Contact Information Childrens Hospital Bldg R Office 513-636-7603 Email waysg@ucmail.uc.edu Research InterestsI work in infectious disease pediatrics because I love kids and I love taking care of them. Patients are the most vulnerable during infancy and early life development, which means they need advocates for their health. My research interests include infectious diseases, reproductive biology, developmental biology and immunology. I was attracted to my research when I became frustrated with not being able to tell parents why their child became sick and how to prevent their illness in the future... Peer Reviewed Publications Erickson, John J; Archer-Hartmann, Stephanie; Yarawsky, Alexander E; Miller, Jeanette L C; Seveau, Stephanie; Shao, Tzu-Yu; Severance, Ashley L; Miller-Handley, Hilary; Wu, Yuehong; Pham, Giang; Wasik, Brian R; Parrish, Colin R; Hu, Yueh-Chiang; Lau, Joseph T Y; Azadi, Parastoo; Herr, Andrew B; Way, Sing Sing 2022. Pregnancy enables antibody protection against intracellular infection. Nature, 606 7915, 769-775McDaniel, Margaret M; Chawla, Amanpreet Singh; Jain, Aakanksha; Meibers, Hannah E; Saha, Irene; Gao, Yajing; Jain, Viral; Roskin, Krishna; Way, Sing Sing; Pasare, Chandrashekhar 2022. Effector memory CD4+ T cells induce damaging innate inflammation and autoimmune pathology by engaging CD40 and TNFR on myeloid cells. Science immunology, 7 67, eabk0182Severance, Ashley L; Kinder, Jeremy M; Xin, Lijun; Burg, Ashley R; Shao, Tzu-Yu; Pham, Giang; Tilburgs, Tamara; Goodman, Wendy A; Mesiano, Sam; Way, Sing Sing 2022. Maternal-fetal conflict averted by progesterone- induced FOXP3+ regulatory T cells. iScience, 25 6, 104400Shao, Tzu-Yu; Kakade, Pallavi; Witchley, Jessica N; Frazer, Corey; Murray, Kathryn L; Ene, Iuliana V; Haslam, David B; Hagan, Thomas; Noble, Suzanne M; Bennett, Richard J; Way, Sing Sing 2022. Candida albicans oscillating UME6 expression during intestinal colonization primes systemic Th17 protective immunity. Cell reports, 39 7, 110837Alarcon, Pablo C; Damen, Michelle S M A; Madan, Rajat; Deepe, George S; Spearman, Paul; Way, Sing Sing; Divanovic, Senad 2021. Adipocyte inflammation and pathogenesis of viral pneumonias: an overlooked contribution. Mucosal immunology, 14 6, 1224-1234Bianchi, Diana W; Khosrotehrani, Kiarash; Way, Sing Sing; MacKenzie, Tippi C; Bajema, Ingeborg; O'Donoghue, Keelin 2021. Forever Connected: The Lifelong Biological Consequences of Fetomaternal and Maternofetal Microchimerism. Clinical chemistry, 67 2, 351-362Cappelletti, Monica; Presicce, Pietro; Feiyang, Ma; Senthamaraikannan, Paranthaman; Miller, Lisa A; Pellegrini, Matteo; Sim, Myung S; Jobe, Alan H; Divanovic, Senad; Way, Sing Sing; Chougnet, Claire A; Kallapur, Suhas G 2021. The induction of preterm labor in rhesus macaques is determined by the strength of immune response to intrauterine infection. PLoS biology, 19 9, e3001385Chen, Didi; Burford, Wesley B; Pham, Giang; Zhang, Lishu; Alto, Laura T; Ertelt, James M; Winter, Maria G; Winter, Sebastian E; Way, Sing Sing; Alto, Neal M 2021. Systematic reconstruction of an effector-gene network reveals determinants of Salmonella cellular and tissue tropism. Cell host & microbe, 29 10, 1531-1544.e9Gregory, Emily J; Liu, James; Miller-Handley, Hilary; Kinder, Jeremy M; Way, Sing Sing 2021. Epidemiology of Pregnancy Complications Through the Lens of Immunological Memory. Frontiers in immunology, 12 , 693189Miller-Handley, Hilary; Erickson, John J; Gregory, Emily J; Prasanphanich, Nina Salinger; Shao, Tzu-Yu; Way, Sing Sing 2021. Tacrolimus exposure windows responsible for Listeria monocytogenes infection susceptibility. Transplant infectious disease : an official journal of the Transplantation Society, 23 4, e13655Prasanphanich, Nina Salinger; Gregory, Emily J; Erickson, John J; Miller-Handley, Hilary; Kinder, Jeremy M; Way, Sing Sing 2021. Preconceptual Priming Overrides Susceptibility to Escherichia coli Systemic Infection during Pregnancy. mBio, 12 1, Zhang, Jizhou; Wu, Qingqing; Johnson, Courtney B; Pham, Giang; Kinder, Jeremy M; Olsson, Andre; Slaughter, Anastasiya; May, Margot; Weinhaus, Benjamin; D'Alessandro, Angelo; Engel, James Douglas; Jiang, Jean X; Kofron, J Matthew; Huang, L Frank; Prasath, V B Surya; Way, Sing Sing; Salomonis, Nathan; Grimes, H Leighton; Lucas, Daniel 2021. In situ mapping identifies distinct vascular niches for myelopoiesis. Nature, 590 7846, 457-462Almanan, Maha; Raynor, Jana; Ogunsulire, Ireti; Malyshkina, Anna; Mukherjee, Shibabrata; Hummel, Sarah A; Ingram, Jennifer T; Saini, Ankur; Xie, Markus M; Alenghat, Theresa; Way, Sing Sing; Deepe, George S; Divanovic, Senad; Singh, Harinder; Miraldi, Emily; Zajac, Allan J; Dent, Alexander L; Hölscher, Christoph; Chougnet, Claire; Hildeman, David A 2020. IL-10-producing Tfh cells accumulate with age and link inflammation with age-related immune suppression. Science advances, 6 31, eabb0806Burg, Ashley R; Erickson, John J; Turner, Lucien H; Pham, Giang; Kinder, Jeremy M; Way, Sing Sing 2020. Persistent Zika Virus Clinical Susceptibility despite Reduced Viral Burden in Mice with Expanded Virus-Specific CD8+ T Cells Primed by Recombinant Listeria monocytogenes. Journal of immunology (Baltimore, Md. : 1950), 205 2, 447-453Chen, Yee-Shiuan; Chen, Iuan-Bor; Pham, Giang; Shao, Tzu-Yu; Bangar, Hansraj; Way, Sing Sing; Haslam, David B 2020. IL-17-producing ?? T cells protect against Clostridium difficile infection. The Journal of clinical investigation, 130 5, 2377-2390Kinder, Jeremy M; Turner, Lucien H; Stelzer, Ina A; Miller-Handley, Hilary; Burg, Ashley; Shao, Tzu-Yu; Pham, Giang; Way, Sing Sing 2020. CD8+ T Cell Functional Exhaustion Overrides Pregnancy-Induced Fetal Antigen Alloimmunization. Cell reports, 31 12, 107784Kollmann, Tobias R; Marchant, Arnaud; Way, Sing Sing 2020. Vaccination strategies to enhance immunity in neonates. Science (New York, N.Y.), 368 6491, 612-615Muench, David E; Olsson, Andre; Ferchen, Kyle; Pham, Giang; Serafin, Rachel A; Chutipongtanate, Somchai; Dwivedi, Pankaj; Song, Baobao; Hay, Stuart; Chetal, Kashish; Trump-Durbin, Lisa R; Mookerjee-Basu, Jayati; Zhang, Kejian; Yu, Jennifer C; Lutzko, Carolyn; Myers, Kasiani C; Nazor, Kristopher L; Greis, Kenneth D; Kappes, Dietmar J; Way, Sing Sing; Salomonis, Nathan; Grimes, H Leighton 2020. Mouse models of neutropenia reveal progenitor-stage-specific defects. Nature, 582 7810, 109-114Yang, Li; Shivakumar, Pranavkumar; Kinder, Jeremy; Way, Sing Sing; Donnelly, Bryan; Mourya, Reena; Luo, Zhenhua; Bezerra, Jorge A 2020. Regulation of bile duct epithelial injury by hepatic CD71+ erythroid cells. JCI insight, 5 11, Aggor, Felix E Y; Way, Sing Sing; Gaffen, Sarah L 2019. Fungus Among Us: The Frenemies Within. Trends in immunology, 40 6, 469-471Deshmukh, Hitesh; Way, Sing Sing 2019. Immunological Basis for Recurrent Fetal Loss and Pregnancy Complications. Annual review of pathology, 14 , 185-210Kotov, Dmitri I; Mitchell, Jason S; Pengo, Thomas; Ruedl, Christiane; Way, Sing Sing; Langlois, Ryan A; Fife, Brian T; Jenkins, Marc K 2019. TCR Affinity Biases Th Cell Differentiation by Regulating CD25, Eef1e1, and Gbp2. Journal of immunology (Baltimore, Md. : 1950), 202 9, 2535-2545Shao, Tzu-Yu; Ang, W X Gladys; Jiang, Tony T; Huang, Felicia Scaggs; Andersen, Heidi; Kinder, Jeremy M; Pham, Giang; Burg, Ashley R; Ruff, Brandy; Gonzalez, Tammy; Khurana Hershey, Gurjit K; Haslam, David B; Way, Sing Sing 2019. Commensal Candida albicans Positively Calibrates Systemic Th17 Immunological Responses. Cell host & microbe, 25 3, 404-417.e6Deshpande, Neha R; Uhrlaub, Jennifer L; Way, Sing Sing; Nikolich-Žugich, Janko; Kuhns, Michael S 2018. A disconnect between precursor frequency, expansion potential, and site-specific CD4+ T cell responses in aged mice. PloS one, 13 6, e0198354DiToro, Daniel; Winstead, Colleen J; Pham, Duy; Witte, Steven; Andargachew, Rakieb; Singer, Jeffrey R; Wilson, C Garrett; Zindl, Carlene L; Luther, Rita J; Silberger, Daniel J; Weaver, Benjamin T; Kolawole, E Motunrayo; Martinez, Ryan J; Turner, Henrietta; Hatton, Robin D; Moon, James J; Way, Sing Sing; Evavold, Brian D; Weaver, Casey T 2018. Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells. Science (New York, N.Y.), 361 6407, Schlaudecker, Elizabeth P; Ambroggio, Lilliam; McNeal, Monica M; Finkelman, Fred D; Way, Sing Sing 2018. Declining responsiveness to influenza vaccination with progression of human pregnancy. Vaccine, 36 31, 4734-4741Yang, Jason D; Mott, Daniel; Sutiwisesak, Rujapak; Lu, Yu-Jung; Raso, Fiona; Stowell, Britni; Babunovic, Greg Hunter; Lee, Jinhee; Carpenter, Steve M; Way, Sing Sing; Fortune, Sarah M; Behar, Samuel M 2018. Mycobacterium tuberculosis-specific CD4+ and CD8+ T cells differ in their capacity to recognize infected macrophages. PLoS pathogens, 14 5, e1007060Zhou, Jordan Z; Way, Sing Sing; Chen, Kang 2018. Immunology of Uterine and Vaginal Mucosae: (Trends in Immunology 39, 302-314, 2018). Trends in immunology, 39 4, 355Zhou, Jordan Z; Way, Sing Sing; Chen, Kang 2018. Immunology of the Uterine and Vaginal Mucosae. Trends in immunology, 39 4, 302-314Cappelletti, Monica; Presicce, Pietro; Lawson, Matthew J; Chaturvedi, Vandana; Stankiewicz, Traci E; Vanoni, Simone; Harley, Isaac Tw; McAlees, Jaclyn W; Giles, Daniel A; Moreno-Fernandez, Maria E; Rueda, Cesar M; Senthamaraikannan, Paranth; Sun, Xiaofei; Karns, Rebekah; Hoebe, Kasper; Janssen, Edith M; Karp, Christopher L; Hildeman, David A; Hogan, Simon P; Kallapur, Suhas G; Chougnet, Claire A; Way, Sing Sing; Divanovic, Senad 2017. Type I interferons regulate susceptibility to inflammation-induced preterm birth. JCI insight, 2 5, e91288Jiang, Tony T; Shao, Tzu-Yu; Ang, W X Gladys; Kinder, Jeremy M; Turner, Lucien H; Pham, Giang; Whitt, Jordan; Alenghat, Theresa; Way, Sing Sing 2017. Commensal Fungi Recapitulate the Protective Benefits of Intestinal Bacteria. Cell host & microbe, 22 6, 809-816.e4Kinder, Jeremy M; Stelzer, Ina A; Arck, Petra C; Way, Sing Sing 2017. Reply: Breastfeeding-related maternal microchimerism. Nature reviews. Immunology, 17 11, 730-1Kinder, Jeremy M; Stelzer, Ina A; Arck, Petra C; Way, Sing Sing 2017. Immunological implications of pregnancy-induced microchimerism. Nature