cells. Trends in microbiology, 7 8, 320-8Fry, D W; Bridges, A J; Denny, W A; Doherty, A; Greis, K D; Hicks, J L; Hook, K E; Keller, P R; Leopold, W R; Loo, J A; McNamara, D J; Nelson, J M; Sherwood, V; Smaill, J B; Trumpp-Kallmeyer, S; Dobrusin, E M 1998. Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor. Proceedings of the National Academy of Sciences of the United States of America, 95 20, 12022-7Greis, K D; Hart, G W 1998. Analytical methods for the study of O-GlcNAc glycoproteins and glycopeptides. Methods in molecular biology (Clifton, N.J.), 76 , 19-33Stevenson, T I; Loo, J A; Greis, K D 1998. Coupling capillary high-performance liquid chromatography to matrix-assisted laser desorption/ionization mass spectrometry and N-terminal sequencing of peptides via automated microblotting onto membrane substrates. Analytical biochemistry, 262 2, 99-109Greis K.D.;Hart G.W. 1997. Chapter 2 Nuclear and Cytoplasmic Glycoproteins New Comprehensive Biochemistry, 29 PART B, 33-54Greis, K D; Hayes, B K; Comer, F I; Kirk, M; Barnes, S; Lowary, T L; Hart, G W 1996. Selective detection and site-analysis of O-GlcNAc-modified glycopeptides by beta-elimination and tandem electrospray mass spectrometry. Analytical biochemistry, 234 1, 38-49Greis, K D; Zhu, S; Matalon, S 1996. Identification of nitration sites on surfactant protein A by tandem electrospray mass spectrometry. Archives of biochemistry and biophysics, 335 2, 396-402Hart G.W.;Greis K.D.;Dong L.Y.D.;Blomberg M.A.;Chou T.Y.;Jiang M.S.;Roquemore E.P.;Snow D.M.;Kreppel L.K.;Cole R.C.;Hayes B.K. 1995. Ubiquitous and temporal glycosylation of nuclear and cytoplasmic proteins Pure and Applied Chemistry, 67 10, 1637-1645Hart, G W; Greis, K D; Dong, L Y; Blomberg, M A; Chou, T Y; Jiang, M S; Roquemore, E P; Snow, D M; Kreppel, L K; Cole, R N 1995. O-linked N-acetylglucosamine: the "yin-yang" of Ser/Thr phosphorylation? Nuclear and cytoplasmic glycosylation. Advances in experimental medicine and biology, 376 , 115-23Hayes, B K; Greis, K D; Hart, G W 1995. Specific isolation of O-linked N-acetylglucosamine glycopeptides from complex mixtures. Analytical biochemistry, 228 1, 115-22Greis, K D; Gibson, W; Hart, G W 1994. Site-specific glycosylation of the human cytomegalovirus tegument basic phosphoprotein (UL32) at serine 921 and serine 952. Journal of virology, 68 12, 8339-49Greis, K D; Turco, S J; Thomas, J R; McConville, M J; Homans, S W; Ferguson, M A 1992. Purification and characterization of an extracellular phosphoglycan from Leishmania donovani. The Journal of biological chemistry, 267 9, 5876-81Thomas, J R; McConville, M J; Thomas-Oates, J E; Homans, S W; Ferguson, M A; Gorin, P A; Greis, K D; Turco, S J 1992. Refined structure of the lipophosphoglycan of Leishmania donovani. The Journal of biological chemistry, 267 10, 6829-33Crawford, I T; Greis, K D; Parks, L; Streips, U N 1987. Facile autoplast generation and transformation in Bacillus thuringiensis subsp. kurstaki. Journal of bacteriology, 169 12, 5423-8 Kirley T.L.; Greis K.D.; Norman A.B. 12-01-2018. Domain unfolding of monoclonal antibody fragments revealed by non-reducing SDS-PAGE Biochemistry and Biophysics Reports, 16 , 138-144 Jarrold B.; DeMuth J.; Greis K.; Burt T.; Wang F. 12-01-2005. An effective skeletal muscle prefractionation method to remove abundant structural proteins for opti AIChE Annual Meeting, Conference Proceedings, , 12387-12396 Delinsky D.; Greis K. 12-01-2002. Rapid capillary LC-ESI-MS/MS via column switching for proteomics applications Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics, , 155-156 Linares J.; Amanchy R.; Greis K.; Diaz-Meco M.; Moscat J. 08-01-2017. Correction: "Phosphorylation of p62 by cdk1 controls the timely transit of cells through mitosis and Molecular and Cellular Biology, 37 15, Bennett M.R.; Pleasant L.T.; Haffner C.; Ma Q.; Haffey W.D.; Ying J.; Wagner M.; Greis K.D.; Devarajan P. 03-08-2017. A novel biomarker panel to identify steroid resistance in childhood idiopathic nephrotic syndrome Biomarker Insights, 12 , Forster C.; Haffey W.; Bennett M.; Greis K.; Devarajan P. 03-01-2019. Identification of Urinary CD44 and Prosaposin as Specific Biomarkers of Urinary Tract Infections in Biomarker Insights, 14 , Yuan L.; Mishra R.; Patel H.; Abdulsalam S.; Greis K.; Kadekaro A.; Merino E.; Garrett J. 01-01-2018. Utilization of reactive oxygen species targeted therapy to prolong the efficacy of braf inhibitors i Journal of Cancer, 9 24, 4665-4676
Research InterestsBiological mass spectrometry Quantitative proteomics Global profiling of PTM dynamics Mechanistic understanding of cellular processes and disease Managing and delivering share resources to the research community
Peer Reviewed Publications Bennett, Joshua Ruina; Ishikawa, Chiharu; Agarwal, Puneet; Yeung, Jennifer; Sampson, Avery; Uible, Emma; Vick, Eric; Bolanos, Lyndsey; Hueneman, Kathleen M; Wunderlich, Mark; Kolt, Amal; Choi, Kwangmin; Volk, Andrew G; Greis, Kenneth D; Rosenbaum, Jan S; Hoyt, Scott; Thomas, Craig J; Starczynowski, Daniel T 2023. Paralog-specific signaling by IRAK1/4 maintains MyD88-independent functions in MDS/AML. Blood, , Dean, Sarai T; Ishikawa, Chiharu; Zhu, Xiaoqin; Walulik, Sean; Nixon, Timothy; Jordan, Jessica K; Henderson, Samantha; Wyder, Michael; Salomonis, Nathan; Wunderlich, Mark; Greis, Kenneth D; Starczynowski, Daniel T; Volk, Andrew G 2023. Repression of TRIM13 by chromatin assembly factor CHAF1B is critical for AML development. Blood advances, , Uehara, Yasuaki; Tanaka, Yusuke; Zhao, Shuyang; Nikolaidis, Nikolaos M; Pitstick, Lori B; Wu, Huixing; Yu, Jane J; Zhang, Erik; Hasegawa, Yoshihiro; Noel, John G; Gardner, Jason C; Kopras, Elizabeth J; Haffey, Wendy D; Greis, Kenneth D; Guo, Jinbang; Woods, Jason C; Wikenheiser-Brokamp, Kathryn A; Kyle, Jennifer E; Ansong, Charles; Teitelbaum, Steven L; Inoue, Yoshikazu; Altinişik, Göksel; Xu, Yan; McCormack, Francis X 2023. Insights into pulmonary phosphate homeostasis and osteoclastogenesis emerge from the study of pulmonary alveolar microlithiasis. Nature communications, 14 1, 1205Barreyro, Laura; Sampson, Avery M; Ishikawa, Chiharu; Hueneman, Kathleen M; Choi, Kwangmin; Pujato, Mario A; Chutipongtanate, Somchai; Wyder, Michael; Haffey, Wendy D; O'Brien, Eric; Wunderlich, Mark; Ramesh, Vighnesh; Kolb, Ellen M; Meydan, Cem; Neelamraju, Yaseswini; Bolanos, Lyndsey C; Christie, Susanne; Smith, Molly A; Niederkorn, Madeline; Muto, Tomoya; Kesari, Santosh; Garrett-Bakelman, Francine E; Bartholdy, Boris; Will, Britta; Weirauch, Matthew T; Mulloy, James C; Gul, Zartash; Medlin, Stephen; Kovall, Rhett A; Melnick, Ari M; Perentesis, John P; Greis, Kenneth D; Nurmemmedov, Elmar; Seibel, William L; Starczynowski, Daniel T 2022. Blocking UBE2N abrogates oncogenic immune signaling in acute myeloid leukemia. Science translational medicine, 14 635, eabb7695Crowther, Rebecca R; Schmidt, Stephanie M; Lange, Shannon M; McKell, Melanie C; Robillard, Michelle C; Zhao, Junfang; Haffey, Wendy D; Wyder, Michael A; Greis, Kenneth D; Setchell, Kenneth D R; Qualls, Joseph E 2022. Cutting Edge: l-Arginine Transfer from Antigen-Presenting Cells Sustains CD4+ T Cell Viability and Proliferation. Journal of immunology (Baltimore, Md. : 1950), 208 4, 793-798Curry, Erin; Philpott, Megan E; Wojtusik, Jessye; Haffey, Wendy D; Wyder, Michael A; Greis, Kenneth D; Roth, Terri L 2022. Label-Free Quantification (LFQ) of Fecal Proteins for Potential Pregnancy Detection in Polar Bears. Life (Basel, Switzerland), 12 6, Kirley, Terence L; Greis, Kenneth D; Norman, Andrew B 2022. Tyrosine nitration of a humanized anti-cocaine mAb differentially affects ligand binding of cocaine and its metabolites. Biochemistry and biophysics reports, 30 , 101278Kirley, Terence L; Norman, Andrew B; Greis, Kenneth D 2022. Oxidation of specific tryptophan residues inhibits high affinity binding of cocaine and its metabolites to a humanized anti-cocaine mAb. The Journal of biological chemistry, , 101689Muto, Tomoya; Guillamot, Maria; Yeung, Jennifer; Fang, Jing; Bennett, Joshua; Nadorp, Bettina; Lasry, Audrey; Redondo, Luna Zea; Choi, Kwangmin; Gong, Yixiao; Walker, Callum S; Hueneman, Kathleen; Bolanos, Lyndsey C; Barreyro, Laura; Lee, Lynn H; Greis, Kenneth D; Vasyliev, Nikita; Khodadadi-Jamayran, Alireza; Nudler, Evgeny; Lujambio, Amaia; Lowe, Scott W; Aifantis, Iannis; Starczynowski, Daniel T 2022. TRAF6 functions as a tumor suppressor in myeloid malignancies by directly targeting MYC