reviews. Immunology, 17 8, 483-494Lange, Shannon M; McKell, Melanie C; Schmidt, Stephanie M; Hossfeld, Austin P; Chaturvedi, Vandana; Kinder, Jeremy M; McAlees, Jaclyn W; Lewkowich, Ian P; Way, Sing Sing; Turner, Joanne; Qualls, Joseph E 2017. l-Citrulline Metabolism in Mice Augments CD4+ T Cell Proliferation and Cytokine Production In Vitro, and Accumulation in the Mycobacteria-Infected Lung. Frontiers in immunology, 8 , 1561Navabi, Nazanin; Whitt, Jordan; Wu, Shu-En; Woo, Vivienne; Moncivaiz, Jessica; Jordan, Michael B; Vallance, Bruce A; Way, Sing Sing; Alenghat, Theresa 2017. Epithelial Histone Deacetylase 3 Instructs Intestinal Immunity by Coordinating Local Lymphocyte Activation. Cell reports, 19 6, 1165-1175Turner, Lucien H; Kinder, Jeremy M; Wilburn, Adrienne; D'Mello, Rahul J; Braunlin, Makayla R; Jiang, Tony T; Pham, Giang; Way, Sing Sing 2017. Preconceptual Zika virus asymptomatic infection protects against secondary prenatal infection. PLoS pathogens, 13 11, e1006684Carpenter, Stephen M; Nunes-Alves, Cláudio; Booty, Matthew G; Way, Sing Sing; Behar, Samuel M 2016. A Higher Activation Threshold of Memory CD8+ T Cells Has a Fitness Cost That Is Modified by TCR Affinity during Tuberculosis. PLoS pathogens, 12 1, e1005380Jiang, Tony T; Martinov, Tijana; Xin, Lijun; Kinder, Jeremy M; Spanier, Justin A; Fife, Brian T; Way, Sing Sing 2016. Programmed Death-1 Culls Peripheral Accumulation of High-Affinity Autoreactive CD4 T Cells to Protect against Autoimmunity. Cell reports, 17 7, 1783-1794Johnson, Lexus R; Weizman, Orr-El; Rapp, Moritz; Way, Sing Sing; Sun, Joseph C 2016. Epitope-Specific Vaccination Limits Clonal Expansion of Heterologous Naive T Cells during Viral Challenge. Cell reports, 17 3, 636-644Kinder, Jeremy M; Jiang, Tony T; Way, Sing Sing 2016. Offspring's Tolerance of Mother Goes Viral. Immunity, 44 5, 1085-7Rosenblum, Michael D; Way, Sing Sing; Abbas, Abul K 2016. Regulatory T cell memory. Nature reviews. Immunology, 16 2, 90-101Chaturvedi, Vandana; Ertelt, James M; Jiang, Tony T; Kinder, Jeremy M; Xin, Lijun; Owens, Kathryn J; Jones, Helen N; Way, Sing Sing 2015. CXCR3 blockade protects against Listeria monocytogenes infection-induced fetal wastage. The Journal of clinical investigation, 125 4, 1713-25Kinder, Jeremy M; Jiang, Tony T; Ertelt, James M; Xin, Lijun; Strong, Beverly S; Shaaban, Aimen F; Way, Sing Sing 2015. Cross-Generational Reproductive Fitness Enforced by Microchimeric Maternal Cells. Cell, 162 3, 505-15Kinder, Jeremy M; Jiang, Tony T; Ertelt, James M; Xin, Lijun; Strong, Beverly S; Shaaban, Aimen F; Way, Sing Sing 2015. Tolerance to noninherited maternal antigens, reproductive microchimerism and regulatory T cell memory: 60 years after 'Evidence for actively acquired tolerance to Rh antigens'. Chimerism, 6 1-2, 8-20Legoux, Francois P; Lim, Jong-Baeck; Cauley, Andrew W; Dikiy, Stanislav; Ertelt, James; Mariani, Thomas J; Sparwasser, Tim; Way, Sing Sing; Moon, James J 2015. CD4+ T Cell Tolerance to Tissue-Restricted Self Antigens Is Mediated by Antigen-Specific Regulatory T Cells Rather Than Deletion. Immunity, 43 5, 896-908Nanton, Minelva R; Lee, Seung-Joo; Atif, Shaikh M; Nuccio, Sean-Paul; Taylor, Justin J; Bäumler, Andreas J; Way, Sing Sing; McSorley, Stephen J 2015. Direct visualization of endogenous Salmonella-specific B cells reveals a marked delay in clonal expansion and germinal center development. European journal of immunology, 45 2, 428-41PrabhuDas, Mercy; Bonney, Elizabeth; Caron, Kathleen; Dey, Sudhansu; Erlebacher, Adrian; Fazleabas, Asgerally; Fisher, Susan; Golos, Thaddeus; Matzuk, Martin; McCune, Joseph M; Mor, Gil; Schulz, Laura; Soares, Michael; Spencer, Thomas; Strominger, Jack; Way, Sing Sing; Yoshinaga, Koji 2015. Immune mechanisms at the maternal-fetal interface: perspectives and challenges. Nature immunology, 16 4, 328-34Xin, Lijun; Jiang, Tony T; Kinder, Jeremy M; Ertelt, James M; Way, Sing Sing 2015. Infection susceptibility and immune senescence with advancing age replicated in accelerated aging Lmna(Dhe) mice. Aging cell, , Clark, Dayna R; Chaturvedi, Vandana; Kinder, Jeremy M; Jiang, Tony T; Xin, Lijun; Ertelt, James M; Way, Sing Sing 2014. Perinatal Listeria monocytogenes susceptibility despite preconceptual priming and maintenance of pathogen-specific CD8(+) T cells during pregnancy. Cellular & molecular immunology, 11 6, 595-605Drummond, Rebecca A; Wallace, Carol; Reid, Delyth M; Way, Sing Sing; Kaplan, Daniel H; Brown, Gordon D 2014. Cutting edge: Failure of antigen-specific CD4+ T cell recruitment to the kidney during systemic candidiasis. Journal of immunology (Baltimore, Md. : 1950), 193 11, 5381-5Jiang, Tony T; Chaturvedi, Vandana; Ertelt, James M; Kinder, Jeremy M; Clark, Dayna R; Valent, Amy M; Xin, Lijun; Way, Sing Sing 2014. Regulatory T cells: new keys for further unlocking the enigma of fetal tolerance and pregnancy complications. Journal of immunology (Baltimore, Md. : 1950), 192 11, 4949-56Xin, Lijun; Ertelt, James M; Rowe, Jared H; Jiang, Tony T; Kinder, Jeremy M; Chaturvedi, Vandana; Elahi, Shokrollah; Way, Sing Sing 2014. Cutting edge: committed Th1 CD4+ T cell differentiation blocks pregnancy-induced Foxp3 expression with antigen-specific fetal loss. Journal of immunology (Baltimore, Md. : 1950), 192 7, 2970-4Xin, Lijun; Jiang, Tony T; Chaturvedi, Vandana; Kinder, Jeremy M; Ertelt, James M; Rowe, Jared H; Steinbrecher, Kris A; Way, Sing Sing 2014. Commensal microbes drive intestinal inflammation by IL-17-producing CD4+ T cells through ICOSL and OX40L costimulation in the absence of B7-1 and B7-2. Proceedings of the National Academy of Sciences of the United States of America, 111 29, 10672-7Burnaevskiy, Nikolay; Fox, Thomas G; Plymire, Daniel A; Ertelt, James M; Weigele, Bethany A; Selyunin, Andrey S; Way, Sing Sing; Patrie, Steven M; Alto, Neal M 2013. Proteolytic elimination of N-myristoyl modifications by the Shigella virulence factor IpaJ. Nature, 496 7443, 106-9Elahi, Shokrollah; Ertelt, James M; Kinder, Jeremy M; Jiang, Tony T; Zhang, Xuzhe; Xin, Lijun; Chaturvedi, Vandana; Strong, Beverly S; Qualls, Joseph E; Steinbrecher, Kris A; Kalfa, Theodosia A; Shaaban, Aimen F; Way, Sing Sing 2013. Immunosuppressive CD71+ erythroid cells compromise neonatal host defence against infection. Nature, 504 7478, 158-62Ertelt, James M; Buyukbasaran, Esra Z; Jiang, Tony T; Rowe, Jared H; Xin, Lijun; Way, Sing Sing 2013. B7-1/B7-2 blockade overrides the activation of protective CD8 T cells stimulated in the absence of Foxp3+ regulatory T cells. Journal of leukocyte biology, 94 2, 367-76Rowe, Jared H; Ertelt, James M; Xin, Lijun; Way, Sing Sing 2013. Regulatory T cells and the immune pathogenesis of prenatal infection. Reproduction (Cambridge, England), 146 6, R191-203Shafiani, Shahin; Dinh, Crystal; Ertelt, James M; Moguche, Albanus O; Siddiqui, Imran; Smigiel, Kate S; Sharma, Pawan; Campbell, Daniel J; Way, Sing Sing; Urdahl, Kevin B 2013. Pathogen-specific Treg cells expand early during mycobacterium tuberculosis infection but are later eliminated in response to Interleukin-12. Immunity, 38 6, 1261-70Tubo, Noah J; Pagán, Antonio J; Taylor, Justin J; Nelson, Ryan W; Linehan, Jonathan L; Ertelt, James M; Huseby, Eric S; Way, Sing Sing; Jenkins, Marc K 2013. Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection. Cell, 153 4, 785-96Kanistanon, Duangjit; Powell, Daniel A; Hajjar, Adeline M; Pelletier, Mark R; Cohen, Ilana E; Way, Sing Sing; Skerrett, Shawn J; Wang, Xiaoyuan; Raetz, Christian R H; Ernst, Robert K 2012. Role of Francisella lipid A phosphate modification in virulence and long-term protective immune responses. Infection and immunity, 80 3, 943-51Nanton, Minelva R; Way, Sing Sing; Shlomchik, Mark J; McSorley, Stephen J 2012. Cutting edge: B cells are essential for protective immunity against Salmonella independent of antibody secretion. Journal of immunology (Baltimore, Md. : 1950), 189 12, 5503-7Rowe, Jared H; Ertelt, James M; Way, Sing Sing 2012. Innate IFN-? is essential for programmed death ligand-1-mediated T cell stimulation following Listeria monocytogenes infection. Journal of immunology (Baltimore, Md. : 1950), 189 2, 876-84Rowe, Jared H; Ertelt, James M; Way, Sing Sing 2012. Foxp3(+) regulatory T cells, immune stimulation and host defence against infection. Immunology, 136 1, 1-10Rowe, Jared H; Ertelt, James M; Xin, Lijun; Way, Sing Sing 2012. Pregnancy imprints regulatory memory that sustains anergy to fetal antigen. Nature, 490 7418, 102-6Rowe, Jared H; Ertelt, James M; Xin, Lijun; Way, Sing Sing 2012. Listeria monocytogenes cytoplasmic entry induces fetal wastage by disrupting maternal Foxp3+ regulatory T cell-sustained fetal tolerance. PLoS pathogens, 8 8, e1002873Ertelt, James M; Johanns, Tanner M; Mysz, Margaret A; Nanton, Minelva R; Rowe, Jared H; Aguilera, Marijo N; Way, Sing Sing 2011. Selective culling of high avidity antigen-specific CD4+ T cells after virulent Salmonella infection. Immunology, 134 4, 487-97Ertelt, James M; Rowe, Jared H; Mysz, Margaret A; Singh, Charanjeet; Roychowdhury, Monika; Aguilera, Marijo N; Way, Sing Sing 2011. Foxp3+ regulatory T cells impede the priming of protective CD8+ T cells. Journal of immunology (Baltimore, Md. : 1950), 187 5, 2569-77Han, Jin-Young; Hanson, David C; Way, Sing Sing 2011. Herpes zoster and meningitis due to reactivation of varicella vaccine virus in an immunocompetent child. The Pediatric infectious disease journal, 30 3, 266-8Johanns, Tanner M; Law, Calvin Y; Kalekar, Lokeshchandra A; O'Donnell, Hope; Ertelt, James M; Rowe, Jared H; Way, Sing Sing 2011. Early eradication of persistent Salmonella infection primes antibody-mediated protective immunity to recurrent infection. Microbes and infection / Institut Pasteur, 13 4, 322-30Rowe, Jared H; Ertelt, James M; Aguilera, Marijo N; Farrar, Michael A; Way, Sing Sing 2011. Foxp3(+) regulatory T cell expansion required for sustaining pregnancy compromises host defense against prenatal bacterial pathogens. Cell host & microbe, 10 1, 54-64Rudd, Brian D; Venturi, Vanessa; Li, Gang; Samadder, Partha; Ertelt, James M; Way, Sing Sing; Davenport, Miles P; Nikolich-Žugich, Janko 2011. Nonrandom attrition of the naive CD8+ T-cell pool with aging