oncogenic activity. Cell stem cell, , Davis, Harold W; Vallabhapurapu, Subrahmanya D; Chu, Zhengtao; Wyder, Michael A; Greis, Kenneth D; Fannin, Venette; Sun, Ying; Desai, Pankaj B; Pak, Koon Y; Gray, Brian D; Qi, Xiaoyang 2020. Biotherapy of Brain Tumors with Phosphatidylserine-Targeted Radioiodinated SapC-DOPS Nanovesicles. Cells, 9 9, Dwivedi, Pankaj; Chutipongtanate, Somchai; Muench, David E; Azam, Mohammad; Grimes, H Leighton; Greis, Kenneth D 2020. SWATH-Proteomics of Ibrutinib's Action in Myeloid Leukemia Initiating Mutated G-CSFR Signaling. Proteomics. Clinical applications, , e1900144He, Quan; Wang, Fangfei; Honda, Takashi; Greis, Kenneth D; Redington, Andrew N 2020. Ablation of miR-144 increases vimentin expression and atherosclerotic plaque formation. Scientific reports, 10 1, 6127Huang, Huilin; Weng, Hengyou; Sun, Wenju; Qin, Xi; Shi, Hailing; Wu, Huizhe; Zhao, Boxuan Simen; Mesquita, Ana; Liu, Chang; Yuan, Celvie L; Hu, Yueh-Chiang; Hüttelmaier, Stefan; Skibbe, Jennifer R; Su, Rui; Deng, Xiaolan; Dong, Lei; Sun, Miao; Li, Chenying; Nachtergaele, Sigrid; Wang, Yungui; Hu, Chao; Ferchen, Kyle; Greis, Kenneth D; Jiang, Xi; Wei, Minjie; Qu, Lianghu; Guan, Jun-Lin; He, Chuan; Yang, Jianhua; Chen, Jianjun 2020. Publisher Correction: Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation. Nature cell biology, 22 10, 1288Manning, Janet R; Wijeratne, Aruna B; Oloizia, Brian B; Zhang, Yu; Greis, Kenneth D; Schultz, Jo El J 2020. Phosphoproteomic analysis identifies phospho-Threonine-17 site of phospholamban important in low molecular weight isoform of fibroblast growth factor 2-induced protection against post-ischemic cardiac dysfunction. Journal of molecular and cellular cardiology, 148 , 1-14Muench, David E; Olsson, Andre; Ferchen, Kyle; Pham, Giang; Serafin, Rachel A; Chutipongtanate, Somchai; Dwivedi, Pankaj; Song, Baobao; Hay, Stuart; Chetal, Kashish; Trump-Durbin, Lisa R; Mookerjee-Basu, Jayati; Zhang, Kejian; Yu, Jennifer C; Lutzko, Carolyn; Myers, Kasiani C; Nazor, Kristopher L; Greis, Kenneth D; Kappes, Dietmar J; Way, Sing Sing; Salomonis, Nathan; Grimes, H Leighton 2020. Mouse models of neutropenia reveal progenitor-stage-specific defects. Nature, 582 7810, 109-114Niederkorn, Madeline; Hueneman, Kathleen; Choi, Kwangmin; Varney, Melinda E; Romano, Laurel; Pujato, Mario A; Greis, Kenneth D; Inoue, Jun-Ichiro; Meetei, Ruhikanta; Starczynowski, Daniel T 2020. TIFAB Regulates USP15-Mediated p53 Signaling during Stressed and Malignant Hematopoiesis. Cell reports, 30 8, 2776-2790.e6Schieber, Michael; Marinaccio, Christian; Bolanos, Lyndsey C; Haffey, Wendy D; Greis, Kenneth D; Starczynowski, Daniel T; Crispino, John D 2020. FBXO11 is a candidate tumor suppressor in the leukemic transformation of myelodysplastic syndrome. Blood cancer journal, 10 10, 98Dwivedi, Pankaj; Muench, David E; Wagner, Michael; Azam, Mohammad; Grimes, H Leighton; Greis, Kenneth D 2019. Phospho serine and threonine analysis of normal and mutated granulocyte colony stimulating factor receptors. Scientific data, 6 1, 21Forster, Catherine S; Haffey, Wendy D; Bennett, Michael; Greis, Kenneth D; Devarajan, Prasad 2019. Identification of Urinary CD44 and Prosaposin as Specific Biomarkers of Urinary Tract Infections in Children With Neurogenic Bladders. Biomarker insights, 14 , 1177271919835570Turnier JL, Brunner HI, Bennett M, Aleed A, Gulati G, Haffey WD, Thornton S, Wagner M, Devarajan P, Witte D, Greis KD, Aronow B. 2019. Discovery of SERPINA3 as a candidate urinary biomarker of lupus nephritis activity Rheumatology, 58(2) , 321-330Chutipongtanate, Somchai; Greis, Kenneth D 2018. Multiplex Biomarker Screening Assay for Urinary Extracellular Vesicles Study: A Targeted Label-Free Proteomic Approach. Scientific reports, 8 1, 15039Dwivedi, Pankaj; Muench, David E; Wagner, Michael; Azam, Mohammad; Grimes, H Leighton; Greis, Kenneth D 2018. Time resolved quantitative phospho-tyrosine analysis reveals Bruton's Tyrosine kinase mediated signaling downstream of the mutated granulocyte-colony stimulating factor receptors. Leukemia, , Huang, Huilin; Weng, Hengyou; Sun, Wenju; Qin, Xi; Shi, Hailing; Wu, Huizhe; Zhao, Boxuan Simen; Mesquita, Ana; Liu, Chang; Yuan, Celvie L; Hu, Yueh-Chiang; Hüttelmaier, Stefan; Skibbe, Jennifer R; Su, Rui; Deng, Xiaolan; Dong, Lei; Sun, Miao; Li, Chenying; Nachtergaele, Sigrid; Wang, Yungui; Hu, Chao; Ferchen, Kyle; Greis, Kenneth D; Jiang, Xi; Wei, Minjie; Qu, Lianghu; Guan, Jun-Lin; He, Chuan; Yang, Jianhua; Chen, Jianjun 2018. Author Correction: Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation. Nature cell biology, 20 9, 1098Huang, Huilin; Weng, Hengyou; Sun, Wenju; Qin, Xi; Shi, Hailing; Wu, Huizhe; Zhao, Boxuan Simen; Mesquita, Ana; Liu, Chang; Yuan, Celvie L; Hu, Yueh-Chiang; Hüttelmaier, Stefan; Skibbe, Jennifer R; Su, Rui; Deng, Xiaolan; Dong, Lei; Sun, Miao; Li, Chenying; Nachtergaele, Sigrid; Wang, Yungui; Hu, Chao; Ferchen, Kyle; Greis, Kenneth D; Jiang, Xi; Wei, Minjie; Qu, Lianghu; Guan, Jun-Lin; He, Chuan; Yang, Jianhua; Chen, Jianjun 2018. Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation. Nature cell biology, 20 3, 285-295Kirley, Terence L; Greis, Kenneth D; Norman, Andrew B 2018. Domain unfolding of monoclonal antibody fragments revealed by non-reducing SDS-PAGE. Biochemistry and biophysics reports, 16 , 138-144Smith, Eric A; Krumpelbeck, Eric F; Jegga, Anil G; Prell, Malte; Matrka, Marie M; Kappes, Ferdinand; Greis, Kenneth D; Ali, Abdullah M; Meetei, Amom R; Wells, Susanne I 2018. The nuclear DEK interactome supports multi-functionality. Proteins, 86 1, 88-97Turnier, Jessica L; Brunner, Hermine I; Bennett, Michael; Aleed, Ashwaq; Gulati, Gaurav; Haffey, Wendy D; Thornton, Sherry; Wagner, Michael; Devarajan, Prasad; Witte, David; Greis, Kenneth D; Aronow, Bruce 2018. Discovery of SERPINA3 as a candidate urinary biomarker of lupus nephritis activity. Rheumatology (Oxford, England), , Yuan, Long; Mishra, Rosalin; Patel, Hima; Abdulsalam, Safnas; Greis, Kenneth D; Kadekaro, Ana Luisa; Merino, Edward J; Garrett, Joan T 2018. Utilization of Reactive Oxygen Species Targeted Therapy to Prolong the Efficacy of BRAF Inhibitors in Melanoma. Journal of Cancer, 9 24, 4665-4676Bennett, Michael R; Pleasant, LaTawnya; Haffner, Christopher; Ma, Qing; Haffey, Wendy D; Ying, Jun; Wagner, Michael; Greis, Kenneth D; Devarajan, Prasad 2017. A Novel Biomarker Panel to Identify Steroid Resistance in Childhood Idiopathic Nephrotic Syndrome. Biomarker insights, 12 , 1177271917695832Dwivedi, Pankaj; Greis, Kenneth D 2017. Granulocyte colony-stimulating factor receptor signaling in severe congenital neutropenia, chronic neutrophilic leukemia, and related malignancies. Experimental hematology, 46 , 9-20Fang, Jing; Bolanos, Lyndsey C; Choi, Kwangmin; Liu, Xiaona; Christie, Susanne; Akunuru, Shailaja; Kumar, Rupali; Wang, Dehua; Chen, Xiaoting; Greis, Kenneth D; Stoilov, Peter; Filippi, Marie-Dominique; Maciejewski, Jaroslaw P; Garcia-Manero, Guillermo; Weirauch, Matthew T; Salamonis, Nathan; Geiger, Hartmut; Zheng, Yi; Starczynowski, Daniel T 2017. Corrigendum: Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia. Nature immunology, 18 4, 474Fang, Jing; Bolanos, Lyndsey C; Choi, Kwangmin; Liu, Xiaona; Christie, Susanne; Akunuru, Shailaja; Kumar, Rupali; Wang, Dehua; Chen, Xiaoting; Greis, Kenneth D; Stoilov, Peter; Filippi, Marie-Dominique; Maciejewski, Jaroslaw P; Garcia-Manero, Guillermo; Weirauch, Matthew T; Salomonis, Nathan; Geiger, Hartmut; Zheng, Yi; Starczynowski, Daniel T 2017. Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia. Nature immunology, 18 2, 236-245Blanco, Víctor M; Chu, Zhengtao; LaSance, Kathleen; Gray, Brian D; Yan Pak, Koon; Rider, Therese; Greis, Kenneth D; Qi, Xiaoyang 2016. Optical and nuclear imaging of glioblastoma with phosphatidylserine-targeted nanovesicles. Oncotarget, , Heaven, Michael R; Funk, Adam J; Cobbs, Archie L; Haffey, Wendy D; Norris, Jeremy L; McCullumsmith, Robert E; Greis, Kenneth D 2016. Systematic evaluation of data-independent acquisition for sensitive and reproducible proteomics-a prototype design for a single injection assay. Journal of mass spectrometry : JMS, 51 1, 1-11Kirley, Terence L; Greis, Kenneth D; Norman, Andrew B 2016. Selective disulfide reduction for labeling and enhancement of Fab antibody fragments. Biochemical and biophysical research communications, 480 4, 752-757Kirley, Terence L; Greis, Kenneth D; Norman, Andrew B 2016. Structural characterization of expressed monoclonal antibodies by single sample mass spectral analysis after IdeS proteolysis. Biochemical and biophysical research communications, 477 3, 363-8Sedlacek, Christopher J; Nielsen, Susanne; Greis, Kenneth D; Haffey, Wendy D; Revsbech, Niels Peter; Ticak, Tomislav; Laanbroek, Hendrikus J; Bollmann, Annette 2016. Effects of Bacterial Community Members on the Proteome of the Ammonia-Oxidizing Bacterium Nitrosomonas sp. Strain Is79. Applied and environmental microbiology, 82 15, 4776-88Hasegawa, Kazuteru; Sin, Ho-Su; Maezawa, So; Broering, Tyler J; Kartashov, Andrey V; Alavattam, Kris G; Ichijima, Yosuke; Zhang, Fan; Bacon, W Clark; Greis, Kenneth D; Andreassen, Paul R; Barski, Artem; Namekawa, Satoshi H 2015. SCML2 establishes the male germline epigenome through regulation of histone H2A ubiquitination. Developmental cell, 32 5, 574-88Huang, Yan; Powers, Corey; Madala, Satish K; Greis, Kenneth D; Haffey, Wendy D; Towbin, Jeffrey A; Purevjav, Enkhsaikhan; Javadov, Sabzali; Strauss, Arnold W; Khuchua, Zaza 2015. Cardiac metabolic pathways affected in the mouse model of barth syndrome. PloS one, 10 6, e0128561Huang,Y., Powers,C., Madala,S. K., Greis,K. D., Haffey,W. D., Towbin,J. A., Purevjav,E., Javadov,S., Strauss,A. W., Khuchua,Z. 2015. Cardiac metabolic pathways affected in the mouse model of barth syndrome PloS one, 10 6, e0128561Lu, Xiaoming; Zoller, Erin E; Weirauch, Matthew T; Wu, Zhiguo; Namjou, Bahram; Williams, Adrienne H; Ziegler, Julie T; Comeau, Mary E; Marion, Miranda C; Glenn, Stuart B; Adler, Adam; Shen, Nan; Nath, Swapan K; Stevens, Anne M; Freedman, Barry I; Tsao, Betty P; Jacob, Chaim O; Kamen, Diane L; Brown, Elizabeth E; Gilkeson, Gary S; Alarcón, Graciela S; Reveille, John D; Anaya, Juan-Manuel; James, Judith A; Sivils, Kathy L; Criswell, Lindsey A; Vilá, Luis M; Alarcón-Riquelme, Marta E; Petri, Michelle; Scofield, R Hal; Kimberly, Robert P; Ramsey-Goldman, Rosalind; Joo, Young Bin; Choi, Jeongim; Bae, Sang-Cheol; Boackle, Susan A; Graham, Deborah Cunninghame; Vyse, Timothy J; Guthridge, Joel M; Gaffney, Patrick M; Langefeld, Carl D; Kelly, Jennifer A; Greis, Kenneth D; Kaufman, Kenneth M; Harley, John B; Kottyan, Leah C 2015. Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression. American journal of human genetics, 96 5, 731-9Marsh, J M; Davis, M G; Flagler, M J; Sun, Y; Chaudhary, T; Mamak, M; McComb, D W; Williams, R E A; Greis, K D; Rubio, L; Coderch, L 2015. Advanced hair damage model from ultra-violet radiation in the presence of copper. International journal of cosmetic science, 37 5, 532-41Marsh,J. M., Davis,M. G., Flagler,M. J., Sun,Y., Chaudhary,T., Mamak,M., McComb,D. W., Williams,R. E., Greis,K. D., Rubio,L., Coderch,L. 2015. Advanced hair damage model from ultra-violet radiation in the presence of copper International Journal of Cosmetic Science, 37 5, 532-41Thowfeik, Fathima Shazna; AbdulSalam, Safnas F; Wunderlich, Mark; Wyder, Michael; Greis, Kenneth D; Kadekaro, Ana L; Mulloy, James C; Merino, Edward J 2015. A ROS-Activatable Agent Elicits Homologous Recombination DNA Repair and Synergizes with Pathway Compounds. Chembiochem : a European journal of chemical biology, 16 17, 2513-21Wijeratne, Aruna B; Wijesundera, Dharshana N; Paulose, Maggie; Ahiabu, Ivy Belinda; Chu, Wei-Kan; Varghese, Oomman K; Greis, Kenneth D 2015. Phosphopeptide separation using radially aligned titania nanotubes on titanium wire. ACS applied materials & interfaces, 7 21, 11155-64Wijeratne,A. B., Wijesundera,D. N., Paulose,M., Ahiabu,I. B., Chu,W. K., Varghese,O. K., Greis,K. D. 2015. Phosphopeptide separation using radially aligned titania nanotubes on titanium wire ACS applied materials & interfaces, 7 21, 11155Liou B.;Haffey W.;Greis K.;Grabowski G. 2014. The LIMP-2/SCARB2 binding motif on acid Beta-Glucosidase: Basic and applied implications for Gaucher disease and associated neurodegenerative diseases Journal of Biological Chemistry, 289 43, 30063-74Liou, Benjamin; Haffey, Wendy D; Greis, Kenneth D; Grabowski, Gregory A 2014. The LIMP-2/SCARB2 binding motif on acid ?-glucosidase: basic and applied implications for Gaucher disease and associated neurodegenerative diseases. The Journal of biological chemistry, 289 43, 30063-74Marsh, JM; Iveson, R; Flagler, MJ; Davis, MG; Newland, AB; Greis, KD; Sun, Y; Chaudhary, T; Aistrup, ER 2014. Role of copper in photochemical damage to hair International journal of cosmetic science, 36 1, 32-8Green, Julianne V; Orsborn, Kris I; Zhang, Minlu; Tan, Queenie K G; Greis, Kenneth D; Porollo, Alexey; Andes, David R; Long Lu, Jason; Hostetter, Margaret K 2013. Heparin-binding motifs and biofilm formation by Candida albicans. The Journal of infectious diseases, 208 10, 1695-704Wijeratne, Aruna B; Manning, Janet R; Schultz, Jo El J; Greis, Kenneth D 2013. Quantitative phosphoproteomics using acetone-based Peptide labeling: method evaluation and application to a cardiac ischemia/reperfusion model. Journal of proteome research, 12 10, 4268-79Gauthamadasa, Kekulawalage; Vaitinadin, Nataraja Sarma; Dressman, James L; Macha, Stephen; Homan, Reyn; Greis, Kenneth D; Silva, R A Gangani D 2012. Apolipoprotein A-II-mediated conformational changes of apolipoprotein A-I in discoidal high density lipoproteins. The Journal of biological chemistry, 287 10, 7615-25Govindan, Suresh; McElligott, Andrew; Muthusamy, Saminathan; Nair, Nandini; Barefield, David; Martin, Jody L; Gongora, Enrique; Greis, Kenneth D; Luther, Pradeep K; Winegrad, Saul; Henderson, Kyle K; Sadayappan, Sakthivel 2012. Cardiac myosin binding protein-C is a potential diagnostic biomarker for myocardial infarction. Journal of molecular and cellular cardiology, 52 1, 154-64Kattamuri, Chandramohan; Luedeke, David M; Nolan, Kristof; Rankin, Scott A; Greis, Kenneth D; Zorn, Aaron M; Thompson, Thomas B 2012. Members of the DAN family are BMP antagonists that form highly stable noncovalent dimers. Journal of molecular biology, 424 5, 313-27Djung, Jane F; Mears, Richard J; Montalbetti, Christian A G N; Coulter, Thomas S; Golebiowski, Adam; Carr, Andrew N; Barker, Oliver; Greis, Kenneth D; Zhou, Songtao; Dolan, Elizabeth; Davis, Gregory F 2011. The synthesis and evaluation of indolylureas as PKC? inhibitors. Bioorganic & medicinal chemistry, 19 8, 2742-50Linares J.;Amanchy R.;Greis K.;Diaz-Meco M.;Moscat J. 2011. Author's correction: Phosphorylation of p62 by cdk1 controls the timely transit of cells through mit Molecular and Cellular Biology, 31 10, 2171Linares, Juan F; Amanchy, Ramars; Greis, Kenneth; Diaz-Meco, Maria T; Moscat, Jorge 2011. Phosphorylation of p62 by cdk1 controls the timely transit of cells through mitosis and tumor cell proliferation. Molecular and cellular biology, 31 1, 105-17Myer, David L; Robbins, Susan B; Yin, Moying; Boivin, Gregory P; Liu, Yang; Greis, Kenneth D; Bahassi, El Mustapha; Stambrook, Peter J 2011. Absence of polo-like kinase 3 in mice stabilizes Cdc25A after DNA damage but is not sufficient to produce tumors. Mutation research, 714 1-2, 1-10Piyaphanee, Nuntawan; Ma, Qing; Kremen, Oran; Czech, Kimberly; Greis, Kenneth; Mitsnefes, Mark; Devarajan, Prasad; Bennett, Michael R 2011. Discovery and initial validation of ? 1-B glycoprotein fragmentation as a differential urinary biomarker in pediatric steroid-resistant nephrotic syndrome. Proteomics. Clinical applications, 5 5-6, 334-42Ridsdale, Ross; Na, Cheng-Lun; Xu, Yan; Greis, Kenneth D; Weaver, Timothy 2011. Comparative proteomic analysis of lung lamellar bodies and lysosome-related organelles. PloS one, 6 1, e16482Rathore, Rakesh; Pribil, Patrick; Corr, Jay J; Seibel, William L; Evdokimov, Artem; Greis, Kenneth D 2010. Multiplex Enzyme Assays and Inhibitor Screening by Mass Spectrometry. Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening, , Aslan, Joseph E; You, Huihong; Williamson, Danielle M; Endig, Jessica; Youker, Robert T; Thomas, Laurel; Shu, Hongjun; Du, Yuhong; Milewski, Robert L; Brush, Matthew H; Possemato, Anthony; Sprott, Kam; Fu, Haian; Greis, Kenneth D; Runckel, Douglas N; Vogel, Arndt; Thomas, Gary 2009. Akt and 14-3-3 control a PACS-2 homeostatic switch that integrates membrane traffic with TRAIL-induced apoptosis. Molecular cell, 34 4, 497-509Eismann, Thorsten; Huber, Nadine; Shin, Thomas; Kuboki, Satoshi; Galloway, Elizabeth; Wyder, Michael; Edwards, Michael J; Greis, Kenneth D; Shertzer, Howard G; Fisher, Aron B; Lentsch, Alex B 2009. Peroxiredoxin-6 protects against mitochondrial dysfunction and liver injury during ischemia-reperfusion in mice. American journal of physiology. Gastrointestinal and liver physiology, 296 2, G266-74Haffey, Wendy D; Mikhaylova, Olga; Meller, Jarek; Yi, Ying; Greis, Kenneth D; Czyzyk-Krzeska, Maria F 2009. iTRAQ proteomic identification of pVHL-dependent and -independent targets of Egln1 prolyl hydroxylase knockdown in renal carcinoma cells. Advances in enzyme regulation, 49 1, 121-32Rathore, Rakesh; Corr, Jay J; Lebre, Daniel T; Seibel, William L; Greis, Kenneth D 2009. Extending matrix-assisted laser desorption/ionization triple quadrupole mass spectrometry enzyme screening assays to targets with small molecule substrates. Rapid communications in mass spectrometry : RCM, 23 20, 3293-300Stella, Caroline L; Bennett, Michael R; Devarajan, Prasad; Greis, Kenneth; Wyder, Michael; Macha, Stephen; Rao, Marepalli; Jodicke, Cristiano; Moussa, Hind; How, Helen Y; Myatt, Leslie; Webster, Rose; Sibai, Baha M 2009. Preterm labor biomarker discovery in serum using 3 proteomic profiling methodologies. American journal of obstetrics and gynecology, 201 4, 387.e1-13Suzuki, Michiko; Wiers, Kristina; Brooks, Elizabeth B; Greis, Kenneth D; Haines, Kathleen; Klein-Gitelman, Marisa S; Olson, Judyann; Onel, Karen; O 2009. Initial validation of a novel protein biomarker panel for active pediatric lupus nephritis. Pediatric research, 65 5, 530-6Mikhaylova, Olga; Ignacak, Monika L; Barankiewicz, Teresa J; Harbaugh, Svetlana V; Yi, Ying; Maxwell, Patrick H; Schneider, Martin; Van Geyte, Katie; Carmeliet, Peter; Revelo, Monica P; Wyder, Michael; Greis, Kenneth D; Meller, Jarek; Czyzyk-Krzeska, Maria F 2008. The von Hippel-Lindau tumor suppressor protein and Egl-9-Type proline hydroxylases regulate the large subunit of RNA polymerase II in response to oxidative stress. Molecular and cellular biology, 28 8, 2701-17Rathore, Rakesh; Corr, Jay; Scott, George; Vollmerhaus, Pauline; Greis, Kenneth D 2008. Development of an inhibitor screening platform via mass spectrometry. Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening, 13 10, 1007-13Greis, Kenneth D 2007. Mass spectrometry for enzyme assays and inhibitor screening: an emerging application in pharmaceutical research. Mass spectrometry reviews, 26 3, 324-39Greis, Kenneth D; Zhou, Songtao; Burt, Thomas M; Carr, Andrew N; Dolan, Elizabeth; Easwaran, Vijayasurian; Evdokimov, Artem; Kawamoto, Richard; Roesgen, Jeff; Davis, Gregory F 2006. MALDI-TOF MS as a label-free approach to rapid inhibitor screening. Journal of the American Society for Mass Spectrometry, 17 6, 815-22Greis, Kenneth D; Zhou, Songtao; Siehnel, Richard; Klanke, Chuck; Curnow, Alan; Howard, Jeremy; Layh-Schmitt, Gerlinde 2005. Development and validation of a whole-cell inhibition assay for bacterial methionine aminopeptidase by surface-enhanced laser desorption ionization-time of flight mass spectrometry. Antimicrobial agents and chemotherapy, 49 8, 3428-34Jarrold, Bradley; DeMuth, Jeffrey; Greis, Kenneth; Burt, Thomas; Wang, Feng 2005. An effective skeletal muscle prefractionation method to remove abundant structural proteins for optimized two-dimensional gel electrophoresis Electrophoresis, 26 11, 2269-78Peters, Kevin G; Davis, Mike G; Howard, Brian W; Pokross, Matthew; Rastogi, Vinit; Diven, Conrad; Greis, Kenneth D; Eby-Wilkens, Elaine; Maier, Matthew; Evdokimov, Artem; Soper, Shari; Genbauffe, Frank 2003. Mechanism of insulin sensitization by BMOV (bis maltolato oxo vanadium); unliganded vanadium (VO4) as the active component. Journal of inorganic biochemistry, 96 2-3, 321-30Thompson, Larry J; Wang, Feng; Proia, Alan D; Peters, Kevin G; Jarrold, Brad; Greis, Kenneth D 2003. Proteome analysis of the rat cornea during angiogenesis. Proteomics, 3 11, 2258-66Delinsky, David C; Greis, Kenneth D 2002. Capillary chromatography-coupled mass spectrometry with column switching for rapid identification of proteins from 2-dimensional electrophoresis gels. Journal of proteome research, 1 3, 279-84Isfort, Robert J; Wang, Feng; Greis, Kenneth D; Sun, Yiping; Keough, Thomas W; Bodine, Sue C; Anderson, N Leigh 2002. Proteomic analysis of rat soleus and tibialis anterior muscle following immobilization. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 769 2, 323-32Isfort, Robert J; Wang, Feng; Greis, Kenneth D; Sun, Yiping; Keough, Thomas W; Farrar, Roger P; Bodine, Sue C; Anderson, N Leigh 2002. Proteomic analysis of rat soleus muscle undergoing hindlimb suspension-induced atrophy and reweighting hypertrophy. Proteomics, 2 5, 543-50Egnaczyk, G F; Greis, K D; Stimson, E R; Maggio, J E 2001. Photoaffinity cross-linking of Alzheimer's disease amyloid fibrils reveals interstrand contact regions between assembled beta-amyloid peptide subunits. Biochemistry, 40 39, 11706-14Hoke S.;Morand K.;Greis K.;Baker T.;Harbol K.;Dobson R. 2001. Transformations in pharmaceutical research and development, driven by innovations in multidimensiona International Journal of Mass Spectrometry, 212 1-3, 135-196Isfort, R J; Hinkle, R T; Jones, M B; Wang, F; Greis, K D; Sun, Y; Keough, T W; Anderson, N L; Sheldon, R J 2000. Proteomic analysis of the atrophying rat soleus muscle following denervation. Electrophoresis, 21 11, 2228-34Sanchez, V; Greis, K D; Sztul, E; Britt, W J 2000. Accumulation of virion tegument and envelope proteins in a stable cytoplasmic compartment during human cytomegalovirus replication: characterization of a potential site of virus assembly. Journal of virology, 74 2, 975-86Smaill, ; Rewcastle, ; Loo, ; Greis, ; Chan, ; Reyner, ; Lipka, ; Showalter, ; Vincent, ; Elliott, ; Denny, 2000. Tyrosine kinase inhibitors. 17. Irreversible inhibitors of the epidermal growth factor receptor: 4-(Phenylamino)quinazoline- and 4-(Phenylamino)pyrido Journal of medicinal chemistry, 43 16, 3199Smaill, J B; Rewcastle, G W; Loo, J A; Greis, K D; Chan, O H; Reyner, E L; Lipka, E; Showalter, H D; Vincent, P W; Elliott, W L; Denny, W A 2000. Tyrosine kinase inhibitors. 17. Irreversible inhibitors of the epidermal growth factor receptor: 4-(phenylamino)quinazoline- and 4-(phenylamino)pyrido[3,2-d]pyrimidine-6-acrylamides bearing additional solubilizing functions. Journal of medicinal chemistry, 43 7, 1380-97VanBogelen, R A; Greis, K D; Blumenthal, R M; Tani, T H; Matthews, R G 1999. Mapping regulatory networks in microbial cells. Trends in microbiology, 7 8, 320-8Fry, D W; Bridges, A J; Denny, W A; Doherty, A; Greis, K D; Hicks, J L; Hook, K E; Keller, P R; Leopold, W R; Loo, J A; McNamara, D J; Nelson, J M; Sherwood, V; Smaill, J B; Trumpp-Kallmeyer, S; Dobrusin, E M 1998. Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor. Proceedings of the National Academy of Sciences of the United States of America, 95 20, 12022-7Greis, K D; Hart, G W 1998. Analytical methods for the study of O-GlcNAc glycoproteins and glycopeptides. Methods in molecular biology (Clifton, N.J.), 76 , 19-33Stevenson, T I; Loo, J A; Greis, K D 1998. Coupling capillary high-performance liquid chromatography to matrix-assisted laser desorption/ionization mass spectrometry and N-terminal sequencing of peptides via automated microblotting onto membrane substrates. Analytical biochemistry, 262 2, 99-109Greis K.D.;Hart G.W. 1997. Chapter 2 Nuclear and Cytoplasmic Glycoproteins New Comprehensive Biochemistry, 29 PART B, 33-54Greis, K D; Hayes, B K; Comer, F I; Kirk, M; Barnes, S; Lowary, T L; Hart, G W 1996. Selective detection and site-analysis of O-GlcNAc-modified glycopeptides by beta-elimination and tandem electrospray mass spectrometry. Analytical biochemistry, 234 1, 38-49Greis, K D; Zhu, S; Matalon, S 1996. Identification of nitration sites on surfactant protein A by tandem electrospray mass spectrometry. Archives of biochemistry and biophysics, 335 2, 396-402Hart G.W.;Greis K.D.;Dong L.Y.D.;Blomberg M.A.;Chou T.Y.;Jiang M.S.;Roquemore E.P.;Snow D.M.;Kreppel L.K.;Cole R.C.;Hayes B.K. 1995. Ubiquitous and temporal glycosylation of nuclear and cytoplasmic proteins Pure and Applied Chemistry, 67 10, 1637-1645Hart, G W; Greis, K D; Dong, L Y; Blomberg, M A; Chou, T Y; Jiang, M S; Roquemore, E P; Snow, D M; Kreppel, L K; Cole, R N 1995. O-linked N-acetylglucosamine: the "yin-yang" of Ser/Thr phosphorylation? Nuclear and cytoplasmic glycosylation. Advances in experimental medicine and biology, 376 , 115-23Hayes, B K; Greis, K D; Hart, G W 1995. Specific isolation of O-linked N-acetylglucosamine glycopeptides from complex