governed by T-cell receptor:pMHC interactions. Proceedings of the National Academy of Sciences of the United States of America, 108 33, 13694-9Curtis, Meredith M; Rowell, Emily; Shafiani, Shahin; Negash, Amina; Urdahl, Kevin B; Wilson, Christopher B; Way, Sing Sing 2010. Fidelity of pathogen-specific CD4+ T cells to the Th1 lineage is controlled by exogenous cytokines, interferon-gamma expression, and pathogen lifestyle. Cell host & microbe, 8 2, 163-73Ertelt, James M; Johanns, Tanner M; Rowe, Jared H; Way, Sing Sing 2010. Interleukin (IL)-21-independent pathogen-specific CD8+ T-cell expansion, and IL-21-dependent suppression of CD4+ T-cell IL-17 production. Immunology, 131 2, 183-91Johanns, Tanner M; Ertelt, James M; Lai, Joseph C; Rowe, Jared H; Avant, Ross A; Way, Sing Sing 2010. Naturally occurring altered peptide ligands control Salmonella-specific CD4+ T cell proliferation, IFN-gamma production, and protective potency. Journal of immunology (Baltimore, Md. : 1950), 184 2, 869-76Johanns, Tanner M; Ertelt, James M; Rowe, Jared H; Way, Sing Sing 2010. Regulatory T cell suppressive potency dictates the balance between bacterial proliferation and clearance during persistent Salmonella infection. PLoS pathogens, 6 8, e1001043Rudd, Brian D; Venturi, Vanessa; Smithey, Megan J; Way, Sing Sing; Davenport, Miles P; Nikolich-Zugich, Janko 2010. Diversity of the CD8+ T cell repertoire elicited against an immunodominant epitope does not depend on the context of infection. Journal of immunology (Baltimore, Md. : 1950), 184 6, 2958-65Winstead, Colleen J; Reilly, Cavan S; Moon, James J; Jenkins, Marc K; Hamilton, Sara E; Jameson, Stephen C; Way, Sing Sing; Khoruts, Alexander 2010. CD4+CD25+Foxp3+ regulatory T cells optimize diversity of the conventional T cell repertoire during reconstitution from lymphopenia. Journal of immunology (Baltimore, Md. : 1950), 184 9, 4749-60Curtis, Meredith M; Way, Sing Sing 2009. Interleukin-17 in host defence against bacterial, mycobacterial and fungal pathogens. Immunology, 126 2, 177-85Curtis, Meredith M; Way, Sing Sing; Wilson, Christopher B 2009. IL-23 promotes the production of IL-17 by antigen-specific CD8 T cells in the absence of IL-12 and type-I interferons. Journal of immunology (Baltimore, Md. : 1950), 183 1, 381-7Ertelt, James M; Rowe, Jared H; Johanns, Tanner M; Lai, Joseph C; McLachlan, James B; Way, Sing Sing 2009. Selective priming and expansion of antigen-specific Foxp3- CD4+ T cells during Listeria monocytogenes infection. Journal of immunology (Baltimore, Md. : 1950), 182 5, 3032-8Rowe, Jared H; Johanns, Tanner M; Ertelt, James M; Lai, Joseph C; Way, Sing Sing 2009. Cytotoxic T-lymphocyte antigen 4 blockade augments the T-cell response primed by attenuated Listeria monocytogenes resulting in more rapid clearance of virulent bacterial challenge. Immunology, 128 1 Suppl, e471-8Asplin, Iain R; Carl, David J; Way, Sing Sing; Jones, Amanda L 2008. Role of Toll-like receptor 2 in innate resistance to Group B Streptococcus. Microbial pathogenesis, 44 1, 43-51Muller, William J; Orgun, Nural N; Dong, Lichun; Koelle, David M; Huang, Meei-Li; Way, Sing Sing 2008. Recombinant Listeria monocytogenes expressing an immunodominant peptide fails to protect after intravaginal challenge with herpes simplex virus-2. Archives of virology, 153 6, 1165-9Orgun, Nural N; Mathis, Meredith A; Wilson, Christopher B; Way, Sing Sing 2008. Deviation from a strong Th1-dominated to a modest Th17-dominated CD4 T cell response in the absence of IL-12p40 and type I IFNs sustains protective CD8 T cells. Journal of immunology (Baltimore, Md. : 1950), 180 6, 4109-15Orgun, Nural N; Way, Sing Sing 2008. A critical role for phospholipase C in protective immunity conferred by listeriolysin O-deficient Listeria monocytogenes. Microbial pathogenesis, 44 2, 159-63Rowe, Jared H; Johanns, Tanner M; Ertelt, James M; Way, Sing Sing 2008. PDL-1 blockade impedes T cell expansion and protective immunity primed by attenuated Listeria monocytogenes. Journal of immunology (Baltimore, Md. : 1950), 180 11, 7553-7Kollmann, Tobias R; Reikie, Brian; Blimkie, Darren; Way, Sing Sing; Hajjar, Adeline M; Arispe, Kiea; Shaulov, Angela; Wilson, Christopher B 2007. Induction of protective immunity to Listeria monocytogenes in neonates. Journal of immunology (Baltimore, Md. : 1950), 178 6, 3695-701Orr, Mark T; Orgun, Nural N; Wilson, Christopher B; Way, Sing Sing 2007. Cutting edge: recombinant Listeria monocytogenes expressing a single immune-dominant peptide confers protective immunity to herpes simplex virus-1 infection. Journal of immunology (Baltimore, Md. : 1950), 178 8, 4731-5Way, Sing Sing; Havenar-Daughton, Colin; Kolumam, Ganesh A; Orgun, Nural N; Murali-Krishna, Kaja 2007. IL-12 and type-I IFN synergize for IFN-gamma production by CD4 T cells, whereas neither are required for IFN-gamma production by CD8 T cells after Listeria monocytogenes infection. Journal of immunology (Baltimore, Md. : 1950), 178 7, 4498-505Way, Sing Sing; Wilson, Christopher B 2005. The Mycobacterium tuberculosis ESAT-6 homologue in Listeria monocytogenes is dispensable for growth in vitro and in vivo. Infection and immunity, 73 9, 6151-3Darveau, Richard P; Pham, Thu-Thao T; Lemley, Kayde; Reife, Robert A; Bainbridge, Brian W; Coats, Stephen R; Howald, William N; Way, Sing Sing; Hajjar, Adeline M 2004. Porphyromonas gingivalis lipopolysaccharide contains multiple lipid A species that functionally interact with both toll-like receptors 2 and 4. Infection and immunity, 72 9, 5041-51Kollmann, Tobias R; Way, Sing Sing; Harowicz, Heidi L; Hajjar, Adeline M; Wilson, Christopher B 2004. Deficient MHC class I cross-presentation of soluble antigen by murine neonatal dendritic cells. Blood, 103 11, 4240-2Way, Sing Sing; Thompson, Lucas J; Lopes, Jared E; Hajjar, Adeline M; Kollmann, Tobias R; Freitag, Nancy E; Wilson, Christopher B 2004. Characterization of flagellin expression and its role in Listeria monocytogenes infection and immunity. Cellular microbiology, 6 3, 235-42Way, Sing Sing; Wilson, Christopher B 2004. Cutting edge: immunity and IFN-gamma production during Listeria monocytogenes infection in the absence of T-bet. Journal of immunology (Baltimore, Md. : 1950), 173 10, 5918-22Shetron-Rama, Lynne M; Mueller, Kimberly; Bravo, Juan M; Bouwer, H G Archie; Way, Sing Sing; Freitag, Nancy E 2003. Isolation of Listeria monocytogenes mutants with high-level in vitro expression of host cytosol-induced gene products. Molecular microbiology, 48 6, 1537-51Way, Sing Sing; Kollmann, Tobias R; Hajjar, Adeline M; Wilson, Christopher B 2003. Cutting edge: protective cell-mediated immunity to Listeria monocytogenes in the absence of myeloid differentiation factor 88. Journal of immunology (Baltimore, Md. : 1950), 171 2, 533-7Kinder, Jeremy M; Jiang, Tony T; Clark, Dayna R; Chaturvedi, Vandana; Xin, Lijun; Ertelt, James M; Way, Sing Sing . Pregnancy-induced maternal regulatory T cells, bona fide memory or maintenance by antigenic reminder from fetal cell microchimerism? Chimerism, 5 1, 16-9
Research InterestsI work in infectious disease pediatrics because I love kids and I love taking care of them. Patients are the most vulnerable during infancy and early life development, which means they need advocates for their health. My research interests include infectious diseases, reproductive biology, developmental biology and immunology. I was attracted to my research when I became frustrated with not being able to tell parents why their child became sick and how to prevent their illness in the future...
Peer Reviewed Publications Erickson, John J; Archer-Hartmann, Stephanie; Yarawsky, Alexander E; Miller, Jeanette L C; Seveau, Stephanie; Shao, Tzu-Yu; Severance, Ashley L; Miller-Handley, Hilary; Wu, Yuehong; Pham, Giang; Wasik, Brian R; Parrish, Colin R; Hu, Yueh-Chiang; Lau, Joseph T Y; Azadi, Parastoo; Herr, Andrew B; Way, Sing Sing 2022. Pregnancy enables antibody protection against intracellular infection. Nature, 606 7915, 769-775McDaniel, Margaret M; Chawla, Amanpreet Singh; Jain, Aakanksha; Meibers, Hannah E; Saha, Irene; Gao, Yajing; Jain, Viral; Roskin, Krishna; Way, Sing Sing; Pasare, Chandrashekhar 2022. Effector memory CD4+ T cells induce damaging innate inflammation and autoimmune pathology by engaging CD40 and TNFR on myeloid cells. Science immunology, 7 67, eabk0182Severance, Ashley L; Kinder, Jeremy M; Xin, Lijun; Burg, Ashley R; Shao, Tzu-Yu; Pham, Giang; Tilburgs, Tamara; Goodman, Wendy A; Mesiano, Sam; Way, Sing Sing 2022. Maternal-fetal conflict averted by progesterone- induced FOXP3+ regulatory T cells. iScience, 25 6, 104400Shao, Tzu-Yu; Kakade, Pallavi; Witchley, Jessica N; Frazer, Corey; Murray, Kathryn L; Ene, Iuliana V; Haslam, David B; Hagan, Thomas; Noble, Suzanne M; Bennett, Richard J; Way, Sing Sing 2022. Candida albicans oscillating UME6 expression during intestinal colonization primes systemic Th17 protective immunity. Cell reports, 39 7, 110837Alarcon, Pablo C; Damen, Michelle S M A; Madan, Rajat; Deepe, George S; Spearman, Paul; Way, Sing Sing; Divanovic, Senad 2021. Adipocyte inflammation and pathogenesis of viral pneumonias: an overlooked contribution. Mucosal immunology, 14 6, 1224-1234Bianchi, Diana W; Khosrotehrani, Kiarash; Way, Sing Sing; MacKenzie, Tippi C; Bajema, Ingeborg; O'Donoghue, Keelin 2021. Forever Connected: The Lifelong Biological Consequences of Fetomaternal and Maternofetal Microchimerism. Clinical chemistry, 67 2, 351-362Cappelletti, Monica; Presicce, Pietro; Feiyang, Ma; Senthamaraikannan, Paranthaman; Miller, Lisa A; Pellegrini, Matteo; Sim, Myung S; Jobe, Alan H; Divanovic, Senad; Way, Sing Sing; Chougnet, Claire A; Kallapur, Suhas G 2021. The induction of preterm labor in rhesus macaques is determined by the strength of immune response to intrauterine infection. PLoS biology, 19 9, e3001385Chen, Didi; Burford, Wesley B; Pham, Giang; Zhang, Lishu; Alto, Laura T; Ertelt, James M; Winter, Maria G; Winter, Sebastian E; Way, Sing Sing; Alto, Neal M 2021. Systematic reconstruction of an effector-gene network reveals determinants of Salmonella cellular and tissue tropism. Cell host & microbe, 29 10, 1531-1544.e9Gregory, Emily