mixtures. Analytical biochemistry, 228 1, 115-22Greis, K D; Gibson, W; Hart, G W 1994. Site-specific glycosylation of the human cytomegalovirus tegument basic phosphoprotein (UL32) at serine 921 and serine 952. Journal of virology, 68 12, 8339-49Greis, K D; Turco, S J; Thomas, J R; McConville, M J; Homans, S W; Ferguson, M A 1992. Purification and characterization of an extracellular phosphoglycan from Leishmania donovani. The Journal of biological chemistry, 267 9, 5876-81Thomas, J R; McConville, M J; Thomas-Oates, J E; Homans, S W; Ferguson, M A; Gorin, P A; Greis, K D; Turco, S J 1992. Refined structure of the lipophosphoglycan of Leishmania donovani. The Journal of biological chemistry, 267 10, 6829-33Crawford, I T; Greis, K D; Parks, L; Streips, U N 1987. Facile autoplast generation and transformation in Bacillus thuringiensis subsp. kurstaki. Journal of bacteriology, 169 12, 5423-8 Kirley T.L.; Greis K.D.; Norman A.B. 12-01-2018. Domain unfolding of monoclonal antibody fragments revealed by non-reducing SDS-PAGE Biochemistry and Biophysics Reports, 16 , 138-144 Jarrold B.; DeMuth J.; Greis K.; Burt T.; Wang F. 12-01-2005. An effective skeletal muscle prefractionation method to remove abundant structural proteins for opti AIChE Annual Meeting, Conference Proceedings, , 12387-12396 Delinsky D.; Greis K. 12-01-2002. Rapid capillary LC-ESI-MS/MS via column switching for proteomics applications Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics, , 155-156 Linares J.; Amanchy R.; Greis K.; Diaz-Meco M.; Moscat J. 08-01-2017. Correction: "Phosphorylation of p62 by cdk1 controls the timely transit of cells through mitosis and Molecular and Cellular Biology, 37 15, Bennett M.R.; Pleasant L.T.; Haffner C.; Ma Q.; Haffey W.D.; Ying J.; Wagner M.; Greis K.D.; Devarajan P. 03-08-2017. A novel biomarker panel to identify steroid resistance in childhood idiopathic nephrotic syndrome Biomarker Insights, 12 , Forster C.; Haffey W.; Bennett M.; Greis K.; Devarajan P. 03-01-2019. Identification of Urinary CD44 and Prosaposin as Specific Biomarkers of Urinary Tract Infections in Biomarker Insights, 14 , Yuan L.; Mishra R.; Patel H.; Abdulsalam S.; Greis K.; Kadekaro A.; Merino E.; Garrett J. 01-01-2018. Utilization of reactive oxygen species targeted therapy to prolong the efficacy of braf inhibitors i Journal of Cancer, 9 24, 4665-4676
Bennett, Joshua Ruina; Ishikawa, Chiharu; Agarwal, Puneet; Yeung, Jennifer; Sampson, Avery; Uible, Emma; Vick, Eric; Bolanos, Lyndsey; Hueneman, Kathleen M; Wunderlich, Mark; Kolt, Amal; Choi, Kwangmin; Volk, Andrew G; Greis, Kenneth D; Rosenbaum, Jan S; Hoyt, Scott; Thomas, Craig J; Starczynowski, Daniel T 2023. Paralog-specific signaling by IRAK1/4 maintains MyD88-independent functions in MDS/AML. Blood, , Dean, Sarai T; Ishikawa, Chiharu; Zhu, Xiaoqin; Walulik, Sean; Nixon, Timothy; Jordan, Jessica K; Henderson, Samantha; Wyder, Michael; Salomonis, Nathan; Wunderlich, Mark; Greis, Kenneth D; Starczynowski, Daniel T; Volk, Andrew G 2023. Repression of TRIM13 by chromatin assembly factor CHAF1B is critical for AML development. Blood advances, , Uehara, Yasuaki; Tanaka, Yusuke; Zhao, Shuyang; Nikolaidis, Nikolaos M; Pitstick, Lori B; Wu, Huixing; Yu, Jane J; Zhang, Erik; Hasegawa, Yoshihiro; Noel, John G; Gardner, Jason C; Kopras, Elizabeth J; Haffey, Wendy D; Greis, Kenneth D; Guo, Jinbang; Woods, Jason C; Wikenheiser-Brokamp, Kathryn A; Kyle, Jennifer E; Ansong, Charles; Teitelbaum, Steven L; Inoue, Yoshikazu; Altinişik, Göksel; Xu, Yan; McCormack, Francis X 2023. Insights into pulmonary phosphate homeostasis and osteoclastogenesis emerge from the study of pulmonary alveolar microlithiasis. Nature communications, 14 1, 1205Barreyro, Laura; Sampson, Avery M; Ishikawa, Chiharu; Hueneman, Kathleen M; Choi, Kwangmin; Pujato, Mario A; Chutipongtanate, Somchai; Wyder, Michael; Haffey, Wendy D; O'Brien, Eric; Wunderlich, Mark; Ramesh, Vighnesh; Kolb, Ellen M; Meydan, Cem; Neelamraju, Yaseswini; Bolanos, Lyndsey C; Christie, Susanne; Smith, Molly A; Niederkorn, Madeline; Muto, Tomoya; Kesari, Santosh; Garrett-Bakelman, Francine E; Bartholdy, Boris; Will, Britta; Weirauch, Matthew T; Mulloy, James C; Gul, Zartash; Medlin, Stephen; Kovall, Rhett A; Melnick, Ari M; Perentesis, John P; Greis, Kenneth D; Nurmemmedov, Elmar; Seibel, William L; Starczynowski, Daniel T 2022. Blocking UBE2N abrogates oncogenic immune signaling in acute myeloid leukemia. Science translational medicine, 14 635, eabb7695Crowther, Rebecca R; Schmidt, Stephanie M; Lange, Shannon M; McKell, Melanie C; Robillard, Michelle C; Zhao, Junfang; Haffey, Wendy D; Wyder, Michael A; Greis, Kenneth D; Setchell, Kenneth D R; Qualls, Joseph E 2022. Cutting Edge: l-Arginine Transfer from Antigen-Presenting Cells Sustains CD4+ T Cell Viability and Proliferation. Journal of immunology (Baltimore, Md. : 1950), 208 4, 793-798Curry, Erin; Philpott, Megan E; Wojtusik, Jessye; Haffey, Wendy D; Wyder, Michael A; Greis, Kenneth D; Roth, Terri L 2022. Label-Free Quantification (LFQ) of Fecal Proteins for Potential Pregnancy Detection in Polar Bears. Life (Basel, Switzerland), 12 6, Kirley, Terence L; Greis, Kenneth D; Norman, Andrew B 2022. Tyrosine nitration of a humanized anti-cocaine mAb differentially affects ligand binding of cocaine and its metabolites. Biochemistry and biophysics reports, 30 , 101278Kirley, Terence L; Norman, Andrew B; Greis, Kenneth D 2022. Oxidation of specific tryptophan residues inhibits high affinity binding of cocaine and its metabolites to a humanized anti-cocaine mAb. The Journal of biological chemistry, , 101689Muto, Tomoya; Guillamot, Maria; Yeung, Jennifer; Fang, Jing; Bennett, Joshua; Nadorp, Bettina; Lasry, Audrey; Redondo, Luna Zea; Choi, Kwangmin; Gong, Yixiao; Walker, Callum S; Hueneman, Kathleen; Bolanos, Lyndsey C; Barreyro, Laura; Lee, Lynn H; Greis, Kenneth D; Vasyliev, Nikita; Khodadadi-Jamayran, Alireza; Nudler, Evgeny; Lujambio, Amaia; Lowe, Scott W; Aifantis, Iannis; Starczynowski, Daniel T 2022. TRAF6 functions as a tumor suppressor in myeloid malignancies by directly targeting MYC oncogenic activity. Cell stem cell, , Davis, Harold W; Vallabhapurapu, Subrahmanya D; Chu, Zhengtao; Wyder, Michael A; Greis, Kenneth D; Fannin, Venette; Sun, Ying; Desai, Pankaj B; Pak, Koon Y; Gray, Brian D; Qi, Xiaoyang 2020. Biotherapy of Brain Tumors with Phosphatidylserine-Targeted Radioiodinated SapC-DOPS Nanovesicles. Cells, 9 9, Dwivedi, Pankaj; Chutipongtanate, Somchai; Muench, David E; Azam, Mohammad; Grimes, H Leighton; Greis, Kenneth D 2020. SWATH-Proteomics of Ibrutinib's Action in Myeloid Leukemia Initiating Mutated G-CSFR Signaling. Proteomics. Clinical applications, , e1900144He, Quan; Wang, Fangfei; Honda, Takashi; Greis, Kenneth D; Redington, Andrew N 2020. Ablation of miR-144 increases vimentin expression and atherosclerotic plaque formation. Scientific reports, 10 1, 6127Huang, Huilin; Weng, Hengyou; Sun, Wenju; Qin, Xi; Shi, Hailing; Wu, Huizhe; Zhao, Boxuan Simen; Mesquita, Ana; Liu, Chang; Yuan, Celvie L; Hu, Yueh-Chiang; Hüttelmaier, Stefan; Skibbe, Jennifer R; Su, Rui; Deng, Xiaolan; Dong, Lei; Sun, Miao; Li, Chenying; Nachtergaele, Sigrid; Wang, Yungui; Hu, Chao; Ferchen, Kyle; Greis, Kenneth D; Jiang, Xi; Wei, Minjie; Qu, Lianghu; Guan, Jun-Lin; He, Chuan; Yang, Jianhua; Chen, Jianjun 2020. Publisher Correction: Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation. Nature cell biology, 22 10, 1288Manning, Janet R; Wijeratne, Aruna B; Oloizia, Brian B; Zhang, Yu; Greis, Kenneth D; Schultz, Jo El J 2020. Phosphoproteomic analysis identifies phospho-Threonine-17 site of phospholamban important in low molecular weight isoform of fibroblast growth factor 2-induced protection against post-ischemic cardiac dysfunction. Journal of molecular and cellular cardiology, 148 , 1-14Muench, David E; Olsson, Andre; Ferchen, Kyle; Pham, Giang; Serafin, Rachel A; Chutipongtanate, Somchai; Dwivedi, Pankaj; Song, Baobao; Hay, Stuart; Chetal, Kashish; Trump-Durbin, Lisa R; Mookerjee-Basu, Jayati; Zhang, Kejian; Yu, Jennifer C; Lutzko, Carolyn; Myers, Kasiani C; Nazor, Kristopher L; Greis, Kenneth D; Kappes, Dietmar J; Way, Sing Sing; Salomonis, Nathan; Grimes, H Leighton 2020. Mouse models of neutropenia reveal progenitor-stage-specific defects. Nature, 582 7810, 109-114Niederkorn, Madeline; Hueneman, Kathleen; Choi, Kwangmin; Varney, Melinda E; Romano, Laurel; Pujato, Mario A; Greis, Kenneth D; Inoue, Jun-Ichiro; Meetei, Ruhikanta; Starczynowski, Daniel T 2020. TIFAB Regulates USP15-Mediated p53 Signaling during Stressed and Malignant Hematopoiesis. Cell reports, 30 8, 2776-2790.e6Schieber, Michael; Marinaccio, Christian; Bolanos, Lyndsey C; Haffey, Wendy D; Greis, Kenneth D; Starczynowski, Daniel T; Crispino, John D 2020. FBXO11 is a candidate tumor suppressor in the leukemic transformation of myelodysplastic syndrome. Blood cancer journal, 10 10, 98Dwivedi, Pankaj; Muench, David E; Wagner, Michael; Azam, Mohammad; Grimes, H Leighton; Greis, Kenneth D 2019. Phospho serine and threonine analysis of normal and mutated granulocyte colony stimulating factor receptors. Scientific data, 6 1, 21Forster, Catherine S; Haffey, Wendy D; Bennett, Michael; Greis, Kenneth D; Devarajan, Prasad 2019. Identification of Urinary CD44 and Prosaposin as Specific Biomarkers of Urinary Tract Infections in Children With Neurogenic Bladders. Biomarker insights, 14 , 1177271919835570Turnier JL, Brunner HI, Bennett M, Aleed A, Gulati G, Haffey WD, Thornton S, Wagner M, Devarajan P, Witte D, Greis KD, Aronow B. 2019. Discovery of SERPINA3 as a candidate urinary biomarker of lupus nephritis activity Rheumatology, 58(2) , 321-330Chutipongtanate, Somchai; Greis, Kenneth D 2018. Multiplex Biomarker Screening Assay for Urinary Extracellular Vesicles Study: A Targeted Label-Free Proteomic Approach. Scientific reports, 8 1, 15039Dwivedi, Pankaj; Muench, David E; Wagner, Michael; Azam, Mohammad; Grimes, H Leighton; Greis, Kenneth D 2018. Time resolved quantitative phospho-tyrosine analysis reveals Bruton's Tyrosine kinase mediated signaling downstream of the mutated granulocyte-colony stimulating factor receptors. Leukemia, , Huang, Huilin; Weng, Hengyou; Sun, Wenju; Qin, Xi; Shi, Hailing; Wu, Huizhe; Zhao, Boxuan Simen; Mesquita, Ana; Liu, Chang; Yuan, Celvie L; Hu, Yueh-Chiang; Hüttelmaier, Stefan; Skibbe, Jennifer R; Su, Rui; Deng, Xiaolan; Dong, Lei; Sun, Miao; Li, Chenying; Nachtergaele, Sigrid; Wang, Yungui; Hu, Chao; Ferchen, Kyle; Greis, Kenneth D; Jiang, Xi; Wei, Minjie; Qu, Lianghu; Guan, Jun-Lin; He, Chuan; Yang, Jianhua; Chen, Jianjun 2018. Author Correction: Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation. Nature cell biology, 20 9, 1098Huang, Huilin; Weng, Hengyou; Sun, Wenju; Qin, Xi; Shi, Hailing; Wu, Huizhe; Zhao, Boxuan Simen; Mesquita, Ana; Liu, Chang; Yuan, Celvie L; Hu, Yueh-Chiang; Hüttelmaier, Stefan; Skibbe, Jennifer R; Su, Rui; Deng, Xiaolan; Dong, Lei; Sun, Miao; Li, Chenying; Nachtergaele, Sigrid; Wang, Yungui; Hu, Chao; Ferchen, Kyle; Greis, Kenneth D; Jiang, Xi; Wei, Minjie; Qu, Lianghu; Guan, Jun-Lin; He, Chuan; Yang, Jianhua; Chen, Jianjun 2018. Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation. Nature cell biology, 20 3, 285-295Kirley, Terence L; Greis, Kenneth D; Norman, Andrew B 2018. Domain unfolding of monoclonal antibody fragments revealed by non-reducing SDS-PAGE. Biochemistry and biophysics reports, 16 , 138-144Smith, Eric A; Krumpelbeck, Eric F; Jegga, Anil G; Prell, Malte; Matrka, Marie M; Kappes, Ferdinand; Greis, Kenneth D; Ali, Abdullah M; Meetei, Amom R; Wells, Susanne I 2018. The nuclear DEK interactome supports multi-functionality. Proteins, 86 1, 88-97Turnier, Jessica L; Brunner, Hermine I; Bennett, Michael; Aleed, Ashwaq; Gulati, Gaurav; Haffey, Wendy D; Thornton, Sherry; Wagner, Michael; Devarajan, Prasad; Witte, David; Greis, Kenneth D; Aronow, Bruce 2018. Discovery of SERPINA3 as a candidate urinary biomarker of lupus nephritis activity. Rheumatology (Oxford, England), , Yuan, Long; Mishra, Rosalin; Patel, Hima; Abdulsalam, Safnas; Greis, Kenneth D; Kadekaro, Ana Luisa; Merino, Edward J; Garrett, Joan T 2018. Utilization of Reactive Oxygen Species Targeted Therapy to Prolong the Efficacy of BRAF Inhibitors in Melanoma. Journal of Cancer, 9 24, 4665-4676Bennett, Michael R; Pleasant, LaTawnya; Haffner, Christopher; Ma, Qing; Haffey, Wendy D; Ying, Jun; Wagner, Michael; Greis, Kenneth D; Devarajan, Prasad 2017. A Novel Biomarker Panel to Identify Steroid Resistance in Childhood Idiopathic Nephrotic Syndrome. Biomarker insights, 12 , 1177271917695832Dwivedi, Pankaj; Greis, Kenneth D 2017. Granulocyte colony-stimulating factor receptor signaling in severe congenital neutropenia, chronic neutrophilic leukemia, and related malignancies. Experimental hematology, 46 , 9-20Fang, Jing; Bolanos, Lyndsey C; Choi, Kwangmin; Liu, Xiaona; Christie, Susanne; Akunuru, Shailaja; Kumar, Rupali; Wang, Dehua; Chen, Xiaoting; Greis, Kenneth D; Stoilov, Peter; Filippi, Marie-Dominique; Maciejewski, Jaroslaw P; Garcia-Manero, Guillermo; Weirauch, Matthew T; Salamonis, Nathan; Geiger, Hartmut; Zheng, Yi; Starczynowski, Daniel T 2017. Corrigendum: Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia. Nature immunology, 18 4, 474Fang, Jing; Bolanos, Lyndsey C; Choi, Kwangmin; Liu, Xiaona; Christie, Susanne; Akunuru, Shailaja; Kumar, Rupali; Wang, Dehua; Chen, Xiaoting; Greis, Kenneth D; Stoilov, Peter; Filippi, Marie-Dominique; Maciejewski, Jaroslaw P; Garcia-Manero, Guillermo; Weirauch, Matthew T; Salomonis, Nathan; Geiger, Hartmut; Zheng, Yi; Starczynowski, Daniel T 2017. Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia. Nature immunology, 18 2, 236-245Blanco, Víctor M; Chu, Zhengtao; LaSance, Kathleen; Gray, Brian D; Yan Pak, Koon; Rider, Therese; Greis, Kenneth D; Qi, Xiaoyang 2016. Optical and nuclear imaging of glioblastoma with phosphatidylserine-targeted nanovesicles. Oncotarget, , Heaven, Michael R; Funk, Adam J; Cobbs, Archie L; Haffey, Wendy D; Norris, Jeremy L; McCullumsmith, Robert E; Greis, Kenneth D 2016. Systematic evaluation of data-independent acquisition for sensitive and reproducible proteomics-a prototype design for a single injection assay. Journal of mass spectrometry : JMS, 51 1, 1-11Kirley, Terence L; Greis, Kenneth D; Norman, Andrew B 2016. Selective disulfide reduction for labeling and enhancement of Fab antibody fragments. Biochemical and biophysical research communications, 480 4, 752-757Kirley, Terence L; Greis, Kenneth D; Norman, Andrew B 2016. Structural characterization of expressed monoclonal antibodies by single sample mass spectral analysis after IdeS proteolysis. Biochemical and biophysical research communications, 477 3, 363-8Sedlacek, Christopher J; Nielsen, Susanne; Greis, Kenneth D; Haffey, Wendy D; Revsbech, Niels Peter; Ticak, Tomislav; Laanbroek, Hendrikus J; Bollmann, Annette 2016. Effects of Bacterial Community Members on the Proteome of the Ammonia-Oxidizing Bacterium Nitrosomonas sp. Strain Is79. Applied and environmental microbiology, 82 15, 4776-88Hasegawa, Kazuteru; Sin, Ho-Su; Maezawa, So; Broering, Tyler J; Kartashov, Andrey V; Alavattam, Kris G; Ichijima, Yosuke; Zhang, Fan; Bacon, W Clark; Greis, Kenneth D; Andreassen, Paul R; Barski, Artem; Namekawa, Satoshi H 2015. SCML2 establishes the male germline epigenome through regulation of histone H2A ubiquitination. Developmental cell, 32 5, 574-88Huang, Yan; Powers, Corey; Madala, Satish K; Greis, Kenneth D; Haffey, Wendy D; Towbin, Jeffrey A; Purevjav, Enkhsaikhan; Javadov, Sabzali; Strauss, Arnold W; Khuchua, Zaza 2015. Cardiac metabolic pathways affected in the mouse model of barth syndrome. PloS one, 10 6, e0128561Huang,Y., Powers,C., Madala,S. K., Greis,K. D., Haffey,W. D., Towbin,J. A., Purevjav,E., Javadov,S., Strauss,A. W., Khuchua,Z. 2015. Cardiac metabolic pathways affected in the mouse model of barth syndrome PloS one, 10 6, e0128561Lu, Xiaoming; Zoller, Erin E; Weirauch, Matthew T; Wu, Zhiguo; Namjou, Bahram; Williams, Adrienne H; Ziegler, Julie T; Comeau, Mary E; Marion, Miranda C; Glenn, Stuart B; Adler, Adam; Shen, Nan; Nath, Swapan K; Stevens, Anne M; Freedman, Barry I; Tsao, Betty P; Jacob, Chaim O; Kamen, Diane L; Brown, Elizabeth E; Gilkeson, Gary S; Alarcón, Graciela S; Reveille, John D; Anaya, Juan-Manuel; James, Judith A; Sivils, Kathy L; Criswell, Lindsey A; Vilá, Luis M; Alarcón-Riquelme, Marta E; Petri, Michelle; Scofield, R Hal; Kimberly, Robert P; Ramsey-Goldman, Rosalind; Joo, Young Bin; Choi, Jeongim; Bae, Sang-Cheol; Boackle, Susan A; Graham, Deborah Cunninghame; Vyse, Timothy J; Guthridge, Joel M; Gaffney, Patrick M; Langefeld, Carl D; Kelly, Jennifer A; Greis, Kenneth D; Kaufman, Kenneth M; Harley, John B; Kottyan, Leah C 2015. Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression. American journal of human genetics, 96 5, 731-9Marsh, J M; Davis, M G; Flagler, M J; Sun, Y; Chaudhary, T; Mamak, M; McComb, D W; Williams, R E A; Greis, K D; Rubio, L; Coderch, L 2015. Advanced hair damage model from ultra-violet radiation in the presence of copper. International journal of cosmetic science, 37 5, 532-41Marsh,J. M., Davis,M. G., Flagler,M. J., Sun,Y., Chaudhary,T., Mamak,M., McComb,D. W., Williams,R. E., Greis,K. D., Rubio,L., Coderch,L. 2015. Advanced hair damage model from ultra-violet radiation in the presence of copper International Journal of Cosmetic Science, 37 5, 532-41Thowfeik, Fathima Shazna; AbdulSalam, Safnas F; Wunderlich, Mark; Wyder, Michael; Greis, Kenneth D; Kadekaro, Ana L; Mulloy, James C; Merino, Edward J 2015. A ROS-Activatable Agent Elicits Homologous Recombination DNA Repair and Synergizes with Pathway Compounds. Chembiochem : a European journal of chemical biology, 16 17, 2513-21Wijeratne, Aruna B; Wijesundera, Dharshana N; Paulose, Maggie; Ahiabu, Ivy Belinda; Chu, Wei-Kan; Varghese, Oomman K; Greis, Kenneth D 2015. Phosphopeptide separation using radially aligned titania nanotubes on titanium wire. ACS applied materials & interfaces, 7 21, 11155-64Wijeratne,A. B., Wijesundera,D. N., Paulose,M., Ahiabu,I. B., Chu,W. K., Varghese,O. K., Greis,K. D. 2015. Phosphopeptide separation using radially aligned titania nanotubes on titanium wire ACS applied materials & interfaces, 7 21, 11155Liou B.;Haffey W.;Greis K.;Grabowski G. 2014. The LIMP-2/SCARB2 binding motif on acid Beta-Glucosidase: Basic and applied implications for Gaucher disease and associated neurodegenerative diseases Journal of Biological Chemistry, 289 43, 30063-74Liou, Benjamin; Haffey, Wendy D; Greis, Kenneth D; Grabowski, Gregory A 2014. The LIMP-2/SCARB2 binding motif on acid ?-glucosidase: basic and applied implications for Gaucher disease and associated neurodegenerative diseases. The Journal of biological chemistry, 289 43, 30063-74Marsh, JM; Iveson, R; Flagler, MJ; Davis, MG; Newland, AB; Greis, KD; Sun, Y; Chaudhary, T; Aistrup, ER 2014. Role of copper in photochemical damage to hair International journal of cosmetic science, 36 1, 32-8Green, Julianne V; Orsborn, Kris I; Zhang, Minlu; Tan, Queenie K G; Greis, Kenneth D; Porollo, Alexey; Andes, David R; Long Lu, Jason; Hostetter, Margaret K 2013. Heparin-binding motifs and biofilm formation by Candida albicans. The Journal of infectious diseases, 208 10, 1695-704Wijeratne, Aruna B; Manning, Janet R; Schultz, Jo El J; Greis, Kenneth D 2013. Quantitative phosphoproteomics using acetone-based Peptide labeling: method evaluation and application to a cardiac ischemia/reperfusion model. Journal of proteome research, 12 10, 4268-79Gauthamadasa, Kekulawalage; Vaitinadin, Nataraja Sarma; Dressman, James L; Macha, Stephen; Homan, Reyn; Greis, Kenneth D; Silva, R A Gangani D 2012. Apolipoprotein A-II-mediated conformational changes of apolipoprotein A-I in discoidal high density lipoproteins. The Journal of biological chemistry, 287 10, 7615-25Govindan, Suresh; McElligott, Andrew; Muthusamy, Saminathan; Nair, Nandini; Barefield, David; Martin, Jody L; Gongora, Enrique; Greis, Kenneth D; Luther, Pradeep K; Winegrad, Saul; Henderson, Kyle K; Sadayappan, Sakthivel 2012. Cardiac myosin binding protein-C is a potential diagnostic biomarker for myocardial infarction. Journal of molecular and cellular cardiology, 52 1, 154-64Kattamuri, Chandramohan; Luedeke, David M; Nolan, Kristof; Rankin, Scott A; Greis, Kenneth D; Zorn, Aaron M; Thompson, Thomas B 2012. Members of the DAN family are BMP antagonists that form highly stable noncovalent dimers. Journal of molecular biology, 424 5, 313-27Djung, Jane F; Mears, Richard J; Montalbetti, Christian A G N; Coulter, Thomas S; Golebiowski, Adam; Carr, Andrew N; Barker, Oliver; Greis, Kenneth D; Zhou, Songtao; Dolan, Elizabeth; Davis, Gregory F 2011. The synthesis and evaluation of indolylureas as PKC? inhibitors. Bioorganic & medicinal chemistry, 19 8, 2742-50Linares J.;Amanchy R.;Greis K.;Diaz-Meco M.;Moscat J. 2011. Author's correction: Phosphorylation of p62 by cdk1 controls the timely transit of cells through mit Molecular and Cellular Biology, 31 10, 2171Linares, Juan F; Amanchy, Ramars; Greis, Kenneth; Diaz-Meco, Maria T; Moscat, Jorge 2011. Phosphorylation of p62 by cdk1 controls the timely transit of cells through mitosis and tumor cell proliferation. Molecular and cellular biology, 31 1, 105-17Myer, David L; Robbins, Susan B; Yin, Moying; Boivin, Gregory P; Liu, Yang; Greis, Kenneth D; Bahassi, El Mustapha; Stambrook, Peter J 2011. Absence of polo-like kinase 3 in mice stabilizes Cdc25A after DNA damage but is not sufficient to produce tumors. Mutation research, 714 1-2, 1-10Piyaphanee, Nuntawan; Ma, Qing; Kremen, Oran; Czech, Kimberly; Greis, Kenneth; Mitsnefes, Mark; Devarajan, Prasad; Bennett, Michael R 2011. Discovery and initial validation of ? 1-B glycoprotein fragmentation as a differential urinary biomarker in pediatric steroid-resistant nephrotic syndrome. Proteomics. Clinical applications, 5 5-6, 334-42Ridsdale, Ross; Na, Cheng-Lun; Xu, Yan; Greis, Kenneth D; Weaver, Timothy 2011. Comparative proteomic analysis of lung lamellar bodies and lysosome-related organelles. PloS one, 6 1, e16482Rathore, Rakesh; Pribil, Patrick; Corr, Jay J; Seibel, William L; Evdokimov, Artem; Greis, Kenneth D 2010. Multiplex Enzyme Assays and Inhibitor Screening by Mass Spectrometry. Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening, , Aslan, Joseph E; You, Huihong; Williamson, Danielle M; Endig, Jessica; Youker, Robert T; Thomas, Laurel; Shu, Hongjun; Du, Yuhong; Milewski, Robert L; Brush, Matthew H; Possemato, Anthony; Sprott, Kam; Fu, Haian; Greis, Kenneth D; Runckel, Douglas N; Vogel, Arndt; Thomas, Gary 2009. Akt and 14-3-3 control a PACS-2 homeostatic switch that integrates membrane traffic with TRAIL-induced apoptosis. Molecular cell, 34 4, 497-509Eismann, Thorsten; Huber, Nadine; Shin, Thomas; Kuboki, Satoshi; Galloway, Elizabeth; Wyder, Michael; Edwards, Michael J; Greis, Kenneth D; Shertzer, Howard G; Fisher, Aron B; Lentsch, Alex B 2009. Peroxiredoxin-6 protects against mitochondrial dysfunction and liver injury during ischemia-reperfusion in mice. American journal of physiology. Gastrointestinal and liver physiology, 296 2, G266-74Haffey, Wendy D; Mikhaylova, Olga; Meller, Jarek; Yi, Ying; Greis, Kenneth D; Czyzyk-Krzeska, Maria F 2009. iTRAQ proteomic identification of pVHL-dependent and -independent targets of Egln1 prolyl hydroxylase knockdown in renal carcinoma cells. Advances in enzyme regulation, 49 1, 121-32Rathore, Rakesh; Corr, Jay J; Lebre, Daniel T; Seibel, William L; Greis, Kenneth D 2009. Extending matrix-assisted laser desorption/ionization triple quadrupole mass spectrometry enzyme screening assays to targets with small molecule substrates. Rapid communications in mass spectrometry : RCM, 23 20, 3293-300Stella, Caroline L; Bennett, Michael R; Devarajan, Prasad; Greis, Kenneth; Wyder, Michael; Macha, Stephen; Rao, Marepalli; Jodicke, Cristiano; Moussa, Hind; How, Helen Y; Myatt, Leslie; Webster, Rose; Sibai, Baha M 2009. Preterm labor biomarker discovery in serum using 3 proteomic profiling methodologies. American journal of obstetrics and gynecology, 201 4, 387.e1-13Suzuki, Michiko; Wiers, Kristina; Brooks, Elizabeth B; Greis, Kenneth D; Haines, Kathleen; Klein-Gitelman, Marisa S; Olson, Judyann; Onel, Karen; O 2009. Initial validation of a novel protein biomarker panel for active pediatric lupus nephritis. Pediatric research, 65 5, 530-6Mikhaylova, Olga; Ignacak, Monika L; Barankiewicz, Teresa J; Harbaugh, Svetlana V; Yi, Ying; Maxwell, Patrick H; Schneider, Martin; Van Geyte, Katie; Carmeliet, Peter; Revelo, Monica P; Wyder, Michael; Greis, Kenneth D; Meller, Jarek; Czyzyk-Krzeska, Maria F 2008. The von Hippel-Lindau tumor suppressor protein and Egl-9-Type proline hydroxylases regulate the large subunit of RNA polymerase II in response to oxidative stress. Molecular and cellular biology, 28 8, 2701-17Rathore, Rakesh; Corr, Jay; Scott, George; Vollmerhaus, Pauline; Greis, Kenneth D 2008. Development of an inhibitor screening platform via mass spectrometry. Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening, 13 10, 1007-13Greis, Kenneth D 2007. Mass spectrometry for enzyme assays and inhibitor screening: an emerging application in pharmaceutical research. Mass spectrometry reviews, 26 3, 324-39Greis, Kenneth D; Zhou, Songtao; Burt, Thomas M; Carr, Andrew N; Dolan, Elizabeth; Easwaran, Vijayasurian; Evdokimov, Artem; Kawamoto, Richard; Roesgen, Jeff; Davis, Gregory F 2006. MALDI-TOF MS as a label-free approach to rapid inhibitor screening. Journal of the American Society for Mass Spectrometry, 17 6, 815-22Greis, Kenneth D; Zhou, Songtao; Siehnel, Richard; Klanke, Chuck; Curnow, Alan; Howard, Jeremy; Layh-Schmitt, Gerlinde 2005. Development and validation of a whole-cell inhibition assay for bacterial methionine aminopeptidase by surface-enhanced laser desorption ionization-time of flight mass spectrometry. Antimicrobial agents and chemotherapy, 49 8, 3428-34Jarrold, Bradley; DeMuth, Jeffrey; Greis, Kenneth; Burt, Thomas; Wang, Feng 2005. An effective skeletal muscle prefractionation method to remove abundant structural proteins for optimized two-dimensional gel electrophoresis Electrophoresis, 26 11, 2269-78Peters, Kevin G; Davis, Mike G; Howard, Brian W; Pokross, Matthew; Rastogi, Vinit; Diven, Conrad; Greis, Kenneth D; Eby-Wilkens, Elaine; Maier, Matthew; Evdokimov, Artem; Soper, Shari; Genbauffe, Frank 2003. Mechanism of insulin sensitization by BMOV (bis maltolato oxo vanadium); unliganded vanadium (VO4) as the active component. Journal of inorganic biochemistry, 96 2-3, 321-30Thompson, Larry J; Wang, Feng; Proia, Alan D; Peters, Kevin G; Jarrold, Brad; Greis, Kenneth D 2003. Proteome analysis of the rat cornea during angiogenesis. Proteomics, 3 11, 2258-66Delinsky, David C; Greis, Kenneth D 2002. Capillary chromatography-coupled mass spectrometry with column switching for rapid identification of proteins from 2-dimensional electrophoresis gels. Journal of proteome research, 1 3, 279-84Isfort, Robert J; Wang, Feng; Greis, Kenneth D; Sun, Yiping; Keough, Thomas W; Bodine, Sue C; Anderson, N Leigh 2002. Proteomic analysis of rat soleus and tibialis anterior muscle following immobilization. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 769 2, 323-32Isfort, Robert J; Wang, Feng; Greis, Kenneth D; Sun, Yiping; Keough, Thomas W; Farrar, Roger P; Bodine, Sue C; Anderson, N Leigh 2002. Proteomic analysis of rat soleus muscle undergoing hindlimb suspension-induced atrophy and reweighting hypertrophy. Proteomics, 2 5, 543-50Egnaczyk, G F; Greis, K D; Stimson, E R; Maggio, J E 2001. Photoaffinity cross-linking of Alzheimer's disease amyloid fibrils reveals interstrand contact regions between assembled beta-amyloid peptide subunits. Biochemistry, 40 39, 11706-14Hoke S.;Morand K.;Greis K.;Baker T.;Harbol K.;Dobson R. 2001. Transformations in pharmaceutical research and development, driven by innovations in multidimensiona International Journal of Mass Spectrometry, 212 1-3, 135-196Isfort, R J; Hinkle, R T; Jones, M B; Wang, F; Greis, K D; Sun, Y; Keough, T W; Anderson, N L; Sheldon, R J 2000. Proteomic analysis of the atrophying rat soleus muscle following denervation. Electrophoresis, 21 11, 2228-34Sanchez, V; Greis, K D; Sztul, E; Britt, W J 2000. Accumulation of virion tegument and envelope proteins in a stable cytoplasmic compartment during human cytomegalovirus replication: characterization of a potential site of virus assembly. Journal of virology, 74 2, 975-86Smaill, ; Rewcastle, ; Loo, ; Greis, ; Chan, ; Reyner, ; Lipka, ; Showalter, ; Vincent, ; Elliott, ; Denny, 2000. Tyrosine kinase inhibitors. 17. Irreversible inhibitors of the epidermal growth factor receptor: 4-(Phenylamino)quinazoline- and 4-(Phenylamino)pyrido Journal of medicinal chemistry, 43 16, 3199Smaill, J B; Rewcastle, G W; Loo, J A; Greis, K D; Chan, O H; Reyner, E L; Lipka, E; Showalter, H D; Vincent, P W; Elliott, W L; Denny, W A 2000. Tyrosine kinase inhibitors. 17. Irreversible inhibitors of the epidermal growth factor receptor: 4-(phenylamino)quinazoline- and 4-(phenylamino)pyrido[3,2-d]pyrimidine-6-acrylamides bearing additional solubilizing functions. Journal of medicinal chemistry, 43 7, 1380-97VanBogelen, R A; Greis, K D; Blumenthal, R M; Tani, T H; Matthews, R G 1999. Mapping regulatory networks in microbial cells. Trends in microbiology, 7 8, 320-8Fry, D W; Bridges, A J; Denny, W A; Doherty, A; Greis, K D; Hicks, J L; Hook, K E; Keller, P R; Leopold, W R; Loo, J A; McNamara, D J; Nelson, J M; Sherwood, V; Smaill, J B; Trumpp-Kallmeyer, S; Dobrusin, E M 1998. Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor. Proceedings of the National Academy of Sciences of the United States of America, 95 20, 12022-7Greis, K D; Hart, G W 1998. Analytical methods for the study of O-GlcNAc glycoproteins and glycopeptides. Methods in molecular biology (Clifton, N.J.), 76 , 19-33Stevenson, T I; Loo, J A; Greis, K D 1998. Coupling capillary high-performance liquid chromatography to matrix-assisted laser desorption/ionization mass spectrometry and N-terminal sequencing of peptides via automated microblotting onto membrane substrates. Analytical biochemistry, 262 2, 99-109Greis K.D.;Hart G.W. 1997. Chapter 2 Nuclear and Cytoplasmic Glycoproteins New Comprehensive Biochemistry, 29 PART B, 33-54Greis, K D; Hayes, B K; Comer, F I; Kirk, M; Barnes, S; Lowary, T L; Hart, G W 1996. Selective detection and site-analysis of O-GlcNAc-modified glycopeptides by beta-elimination and tandem electrospray mass spectrometry. Analytical biochemistry, 234 1, 38-49Greis, K D; Zhu, S; Matalon, S 1996. Identification of nitration sites on surfactant protein A by tandem electrospray mass spectrometry. Archives of biochemistry and biophysics, 335 2, 396-402Hart G.W.;Greis K.D.;Dong L.Y.D.;Blomberg M.A.;Chou T.Y.;Jiang M.S.;Roquemore E.P.;Snow D.M.;Kreppel L.K.;Cole R.C.;Hayes B.K. 1995. Ubiquitous and temporal glycosylation of nuclear and cytoplasmic proteins Pure and Applied Chemistry, 67 10, 1637-1645Hart, G W; Greis, K D; Dong, L Y; Blomberg, M A; Chou, T Y; Jiang, M S; Roquemore, E P; Snow, D M; Kreppel, L K; Cole, R N 1995. O-linked N-acetylglucosamine: the "yin-yang" of Ser/Thr phosphorylation? Nuclear and cytoplasmic glycosylation. Advances in experimental medicine and biology, 376 , 115-23Hayes, B K; Greis, K D; Hart, G W 1995. Specific isolation of O-linked N-acetylglucosamine glycopeptides from complex mixtures. Analytical biochemistry, 228 1, 115-22Greis, K D; Gibson, W; Hart, G W 1994. Site-specific glycosylation of the human cytomegalovirus tegument basic phosphoprotein (UL32) at serine 921 and serine 952. Journal of virology, 68 12, 8339-49Greis, K D; Turco, S J; Thomas, J R; McConville, M J; Homans, S W; Ferguson, M A 1992. Purification and characterization of an extracellular phosphoglycan from Leishmania donovani. The Journal of biological chemistry, 267 9, 5876-81Thomas, J R; McConville, M J; Thomas-Oates, J E; Homans, S W; Ferguson, M A; Gorin, P A; Greis, K D; Turco, S J 1992. Refined structure of the lipophosphoglycan of Leishmania donovani. The Journal of biological chemistry, 267 10, 6829-33Crawford, I T; Greis, K D; Parks, L; Streips, U N 1987. Facile autoplast generation and transformation in Bacillus thuringiensis subsp. kurstaki. Journal of bacteriology, 169 12, 5423-8 Kirley T.L.; Greis K.D.; Norman A.B. 12-01-2018. Domain unfolding of monoclonal antibody fragments revealed by non-reducing SDS-PAGE Biochemistry and Biophysics Reports, 16 , 138-144 Jarrold B.; DeMuth J.; Greis K.; Burt T.; Wang F. 12-01-2005. An effective skeletal muscle prefractionation method to remove abundant structural proteins for opti AIChE Annual Meeting, Conference Proceedings, , 12387-12396 Delinsky D.; Greis K. 12-01-2002. Rapid capillary LC-ESI-MS/MS via column switching for proteomics applications Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics, , 155-156 Linares J.; Amanchy R.; Greis K.; Diaz-Meco M.; Moscat J. 08-01-2017. Correction: "Phosphorylation of p62 by cdk1 controls the timely transit of cells through mitosis and Molecular and Cellular Biology, 37 15, Bennett M.R.; Pleasant L.T.; Haffner C.; Ma Q.; Haffey W.D.; Ying J.; Wagner M.; Greis K.D.; Devarajan P. 03-08-2017. A novel biomarker panel to identify steroid resistance in childhood idiopathic nephrotic syndrome Biomarker Insights, 12 , Forster C.; Haffey W.; Bennett M.; Greis K.; Devarajan P. 03-01-2019. Identification of Urinary CD44 and Prosaposin as Specific Biomarkers of Urinary Tract Infections in Biomarker Insights, 14 , Yuan L.; Mishra R.; Patel H.; Abdulsalam S.; Greis K.; Kadekaro A.; Merino E.; Garrett J. 01-01-2018. Utilization of reactive oxygen species targeted therapy to prolong the efficacy of braf inhibitors i Journal of Cancer, 9 24, 4665-4676