J; Liu, James; Miller-Handley, Hilary; Kinder, Jeremy M; Way, Sing Sing 2021. Epidemiology of Pregnancy Complications Through the Lens of Immunological Memory. Frontiers in immunology, 12 , 693189Miller-Handley, Hilary; Erickson, John J; Gregory, Emily J; Prasanphanich, Nina Salinger; Shao, Tzu-Yu; Way, Sing Sing 2021. Tacrolimus exposure windows responsible for Listeria monocytogenes infection susceptibility. Transplant infectious disease : an official journal of the Transplantation Society, 23 4, e13655Prasanphanich, Nina Salinger; Gregory, Emily J; Erickson, John J; Miller-Handley, Hilary; Kinder, Jeremy M; Way, Sing Sing 2021. Preconceptual Priming Overrides Susceptibility to Escherichia coli Systemic Infection during Pregnancy. mBio, 12 1, Zhang, Jizhou; Wu, Qingqing; Johnson, Courtney B; Pham, Giang; Kinder, Jeremy M; Olsson, Andre; Slaughter, Anastasiya; May, Margot; Weinhaus, Benjamin; D'Alessandro, Angelo; Engel, James Douglas; Jiang, Jean X; Kofron, J Matthew; Huang, L Frank; Prasath, V B Surya; Way, Sing Sing; Salomonis, Nathan; Grimes, H Leighton; Lucas, Daniel 2021. In situ mapping identifies distinct vascular niches for myelopoiesis. Nature, 590 7846, 457-462Almanan, Maha; Raynor, Jana; Ogunsulire, Ireti; Malyshkina, Anna; Mukherjee, Shibabrata; Hummel, Sarah A; Ingram, Jennifer T; Saini, Ankur; Xie, Markus M; Alenghat, Theresa; Way, Sing Sing; Deepe, George S; Divanovic, Senad; Singh, Harinder; Miraldi, Emily; Zajac, Allan J; Dent, Alexander L; Hölscher, Christoph; Chougnet, Claire; Hildeman, David A 2020. IL-10-producing Tfh cells accumulate with age and link inflammation with age-related immune suppression. Science advances, 6 31, eabb0806Burg, Ashley R; Erickson, John J; Turner, Lucien H; Pham, Giang; Kinder, Jeremy M; Way, Sing Sing 2020. Persistent Zika Virus Clinical Susceptibility despite Reduced Viral Burden in Mice with Expanded Virus-Specific CD8+ T Cells Primed by Recombinant Listeria monocytogenes. Journal of immunology (Baltimore, Md. : 1950), 205 2, 447-453Chen, Yee-Shiuan; Chen, Iuan-Bor; Pham, Giang; Shao, Tzu-Yu; Bangar, Hansraj; Way, Sing Sing; Haslam, David B 2020. IL-17-producing ?? T cells protect against Clostridium difficile infection. The Journal of clinical investigation, 130 5, 2377-2390Kinder, Jeremy M; Turner, Lucien H; Stelzer, Ina A; Miller-Handley, Hilary; Burg, Ashley; Shao, Tzu-Yu; Pham, Giang; Way, Sing Sing 2020. CD8+ T Cell Functional Exhaustion Overrides Pregnancy-Induced Fetal Antigen Alloimmunization. Cell reports, 31 12, 107784Kollmann, Tobias R; Marchant, Arnaud; Way, Sing Sing 2020. Vaccination strategies to enhance immunity in neonates. Science (New York, N.Y.), 368 6491, 612-615Muench, David E; Olsson, Andre; Ferchen, Kyle; Pham, Giang; Serafin, Rachel A; Chutipongtanate, Somchai; Dwivedi, Pankaj; Song, Baobao; Hay, Stuart; Chetal, Kashish; Trump-Durbin, Lisa R; Mookerjee-Basu, Jayati; Zhang, Kejian; Yu, Jennifer C; Lutzko, Carolyn; Myers, Kasiani C; Nazor, Kristopher L; Greis, Kenneth D; Kappes, Dietmar J; Way, Sing Sing; Salomonis, Nathan; Grimes, H Leighton 2020. Mouse models of neutropenia reveal progenitor-stage-specific defects. Nature, 582 7810, 109-114Yang, Li; Shivakumar, Pranavkumar; Kinder, Jeremy; Way, Sing Sing; Donnelly, Bryan; Mourya, Reena; Luo, Zhenhua; Bezerra, Jorge A 2020. Regulation of bile duct epithelial injury by hepatic CD71+ erythroid cells. JCI insight, 5 11, Aggor, Felix E Y; Way, Sing Sing; Gaffen, Sarah L 2019. Fungus Among Us: The Frenemies Within. Trends in immunology, 40 6, 469-471Deshmukh, Hitesh; Way, Sing Sing 2019. Immunological Basis for Recurrent Fetal Loss and Pregnancy Complications. Annual review of pathology, 14 , 185-210Kotov, Dmitri I; Mitchell, Jason S; Pengo, Thomas; Ruedl, Christiane; Way, Sing Sing; Langlois, Ryan A; Fife, Brian T; Jenkins, Marc K 2019. TCR Affinity Biases Th Cell Differentiation by Regulating CD25, Eef1e1, and Gbp2. Journal of immunology (Baltimore, Md. : 1950), 202 9, 2535-2545Shao, Tzu-Yu; Ang, W X Gladys; Jiang, Tony T; Huang, Felicia Scaggs; Andersen, Heidi; Kinder, Jeremy M; Pham, Giang; Burg, Ashley R; Ruff, Brandy; Gonzalez, Tammy; Khurana Hershey, Gurjit K; Haslam, David B; Way, Sing Sing 2019. Commensal Candida albicans Positively Calibrates Systemic Th17 Immunological Responses. Cell host & microbe, 25 3, 404-417.e6Deshpande, Neha R; Uhrlaub, Jennifer L; Way, Sing Sing; Nikolich-Žugich, Janko; Kuhns, Michael S 2018. A disconnect between precursor frequency, expansion potential, and site-specific CD4+ T cell responses in aged mice. PloS one, 13 6, e0198354DiToro, Daniel; Winstead, Colleen J; Pham, Duy; Witte, Steven; Andargachew, Rakieb; Singer, Jeffrey R; Wilson, C Garrett; Zindl, Carlene L; Luther, Rita J; Silberger, Daniel J; Weaver, Benjamin T; Kolawole, E Motunrayo; Martinez, Ryan J; Turner, Henrietta; Hatton, Robin D; Moon, James J; Way, Sing Sing; Evavold, Brian D; Weaver, Casey T 2018. Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells. Science (New York, N.Y.), 361 6407, Schlaudecker, Elizabeth P; Ambroggio, Lilliam; McNeal, Monica M; Finkelman, Fred D; Way, Sing Sing 2018. Declining responsiveness to influenza vaccination with progression of human pregnancy. Vaccine, 36 31, 4734-4741Yang, Jason D; Mott, Daniel; Sutiwisesak, Rujapak; Lu, Yu-Jung; Raso, Fiona; Stowell, Britni; Babunovic, Greg Hunter; Lee, Jinhee; Carpenter, Steve M; Way, Sing Sing; Fortune, Sarah M; Behar, Samuel M 2018. Mycobacterium tuberculosis-specific CD4+ and CD8+ T cells differ in their capacity to recognize infected macrophages. PLoS pathogens, 14 5, e1007060Zhou, Jordan Z; Way, Sing Sing; Chen, Kang 2018. Immunology of Uterine and Vaginal Mucosae: (Trends in Immunology 39, 302-314, 2018). Trends in immunology, 39 4, 355Zhou, Jordan Z; Way, Sing Sing; Chen, Kang 2018. Immunology of the Uterine and Vaginal Mucosae. Trends in immunology, 39 4, 302-314Cappelletti, Monica; Presicce, Pietro; Lawson, Matthew J; Chaturvedi, Vandana; Stankiewicz, Traci E; Vanoni, Simone; Harley, Isaac Tw; McAlees, Jaclyn W; Giles, Daniel A; Moreno-Fernandez, Maria E; Rueda, Cesar M; Senthamaraikannan, Paranth; Sun, Xiaofei; Karns, Rebekah; Hoebe, Kasper; Janssen, Edith M; Karp, Christopher L; Hildeman, David A; Hogan, Simon P; Kallapur, Suhas G; Chougnet, Claire A; Way, Sing Sing; Divanovic, Senad 2017. Type I interferons regulate susceptibility to inflammation-induced preterm birth. JCI insight, 2 5, e91288Jiang, Tony T; Shao, Tzu-Yu; Ang, W X Gladys; Kinder, Jeremy M; Turner, Lucien H; Pham, Giang; Whitt, Jordan; Alenghat, Theresa; Way, Sing Sing 2017. Commensal Fungi Recapitulate the Protective Benefits of Intestinal Bacteria. Cell host & microbe, 22 6, 809-816.e4Kinder, Jeremy M; Stelzer, Ina A; Arck, Petra C; Way, Sing Sing 2017. Reply: Breastfeeding-related maternal microchimerism. Nature reviews. Immunology, 17 11, 730-1Kinder, Jeremy M; Stelzer, Ina A; Arck, Petra C; Way, Sing Sing 2017. Immunological implications of pregnancy-induced microchimerism. Nature reviews. Immunology, 17 8, 483-494Lange, Shannon M; McKell, Melanie C; Schmidt, Stephanie M; Hossfeld, Austin P; Chaturvedi, Vandana; Kinder, Jeremy M; McAlees, Jaclyn W; Lewkowich, Ian P; Way, Sing Sing; Turner, Joanne; Qualls, Joseph E 2017. l-Citrulline Metabolism in Mice Augments CD4+ T Cell Proliferation and Cytokine Production In Vitro, and Accumulation in the Mycobacteria-Infected Lung. Frontiers in immunology, 8 , 1561Navabi, Nazanin; Whitt, Jordan; Wu, Shu-En; Woo, Vivienne; Moncivaiz, Jessica; Jordan, Michael B; Vallance, Bruce A; Way, Sing Sing; Alenghat, Theresa 2017. Epithelial Histone Deacetylase 3 Instructs Intestinal Immunity by Coordinating Local Lymphocyte Activation. Cell reports, 19 6, 1165-1175Turner, Lucien H; Kinder, Jeremy M; Wilburn, Adrienne; D'Mello, Rahul J; Braunlin, Makayla R; Jiang, Tony T; Pham, Giang; Way, Sing Sing 2017. Preconceptual Zika virus asymptomatic infection protects against secondary prenatal infection. PLoS pathogens, 13 11, e1006684Carpenter, Stephen M; Nunes-Alves, Cláudio; Booty, Matthew G; Way, Sing Sing; Behar, Samuel M 2016. A Higher Activation Threshold of Memory CD8+ T Cells Has a Fitness Cost That Is Modified by TCR Affinity during Tuberculosis. PLoS pathogens, 12 1, e1005380Jiang, Tony T; Martinov, Tijana; Xin, Lijun; Kinder, Jeremy M; Spanier, Justin A; Fife, Brian T; Way, Sing Sing 2016. Programmed Death-1 Culls Peripheral Accumulation of High-Affinity Autoreactive CD4 T Cells to Protect against Autoimmunity. Cell reports, 17 7, 1783-1794Johnson, Lexus R; Weizman, Orr-El; Rapp, Moritz; Way, Sing Sing; Sun, Joseph C 2016. Epitope-Specific Vaccination Limits Clonal Expansion of Heterologous Naive T Cells during Viral Challenge. Cell reports, 17 3, 636-644Kinder, Jeremy M; Jiang, Tony T; Way, Sing Sing 2016. Offspring's Tolerance of Mother Goes Viral. Immunity, 44 5, 1085-7Rosenblum, Michael D; Way, Sing Sing; Abbas, Abul K 2016. Regulatory T cell memory. Nature reviews. Immunology, 16 2, 90-101Chaturvedi, Vandana; Ertelt, James M; Jiang, Tony T; Kinder, Jeremy M; Xin, Lijun; Owens, Kathryn J; Jones, Helen N; Way, Sing Sing 2015. CXCR3 blockade protects against Listeria monocytogenes infection-induced fetal wastage. The Journal of clinical investigation, 125 4, 1713-25Kinder, Jeremy M; Jiang, Tony T; Ertelt, James M; Xin, Lijun; Strong, Beverly S; Shaaban, Aimen F; Way, Sing Sing 2015. Cross-Generational Reproductive Fitness Enforced by Microchimeric Maternal Cells. Cell, 162 3, 505-15Kinder, Jeremy M; Jiang, Tony T; Ertelt, James M; Xin, Lijun; Strong, Beverly S; Shaaban, Aimen F; Way, Sing Sing 2015. Tolerance to noninherited maternal antigens, reproductive microchimerism and regulatory T cell memory: 60 years after 'Evidence for actively acquired tolerance to Rh antigens'. Chimerism, 6 1-2, 8-20Legoux, Francois P; Lim, Jong-Baeck; Cauley, Andrew W; Dikiy, Stanislav; Ertelt, James; Mariani, Thomas J; Sparwasser, Tim; Way, Sing Sing; Moon, James J 2015. CD4+ T Cell Tolerance to Tissue-Restricted Self Antigens Is Mediated by Antigen-Specific Regulatory T Cells Rather Than Deletion. Immunity, 43 5, 896-908Nanton, Minelva R; Lee, Seung-Joo; Atif, Shaikh M; Nuccio, Sean-Paul; Taylor, Justin J; Bäumler, Andreas J; Way, Sing Sing; McSorley, Stephen J 2015. Direct visualization of endogenous Salmonella-specific B cells reveals a marked delay in clonal expansion and germinal center development. European journal of immunology, 45 2, 428-41PrabhuDas, Mercy; Bonney, Elizabeth; Caron, Kathleen; Dey, Sudhansu; Erlebacher, Adrian; Fazleabas, Asgerally; Fisher, Susan; Golos, Thaddeus; Matzuk, Martin; McCune, Joseph M; Mor, Gil; Schulz, Laura; Soares, Michael; Spencer, Thomas; Strominger, Jack; Way, Sing Sing; Yoshinaga, Koji 2015. Immune mechanisms at the maternal-fetal interface: perspectives and challenges. Nature immunology, 16 4, 328-34Xin, Lijun; Jiang, Tony T; Kinder, Jeremy M; Ertelt, James M; Way, Sing Sing 2015. Infection susceptibility and immune senescence with advancing age replicated in accelerated aging Lmna(Dhe) mice. Aging cell, , Clark, Dayna R; Chaturvedi, Vandana; Kinder, Jeremy M; Jiang, Tony T; Xin, Lijun; Ertelt, James M; Way, Sing Sing 2014. Perinatal Listeria monocytogenes susceptibility despite preconceptual priming and maintenance of pathogen-specific CD8(+) T cells during pregnancy. Cellular & molecular immunology, 11 6, 595-605Drummond, Rebecca A; Wallace, Carol; Reid, Delyth M; Way, Sing Sing; Kaplan, Daniel H; Brown, Gordon D 2014. Cutting edge: Failure of antigen-specific CD4+ T cell recruitment to the kidney during systemic candidiasis. Journal of immunology (Baltimore, Md. : 1950), 193 11, 5381-5Jiang, Tony T; Chaturvedi, Vandana; Ertelt, James M; Kinder, Jeremy M; Clark, Dayna R; Valent, Amy M; Xin, Lijun; Way, Sing Sing 2014. Regulatory T cells: new keys for further unlocking the enigma of fetal tolerance and pregnancy complications. Journal of immunology (Baltimore, Md. : 1950), 192 11, 4949-56Xin, Lijun; Ertelt, James M; Rowe, Jared H; Jiang, Tony T; Kinder, Jeremy M; Chaturvedi, Vandana; Elahi, Shokrollah; Way, Sing Sing 2014. Cutting edge: committed Th1 CD4+ T cell differentiation blocks pregnancy-induced Foxp3 expression with antigen-specific fetal loss. Journal of immunology (Baltimore, Md. : 1950), 192 7, 2970-4Xin, Lijun; Jiang, Tony T; Chaturvedi, Vandana; Kinder, Jeremy M; Ertelt, James M; Rowe, Jared H; Steinbrecher, Kris A; Way, Sing Sing 2014. Commensal microbes drive intestinal inflammation by IL-17-producing CD4+ T cells through ICOSL and OX40L costimulation in the absence of B7-1 and B7-2. Proceedings of the National Academy of Sciences of the United States of America, 111 29, 10672-7Burnaevskiy, Nikolay; Fox, Thomas G; Plymire, Daniel A; Ertelt, James M; Weigele, Bethany A; Selyunin, Andrey S; Way, Sing Sing; Patrie, Steven M; Alto, Neal M 2013. Proteolytic elimination of N-myristoyl modifications by the Shigella virulence factor IpaJ. Nature, 496 7443, 106-9Elahi, Shokrollah; Ertelt, James M; Kinder, Jeremy M; Jiang, Tony T; Zhang, Xuzhe; Xin, Lijun; Chaturvedi, Vandana; Strong, Beverly S; Qualls, Joseph E; Steinbrecher, Kris A; Kalfa, Theodosia A; Shaaban, Aimen F; Way, Sing Sing 2013. Immunosuppressive CD71+ erythroid cells compromise neonatal host defence against infection. Nature, 504 7478, 158-62Ertelt, James M; Buyukbasaran, Esra Z; Jiang, Tony T; Rowe, Jared H; Xin, Lijun; Way, Sing Sing 2013. B7-1/B7-2 blockade overrides the activation of protective CD8 T cells stimulated in the absence of Foxp3+ regulatory T cells. Journal of leukocyte biology, 94 2, 367-76Rowe, Jared H; Ertelt, James M; Xin, Lijun; Way, Sing Sing 2013. Regulatory T cells and the immune pathogenesis of prenatal infection. Reproduction (Cambridge, England), 146 6, R191-203Shafiani, Shahin; Dinh, Crystal; Ertelt, James M; Moguche, Albanus O; Siddiqui, Imran; Smigiel, Kate S; Sharma, Pawan; Campbell, Daniel J; Way, Sing Sing; Urdahl, Kevin B 2013. Pathogen-specific Treg cells expand early during mycobacterium tuberculosis infection but are later eliminated in response to Interleukin-12. Immunity, 38 6, 1261-70Tubo, Noah J; Pagán, Antonio J; Taylor, Justin J; Nelson, Ryan W; Linehan, Jonathan L; Ertelt, James M; Huseby, Eric S; Way, Sing Sing; Jenkins, Marc K 2013. Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection. Cell, 153 4, 785-96Kanistanon, Duangjit; Powell, Daniel A; Hajjar, Adeline M; Pelletier, Mark R; Cohen, Ilana E; Way, Sing Sing; Skerrett, Shawn J; Wang, Xiaoyuan; Raetz, Christian R H; Ernst, Robert K 2012. Role of Francisella lipid A phosphate modification in virulence and long-term protective immune responses. Infection and immunity, 80 3, 943-51Nanton, Minelva R; Way, Sing Sing; Shlomchik, Mark J; McSorley, Stephen J 2012. Cutting edge: B cells are essential for protective immunity against Salmonella independent of antibody secretion. Journal of immunology (Baltimore, Md. : 1950), 189 12, 5503-7Rowe, Jared H; Ertelt, James M; Way, Sing Sing 2012. Innate IFN-? is essential for programmed death ligand-1-mediated T cell stimulation following Listeria monocytogenes infection. Journal of immunology (Baltimore, Md. : 1950), 189 2, 876-84Rowe, Jared H; Ertelt, James M; Way, Sing Sing 2012. Foxp3(+) regulatory T cells, immune stimulation and host defence against infection. Immunology, 136 1, 1-10Rowe, Jared H; Ertelt, James M; Xin, Lijun; Way, Sing Sing 2012. Pregnancy imprints regulatory memory that sustains anergy to fetal antigen. Nature, 490 7418, 102-6Rowe, Jared H; Ertelt, James M; Xin, Lijun; Way, Sing Sing 2012. Listeria monocytogenes cytoplasmic entry induces fetal wastage by disrupting maternal Foxp3+ regulatory T cell-sustained fetal tolerance. PLoS pathogens, 8 8, e1002873Ertelt, James M; Johanns, Tanner M; Mysz, Margaret A; Nanton, Minelva R; Rowe, Jared H; Aguilera, Marijo N; Way, Sing Sing 2011. Selective culling of high avidity antigen-specific CD4+ T cells after virulent Salmonella infection. Immunology, 134 4, 487-97Ertelt, James M; Rowe, Jared H; Mysz, Margaret A; Singh, Charanjeet; Roychowdhury, Monika; Aguilera, Marijo N; Way, Sing Sing 2011. Foxp3+ regulatory T cells impede the priming of protective CD8+ T cells. Journal of immunology (Baltimore, Md. : 1950), 187 5, 2569-77Han, Jin-Young; Hanson, David C; Way, Sing Sing 2011. Herpes zoster and meningitis due to reactivation of varicella vaccine virus in an immunocompetent child. The Pediatric infectious disease journal, 30 3, 266-8Johanns, Tanner M; Law, Calvin Y; Kalekar, Lokeshchandra A; O'Donnell, Hope; Ertelt, James M; Rowe, Jared H; Way, Sing Sing 2011. Early eradication of persistent Salmonella infection primes antibody-mediated protective immunity to recurrent infection. Microbes and infection / Institut Pasteur, 13 4, 322-30Rowe, Jared H; Ertelt, James M; Aguilera, Marijo N; Farrar, Michael A; Way, Sing Sing 2011. Foxp3(+) regulatory T cell expansion required for sustaining pregnancy compromises host defense against prenatal bacterial pathogens. Cell host & microbe, 10 1, 54-64Rudd, Brian D; Venturi, Vanessa; Li, Gang; Samadder, Partha; Ertelt, James M; Way, Sing Sing; Davenport, Miles P; Nikolich-Žugich, Janko 2011. Nonrandom attrition of the naive CD8+ T-cell pool with aging governed by T-cell receptor:pMHC interactions. Proceedings of the National Academy of Sciences of the United States of America, 108 33, 13694-9Curtis, Meredith M; Rowell, Emily; Shafiani, Shahin; Negash, Amina; Urdahl, Kevin B; Wilson, Christopher B; Way, Sing Sing 2010. Fidelity of pathogen-specific CD4+ T cells to the Th1 lineage is controlled by exogenous cytokines, interferon-gamma expression, and pathogen lifestyle. Cell host & microbe, 8 2, 163-73Ertelt, James M; Johanns, Tanner M; Rowe, Jared H; Way, Sing Sing 2010. Interleukin (IL)-21-independent pathogen-specific CD8+ T-cell expansion, and IL-21-dependent suppression of CD4+ T-cell IL-17 production. Immunology, 131 2, 183-91Johanns, Tanner M; Ertelt, James M; Lai, Joseph C; Rowe, Jared H; Avant, Ross A; Way, Sing Sing 2010. Naturally occurring altered peptide ligands control Salmonella-specific CD4+ T cell proliferation, IFN-gamma production, and protective potency. Journal of immunology (Baltimore, Md. : 1950), 184 2, 869-76Johanns, Tanner M; Ertelt, James M; Rowe, Jared H; Way, Sing Sing 2010. Regulatory T cell suppressive potency dictates the balance between bacterial proliferation and clearance during persistent Salmonella infection. PLoS pathogens, 6 8, e1001043Rudd, Brian D; Venturi, Vanessa; Smithey, Megan J; Way, Sing Sing; Davenport, Miles P; Nikolich-Zugich, Janko 2010. Diversity of the CD8+ T cell repertoire elicited against an immunodominant epitope does not depend on the context of infection. Journal of immunology (Baltimore, Md. : 1950), 184 6, 2958-65Winstead, Colleen J; Reilly, Cavan S; Moon, James J; Jenkins, Marc K; Hamilton, Sara E; Jameson, Stephen C; Way, Sing Sing; Khoruts, Alexander 2010. CD4+CD25+Foxp3+ regulatory T cells optimize diversity of the conventional T cell repertoire during reconstitution from lymphopenia. Journal of immunology (Baltimore, Md. : 1950), 184 9, 4749-60Curtis, Meredith M; Way, Sing Sing 2009. Interleukin-17 in host defence against bacterial, mycobacterial and fungal pathogens. Immunology, 126 2, 177-85Curtis, Meredith M; Way, Sing Sing; Wilson, Christopher B 2009. IL-23 promotes the production of IL-17 by antigen-specific CD8 T cells in the absence of IL-12 and type-I interferons. Journal of immunology (Baltimore, Md. : 1950), 183 1, 381-7Ertelt, James M; Rowe, Jared H; Johanns, Tanner M; Lai, Joseph C; McLachlan, James B; Way, Sing Sing 2009. Selective priming and expansion of antigen-specific Foxp3- CD4+ T cells during Listeria monocytogenes infection. Journal of immunology (Baltimore, Md. : 1950), 182 5, 3032-8Rowe, Jared H; Johanns, Tanner M; Ertelt, James M; Lai, Joseph C; Way, Sing Sing 2009. Cytotoxic T-lymphocyte antigen 4 blockade augments the T-cell response primed by attenuated Listeria monocytogenes resulting in more rapid clearance of virulent bacterial challenge. Immunology, 128 1 Suppl, e471-8Asplin, Iain R; Carl, David J; Way, Sing Sing; Jones, Amanda L 2008. Role of Toll-like receptor 2 in innate resistance to Group B Streptococcus. Microbial pathogenesis, 44 1, 43-51Muller, William J; Orgun, Nural N; Dong, Lichun; Koelle, David M; Huang, Meei-Li; Way, Sing Sing 2008. Recombinant Listeria monocytogenes expressing an immunodominant peptide fails to protect after intravaginal challenge with herpes simplex virus-2. Archives of virology, 153 6, 1165-9Orgun, Nural N; Mathis, Meredith A; Wilson, Christopher B; Way, Sing Sing 2008. Deviation from a strong Th1-dominated to a modest Th17-dominated CD4 T cell response in the absence of IL-12p40 and type I IFNs sustains protective CD8 T cells. Journal of immunology (Baltimore, Md. : 1950), 180 6, 4109-15Orgun, Nural N; Way, Sing Sing 2008. A critical role for phospholipase C in protective immunity conferred by listeriolysin O-deficient Listeria monocytogenes. Microbial pathogenesis, 44 2, 159-63Rowe, Jared H; Johanns, Tanner M; Ertelt, James M; Way, Sing Sing 2008. PDL-1 blockade impedes T cell expansion and protective immunity primed by attenuated Listeria monocytogenes. Journal of immunology (Baltimore, Md. : 1950), 180 11, 7553-7Kollmann, Tobias R; Reikie, Brian; Blimkie, Darren; Way, Sing Sing; Hajjar, Adeline M; Arispe, Kiea; Shaulov, Angela; Wilson, Christopher B 2007. Induction of protective immunity to Listeria monocytogenes in neonates. Journal of immunology (Baltimore, Md. : 1950), 178 6, 3695-701Orr, Mark T; Orgun, Nural N; Wilson, Christopher B; Way, Sing Sing 2007. Cutting edge: recombinant Listeria monocytogenes expressing a single immune-dominant peptide confers protective immunity to herpes simplex virus-1 infection. Journal of immunology (Baltimore, Md. : 1950), 178 8, 4731-5Way, Sing Sing; Havenar-Daughton, Colin; Kolumam, Ganesh A; Orgun, Nural N; Murali-Krishna, Kaja 2007. IL-12 and type-I IFN synergize for IFN-gamma production by CD4 T cells, whereas neither are required for IFN-gamma production by CD8 T cells after Listeria monocytogenes infection. Journal of immunology (Baltimore, Md. : 1950), 178 7, 4498-505Way, Sing Sing; Wilson, Christopher B 2005. The Mycobacterium tuberculosis ESAT-6 homologue in Listeria monocytogenes is dispensable for growth in vitro and in vivo. Infection and immunity, 73 9, 6151-3Darveau, Richard P; Pham, Thu-Thao T; Lemley, Kayde; Reife, Robert A; Bainbridge, Brian W; Coats, Stephen R; Howald, William N; Way, Sing Sing; Hajjar, Adeline M 2004. Porphyromonas gingivalis lipopolysaccharide contains multiple lipid A species that functionally interact with both toll-like receptors 2 and 4. Infection and immunity, 72 9, 5041-51Kollmann, Tobias R; Way, Sing Sing; Harowicz, Heidi L; Hajjar, Adeline M; Wilson, Christopher B 2004. Deficient MHC class I cross-presentation of soluble antigen by murine neonatal dendritic cells. Blood, 103 11, 4240-2Way, Sing Sing; Thompson, Lucas J; Lopes, Jared E; Hajjar, Adeline M; Kollmann, Tobias R; Freitag, Nancy E; Wilson, Christopher B 2004. Characterization of flagellin expression and its role in Listeria monocytogenes infection and immunity. Cellular microbiology, 6 3, 235-42Way, Sing Sing; Wilson, Christopher B 2004. Cutting edge: immunity and IFN-gamma production during Listeria monocytogenes infection in the absence of T-bet. Journal of immunology (Baltimore, Md. : 1950), 173 10, 5918-22Shetron-Rama, Lynne M; Mueller, Kimberly; Bravo, Juan M; Bouwer, H G Archie; Way, Sing Sing; Freitag, Nancy E 2003. Isolation of Listeria monocytogenes mutants with high-level in vitro expression of host cytosol-induced gene products. Molecular microbiology, 48 6, 1537-51Way, Sing Sing; Kollmann, Tobias R; Hajjar, Adeline M; Wilson, Christopher B 2003. Cutting edge: protective cell-mediated immunity to Listeria monocytogenes in the absence of myeloid differentiation factor 88. Journal of immunology (Baltimore, Md. : 1950), 171 2, 533-7Kinder, Jeremy M; Jiang, Tony T; Clark, Dayna R; Chaturvedi, Vandana; Xin, Lijun; Ertelt, James M; Way, Sing Sing . Pregnancy-induced maternal regulatory T cells, bona fide memory or maintenance by antigenic reminder from fetal cell microchimerism? Chimerism, 5 1, 16-9
Erickson, John J; Archer-Hartmann, Stephanie; Yarawsky, Alexander E; Miller, Jeanette L C; Seveau, Stephanie; Shao, Tzu-Yu; Severance, Ashley L; Miller-Handley, Hilary; Wu, Yuehong; Pham, Giang; Wasik, Brian R; Parrish, Colin R; Hu, Yueh-Chiang; Lau, Joseph T Y; Azadi, Parastoo; Herr, Andrew B; Way, Sing Sing 2022. Pregnancy enables antibody protection against intracellular infection. Nature, 606 7915, 769-775McDaniel, Margaret M; Chawla, Amanpreet Singh; Jain, Aakanksha; Meibers, Hannah E; Saha, Irene; Gao, Yajing; Jain, Viral; Roskin, Krishna; Way, Sing Sing; Pasare, Chandrashekhar 2022. Effector memory CD4+ T cells induce damaging innate inflammation and autoimmune pathology by engaging CD40 and TNFR on myeloid cells. Science immunology, 7 67, eabk0182Severance, Ashley L; Kinder, Jeremy M; Xin, Lijun; Burg, Ashley R; Shao, Tzu-Yu; Pham, Giang; Tilburgs, Tamara; Goodman, Wendy A; Mesiano, Sam; Way, Sing Sing 2022. Maternal-fetal conflict averted by progesterone- induced FOXP3+ regulatory T cells. iScience, 25 6, 104400Shao, Tzu-Yu; Kakade, Pallavi; Witchley, Jessica N; Frazer, Corey; Murray, Kathryn L; Ene, Iuliana V; Haslam, David B; Hagan, Thomas; Noble, Suzanne M; Bennett, Richard J; Way, Sing Sing 2022. Candida albicans oscillating UME6 expression during intestinal colonization primes systemic Th17 protective immunity. Cell reports, 39 7, 110837Alarcon, Pablo C; Damen, Michelle S M A; Madan, Rajat; Deepe, George S; Spearman, Paul; Way, Sing Sing; Divanovic, Senad 2021. Adipocyte inflammation and pathogenesis of viral pneumonias: an overlooked contribution. Mucosal immunology, 14 6, 1224-1234Bianchi, Diana W; Khosrotehrani, Kiarash; Way, Sing Sing; MacKenzie, Tippi C; Bajema, Ingeborg; O'Donoghue, Keelin 2021. Forever Connected: The Lifelong Biological Consequences of Fetomaternal and Maternofetal Microchimerism. Clinical chemistry, 67 2, 351-362Cappelletti, Monica; Presicce, Pietro; Feiyang, Ma; Senthamaraikannan, Paranthaman; Miller, Lisa A; Pellegrini, Matteo; Sim, Myung S; Jobe, Alan H; Divanovic, Senad; Way, Sing Sing; Chougnet, Claire A; Kallapur, Suhas G 2021. The induction of preterm labor in rhesus macaques is determined by the strength of immune response to intrauterine infection. PLoS biology, 19 9, e3001385Chen, Didi; Burford, Wesley B; Pham, Giang; Zhang, Lishu; Alto, Laura T; Ertelt, James M; Winter, Maria G; Winter, Sebastian E; Way, Sing Sing; Alto, Neal M 2021. Systematic reconstruction of an effector-gene network reveals determinants of Salmonella cellular and tissue tropism. Cell host & microbe, 29 10, 1531-1544.e9Gregory, Emily J; Liu, James; Miller-Handley, Hilary; Kinder, Jeremy M; Way, Sing Sing 2021. Epidemiology of Pregnancy Complications Through the Lens of Immunological Memory. Frontiers in immunology, 12 , 693189Miller-Handley, Hilary; Erickson, John J; Gregory, Emily J; Prasanphanich, Nina Salinger; Shao, Tzu-Yu; Way, Sing Sing 2021. Tacrolimus exposure windows responsible for Listeria monocytogenes infection susceptibility. Transplant infectious disease : an official journal of the Transplantation Society, 23 4, e13655Prasanphanich, Nina Salinger; Gregory, Emily J; Erickson, John J; Miller-Handley, Hilary; Kinder, Jeremy M; Way, Sing Sing 2021. Preconceptual Priming Overrides Susceptibility to Escherichia coli Systemic Infection during Pregnancy. mBio, 12 1, Zhang, Jizhou; Wu, Qingqing; Johnson, Courtney B; Pham, Giang; Kinder, Jeremy M; Olsson, Andre; Slaughter, Anastasiya; May, Margot; Weinhaus, Benjamin; D'Alessandro, Angelo; Engel, James Douglas; Jiang, Jean X; Kofron, J Matthew; Huang, L Frank; Prasath, V B Surya; Way, Sing Sing; Salomonis, Nathan; Grimes, H Leighton; Lucas, Daniel 2021. In situ mapping identifies distinct vascular niches for myelopoiesis. Nature, 590 7846, 457-462Almanan, Maha; Raynor, Jana; Ogunsulire, Ireti; Malyshkina, Anna; Mukherjee, Shibabrata; Hummel, Sarah A; Ingram, Jennifer T; Saini, Ankur; Xie, Markus M; Alenghat, Theresa; Way, Sing Sing; Deepe, George S; Divanovic, Senad; Singh, Harinder; Miraldi, Emily; Zajac, Allan J; Dent, Alexander L; Hölscher, Christoph; Chougnet, Claire; Hildeman, David A 2020. IL-10-producing Tfh cells accumulate with age and link inflammation with age-related immune suppression. Science advances, 6 31, eabb0806Burg, Ashley R; Erickson, John J; Turner, Lucien H; Pham, Giang; Kinder, Jeremy M; Way, Sing Sing 2020. Persistent Zika Virus Clinical Susceptibility despite Reduced Viral Burden in Mice with Expanded Virus-Specific CD8+ T Cells Primed by Recombinant Listeria monocytogenes. Journal of immunology (Baltimore, Md. : 1950), 205 2, 447-453Chen, Yee-Shiuan; Chen, Iuan-Bor; Pham, Giang; Shao, Tzu-Yu; Bangar, Hansraj; Way, Sing Sing; Haslam, David B 2020. IL-17-producing ?? T cells protect against Clostridium difficile infection. The Journal of clinical investigation, 130 5, 2377-2390Kinder, Jeremy M; Turner, Lucien H; Stelzer, Ina A; Miller-Handley, Hilary; Burg, Ashley; Shao, Tzu-Yu; Pham, Giang; Way, Sing Sing 2020. CD8+ T Cell Functional Exhaustion Overrides Pregnancy-Induced Fetal Antigen Alloimmunization. Cell reports, 31 12, 107784Kollmann, Tobias R; Marchant, Arnaud; Way, Sing Sing 2020. Vaccination strategies to enhance immunity in neonates. Science (New York, N.Y.), 368 6491, 612-615Muench, David E; Olsson, Andre; Ferchen, Kyle; Pham, Giang; Serafin, Rachel A; Chutipongtanate, Somchai; Dwivedi, Pankaj; Song, Baobao; Hay, Stuart; Chetal, Kashish; Trump-Durbin, Lisa R; Mookerjee-Basu, Jayati; Zhang, Kejian; Yu, Jennifer C; Lutzko, Carolyn; Myers, Kasiani C; Nazor, Kristopher L; Greis, Kenneth D; Kappes, Dietmar J; Way, Sing Sing; Salomonis, Nathan; Grimes, H Leighton 2020. Mouse models of neutropenia reveal progenitor-stage-specific defects. Nature, 582 7810, 109-114Yang, Li; Shivakumar, Pranavkumar; Kinder, Jeremy; Way, Sing Sing; Donnelly, Bryan; Mourya, Reena; Luo, Zhenhua; Bezerra, Jorge A 2020. Regulation of bile duct epithelial injury by hepatic CD71+ erythroid cells. JCI insight, 5 11, Aggor, Felix E Y; Way, Sing Sing; Gaffen, Sarah L 2019. Fungus Among Us: The Frenemies Within. Trends in immunology, 40 6, 469-471Deshmukh, Hitesh; Way, Sing Sing 2019. Immunological Basis for Recurrent Fetal Loss and Pregnancy Complications. Annual review of pathology, 14 , 185-210Kotov, Dmitri I; Mitchell, Jason S; Pengo, Thomas; Ruedl, Christiane; Way, Sing Sing; Langlois, Ryan A; Fife, Brian T; Jenkins, Marc K 2019. TCR Affinity Biases Th Cell Differentiation by Regulating CD25, Eef1e1, and Gbp2. Journal of immunology (Baltimore, Md. : 1950), 202 9, 2535-2545Shao, Tzu-Yu; Ang, W X Gladys; Jiang, Tony T; Huang, Felicia Scaggs; Andersen, Heidi; Kinder, Jeremy M; Pham, Giang; Burg, Ashley R; Ruff, Brandy; Gonzalez, Tammy; Khurana Hershey, Gurjit K; Haslam, David B; Way, Sing Sing 2019. Commensal Candida albicans Positively Calibrates Systemic Th17 Immunological Responses. Cell host & microbe, 25 3, 404-417.e6Deshpande, Neha R; Uhrlaub, Jennifer L; Way, Sing Sing; Nikolich-Žugich, Janko; Kuhns, Michael S 2018. A disconnect between precursor frequency, expansion potential, and site-specific CD4+ T cell responses in aged mice. PloS one, 13 6, e0198354DiToro, Daniel; Winstead, Colleen J; Pham, Duy; Witte, Steven; Andargachew, Rakieb; Singer, Jeffrey R; Wilson, C Garrett; Zindl, Carlene L; Luther, Rita J; Silberger, Daniel J; Weaver, Benjamin T; Kolawole, E Motunrayo; Martinez, Ryan J; Turner, Henrietta; Hatton, Robin D; Moon, James J; Way, Sing Sing; Evavold, Brian D; Weaver, Casey T 2018. Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells. Science (New York, N.Y.), 361 6407, Schlaudecker, Elizabeth P; Ambroggio, Lilliam; McNeal, Monica M; Finkelman, Fred D; Way, Sing Sing 2018. Declining responsiveness to influenza vaccination with progression of human pregnancy. Vaccine, 36 31, 4734-4741Yang, Jason D; Mott, Daniel; Sutiwisesak, Rujapak; Lu, Yu-Jung; Raso, Fiona; Stowell, Britni; Babunovic, Greg Hunter; Lee, Jinhee; Carpenter, Steve M; Way, Sing Sing; Fortune, Sarah M; Behar, Samuel M 2018. Mycobacterium tuberculosis-specific CD4+ and CD8+ T cells differ in their capacity to recognize infected macrophages. PLoS pathogens, 14 5, e1007060Zhou, Jordan Z; Way, Sing Sing; Chen, Kang 2018. Immunology of Uterine and Vaginal Mucosae: (Trends in Immunology 39, 302-314, 2018). Trends in immunology, 39 4, 355Zhou, Jordan Z; Way, Sing Sing; Chen, Kang 2018. Immunology of the Uterine and Vaginal Mucosae. Trends in immunology, 39 4, 302-314Cappelletti, Monica; Presicce, Pietro; Lawson, Matthew J; Chaturvedi, Vandana; Stankiewicz, Traci E; Vanoni, Simone; Harley, Isaac Tw; McAlees, Jaclyn W; Giles, Daniel A; Moreno-Fernandez, Maria E; Rueda, Cesar M; Senthamaraikannan, Paranth; Sun, Xiaofei; Karns, Rebekah; Hoebe, Kasper; Janssen, Edith M; Karp, Christopher L; Hildeman, David A; Hogan, Simon P; Kallapur, Suhas G; Chougnet, Claire A; Way, Sing Sing; Divanovic, Senad 2017. Type I interferons regulate susceptibility to inflammation-induced preterm birth. JCI insight, 2 5, e91288Jiang, Tony T; Shao, Tzu-Yu; Ang, W X Gladys; Kinder, Jeremy M; Turner, Lucien H; Pham, Giang; Whitt, Jordan; Alenghat, Theresa; Way, Sing Sing 2017. Commensal Fungi Recapitulate the Protective Benefits of Intestinal Bacteria. Cell host & microbe, 22 6, 809-816.e4Kinder, Jeremy M; Stelzer, Ina A; Arck, Petra C; Way, Sing Sing 2017. Reply: Breastfeeding-related maternal microchimerism. Nature reviews. Immunology, 17 11, 730-1Kinder, Jeremy M; Stelzer, Ina A; Arck, Petra C; Way, Sing Sing 2017. Immunological implications of pregnancy-induced microchimerism. Nature reviews. Immunology, 17 8, 483-494Lange, Shannon M; McKell, Melanie C; Schmidt, Stephanie M; Hossfeld, Austin P; Chaturvedi, Vandana; Kinder, Jeremy M; McAlees, Jaclyn W; Lewkowich, Ian P; Way, Sing Sing; Turner, Joanne; Qualls, Joseph E 2017. l-Citrulline Metabolism in Mice Augments CD4+ T Cell Proliferation and Cytokine Production In Vitro, and Accumulation in the Mycobacteria-Infected Lung. Frontiers in immunology, 8 , 1561Navabi, Nazanin; Whitt, Jordan; Wu, Shu-En; Woo, Vivienne; Moncivaiz, Jessica; Jordan, Michael B; Vallance, Bruce A; Way, Sing Sing; Alenghat, Theresa 2017. Epithelial Histone Deacetylase 3 Instructs Intestinal Immunity by Coordinating Local Lymphocyte Activation. Cell reports, 19 6, 1165-1175Turner, Lucien H; Kinder, Jeremy M; Wilburn, Adrienne; D'Mello, Rahul J; Braunlin, Makayla R; Jiang, Tony T; Pham, Giang; Way, Sing Sing 2017. Preconceptual Zika virus asymptomatic infection protects against secondary prenatal infection. PLoS pathogens, 13 11, e1006684Carpenter, Stephen M; Nunes-Alves, Cláudio; Booty, Matthew G; Way, Sing Sing; Behar, Samuel M 2016. A Higher Activation Threshold of Memory CD8+ T Cells Has a Fitness Cost That Is Modified by TCR Affinity during Tuberculosis. PLoS pathogens, 12 1, e1005380Jiang, Tony T; Martinov, Tijana; Xin, Lijun; Kinder, Jeremy M; Spanier, Justin A; Fife, Brian T; Way, Sing Sing 2016. Programmed Death-1 Culls Peripheral Accumulation of High-Affinity Autoreactive CD4 T Cells to Protect against Autoimmunity. Cell reports, 17 7, 1783-1794Johnson, Lexus R; Weizman, Orr-El; Rapp, Moritz; Way, Sing Sing; Sun, Joseph C 2016. Epitope-Specific Vaccination Limits Clonal Expansion of Heterologous Naive T Cells during Viral Challenge. Cell reports, 17 3, 636-644Kinder, Jeremy M; Jiang, Tony T; Way, Sing Sing 2016. Offspring's Tolerance of Mother Goes Viral. Immunity, 44 5, 1085-7Rosenblum, Michael D; Way, Sing Sing; Abbas, Abul K 2016. Regulatory T cell memory. Nature reviews. Immunology, 16 2, 90-101Chaturvedi, Vandana; Ertelt, James M; Jiang, Tony T; Kinder, Jeremy M; Xin, Lijun; Owens, Kathryn J; Jones, Helen N; Way, Sing Sing 2015. CXCR3 blockade protects against Listeria monocytogenes infection-induced fetal wastage. The Journal of clinical investigation, 125 4, 1713-25Kinder, Jeremy M; Jiang, Tony T; Ertelt, James M; Xin, Lijun; Strong, Beverly S; Shaaban, Aimen F; Way, Sing Sing 2015. Cross-Generational Reproductive Fitness Enforced by Microchimeric Maternal Cells. Cell, 162 3, 505-15Kinder, Jeremy M; Jiang, Tony T; Ertelt, James M; Xin, Lijun; Strong, Beverly S; Shaaban, Aimen F; Way, Sing Sing 2015. Tolerance to noninherited maternal antigens, reproductive microchimerism and regulatory T cell memory: 60 years after 'Evidence for actively acquired tolerance to Rh antigens'. Chimerism, 6 1-2, 8-20Legoux, Francois P; Lim, Jong-Baeck; Cauley, Andrew W; Dikiy, Stanislav; Ertelt, James; Mariani, Thomas J; Sparwasser, Tim; Way, Sing Sing; Moon, James J 2015. CD4+ T Cell Tolerance to Tissue-Restricted Self Antigens Is Mediated by Antigen-Specific Regulatory T Cells Rather Than Deletion. Immunity, 43 5, 896-908Nanton, Minelva R; Lee, Seung-Joo; Atif, Shaikh M; Nuccio, Sean-Paul; Taylor, Justin J; Bäumler, Andreas J; Way, Sing Sing; McSorley, Stephen J 2015. Direct visualization of endogenous Salmonella-specific B cells reveals a marked delay in clonal expansion and germinal center development. European journal of immunology, 45 2, 428-41PrabhuDas, Mercy; Bonney, Elizabeth; Caron, Kathleen; Dey, Sudhansu; Erlebacher, Adrian; Fazleabas, Asgerally; Fisher, Susan; Golos, Thaddeus; Matzuk, Martin; McCune, Joseph M; Mor, Gil; Schulz, Laura; Soares, Michael; Spencer, Thomas; Strominger, Jack; Way, Sing Sing; Yoshinaga, Koji 2015. Immune mechanisms at the maternal-fetal interface: perspectives and challenges. Nature immunology, 16 4, 328-34Xin, Lijun; Jiang, Tony T; Kinder, Jeremy M; Ertelt, James M; Way, Sing Sing 2015. Infection susceptibility and immune senescence with advancing age replicated in accelerated aging Lmna(Dhe) mice. Aging cell, , Clark, Dayna R; Chaturvedi, Vandana; Kinder, Jeremy M; Jiang, Tony T; Xin, Lijun; Ertelt, James M; Way, Sing Sing 2014. Perinatal Listeria monocytogenes susceptibility despite preconceptual priming and maintenance of pathogen-specific CD8(+) T cells during pregnancy. Cellular & molecular immunology, 11 6, 595-605Drummond, Rebecca A; Wallace, Carol; Reid, Delyth M; Way, Sing Sing; Kaplan, Daniel H; Brown, Gordon D 2014. Cutting edge: Failure of antigen-specific CD4+ T cell recruitment to the kidney during systemic candidiasis. Journal of immunology (Baltimore, Md. : 1950), 193 11, 5381-5Jiang, Tony T; Chaturvedi, Vandana; Ertelt, James M; Kinder, Jeremy M; Clark, Dayna R; Valent, Amy M; Xin, Lijun; Way, Sing Sing 2014. Regulatory T cells: new keys for further unlocking the enigma of fetal tolerance and pregnancy complications. Journal of immunology (Baltimore, Md. : 1950), 192 11, 4949-56Xin, Lijun; Ertelt, James M; Rowe, Jared H; Jiang, Tony T; Kinder, Jeremy M; Chaturvedi, Vandana; Elahi, Shokrollah; Way, Sing Sing 2014. Cutting edge: committed Th1 CD4+ T cell differentiation blocks pregnancy-induced Foxp3 expression with antigen-specific fetal loss. Journal of immunology (Baltimore, Md. : 1950), 192 7, 2970-4Xin, Lijun; Jiang, Tony T; Chaturvedi, Vandana; Kinder, Jeremy M; Ertelt, James M; Rowe, Jared H; Steinbrecher, Kris A; Way, Sing Sing 2014. Commensal microbes drive intestinal inflammation by IL-17-producing CD4+ T cells through ICOSL and OX40L costimulation in the absence of B7-1 and B7-2. Proceedings of the National Academy of Sciences of the United States of America, 111 29, 10672-7Burnaevskiy, Nikolay; Fox, Thomas G; Plymire, Daniel A; Ertelt, James M; Weigele, Bethany A; Selyunin, Andrey S; Way, Sing Sing; Patrie, Steven M; Alto, Neal M 2013. Proteolytic elimination of N-myristoyl modifications by the Shigella virulence factor IpaJ. Nature, 496 7443, 106-9Elahi, Shokrollah; Ertelt, James M; Kinder, Jeremy M; Jiang, Tony T; Zhang, Xuzhe; Xin, Lijun; Chaturvedi, Vandana; Strong, Beverly S; Qualls, Joseph E; Steinbrecher, Kris A; Kalfa, Theodosia A; Shaaban, Aimen F; Way, Sing Sing 2013. Immunosuppressive CD71+ erythroid cells compromise neonatal host defence against infection. Nature, 504 7478, 158-62Ertelt, James M; Buyukbasaran, Esra Z; Jiang, Tony T; Rowe, Jared H; Xin, Lijun; Way, Sing Sing 2013. B7-1/B7-2 blockade overrides the activation of protective CD8 T cells stimulated in the absence of Foxp3+ regulatory T cells. Journal of leukocyte biology, 94 2, 367-76Rowe, Jared H; Ertelt, James M; Xin, Lijun; Way, Sing Sing 2013. Regulatory T cells and the immune pathogenesis of prenatal infection. Reproduction (Cambridge, England), 146 6, R191-203Shafiani, Shahin; Dinh, Crystal; Ertelt, James M; Moguche, Albanus O; Siddiqui, Imran; Smigiel, Kate S; Sharma, Pawan; Campbell, Daniel J; Way, Sing Sing; Urdahl, Kevin B 2013. Pathogen-specific Treg cells expand early during mycobacterium tuberculosis infection but are later eliminated in response to Interleukin-12. Immunity, 38 6, 1261-70Tubo, Noah J; Pagán, Antonio J; Taylor, Justin J; Nelson, Ryan W; Linehan, Jonathan L; Ertelt, James M; Huseby, Eric S; Way, Sing Sing; Jenkins, Marc K 2013. Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection. Cell, 153 4, 785-96Kanistanon, Duangjit; Powell, Daniel A; Hajjar, Adeline M; Pelletier, Mark R; Cohen, Ilana E; Way, Sing Sing; Skerrett, Shawn J; Wang, Xiaoyuan; Raetz, Christian R H; Ernst, Robert K 2012. Role of Francisella lipid A phosphate modification in virulence and long-term protective immune responses. Infection and immunity, 80 3, 943-51Nanton, Minelva R; Way, Sing Sing; Shlomchik, Mark J; McSorley, Stephen J 2012. Cutting edge: B cells are essential for protective immunity against Salmonella independent of antibody secretion. Journal of immunology (Baltimore, Md. : 1950), 189 12, 5503-7Rowe, Jared H; Ertelt, James M; Way, Sing Sing 2012. Innate IFN-? is essential for programmed death ligand-1-mediated T cell stimulation following Listeria monocytogenes infection. Journal of immunology (Baltimore, Md. : 1950), 189 2, 876-84Rowe, Jared H; Ertelt, James M; Way, Sing Sing 2012. Foxp3(+) regulatory T cells, immune stimulation and host defence against infection. Immunology, 136 1, 1-10Rowe, Jared H; Ertelt, James M; Xin, Lijun; Way, Sing Sing 2012. Pregnancy imprints regulatory memory that sustains anergy to fetal antigen. Nature, 490 7418, 102-6Rowe, Jared H; Ertelt, James M; Xin, Lijun; Way, Sing Sing 2012. Listeria monocytogenes cytoplasmic entry induces fetal wastage by disrupting maternal Foxp3+ regulatory T cell-sustained fetal tolerance. PLoS pathogens, 8 8, e1002873Ertelt, James M; Johanns, Tanner M; Mysz, Margaret A; Nanton, Minelva R; Rowe, Jared H; Aguilera, Marijo N; Way, Sing Sing 2011. Selective culling of high avidity antigen-specific CD4+ T cells after virulent Salmonella infection. Immunology, 134 4, 487-97Ertelt, James M; Rowe, Jared H; Mysz, Margaret A; Singh, Charanjeet; Roychowdhury, Monika; Aguilera, Marijo N; Way, Sing Sing 2011. Foxp3+ regulatory T cells impede the priming of protective CD8+ T cells. Journal of immunology (Baltimore, Md. : 1950), 187 5, 2569-77Han, Jin-Young; Hanson, David C; Way, Sing Sing 2011. Herpes zoster and meningitis due to reactivation of varicella vaccine virus in an immunocompetent child. The Pediatric infectious disease journal, 30 3, 266-8Johanns, Tanner M; Law, Calvin Y; Kalekar, Lokeshchandra A; O'Donnell, Hope; Ertelt, James M; Rowe, Jared H; Way, Sing Sing 2011. Early eradication of persistent Salmonella infection primes antibody-mediated protective immunity to recurrent infection. Microbes and infection / Institut Pasteur, 13 4, 322-30Rowe, Jared H; Ertelt, James M; Aguilera, Marijo N; Farrar, Michael A; Way, Sing Sing 2011. Foxp3(+) regulatory T cell expansion required for sustaining pregnancy compromises host defense against prenatal bacterial pathogens. Cell host & microbe, 10 1, 54-64Rudd, Brian D; Venturi, Vanessa; Li, Gang; Samadder, Partha; Ertelt, James M; Way, Sing Sing; Davenport, Miles P; Nikolich-Žugich, Janko 2011. Nonrandom attrition of the naive CD8+ T-cell pool with aging governed by T-cell receptor:pMHC interactions. Proceedings of the National Academy of Sciences of the United States of America, 108 33, 13694-9Curtis, Meredith M; Rowell, Emily; Shafiani, Shahin; Negash, Amina; Urdahl, Kevin B; Wilson, Christopher B; Way, Sing Sing 2010. Fidelity of pathogen-specific CD4+ T cells to the Th1 lineage is controlled by exogenous cytokines, interferon-gamma expression, and pathogen lifestyle. Cell host & microbe, 8 2, 163-73Ertelt, James M; Johanns, Tanner M; Rowe, Jared H; Way, Sing Sing 2010. Interleukin (IL)-21-independent pathogen-specific CD8+ T-cell expansion, and IL-21-dependent suppression of CD4+ T-cell IL-17 production. Immunology, 131 2, 183-91Johanns, Tanner M; Ertelt, James M; Lai, Joseph C; Rowe, Jared H; Avant, Ross A; Way, Sing Sing 2010. Naturally occurring altered peptide ligands control Salmonella-specific CD4+ T cell proliferation, IFN-gamma production, and protective potency. Journal of immunology (Baltimore, Md. : 1950), 184 2, 869-76Johanns, Tanner M; Ertelt, James M; Rowe, Jared H; Way, Sing Sing 2010. Regulatory T cell suppressive potency dictates the balance between bacterial proliferation and clearance during persistent Salmonella infection. PLoS pathogens, 6 8, e1001043Rudd, Brian D; Venturi, Vanessa; Smithey, Megan J; Way, Sing Sing; Davenport, Miles P; Nikolich-Zugich, Janko 2010. Diversity of the CD8+ T cell repertoire elicited against an immunodominant epitope does not depend on the context of infection. Journal of immunology (Baltimore, Md. : 1950), 184 6, 2958-65Winstead, Colleen J; Reilly, Cavan S; Moon, James J; Jenkins, Marc K; Hamilton, Sara E; Jameson, Stephen C; Way, Sing Sing; Khoruts, Alexander 2010. CD4+CD25+Foxp3+ regulatory T cells optimize diversity of the conventional T cell repertoire during reconstitution from lymphopenia. Journal of immunology (Baltimore, Md. : 1950), 184 9, 4749-60Curtis, Meredith M; Way, Sing Sing 2009. Interleukin-17 in host defence against bacterial, mycobacterial and fungal pathogens. Immunology, 126 2, 177-85Curtis, Meredith M; Way, Sing Sing; Wilson, Christopher B 2009. IL-23 promotes the production of IL-17 by antigen-specific CD8 T cells in the absence of IL-12 and type-I interferons. Journal of immunology (Baltimore, Md. : 1950), 183 1, 381-7Ertelt, James M; Rowe, Jared H; Johanns, Tanner M; Lai, Joseph C; McLachlan, James B; Way, Sing Sing 2009. Selective priming and expansion of antigen-specific Foxp3- CD4+ T cells during Listeria monocytogenes infection. Journal of immunology (Baltimore, Md. : 1950), 182 5, 3032-8Rowe, Jared H; Johanns, Tanner M; Ertelt, James M; Lai, Joseph C; Way, Sing Sing 2009. Cytotoxic T-lymphocyte antigen 4 blockade augments the T-cell response primed by attenuated Listeria monocytogenes resulting in more rapid clearance of virulent bacterial challenge. Immunology, 128 1 Suppl, e471-8Asplin, Iain R; Carl, David J; Way, Sing Sing; Jones, Amanda L 2008. Role of Toll-like receptor 2 in innate resistance to Group B Streptococcus. Microbial pathogenesis, 44 1, 43-51Muller, William J; Orgun, Nural N; Dong, Lichun; Koelle, David M; Huang, Meei-Li; Way, Sing Sing 2008. Recombinant Listeria monocytogenes expressing an immunodominant peptide fails to protect after intravaginal challenge with herpes simplex virus-2. Archives of virology, 153 6, 1165-9Orgun, Nural N; Mathis, Meredith A; Wilson, Christopher B; Way, Sing Sing 2008. Deviation from a strong Th1-dominated to a modest Th17-dominated CD4 T cell response in the absence of IL-12p40 and type I IFNs sustains protective CD8 T cells. Journal of immunology (Baltimore, Md. : 1950), 180 6, 4109-15Orgun, Nural N; Way, Sing Sing 2008. A critical role for phospholipase C in protective immunity conferred by listeriolysin O-deficient Listeria monocytogenes. Microbial pathogenesis, 44 2, 159-63Rowe, Jared H; Johanns, Tanner M; Ertelt, James M; Way, Sing Sing 2008. PDL-1 blockade impedes T cell expansion and protective immunity primed by attenuated Listeria monocytogenes. Journal of immunology (Baltimore, Md. : 1950), 180 11, 7553-7Kollmann, Tobias R; Reikie, Brian; Blimkie, Darren; Way, Sing Sing; Hajjar, Adeline M; Arispe, Kiea; Shaulov, Angela; Wilson, Christopher B 2007. Induction of protective immunity to Listeria monocytogenes in neonates. Journal of immunology (Baltimore, Md. : 1950), 178 6, 3695-701Orr, Mark T; Orgun, Nural N; Wilson, Christopher B; Way, Sing Sing 2007. Cutting edge: recombinant Listeria monocytogenes expressing a single immune-dominant peptide confers protective immunity to herpes simplex virus-1 infection. Journal of immunology (Baltimore, Md. : 1950), 178 8, 4731-5Way, Sing Sing; Havenar-Daughton, Colin; Kolumam, Ganesh A; Orgun, Nural N; Murali-Krishna, Kaja 2007. IL-12 and type-I IFN synergize for IFN-gamma production by CD4 T cells, whereas neither are required for IFN-gamma production by CD8 T cells after Listeria monocytogenes infection. Journal of immunology (Baltimore, Md. : 1950), 178 7, 4498-505Way, Sing Sing; Wilson, Christopher B 2005. The Mycobacterium tuberculosis ESAT-6 homologue in Listeria monocytogenes is dispensable for growth in vitro and in vivo. Infection and immunity, 73 9, 6151-3Darveau, Richard P; Pham, Thu-Thao T; Lemley, Kayde; Reife, Robert A; Bainbridge, Brian W; Coats, Stephen R; Howald, William N; Way, Sing Sing; Hajjar, Adeline M 2004. Porphyromonas gingivalis lipopolysaccharide contains multiple lipid A species that functionally interact with both toll-like receptors 2 and 4. Infection and immunity, 72 9, 5041-51Kollmann, Tobias R; Way, Sing Sing; Harowicz, Heidi L; Hajjar, Adeline M; Wilson, Christopher B 2004. Deficient MHC class I cross-presentation of soluble antigen by murine neonatal dendritic cells. Blood, 103 11, 4240-2Way, Sing Sing; Thompson, Lucas J; Lopes, Jared E; Hajjar, Adeline M; Kollmann, Tobias R; Freitag, Nancy E; Wilson, Christopher B 2004. Characterization of flagellin expression and its role in Listeria monocytogenes infection and immunity. Cellular microbiology, 6 3, 235-42Way, Sing Sing; Wilson, Christopher B 2004. Cutting edge: immunity and IFN-gamma production during Listeria monocytogenes infection in the absence of T-bet. Journal of immunology (Baltimore, Md. : 1950), 173 10, 5918-22Shetron-Rama, Lynne M; Mueller, Kimberly; Bravo, Juan M; Bouwer, H G Archie; Way, Sing Sing; Freitag, Nancy E 2003. Isolation of Listeria monocytogenes mutants with high-level in vitro expression of host cytosol-induced gene products. Molecular microbiology, 48 6, 1537-51Way, Sing Sing; Kollmann, Tobias R; Hajjar, Adeline M; Wilson, Christopher B 2003. Cutting edge: protective cell-mediated immunity to Listeria monocytogenes in the absence of myeloid differentiation factor 88. Journal of immunology (Baltimore, Md. : 1950), 171 2, 533-7Kinder, Jeremy M; Jiang, Tony T; Clark, Dayna R; Chaturvedi, Vandana; Xin, Lijun; Ertelt, James M; Way, Sing Sing . Pregnancy-induced maternal regulatory T cells, bona fide memory or maintenance by antigenic reminder from fetal cell microchimerism? Chimerism, 5 1, 16-9